CN105496814B - A kind of 4D nail polish glue and its application method - Google Patents
A kind of 4D nail polish glue and its application method Download PDFInfo
- Publication number
- CN105496814B CN105496814B CN201510874038.6A CN201510874038A CN105496814B CN 105496814 B CN105496814 B CN 105496814B CN 201510874038 A CN201510874038 A CN 201510874038A CN 105496814 B CN105496814 B CN 105496814B
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- Prior art keywords
- parts
- nail
- nail polish
- polish glue
- glue
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- 238000000034 method Methods 0.000 title claims abstract description 19
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- 125000004494 ethyl ester group Chemical group 0.000 claims abstract description 16
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 claims abstract description 16
- WKGDNXBDNLZSKC-UHFFFAOYSA-N oxido(phenyl)phosphanium Chemical class O=[PH2]c1ccccc1 WKGDNXBDNLZSKC-UHFFFAOYSA-N 0.000 claims abstract description 15
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000002131 composite material Substances 0.000 claims description 93
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- 238000003756 stirring Methods 0.000 claims description 52
- 239000000203 mixture Substances 0.000 claims description 49
- 238000002360 preparation method Methods 0.000 claims description 37
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- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical compound ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 description 1
- 241001045770 Trichophyton mentagrophytes Species 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000002009 allergenic effect Effects 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 229960005193 avobenzone Drugs 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000005660 chlorination reaction Methods 0.000 description 1
- OAIVIYSBZFEOIU-UHFFFAOYSA-N chloroform;propan-2-one Chemical compound CC(C)=O.ClC(Cl)Cl OAIVIYSBZFEOIU-UHFFFAOYSA-N 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000006482 condensation reaction Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000001723 curing Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000013530 defoamer Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000004807 desolvation Methods 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000007888 film coating Substances 0.000 description 1
- 238000009501 film coating Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 235000011167 hydrochloric acid Nutrition 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 239000006166 lysate Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 230000005311 nuclear magnetism Effects 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 238000000016 photochemical curing Methods 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 238000004237 preparative chromatography Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 235000015170 shellfish Nutrition 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
- A61Q3/02—Nail coatings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/16—Peri-condensed systems
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2351/00—Characterised by the use of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives of such polymers
- C08J2351/08—Characterised by the use of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a kind of 4D nail polish glue and its application method of cooperated with LED nail lamp.It includes 11; 14 2 dislike 2; the olefin(e) acid 4 of 9 diaza heptadecane 16; 4; 6,16 tetramethyl 10,15 dioxo 2 [(acrylic of 2 methyl, 1 oxo 2) oxo] ethyl ester, compound of formula I, acrylate quasi-oligomer, 1 hydroxycyclohexyl phenyl ketone and double phenyl phosphine oxides (2; 4,6 trimethylbenzoyls) etc. material.The nail factice possesses the two-in-one effect of primer sealing, and flood easily divests during removal, and color is full, and brightness is high, and has good amalgamation with nail, has preferable anti-microbial property, health environment-friendly.
Description
Technical field
Field is synthetically generated the present invention relates to cosmetics, more particularly to a kind of 4D nail polish glue and its cooperated with LED nail lamp
Application method.
Background technology
Nail polish glue is all a very popular makeups product in the women of all age group, and people seeking beauty is applied
It is put on nail, to which nail can be made colourful；The nail polish glue brand that currently there are is various, very different.
Publication No. CN102908266A Chinese invention patent application discloses a kind of Environmental-friendnail nail enamel and its preparation side
Method, the Environmental-friendnail nail enamel include emulsion, film forming agent, aqueous, environmental protective mill base and deionized water；Wherein, the list that prepared by the emulsion
Body includes butyl acrylate, styrene, methacrylic acid and vinyl hydroxy silicone oil；The initiator is azodiisobutyronitrile；
Although the patent claims that its nail polish is environment-friendly type nail polish, but true really not so.
Publication No. CN102552059A Chinese invention patent application discloses a kind of low stimulation nail polish, the nail polish
Based on alcohols solvent and alcohols film forming agent, then it is equipped with the stirring of the additives such as thickener, suspending agent, plasticizer, paint box essence
Mix；But the nail polish has very strong excitant, contact skin also has certain burn sense and injury.
Meanwhile in the prior art not publicly unsoundness environmental protection, the nail polish glue that is easily peeled off or tears.
The content of the invention
It is an object of the invention to provide a kind of 4D nail polish glue, and it has quick solidifying and is easily peeled off or tears, stable performance
It is water-fastness, have no irritating odor, health environment-friendly, without water cleaning can also reach noresidue the advantages of.
The present invention above-mentioned technical purpose technical scheme is that：
A kind of 4D nail polish glue for being applicable LED illumination curing, include the component of following parts by weight：
11, the 14- bis- of 38-45 parts dislikes -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyls -10,15- bis-
Oxo -2- [(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
The compound of formula I of 0.02-0.04 parts；
The acrylate quasi-oligomer of 25-29 parts；
The 1- hydroxycyclohexyl phenyl ketones of 2.4-2.9 parts；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyl) of 2.5-3.1 parts；
The hydroxyethyl methacrylate of 11-13 parts；
1.1-1.4 the triethanolamine of part；
The laureth -21 of 0.7-0.8 parts；
1.5-2.8 part micas；
Its compounds of formula I is shown below：
As a preference of the present invention, in the nail polish glue containing the red 0.9-1.6 parts of C117200, the red 0.5-1 parts of C15850,
The black 2.8-3.6 parts of C177499, C177492 Huang 0.15-0.22 parts, CN15985 Huang 0.14-0.21 parts, C177510 indigo plants 1.03-
The colouring agent of one or more of 1.35 parts or C177891 white 2.15-2.65 parts.
As a preference of the present invention, contain mediation glue 6-8 parts in the nail polish glue；The mediation glue is by following parts by weight
Component forms：
Polyacrylate -2- cross-linked polymer 42-48 parts；Benzophenone 7-10 parts；EMA 23-28 parts；It is poly-
Dimethyl siloxane 8-16 parts；Trimethylolpropane trimethacrylate 10-15 parts.
As a preference of the present invention, contain first composite regulator 7-9 parts and the second composite regulator in the nail polish glue
8-10 parts；
First composite regulator includes the isostearates of polyglycereol -2- three of in mass ratio 1: 3-4: 1-2 composition, third
Triol and AVC mixture；And
Second composite regulator includes two isooctadecanol malic acid fat, the first silicon of in mass ratio 1: 2-4: 1-3 composition
It is alkylated silica and butylmethoxydibenzoylmethane mixture.
As a preference of the present invention, contain triplex conditioning agent 4-6 parts in the nail polish glue；The triplex regulation
Agent includes deacetylation chitosan, molecular weight of the deacetylation in 70-80% of in mass ratio 1: 0.5-0.8: 1.3-1.7 composition
The mixture of oligosaccharide and DPnB for 1800-2000 dalton.
As a preference of the present invention, the preparation method of the deacetylation chitosan is：By chitin in mass concentration 40-
In 50% alkali lye 135-145 DEG C heating 1-2h, be made deacetylation 70-80%, molecular weight be 20000-35000 dongles
The chitosan to pause.
As a preference of the present invention, the preparation method of the polyacrylate -2- cross-linked polymers is：
(1) prepared polymer P (MMA-MAh)-PEG600030-40 parts, regulation liquid 40-60 parts form and just mixed by weight
Liquid；Described regulation liquid is to include the sodium perchlorate that concentration is 0.4-0.7mol/L and the N- butyl that concentration is 0.3-0.8mol/L
The carbonic allyl ester solution of benzimidazole；MMA in described polymer P (MMA-MAh)-PEG4000 is methyl methacrylate
Ester, MAh are maleic anhydrides, and P (MMA-MAh) is the copolymer of methyl methacrylate and maleic anhydride, and PEG6000 is molecular weight
For 6000 polyethylene glycol；
(2) dihydroxystearic acid of 2-7 parts ten is added in the just mixed liquid, is heated to 30-45 DEG C under nitrogen protection instead
Answer 5-9min；
(3) polyacrylate -2- cross-linked polymers are obtained after being dried with deionized water rinsing.
As a preference of the present invention, contain the 4th composite regulator 1-4 parts in the nail polish glue；
4th composite regulator is made up of the raw material of following parts by weight：
Cetanol caprylate 28-33 parts, glutaric acid 15-18 parts, butantriol 8-10 parts, Zinc Oxide 5-7 parts, magnesia 3-5
Part, neoprene 18-23 parts, elastic plastic 70-95 parts, softening oil 2-3 parts, dimethyl carbonate 15-20 parts and ethylbenzene 22-28 parts；
The elastic plastic includes the first elastic plastic and the second elastic plastic by weight 1: 2-5 mixing；
Emulsion acrylic resin, the 12- that the solids content that first elastic plastic includes 15-30 part weight is 60-75%
The EVA breasts that 15 parts of aqueous polyurethanes, the acrylic resin powder of 5-8 part weight, the solids content of 2-6 part weight are 20-35%
The chlorinated polypropylene of liquid and 1-4 part weight；
The preparation method of second elastic plastic is：By 1-5 parts mass concentration be 20-25% polyvinyl alcohol water solution and
The 20-30 parts 15-20wt% aqueous polyurethane aqueous solution is heated up to 60-80 DEG C, is cooled to after 30-50 DEG C and adds 10-15 parts
Acrylate, then add the lithium hydroxide of 0.1-0.2 parts and be warming up to 100-110 DEG C, add 5-8 parts sclerotin albumen,
The rosin, the eugenol of 2-4 parts of 6-9 parts, and 45-55 DEG C is cooled to after insulation reaction 3-5 hours, then add 6-8 parts
The OPEO of bamboo charcoal micropowder, the negative ion powder of 2-7 parts and 10-13 parts, stir 1-1.5 hours, cooling, institute is made
State the second elastic plastic.
As a preference of the present invention, the preparation method of this kind of nail polish glue is：Add successively under corresponding parts by weight in order
State component
11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2-
[(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
Compound of formula I；
Acrylate quasi-oligomer；
1- hydroxycyclohexyl phenyl ketones；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
Hydroxyethyl methacrylate；
Triethanolamine；
Laureth -21；
Mica；
High-speed stirred is well mixed after the mixing of above composition, adds all the second composite regulator stirring 10-
15min, then add all first composite regulators and continue to stir 3-6min；Then all mediation glue stirrings are added
5-9min, it is subsequently added into all the 4th composite regulators and continues to stir 2-5min；It is eventually adding all triplex
Conditioning agent continues to stir 1-4min, obtains finished product.
As a preference of the present invention, the preparation method of the triethanolamine is：
(1) oxirane, ammoniacal liquor are sent into reactor, in 36-38 DEG C of reaction temperature, reaction pressure 100-300kPa
Under, carry out condensation reaction generation one, two, triethanolamine mixed liquor；
(2) at 100-110 DEG C after dehydration concentrates, three vacuum rectification towers is sent into and are evaporated under reduced pressure, by different boilings
Point interception cut, so as to obtain triethanolamine semi-finished product；
(3) removal of impurity is removed with steam distillation, and adding sodium hydroxide makes triethanolamine be separated out into alkali metal salt, point
From rear neutralization, then carry out being evaporated under reduced pressure to triethanolamine sterling.
Another object of the present invention is to provide a kind of application method of 4D nail polish glue cooperated with LED nail lamp, including it is following
Step：
(1) nail surface is cleaned；
(2) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiation 60
- 120 seconds seconds；
(3) on nail surface it is frivolous, be evenly coated with one layer of nail polish glue；LED nail lamps to nail surface irradiate 60 seconds-
120 seconds；This step is according to demand or hobby can repeat 1-2 times；
(4) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiation 60
- 120 seconds seconds.
In summary, the invention has the advantages that：
11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2-
[(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester, with acrylate quasi-oligomer, both materials are in nail polish of the present invention
It is main in glue to play sizing colloid action.
1- hydroxycyclohexyl phenyl ketones, with double phenyl phosphine oxides (2,4,6- trimethylbenzoyl), both materials
Mainly play light-sensitive emulsion in nail polish glue of the present invention, nail polish glue can be kept stable bright beautiful, prevent xanthochromia；And prior art
In nail polish glue, nail easily thinning jaundice is uneconomical and it also requires once conserve in addition.
Hydroxyethyl methacrylate, in the present invention mainly rise solvent action, while with the material 11,14- of specific deal
Two dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2- [(2- methyl isophthalic acid-oxos -
2- acrylic) oxo] ethyl ester and acrylate quasi-oligomer, and the material common combination of remaining specified weight part, it can reach fast
Speed solidification, therefore instant invention is especially suited for pass through LED manicure light irradiations, 60 seconds can film-formings of general illumination；LED manicures
Light irradiation is more long, and persistence is higher；Meanwhile the present invention is easy to flood easily to divest in removal.
Disadvantage existing for existing strippable water-soluble nail polish glue is easily to touch aquation to open, and nail polish colloidality energy of the present invention
Stablize water-fastness, while be also easily peeled off or tear, have no irritating odor, health environment-friendly；The film that light is formed after drying applies
Layer, stable performance, and color is full, color and persistence are good, can maintain one to twice intact nothing more than week at least
Damage.
Triethanolamine and laureth -21, be advantageous to improve nail polish glue moistening effect, make the more sparkling and crystal-clear water of nail polish glue
It is bright.
Mica, be advantageous to improve the physics and stable chemical performance of nail polish glue of the present invention, while be beneficial to make first of the present invention
Factice has more glossiness.
Compound of formula I is the native compound that the present inventor extracts from ginkgo leaf, the invasion and attack available for preventing and treating fungi.
During nail colour to be changed, it is only necessary to torn after nail tip stripping, reach effect week thrown week and changed, use
It is very convenient safe and healthy；Wrap up without unloading first water and tinfoil during removal, removed or file abrades without being pushed using manicure.
Flood easily divests during nail polish glue removal of the present invention, has nail maintenance effect, has enhancing for fragile nail
Protective effect, nail layering easy fracture problem can be improved comprehensively, while nail polish glue of the present invention and nail surface amalgamation are good, apply
After complete, except the change of nail colour, feel comfortable just as no painting nail polish glue.
Dimethyl silicone polymer of the present invention is a kind of organosilicon, has good chemical stability and physiologically active,
It is a kind of material of the health environment-friendly for human body；Have the work of levelling agent, remover and defoamer concurrently in nail polish glue of the present invention
With.
Present invention mediation glue, has armor effect；After being added to nail polish glue, beneficial to nail polish glue can rapid draing, and property
Can stablize it is water-fastness, while beneficial to peel off or tear, have no irritating odor, health environment-friendly, without water cleaning can also reach nothing
Residual.
Colouring agent can reconcile into not same color by a variety of collocation；And there is excellent wearability and richness, often
Individual women can select color according to oneself hobby, occasion, the nail polish glue is painted on nail, reach armor manicure
Two-in-one effect.
Have after the first composite regulator proportioning of the present invention and excellent disperse, coagulate the soup and anti-wear and wear-resistant performance；Second is multiple
There is anti-oxidant and bright and clean function after closing conditioning agent proportioning；Two kinds of composite regulators are combined and can reach Synergistic
Effect；According to the nail polish glue of present invention proportioning composition, high temperature resistant (more than 38 DEG C) and the property of low temperature resistant (less than -10 DEG C) are had concurrently
Can, manufactured nail polish glue is used for a variety of special occasions, such as hot seashore or the north of cold, retention property stabilization.
Wherein, DPnB is dipropylene；Triplex conditioning agent of the invention has good film forming and abrasion resistance；
There are active hydroxyl and amino in chitosan macromolecular, they have stronger chemical reaction ability, and it is much excellent to assign chitosan
Different chemical property and physiologically active, the effect of being cross-linked with each other of oligomeric sugar layer and chitosan layer can prevent that degradation of chitosan is too fast；
Three kinds of composite regulators are combined and can reach synergistic function；Meanwhile chitosan again can with equally have it is good
The dimethyl silicone polymer of good physiologically active plays synergistic function.
Chitin be from the shell of the shellfish such as shrimp, crab and bacterium, algae rudimentary plant cell membrane in extract
Natural macromolecular material be the second largest biologically-derived resource that cellulose is only second in nature, wide material sources, be excellent
Renewable resource, today increasingly deficient in face of resource, new renewable resource is made full use of to become particularly important, chitin
Received much concern because of its excellent performance and renewable；Chitin, chitosan and their derivative to bacterium, yeast,
The microorganisms such as fungi have good inhibiting effect.
Polyacrylate -2- the cross-linked polymers prepared using the present invention have excellent film forming, hot property and size
Stability, beneficial to making nail polish glue easily solidify under LED nail lamp illumination and be easily peeled off or tear, there is enough brightness,
Have no irritating odor, health environment-friendly, noresidue can also be reached without water cleaning.
Using the 4th composite regulator of the present invention, there is the advantages of tack is good, fastness is high, add the 4th compound regulation
Agent, coordinate remaining specified weight part material, nail polish glue of the present invention is possessed the two-in-one effect of primer sealing, and be beneficial to make
Used time is peelable tearable, has no irritating odor, health environment-friendly, can also reach noresidue without water cleaning.
When nail polish glue mixes preparation, the order of various composition addition has an impact to the performance of product；According to the present invention
Nail polish glue prepared by method order of addition is under the requirement for meeting to be easily peeled off or tear, beneficial to raising stability and wearability.
Therefore, the invention provides a kind of healthy LED 4D application methods, its advantage mainly has, namely present subject matter
Described in 4D, i.e. 4 primary efficacies, refer to：
1st, nail polish glue of the present invention possesses the two-in-one effect of primer sealing；
2nd, after nail polish glue of the present invention is coated on nail, using LED nail lamp photocurings, general 60 seconds are curable film-forming, are held
Long property is good, and duration was up to 1-2 weeks；First water and tinfoil parcel need not be unloaded during removal, is removed or steel without being pushed using manicure
File abrades；Flood easily divests during removal, has nail maintenance effect, has enhancing protective effect, energy for fragile nail
It is enough to improve nail layering easy fracture problem comprehensively；It is easy to the needs for meeting different occasion different colours, has no irritating odor, health
Environmental protection, noresidue can also be reached without water cleaning；
3rd, nail polish glue of the present invention can be presented color thousand and be in, colourful, can refer to color use directly as colour, and have
Excellent wearability and richness, color is full, the light of extreme, glitters very much；And nail polish glue of the present invention has well with nail
Amalgamation, after being painted with, except the change of nail colour, feel comfortable just as no painting nail polish glue；
4th, there is no light trigger in inventive formulation, there is no ethereal oil solvent, also without benzene, formaldehyde, ethyl acetate,
DBP class harmful substances, and with environmental protection, quick-drying, be not required to illumination, film forming stably the advantages of, and with the addition of in inventive formulation from
The compound of formula I extracted in ginkgo leaf, and the use of chitin, chitosan and their derivative, to bacterium, yeast, fungi
There is good inhibiting effect Deng microorganism；Therefore, health environment-friendly of the present invention, has no irritating odor, small to human injury's property, and
Acted on good armor.
Embodiment
Below by embodiment, the invention will be further described.It should be understood that methods described of the embodiment of the present invention
It is only used for the explanation present invention, rather than limitation of the present invention, to preparation side of the invention under the concept thereof of the present invention
The simple modifications of method belong to the scope of protection of present invention.All raw materials and solvent used in embodiment are purchased from
Sigma Biochemical and Organic Compounds for Research and Diagnostic Clinical
Reagents companies.
The preparation embodiment of compound of formula I：
Using Folium Ginkgo as raw material, crushed and soaked and extracted 2~4 times with ethanol, each 12h~72h, will be extracted
Liquid merges, filters and the ginkgo biloba p.e medicinal extract is obtained after concentrating；Wherein ethanol: ginkgo leaf=3~4: 1, weight ratio.
By 60~120 mesh after above-mentioned ginkgo biloba p.e medicinal extract acetone solution with 2~5 times of weight for the medicinal extract
Dry column-packing after silica gel mixing, grade chloroform-methanol solution that 9: 1,8: 2,7: 3,6: 4,5: 5 are then followed successively by with volume ratio enter
Row gradient elution, the eluent obtained when wherein being eluted with the chloroform-methanol that volume ratio is 9: 1 is collected, referred to as first washes
De- liquid；Above-mentioned first eluent silica gel column chromatography is continued to separate, 15: 1,10: 1,5: 1,2: 1 chlorine is followed successively by with volume ratio
Imitative-acetone soln carries out gradient elution, and the eluent obtained when the chloroform-acetone solution that wherein volume is 10: 1 is eluted is referred to as
Second eluent；Above-mentioned second eluent silica gel column chromatography is continued to separate, 9: 1,8: 2,7: 3,6 are followed successively by with volume ratio:
4th, 5: 5 petroleum ether-ethyl acetate solution carries out gradient elution, wherein volume ratio will be eluted for 7: 3 petroleum ether-ethyl acetate
When obtained eluent be referred to as the 3rd eluent.
Above-mentioned 3rd eluent is passed through into high pressure liquid chromatography (reversed-phase preparative chromatography of the pressure in 5-15Mpa) to be separated
Purifying, the high pressure liquid chromatography use 21.2mm × 250mm, 5 μm of C18Chromatographic column, mobile phase are that 60wt% methanol is water-soluble
Liquid, flow rate of mobile phase 12mL/min, UV-detector Detection wavelength are 374nm, each μ of sample introduction 60~150 of the 3rd eluent
L, eluent corresponding when chromatographic peak retention time after each sample introduction is 31min is collected, the Formulas I is produced after desolvation
Compound
After obtaining above-mentioned compound of formula I, methanol solution can be again dissolved in, and using methanol solution as mobile phase, by solidifying
Glue post carries out chromatography, can further purify the compound of formula I.
Formula I is yellow powder；Following ultraviolet spectras, infrared spectrum and hydrogen for listing compound of formula I
The key structural feature peak of nuclear-magnetism.
Ultraviolet spectra (solvent is methanol)：λmax(log ε) 210 (4.36), 266 (3.82), 374 (3.68) nm；
Infrared spectrum (pressing potassium bromide troche)：vmax3452,2924,2615,1668,1612,1516,1437,1316,1247,
1182,1083,1022,868,722cm-1；
1H NMR (500MHz, CDCl3, ppm) and δ：10.7 (s-OH), 9.48 (s-OH) 6.28-7.52 (d ,-CH 5H),
6.57 (s, 1H), 6.18 (s 1H), 3.27 (d ,-CH2), 1.99-3.81 (d ,-CH39H).
The preparation embodiment of nail polish glue：
The glue that reconciles is formulated 1：48 parts of polyacrylate -2- cross-linked polymerics；10 parts of benzophenone；28 parts of EMA；
16 parts of dimethyl silicone polymer；15 parts of trimethylolpropane trimethacrylate.
The glue that reconciles is formulated 2：42 parts of polyacrylate -2- cross-linked polymers；7 parts of benzophenone；23 parts of EMA；
8 parts of dimethyl silicone polymer；10 parts of trimethylolpropane trimethacrylate.
The glue that reconciles is formulated 3：45 parts of polyacrylate -2- cross-linked polymers；8 parts of benzophenone；26 parts of EMA；
13 parts of dimethyl silicone polymer；14 parts of trimethylolpropane trimethacrylate.
First composite regulator formula 1：
The isostearates of polyglycereol -2- three, glycerine and AVC in mass ratio 1:
3: 2 mixing compositions.
First composite regulator formula 2：
The isostearates of polyglycereol -2- three, glycerine and AVC in mass ratio 1:
4: 1 mixing compositions.
First composite regulator formula 3：
The isostearates of polyglycereol -2- three, glycerine and AVC in mass ratio 1:
3: 1 mixing compositions.
Second composite regulator formula 1：Two isooctadecanol malic acid fat, silylated silica and butylmethoxy hexichol
The mixing composition of formyl methylmethane in mass ratio 1: 2: 3.
Second composite regulator formula 2：Two isooctadecanol malic acid fat, silylated silica and butylmethoxy hexichol
The mixing composition of formyl methylmethane in mass ratio 1: 4: 1.
Second composite regulator formula 3：Two isooctadecanol malic acid fat, silylated silica and butylmethoxy hexichol
The mixing composition of formyl methylmethane in mass ratio 1: 3: 2.
Triplex conditioner formulations 1：Deacetylation 70% deacetylation chitosan, molecular weight be 1800 dalton
Oligosaccharide and DPnB in mass ratio 1: 0.5: 1.7 mixing composition.
Triplex conditioner formulations 2：Deacetylation 80% deacetylation chitosan, molecular weight be 2000 dalton
Oligosaccharide and DPnB in mass ratio 1: 0.8: 1.3 mixing composition.
Triplex conditioner formulations 3：Deacetylation 75% deacetylation chitosan, molecular weight be 1900 dalton
Oligosaccharide and DPnB in mass ratio 1: 0.6: 1.5 mixing composition.
4th composite regulator formula 1：
28 parts of cetanol caprylate, 15 parts of glutaric acid, 8 parts of butantriol, 5 parts of Zinc Oxide, 3 parts of magnesia, neoprene 18
Part, 70 parts of elastic plastic, 2 parts of softening oil, 15 parts of dimethyl carbonate and 22 parts of ethylbenzene；
Elastic plastic includes the first elastic plastic and the second elastic plastic by weight 1: 3 mixing；
First elastic plastic includes emulsion acrylic resin, 12 part water-based poly- ammonia of the solids content of 15 parts of weight for 68%
The chlorination of EVA emulsions and 1 part of weight that ester, the acrylic resin powder of 5 parts of weight, the solids content of 2 parts of weight are 29%
Polypropylene.
4th composite regulator formula 2：
33 parts of cetanol caprylate, 18 parts of glutaric acid, 10 parts of butantriol, 7 parts of Zinc Oxide, 5 parts of magnesia, neoprene 23
Part, 95 parts of elastic plastic, 3 parts of softening oil, 20 parts of dimethyl carbonate and 28 parts of ethylbenzene；
Elastic plastic includes the first elastic plastic and the second elastic plastic by weight 1: 2 mixing；
Emulsion acrylic resin that the solids content that first elastic plastic includes 30 parts of weight is 60%, 15 parts of weight it is water-based
The EVA emulsions and 4 parts of weight that polyurethane, the acrylic resin powder of 8 parts of weight, the solids content of 6 parts of weight are 20%
Chlorinated polypropylene.
4th composite regulator formula 3：
30 parts of cetanol caprylate, 16 parts of glutaric acid, 9 parts of butantriol, 6 parts of Zinc Oxide, 4 parts of magnesia, neoprene 20
Part, 80 parts of elastic plastic, 2.5 parts of softening oil, 18 parts of dimethyl carbonate and 25 parts of ethylbenzene；
Elastic plastic includes the first elastic plastic and the second elastic plastic by weight 1: 3 mixing；
First elastic plastic includes emulsion acrylic resin, 13 part water-based poly- ammonia of the solids content of 20 parts of weight for 75%
Ester, the acrylic resin powder of 7 parts of weight, the solids content of 4 parts of weight are 35% EVA emulsions and the chlorine of 2.5 parts of weight
Change polypropylene.
Embodiment one：
A kind of 4D nail polish glue includes the component of following parts by weight：11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -
4,4,6,16- tetramethyl -10,15- dioxo -2- [(2- methyl isophthalic acids-oxo -2- acrylic) oxo] 38 parts of ethyl ester；
0.02 part of compound of formula I；
25 parts of acrylate quasi-oligomer；
2.4 parts of 1- hydroxycyclohexyl phenyl ketones；
Double 2.5 parts of phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
11 parts of hydroxyethyl methacrylate；
1.1 parts of triethanolamine；
- 210.7 parts of laureth；
1.5 parts of mica；
High-speed stirred is well mixed after the mixing of above composition is made more effect 4D nail polish glue.
The preparation method of the triethanolamine is：
(1) oxirane, ammoniacal liquor are sent into reactor, under 36 DEG C of reaction temperature, reaction pressure 100kPa, contracted
Close reaction generation one, two, triethanolamine mixed liquor；
(2) at 100 DEG C after dehydration concentrates, three vacuum rectification towers is sent into and are evaporated under reduced pressure, are cut by different boiling
Cut is taken, so as to obtain triethanolamine semi-finished product；
(3) removal of impurity is removed with steam distillation, and adding sodium hydroxide makes triethanolamine be separated out into alkali metal salt, point
From rear neutralization, then carry out being evaporated under reduced pressure to triethanolamine sterling.
The application method of the present embodiment cooperated with LED nail lamp, comprises the steps：
(1) nail surface is cleaned；
(2) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiation 60
- 120 seconds seconds；
(3) on nail surface it is frivolous, be evenly coated with one layer of nail polish glue；LED nail lamps to nail surface irradiate 60 seconds-
120 seconds；This step is according to demand or hobby can repeat 1-2 times；
(4) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiation 60
- 120 seconds seconds.
Embodiment two：
A kind of 4D nail polish glue includes the component of following parts by weight：11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -
4,4,6,16- tetramethyl -10,15- dioxo -2- [(2- methyl isophthalic acids-oxo -2- acrylic) oxo] 45 parts of ethyl ester；
0.04 part of compound of formula I；
29 parts of acrylate quasi-oligomer；
2.9 parts of 1- hydroxycyclohexyl phenyl ketones；
Double 3.1 parts of phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
13 parts of hydroxyethyl methacrylate；
1.4 parts of triethanolamine；
- 210.8 parts of laureth；
2.8 parts of mica；
High-speed stirred is well mixed after the mixing of above composition is made more effect 4D nail polish glue.
The preparation method of the triethanolamine is：
(1) oxirane, ammoniacal liquor are sent into reactor, under 38 DEG C of reaction temperature, reaction pressure 300kPa, contracted
Close reaction generation one, two, triethanolamine mixed liquor；
(2) at 110 DEG C after dehydration concentrates, three vacuum rectification towers is sent into and are evaporated under reduced pressure, are cut by different boiling
Cut is taken, so as to obtain triethanolamine semi-finished product；
(3) removal of impurity is removed with steam distillation, and adding sodium hydroxide makes triethanolamine be separated out into alkali metal salt, point
From rear neutralization, then carry out being evaporated under reduced pressure to triethanolamine sterling.
The application method of the present embodiment cooperated with LED nail lamp, comprises the steps：
(1) nail surface is cleaned；
(2) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiation 60
- 120 seconds seconds；
(3) on nail surface it is frivolous, be evenly coated with one layer of nail polish glue；LED nail lamps to nail surface irradiate 60 seconds-
120 seconds；This step is according to demand or hobby can repeat 1-2 times；
(4) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiation 60
- 120 seconds seconds.
Embodiment three：
A kind of 4D nail polish glue includes the component of following parts by weight：11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -
4,4,6,16- tetramethyl -10,15- dioxo -2- [(2- methyl isophthalic acids-oxo -2- acrylic) oxo] 40 parts of ethyl ester；
0.03 part of compound of formula I；
28 parts of acrylate quasi-oligomer；
2.7 parts of 1- hydroxycyclohexyl phenyl ketones；
Double 2.8 parts of phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
12 parts of hydroxyethyl methacrylate；
1.3 parts of triethanolamine；
- 210.8 parts of laureth；
2.5 parts of mica；
High-speed stirred is well mixed after the mixing of above composition is made more effect 4D nail polish glue.
The preparation method of the triethanolamine is：
(1) oxirane, ammoniacal liquor are sent into reactor, under 37 DEG C of reaction temperature, reaction pressure 200kPa, contracted
Close reaction generation one, two, triethanolamine mixed liquor；
(2) at 105 DEG C after dehydration concentrates, three vacuum rectification towers is sent into and are evaporated under reduced pressure, are cut by different boiling
Cut is taken, so as to obtain triethanolamine semi-finished product；
(3) removal of impurity is removed with steam distillation, and adding sodium hydroxide makes triethanolamine be separated out into alkali metal salt, point
From rear neutralization, then carry out being evaporated under reduced pressure to triethanolamine sterling.
The application method of the present embodiment cooperated with LED nail lamp, comprises the steps：
(1) nail surface is cleaned；
(2) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiation 60
- 120 seconds seconds；
(3) on nail surface it is frivolous, be evenly coated with one layer of nail polish glue；LED nail lamps to nail surface irradiate 60 seconds-
120 seconds；This step is according to demand or hobby can repeat 1-2 times；
(4) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiation 60
- 120 seconds seconds.
Example IV：
With embodiment one except that containing reconciling 6 parts of glue, 7 parts of the first composite regulator and second in nail polish glue
8 parts of composite regulator；Wherein, the first composite regulator is made according to the first composite regulator formula 1, and the second composite regulator is pressed
It is made according to the second composite regulator formula 1, the glue that reconciles is made according to mediation glue formula 1.
It is prepared by nail polish glue：Add the material in embodiment one and then add all the second composite regulator stirrings
10min, then add all first composite regulators and continue to stir 3min；Then all mediation glue stirrings are added
5min, obtain finished product.
As needed, CI17200 red 0.9 part, 15850 red 5 parts of CI, 77499 black 2.8 parts of CI, CI can be added
Any one during 77492 is yellow 0.15 part, CI 15985 is yellow 0.14 part, CI 77510 is blue 1.03 parts or CI 77891 white 2.65 parts
Toner, the nail polish glue with enough brightness of different colours is made.
Embodiment five：
With embodiment two except that containing reconciling 8 parts of glue, 9 parts of the first composite regulator and second in nail polish glue
10 parts of composite regulator；Wherein, the first composite regulator is made according to the first composite regulator formula 2, the second composite regulator
It is made according to the second composite regulator formula 2, the glue that reconciles is made according to mediation glue formula 2.
It is prepared by nail polish glue：Add the material in embodiment one and then add all the second composite regulator stirrings
15min, then add all first composite regulators and continue to stir 6min；Then all mediation glue stirrings are added
9min, obtain finished product.
As needed, CI17200 red 0.9 part, 15850 red 5 parts of CI, 77499 black 2.8 parts of CI, CI can be added
Any one during 77492 is yellow 0.15 part, CI 15985 is yellow 0.14 part, CI 77510 is blue 1.03 parts or CI 77891 white 2.65 parts
Toner, the nail polish glue with enough brightness of different colours is made.
Embodiment six：
With embodiment three except that containing reconciling 7 parts of glue, 8 parts of the first composite regulator and second in nail polish glue
9 parts of composite regulator；Wherein, the first composite regulator is made according to the first composite regulator formula 3, and the second composite regulator is pressed
It is made according to the second composite regulator formula 3, the glue that reconciles is made according to mediation glue formula 3.
It is prepared by nail polish glue：Add the material in embodiment one and then add all the second composite regulator stirrings
15min, then add all first composite regulators and continue to stir 6min；Then all mediation glue stirrings are added
9min, obtain finished product.
As needed, CI17200 red 0.9 part, 15850 red 5 parts of CI, 77499 black 2.8 parts of CI, CI can be added
Any one during 77492 is yellow 0.15 part, CI 15985 is yellow 0.14 part, CI 77510 is blue 1.03 parts or CI 77891 white 2.65 parts
Toner, the nail polish glue with enough brightness of different colours is made.
Embodiment seven：
With example IV except that containing 4 parts of triplex conditioning agent in nail polish glue；Wherein, deacetylation shell
The preparation method of glycan is：Chitin is heated into 1h for 130 DEG C in the alkali lye of mass concentration 40%, deacetylation 70% is made
, molecular weight be 20000 dalton chitosan.Wherein, triplex conditioning agent is made according to triplex conditioner formulations 1
Into.
Preparation method is：Add following components successively in order,
11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2-
[(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
Compound of formula I；
Acrylate quasi-oligomer；
1- hydroxycyclohexyl phenyl ketones；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
Hydroxyethyl methacrylate；
Triethanolamine；
Laureth -21；
Mica；
High-speed stirred is well mixed after the mixing of above composition, adds all the second composite regulator stirring 12min,
Then all first composite regulators are added to continue to stir 4min；Then all mediation glue stirring 7min are added, most
All triplex conditioning agents are added afterwards to continue to stir 3min, obtain finished product.
Embodiment eight：
With embodiment five except that containing 6 parts of triplex conditioning agent in nail polish glue；Wherein, deacetylation shell
The preparation method of glycan is：Chitin is heated into 2h for 150 DEG C in the alkali lye of mass concentration 50%, deacetylation 80% is made
, molecular weight be 35000 dalton chitosan.Wherein, triplex conditioning agent is made according to triplex conditioner formulations 2
Into.
Preparation method is：Add following components successively in order,
11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2-
[(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
Compound of formula I；
Acrylate quasi-oligomer；
1- hydroxycyclohexyl phenyl ketones；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
Hydroxyethyl methacrylate；
Triethanolamine；
Laureth -21；
Mica；
High-speed stirred is well mixed after the mixing of above composition, adds all the second composite regulator stirring 13min,
Then all first composite regulators are added to continue to stir 4min；Then all mediation glue stirring 6min are added, most
All triplex conditioning agents are added afterwards to continue to stir 2min, obtain finished product.
Embodiment nine：
With embodiment six except that containing 5 parts of triplex conditioning agent in nail polish glue；Wherein, deacetylation shell
The preparation method of glycan is：Chitin is heated into 1.2h for 140 DEG C in the alkali lye of mass concentration 45%, deacetylation is made
78%, molecular weight be 25000 dalton chitosan.Wherein, triplex conditioning agent is according to triplex conditioner formulations 3
It is made.
Preparation method is：Addition adds following components successively in order,
11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2-
[(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
Compound of formula I；
Acrylate quasi-oligomer；
1- hydroxycyclohexyl phenyl ketones；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
Hydroxyethyl methacrylate；
Triethanolamine；
Laureth -21；
Mica；
High-speed stirred is well mixed after the mixing of above composition, adds all the second composite regulator stirring 11min,
Then all first composite regulators are added to continue to stir 5min；Then all mediation glue stirring 7min are added, most
All triplex conditioning agents are added afterwards to continue to stir 3min, obtain finished product.
Embodiment ten：
With embodiment seven except that containing 1 part of the 4th composite regulator in nail polish glue.Wherein, the 4th compound tune
Section agent is made according to the 4th composite regulator formula 1.
The preparation method of second elastic plastic is：It is 20% polyvinyl alcohol water solution and 20 parts by 1 part of mass concentration
The 15wt% aqueous polyurethane aqueous solution is heated up to 60 DEG C, is cooled to the acrylate of 10 parts of addition after 30 DEG C, then adds 0.1
Part lithium hydroxide and be warming up to 100 DEG C, add 5 parts of sclerotin albumen, 6 parts of rosin, 2 parts of eugenol, and be incubated
Reaction is cooled to 45 DEG C after 3 hours, then adds 6 parts of bamboo charcoal micropowder, 2 parts of negative ion powder and 10 parts of octyl phenol polyoxy second
Alkene ether, stir 1 hour, cooling, second elastic plastic is made.
It is prepared by nail polish glue：Addition adds following components successively in order,
11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2-
[(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
Compound of formula I；
Acrylate quasi-oligomer；
1- hydroxycyclohexyl phenyl ketones；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
Hydroxyethyl methacrylate；
Triethanolamine；
Laureth -21；
Mica；
High-speed stirred is well mixed after the mixing of above composition, adds all the second composite regulator stirring 10min,
Then all first composite regulators are added to continue to stir 3min；Then all mediation glue stirring 5min are added, are connect
Addition, all the 4th composite regulator continues to stir 2min；All triplex conditioning agents are eventually adding to continue to stir
1min is mixed, obtains finished product.
Wherein, the preparation method of the polyacrylate -2- cross-linked polymers in mediation glue is：
(1) prepared polymer P (MMA-MAh)-PEG600030 parts, 40 parts of regulation liquid form just mixed liquid by weight；Regulation
Liquid is the propene carbonate for including the sodium perchlorate that concentration is 0.4mol/L and the N- butyl benzimidazoles that concentration is 0.8mol/L
Solution；MMA in polymer P (MMA-MAh)-PEG4000 is methyl methacrylate, and MAh is maleic anhydride, P (MMA-MAh)
It is the copolymer of methyl methacrylate and maleic anhydride, PEG6000 is the polyethylene glycol that molecular weight is 6000；
(2) 2 part of ten dihydroxystearic acid is added in first mixed liquid, is heated to 30 DEG C of reaction 5-9min under nitrogen protection；
(3) polyacrylate -2- cross-linked polymers are obtained after being dried with deionized water rinsing.
Detection obtains in performance, and the present embodiment has good water resistance and adhesive force, and water absorption rate is less than 3.2%；For
The detection of traditional performance, it is as follows：It is uniform with common coating method, as much as possible coating；It it is 32 DEG C in temperature, humidity is
50%, seawater immersion is Sanya Yalongwan holiday resort seawater；All washings are general water-washing method, and simulation respectively is had a bath, gone
Hand is dirty, does housework, swims, and for the suds used for general alkaline soap water, washing powder is regular powder, and this experiment uses
Carve board.
After drying 20 minutes, under normal temperature washing state, film still comes off without discoloration, nothing after 65 minutes；In 40 DEG C of temperature
Under water washing state, film still comes off without discoloration, nothing after 70 minutes；Under suds washing state, after 30 minutes film still without
Discoloration, nothing come off；Under washing powder washing state, film is still unchanged after 60 minutes, and nothing comes off；Under seawater soaking state,
Film still comes off without discoloration, nothing after 80 minutes；Under accidental collision impact, film, which has, to come off.
Embodiment 11：
With embodiment eight except that containing 4 parts of the 4th composite regulator in nail polish glue.Wherein, the 4th compound tune
Section agent is made according to the 4th composite regulator formula 2.
The preparation method of second elastic plastic is：It is 25% polyvinyl alcohol water solution and 30 parts by 5 parts of mass concentrations
The 20wt% aqueous polyurethane aqueous solution is heated up to 80 DEG C, is cooled to the acrylate of 15 parts of addition after 50 DEG C, then adds 0.2
Part lithium hydroxide and be warming up to 110 DEG C, add 8 parts of sclerotin albumen, 9 parts of rosin, 4 parts of eugenol, and be incubated
Reaction is cooled to 55 DEG C after 5 hours, then adds 8 parts of bamboo charcoal micropowder, 7 parts of negative ion powder and 13 parts of octyl phenol polyoxy second
Alkene ether, stir 1.5 hours, cooling, second elastic plastic is made.
The preparation method of the nail polish glue is：Addition adds following components successively in order,
11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2-
[(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
Compound of formula I；
Acrylate quasi-oligomer；
1- hydroxycyclohexyl phenyl ketones；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
Hydroxyethyl methacrylate；
Triethanolamine；
Laureth -21；
Mica；
High-speed stirred is well mixed after the mixing of above composition, adds all the second composite regulator stirring 15min,
Then all first composite regulators are added to continue to stir 6min；Then all mediation glue stirring 9min are added, are connect
Addition, all the 4th composite regulator continues to stir 5min；All triplex conditioning agents are eventually adding to continue to stir
4min is mixed, obtains finished product.
Wherein, the preparation method of the polyacrylate -2- cross-linked polymers in mediation glue is：
(1) prepared polymer P (MMA-MAh)-PEG600040 parts, 60 parts of regulation liquid form just mixed liquid by weight；Regulation
Liquid is the propene carbonate for including the sodium perchlorate that concentration is 0.7mol/L and the N- butyl benzimidazoles that concentration is 0.3mol/L
Solution；MMA in polymer P (MMA-MAh)-PEG4000 is methyl methacrylate, and MAh is maleic anhydride, P (MMA-MAh)
It is the copolymer of methyl methacrylate and maleic anhydride, PEG6000 is the polyethylene glycol that molecular weight is 6000；
(2) 7 part of ten dihydroxystearic acid is added in first mixed liquid, is heated to 45 DEG C of reaction 9min under nitrogen protection；
(3) polyacrylate -2- cross-linked polymers are obtained after being dried with deionized water rinsing.
Detection obtains in performance, and the present embodiment has good water resistance and adhesive force, and water absorption rate is less than 3.3%；For
The detection of traditional performance, it is as follows：It is uniform with common coating method, as much as possible coating；It it is 32 DEG C in temperature, humidity is
50%, seawater immersion is Sanya Yalongwan holiday resort seawater；All washings are general water-washing method, and simulation respectively is had a bath, gone
Hand is dirty, does housework, swims, and for the suds used for general alkaline soap water, washing powder is regular powder, and this experiment uses
Carve board.
After drying 20 minutes, under normal temperature washing state, film still comes off without discoloration, nothing after 70 minutes；In 40 DEG C of temperature
Under water washing state, film still comes off without discoloration, nothing after 75 minutes；Under suds washing state, after 35 minutes film still without
Discoloration, nothing come off；Under washing powder washing state, film is still unchanged after 65 minutes, and nothing comes off；Under seawater soaking state,
Film still comes off without discoloration, nothing after 85 minutes；Under accidental collision impact, film, which has, to come off.
Embodiment 12：
With embodiment nine except that containing 3 parts of the 4th composite regulator in nail polish glue.Wherein, the 4th compound tune
Section agent is made according to the 4th composite regulator formula 3.
The preparation method of second elastic plastic is：It is 23% polyvinyl alcohol water solution and 25 parts by 2 parts of mass concentrations
The 17wt% aqueous polyurethane aqueous solution is heated up to 70 DEG C, is cooled to the acrylate of 12 parts of addition after 40 DEG C, then adds 0.2
Part lithium hydroxide and be warming up to 105 DEG C, add 7 parts of sclerotin albumen, 7 parts of rosin, 3 parts of eugenol, and be incubated
Reaction is cooled to 50 DEG C after 4 hours, then adds 7 parts of bamboo charcoal micropowder, 6 parts of negative ion powder and 12 parts of octyl phenol polyoxy second
Alkene ether, stir 1.2 hours, cooling, second elastic plastic is made.
The preparation method of this kind of nail polish glue is：Addition adds following components successively in order,
11,14- bis- dislike -2,9- diaza heptadecane -16- olefin(e) acids -4,4,6,16- tetramethyl -10,15- dioxo -2-
[(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
Compound of formula I；
Acrylate quasi-oligomer；
1- hydroxycyclohexyl phenyl ketones；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyl)；
Hydroxyethyl methacrylate；
Triethanolamine；
Laureth -21；
Mica；
High-speed stirred is well mixed after the mixing of above composition, adds all the second composite regulator stirring 12min,
Then all first composite regulators are added to continue to stir 5min；Then all mediation glue stirring 6min are added, are connect
Addition, all the 4th composite regulator continues to stir 3min；All triplex conditioning agents are eventually adding to continue to stir
2min is mixed, obtains finished product.
Wherein, the preparation method of the polyacrylate -2- cross-linked polymers in mediation glue is：
(1) prepared polymer P (MMA-MAh)-PEG600030-40 parts, 50 parts of regulation liquid form just mixed liquid by weight；
It is the carbonic acid third for including the sodium perchlorate that concentration is 0.6mol/L and the N- butyl benzimidazoles that concentration is 0.4mol/L to adjust liquid
Alkene ester solution；MMA in polymer P (MMA-MAh)-PEG4000 is methyl methacrylate, and MAh is maleic anhydride, P (MMA-
MAh) be methyl methacrylate and maleic anhydride copolymer, PEG6000 be molecular weight be 6000 polyethylene glycol；
(2) 5 part of ten dihydroxystearic acid is added in first mixed liquid, is heated to 35 DEG C of reaction 6min under nitrogen protection；
(3) polyacrylate -2- cross-linked polymers are obtained after being dried with deionized water rinsing.
Detection obtains in performance, and the present embodiment has good water resistance and adhesive force, and water absorption rate is less than 3.1%；For
The detection of traditional performance, it is as follows：It is uniform with common coating method, as much as possible coating；It it is 32 DEG C in temperature, humidity is
50%, seawater immersion is Sanya Yalongwan holiday resort seawater；All washings are general water-washing method, and simulation respectively is had a bath, gone
Hand is dirty, does housework, swims, and for the suds used for general alkaline soap water, washing powder is regular powder, and this experiment uses
Carve board.
After drying 20 minutes, under normal temperature washing state, film still comes off without discoloration, nothing after 62 minutes；In 40 DEG C of temperature
Under water washing state, film still comes off without discoloration, nothing after 68 minutes；Under suds washing state, after 33 minutes film still without
Discoloration, nothing come off；Under washing powder washing state, film is still unchanged after 61 minutes, and nothing comes off；Under seawater soaking state,
Film still comes off without discoloration, nothing after 78 minutes；Under accidental collision impact, film, which has, to come off.
Embodiment 13：
With embodiment ten except that the first composite regulator is made according to the first composite regulator formula 1；Second
Composite regulator is made according to the second composite regulator formula 2；Triplex conditioning agent is made according to triplex conditioner formulations 3
Into；4th composite regulator is made according to the 4th composite regulator formula 1.
Embodiment 14：
With embodiment 11 except that the first composite regulator is made according to the first composite regulator formula 1；The
Two composite regulators are made according to the second composite regulator formula 3；Triplex conditioning agent is according to triplex conditioner formulations 2
It is made；4th composite regulator is made according to the 4th composite regulator formula 2.
Embodiment 15：
With embodiment 12 except that the first composite regulator is made according to the first composite regulator formula 2；The
Two composite regulators are made according to the second composite regulator formula 1；Triplex conditioning agent is according to triplex conditioner formulations 3
It is made；4th composite regulator is made according to the 4th composite regulator formula 3.
Activity experiment：
1st, compound of formula I activity experiment
Bacterium (Trichophyton rubrum, trichophyton gypseum and Epidermophvton trichophyta) is suspended in MH culture mediums, disperseed
Concentration is about 105cfu.mL-1, bacterium solution is added on 96 orifice plates and (adds the μ L of bacterium solution 100 per hole), using culture medium as blank control,
Tested material is replaced as negative control using DMSO, with Itraconazole (Xian-Janssen Pharmaceutical Ltd.) for positive control.By Formulas I
Compound is dissolved in DMSO is made into 800,400,200,100,50,25 μ g.mL respectively-1Solution is (for MIC5oLess than 5 μ gmL-1
, when carrying out step experiment, the concentration gradient of preparation is 50,25,12.5,6.25,3.1,1.5 μ gmL-1), with every μ L of hole 11
Amount be added on 96 orifice plates【The ultimate density of decoction is respectively 80,40,20,10,5,2.5 μ gmL-1(be 5 for the latter,
2.5th, 1.25,0.63,0.31 and 0.15 μ gmL-1)】, each concentration gradient does four parallel laboratory tests.96 orifice plates are put into 37 DEG C
Incubator in cultivate 24h, PBSs of the 25 μ L per mL MTT containing 4mg is then added per hole, then 4h is cultivated under similarity condition, often
Hole adds 100 μ LSDS lysates (95mL tri-distilled water+10gSDS+5mL isopropanol+0.1mL concentrated hydrochloric acids) and cultivates 12h afterwards.With enzyme mark
Instrument determines OD values under 570nm, and percent inhibition is calculated as follows：
The height of activity is with semi-inhibit rate MIC50To represent, MIC50It is smaller, compound activity it is higher, as a result for：Formulas I
Compound is to Trichophyton rubrum, trichophyton gypseum and Epidermophvton trichophyta semi-inhibit rate MIC50Respectively 0.63,0.60 and
0.82；Itraconazole is to Trichophyton rubrum, trichophyton gypseum and Epidermophvton trichophyta semi-inhibit rate MIC50Respectively 0.63,
0.70 and 0.65.
2nd, agent activity is tested：
Using preparation described in embodiment 1-5, the activity experiment being discussed below：
About 0.5mm thickness is cut from the corner of ox horn, the small pieces of 1.5 × 3cm sizes are simultaneously handled half with embodiment 1-5 preparations
Side, once a day, continuous five days.Then the piece is fixed on to about 0.5cm above the aqueous agar surface of a moisture chamber
On metal column, treated is half side face-down.The whole side of ox horn upward is inoculated with small point of trichophyton mentagrophytes in dots
Raw spore suspension.Then, bacterium colony form is stored 10 days at 28 DEG C.
Allergenic is prevented 5 times using the pretreatment of 1-5 of embodiment of the present invention preparation at half of the back side of ox horn
Son germinates in whole top surface.Even after 90 days, still vaccination can not be observed in whole top surface under the microscope.Therefore,
Embodiment 1-5 preparations containing compound of formula I can effectively pre- anti-fungal growth.
According to the method described above, control experiment is carried out, distinguishes and compound of formula I is all being free of in preparation described in embodiment 1-5,
Fungi has a small number of growing points on treated ox horn side, but the good growth of fungi is observed in another half.
The blank that invention formulation is handled is not used after inoculation, and fungi fully grows on ox horn surface.
When the nail polish glue of the present invention is coated on nail, health environment-friendly, have no irritating odor, it is only necessary to using LED light
Solidify illumination 1-2 minutes be curable film-forming, can rapid draing, dry after formed light film coating, stable performance；It is intended to change
When becoming color, it is only necessary to torn after nail tip stripping, it is very easy to use safe and healthy；Reach effect week thrown week and changed
Fruit.Flood easily divests during nail polish glue removal of the present invention, has nail maintenance effect, for fragile nail there is enhancing protection to make
With, can improve comprehensively nail layering easy fracture problem.The Formulas I chemical combination extracted from ginkgo leaf is with the addition of in inventive formulation
Thing, it can effectively prevent the generation of nail fungi.
Claims (10)
1. a kind of 4D nail polish glue, it is characterised in that include the component of following parts by weight：
The 11,14- bis- of 38-45 parts -- 2,9- diaza heptadecane -16- olefin(e) acid -4,4,6,16- tetramethyl -10,15- dioxies
Generation -2- [(2- methyl isophthalic acids-oxo -2- acrylic) oxo] ethyl ester；
The compound of formula I of 0.02-0.04 parts；
The acrylate quasi-oligomer of 25-29 parts；
The 1- hydroxycyclohexyl phenyl ketones of 2.4-2.9 parts；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyls) of 2.5-3.1 parts；
The hydroxyethyl methacrylate of 11-13 parts；
1.1-1.4 the triethanolamine of part；
The laureth -21 of 0.7-0.8 parts；
1.5-2.8 part micas；
The compound of formula I is shown below：
2. nail polish glue according to claim 1, it is characterised in that also red containing the red 0.9-1.6 parts of C117200, C15850
0.5-1 parts, the black 2.8-3.6 parts of C177499, C177492 Huang 0.15-0.22 parts, CN15985 Huang 0.14-0.21 parts, C177510
The colouring agent of one or more of blue 1.03-1.35 parts or the white 2.15-2.65 parts of C177891.
3. nail polish glue according to claim 1, it is characterised in that also containing mediation glue 6-8 parts, the mediation glue is by following
The component composition of parts by weight：Polyacrylate -2- cross-linked polymer 42-48 parts；Benzophenone 7-10 parts；EMA
23-28 parts；Dimethyl silicone polymer 8-16 parts；Trimethylolpropane trimethacrylate 10-15 parts.
4. nail polish glue according to claim 3, it is characterised in that contain first composite regulator 7-9 parts in the nail polish glue
With second composite regulator 8-10 parts；First composite regulator includes in mass ratio 1：3-4：Polyglycereol-the 2- of 1-2 compositions
Three isostearates, glycerine and AVC mixture；And the second compound regulation
Agent includes in mass ratio 1：2-4:Two isooctadecanol malic acid fat, silylated silica and the butylmethoxy two of 1-3 compositions
Benzoyl methane mixture.
5. nail polish glue according to claim 4, it is characterised in that contain triplex conditioning agent 4-6 in the nail polish glue
Part；The triplex conditioning agent includes in mass ratio 1:0.5-0.8:The deacetylation of 1.3-1.7 compositions is in the de- of 70-80%
Acetyl degree chitosan, molecular weight are the oligosaccharide of 1800-2000 dalton and DPnB mixture.
6. nail polish glue according to claim 5, it is characterised in that the preparation method of the deacetylation chitosan is：Will
Chitin 135-145 DEG C of heating 1-2h in mass concentration 40-50% alkali lye, is made deacetylation 70-80%, molecule
Measure as the chitosan of 20000-35000 dalton.
7. nail polish glue according to claim 6, it is characterised in that the preparation of the polyacrylate -2- cross-linked polymers
Method is：(1) prepared polymer P (MMA-MAh)-PEG6000 30-40 parts, regulation liquid 40-60 parts form and just mixed by weight
Liquid；Described regulation liquid is to include the sodium perchlorate that concentration is 0.4-0.7mol/L and the N- butyl that concentration is 0.3-0.8mol/L
The carbonic allyl ester solution of benzimidazole；MMA in described polymer P (MMA-MAh)-PEG4000 is methyl methacrylate
Ester, MAh are maleic anhydrides, and P (MMA-MAh) is the copolymer of methyl methacrylate and maleic anhydride, and PEG6000 is molecular weight
For 6000 polyethylene glycol；(2) dihydroxystearic acid of 2-7 parts ten is added in the just mixed liquid, be heated under nitrogen protection
30-45 DEG C of reaction 5-9min；(3) polyacrylate -2- cross-linked polymers are obtained after being dried with deionized water rinsing.
8. nail polish glue according to claim 7, it is characterised in that contain the 4th composite regulator 1-4 in the nail polish glue
Part；
4th composite regulator is made up of the raw material of following parts by weight：Cetanol caprylate 28-33 parts, glutaric acid 15-
18 parts, butantriol 8-10 parts, Zinc Oxide 5-7 parts, magnesia 3-5 parts, neoprene 18-23 parts, elastic plastic 70-95 parts, softening
Oily 2-3 parts, dimethyl carbonate 15-20 parts and ethylbenzene 22-28 parts；The elastic plastic is included by weight 1:The first of 2-5 mixing
Elastic plastic and the second elastic plastic；The acrylic acid tree that the solids content that first elastic plastic includes 15-30 part weight is 60-75%
Fat liquor, 12-15 parts aqueous polyurethane, the acrylic resin powder of 5-8 part weight, the solids content of 2-6 part weight are 20-
35% EVA emulsions and the chlorinated polypropylene of 1-4 part weight；The preparation method of second elastic plastic is：By 1-5 part quality
Concentration is that 20-25% polyvinyl alcohol water solution and the 20-30 parts 15-20wt% aqueous polyurethane aqueous solution are heated up to 60-80
DEG C, the acrylate that 10-15 parts are added after 30-50 DEG C is cooled to, the lithium hydroxide of 0.1-0.2 parts is then added and is warming up to
100-110 DEG C, add the sclerotin albumen of 5-8 parts, the rosin of 6-9 parts, the eugenol of 2-4 parts, and insulation reaction 3-5 hours
After be cooled to 45-55 DEG C, then add 6-8 parts bamboo charcoal micropowder, the negative ion powder of 2-7 parts and the octyl phenol polyoxy of 10-13 parts
Vinethene, stir 1-1.5 hours, cooling, second elastic plastic is made.
9. nail polish glue according to claim 8, it is characterised in that the preparation method of the nail polish glue is：Add successively in order
Add the following substances of corresponding parts by weight
11,14- bis- dislikes -2,9- diaza heptadecane -16- olefin(e) acid -4,4,6,16- tetramethyl -10,15- dioxos -2- [(2- first
Base -1- oxo -2- acrylic) oxo] ethyl ester；
Compound of formula I；
Acrylate quasi-oligomer；
1- hydroxycyclohexyl phenyl ketones；
Double phenyl phosphine oxides (2,4,6- trimethylbenzoyls)；
Hydroxyethyl methacrylate；
Triethanolamine；
Laureth -21；
Mica；
High-speed stirred is well mixed after the mixing of above composition, adds all the second composite regulator stirring 10-15min,
Then all first composite regulators are added to continue to stir 3-6min；Then all mediation glue stirring 5- are added
9min, it is subsequently added into all the 4th composite regulators and continues to stir 2-5min；All triplex are eventually adding to adjust
Section agent continues to stir 1-4min, obtains finished product.
10. the application method of any 4D nail polish glue of claim 1-9, it is characterised in that comprise the steps：
(1) nail surface is cleaned；
(2) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiate 60 seconds-
120 seconds；
(3) on nail surface it is frivolous, be evenly coated with one layer of nail polish glue；Nail surface is irradiated 60 seconds -120 in LED nail lamps
Second；This step is according to demand or hobby can repeat 1-2 times；
(4) one layer of nail polish glue of frivolous, uniform smearing on nail surface；Using LED nail lamps to nail surface irradiate 60 seconds-
120 seconds.
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| CN106667834A (en) * | 2016-12-09 | 2017-05-17 | 陈忠燕 | Environment-friendly watermelon seed quick-dry nail-care oil |
| CN109381374A (en) * | 2017-09-26 | 2019-02-26 | 深圳恒尚美妆贸易有限公司 | A kind of nail polish glue and its preparation and application method |
| CN108852866A (en) * | 2018-07-20 | 2018-11-23 | 广州市精合致新材料科技有限公司 | One kind is from ordor removing nail polish glue and preparation method thereof |
| CN112716821A (en) * | 2020-12-23 | 2021-04-30 | 金华市科维思日化有限公司 | Low-odor UV crystal liquid and curing method thereof |
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| US20030064044A1 (en) * | 2001-04-16 | 2003-04-03 | Chen Shih-Ruey T. | Cosmetic compositions containing water-soluble polymer complexes |
| CN102228411A (en) * | 2011-06-23 | 2011-11-02 | 谭卓华 | Two-in-one water-soluble nail painting and protecting membrane solution |
| CN104758195A (en) * | 2014-01-06 | 2015-07-08 | 万华化学（广东）有限公司 | Waterborne nail polish based on aqueous polyurethane dispersion |
| CN104800125A (en) * | 2015-05-04 | 2015-07-29 | 上海零玖科技有限公司 | Nail polish and preparation method thereof |
| US20150297496A1 (en) * | 2012-11-05 | 2015-10-22 | Hercules Incorporated | Personal care composition for a keratin substrate comprising conditioning and/or styling polymer |
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Patent Citations (5)
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|---|---|---|---|---|
| US20030064044A1 (en) * | 2001-04-16 | 2003-04-03 | Chen Shih-Ruey T. | Cosmetic compositions containing water-soluble polymer complexes |
| CN102228411A (en) * | 2011-06-23 | 2011-11-02 | 谭卓华 | Two-in-one water-soluble nail painting and protecting membrane solution |
| US20150297496A1 (en) * | 2012-11-05 | 2015-10-22 | Hercules Incorporated | Personal care composition for a keratin substrate comprising conditioning and/or styling polymer |
| CN104758195A (en) * | 2014-01-06 | 2015-07-08 | 万华化学（广东）有限公司 | Waterborne nail polish based on aqueous polyurethane dispersion |
| CN104800125A (en) * | 2015-05-04 | 2015-07-29 | 上海零玖科技有限公司 | Nail polish and preparation method thereof |
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