CN1052163C - Composition for treating gallstones and kidney stones - Google Patents
Composition for treating gallstones and kidney stones Download PDFInfo
- Publication number
- CN1052163C CN1052163C CN96109863A CN96109863A CN1052163C CN 1052163 C CN1052163 C CN 1052163C CN 96109863 A CN96109863 A CN 96109863A CN 96109863 A CN96109863 A CN 96109863A CN 1052163 C CN1052163 C CN 1052163C
- Authority
- CN
- China
- Prior art keywords
- radix
- parts
- grams
- sus domestica
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 201000001883 cholelithiasis Diseases 0.000 title claims abstract description 10
- 206010029148 Nephrolithiasis Diseases 0.000 title claims abstract description 6
- 208000000913 Kidney Calculi Diseases 0.000 title claims description 5
- 208000001130 gallstones Diseases 0.000 title claims description 5
- 239000000203 mixture Substances 0.000 title abstract description 5
- 210000003038 endothelium Anatomy 0.000 claims abstract description 12
- 241001071795 Gentiana Species 0.000 claims abstract description 3
- 239000003814 drug Substances 0.000 claims description 33
- 241000282894 Sus scrofa domesticus Species 0.000 claims description 29
- 229940079593 drug Drugs 0.000 claims description 18
- 239000006187 pill Substances 0.000 claims description 10
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 9
- 239000008194 pharmaceutical composition Substances 0.000 claims description 9
- 235000014375 Curcuma Nutrition 0.000 claims description 2
- 244000164439 Curcuma angustifolia Species 0.000 claims description 2
- 241000612166 Lysimachia Species 0.000 claims description 2
- 241001529553 Scoparia <angiosperm> Species 0.000 claims description 2
- 241000207929 Scutellaria Species 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims description 2
- 239000004575 stone Substances 0.000 abstract description 5
- 230000006870 function Effects 0.000 abstract description 4
- 206010004637 Bile duct stone Diseases 0.000 abstract description 3
- 201000009331 Choledocholithiasis Diseases 0.000 abstract description 3
- 210000000941 bile Anatomy 0.000 abstract description 3
- 201000001352 cholecystitis Diseases 0.000 abstract description 3
- 201000010099 disease Diseases 0.000 abstract description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 3
- 210000004185 liver Anatomy 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 abstract description 2
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 abstract 1
- 235000003097 Artemisia absinthium Nutrition 0.000 abstract 1
- 240000001851 Artemisia dracunculus Species 0.000 abstract 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 235000015221 Bupleurum rotundifolium Nutrition 0.000 abstract 1
- 244000236521 Bupleurum rotundifolium Species 0.000 abstract 1
- 241000050051 Chelone glabra Species 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 244000163122 Curcuma domestica Species 0.000 abstract 1
- 235000003392 Curcuma domestica Nutrition 0.000 abstract 1
- 241000522190 Desmodium Species 0.000 abstract 1
- 240000000233 Melia azedarach Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 abstract 1
- 244000153955 Reynoutria sachalinensis Species 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 239000001138 artemisia absinthium Substances 0.000 abstract 1
- 235000003373 curcuma longa Nutrition 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- 235000013976 turmeric Nutrition 0.000 abstract 1
- 239000006071 cream Substances 0.000 description 13
- 239000000843 powder Substances 0.000 description 13
- 230000000694 effects Effects 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 239000000796 flavoring agent Substances 0.000 description 6
- 235000019634 flavors Nutrition 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 238000007670 refining Methods 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 210000000232 gallbladder Anatomy 0.000 description 3
- 230000002485 urinary effect Effects 0.000 description 3
- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 description 3
- 229960001661 ursodiol Drugs 0.000 description 3
- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 229960001091 chenodeoxycholic acid Drugs 0.000 description 2
- RUDATBOHQWOJDD-BSWAIDMHSA-N chenodeoxycholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-BSWAIDMHSA-N 0.000 description 2
- 229960003964 deoxycholic acid Drugs 0.000 description 2
- KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 description 2
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 206010007027 Calculus urinary Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010020524 Hydronephrosis Diseases 0.000 description 1
- 206010023129 Jaundice cholestatic Diseases 0.000 description 1
- 201000005267 Obstructive Jaundice Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 208000009911 Urinary Calculi Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 239000008845 cholagoga Substances 0.000 description 1
- 229940124571 cholagogue Drugs 0.000 description 1
- 210000001953 common bile duct Anatomy 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a composition for treating cholelithiasis and nephrolithiasis, which is prepared from desmodium, bitter orange, costustoot, rhubarb, gentian, endothelium corneum gigeriae galli, giant knotweed rhizome, pig bile, white paeony root, Chinese thorowax root, virgate wormwood herb, turmeric root-tuber, szechwan chinaberry fruit and baical skullcap root, has multiple functions of soothing liver and regulating qi, removing and expelling stone, benefiting gall and diminishing inflammation, clearing heat and eliminating dampness, dissolving stone and the like, and can be used for treating diseases such as hepatolithiasis, cholelithiasis, choledocholithiasis, cholecystitis and the like.
Description
The present invention relates to a kind of Chinese patent medicine for the treatment of gallstones and kidney stones, the Chinese medicine that is prepared from for the main pharmacodynamics composition with the Chinese herbal medicine particularly, can be used for treating diseases such as hepatic calculus, cholelithiasis, choledocholithiasis, cholecystitis, urinary system calculus, belong to field of traditional Chinese.
Clinically, calculus is that liver and bile stone and urinary system calculus are seen more with digestion.For the Iithiasic treatment of this class, traditional Therapeutic Method is a surgical calculus removing, and the patient is difficult for accepting because of painful, financial burden weigh; And the postoperative recurrence rate is higher, even some patient operation for the second time of being compelled to do.The another kind of method that adopts is large-scale lithotripsy in treatment at present, and expense is higher, and not necessarily can both be broken, can not arrange the broken back of part calculus, even cause that tube chamber stops up, and causes whole body xanthochromia or hydronephrosis, influence the function of liver, gallbladder or kidney, give to continue to treat and bring difficulty.The common chemical medicine has chenodeoxycholic acid and male deoxycholic acid etc., according to external; Moth deoxycholic acid safety lithodialysis rate is 13.6%, and effectively the lithodialysis rate is 40.5%, and the lithodialysis rate of ursodesoxycholic acid is 25.8%, and the effective lithodialysis rate of domestic report is 39.5%, and its side effect is more, and the patient who is not suitable for the women of child-bearing age and hepatic and kidney function obstacle takes.In addition, ursodesoxycholic acid can make the calculus calcification, is unfavorable for lithodialysis.Practical application proves: chenodeoxycholic acid and ursodesoxycholic acid medication cycle are long, and lithodialysis blood fat reducing lithagogue effect is poor.At present, also carried out some researchs aspect traditional Chinese medicine lithagogue, and there have the urinary calculus removing Chinese patent medicine to be applied to be clinical, still, if these drug mains based on calculus, carry out lithagogue treatment for the cholelithiasis of major diameter calculus, its effect is undesirable, even does not have effect.
The object of the invention provides a kind of pharmaceutical composition made from Chinese herbal medicine with calculus, fossilization.
The composition of pharmaceutical composition of the present invention is counted by weight ratio:
Herba Lysimachiae 40-70 part
Fructus Aurantii 10-30 part
Radix Aucklandiae 10-30 part
Radix Et Rhizoma Rhei 20-40 part
Radix Gentianae 10-30 part
Endothelium Corneum Gigeriae Galli 20-40 part
Rhizoma Polygoni Cuspidati 40-60 part
Fel Sus domestica 5-25 part
Radix Paeoniae Alba 15-35 part
Radix Bupleuri 20-40 part
Herba Artemisiae Scopariae 15-35 part
Radix Curcumae 15-35 part
Fructus Toosendan 20-40 part
Radix Scutellariae 10-30 part.
The preferred weight proportioning of pharmaceutical composition of the present invention is:
Herba Lysimachiae 50-65 part
Fructus Aurantii 15-25 part
Radix Aucklandiae 15-25 part
Radix Et Rhizoma Rhei 25-35 part
Radix Gentianae 15-25 part
Endothelium Corneum Gigeriae Galli 25-30 part
Rhizoma Polygoni Cuspidati 45-55 part
Fel Sus domestica 10-20 part
Radix Paeoniae Alba 20-30 part
Radix Bupleuri 25-35 part
Herba Artemisiae Scopariae 20-30 part
Radix Curcumae 20-30 part
Fructus Toosendan 25-35 part
Radix Scutellariae 15-25 part.
The optimum weight proportioning of medicine of the present invention is:
60 parts of Herba Lysimachiaes
20 parts of Fructus Aurantiis
20 parts of the Radix Aucklandiae
30 parts of Radix Et Rhizoma Rhei
20 parts of Radix Gentianaes
30 parts of Endothelium Corneum Gigeriae Galli
50 parts of Rhizoma Polygoni Cuspidati
15 parts of Fel Sus domestica
25 parts of the Radix Paeoniae Albas
30 parts of Radix Bupleuri
25 parts of Herba Artemisiae Scopariaes
25 parts of Radix Curcumaes
30 parts of Fructus Toosendans
20 parts of Radix Scutellariaes.
Pharmaceutical composition of the present invention can be prepared into common drug dosage form clinically, for example, and pill, tablet, unguentum, capsule, impact, oral liquid etc.
The pill preparation method of medicine of the present invention is:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, and with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with refining good Mel 600 grams, make honeyed pill at last with the medicine mixing.
Medicine of the present invention has the good curing effect to gallstones and kidney stones.Have multiple functions such as depressed liver-energy dispersing and QI regulating, dissovling and discharging calculus, cholagogue and eliminating inflammation, clearing away heat and eliminating dampness, calculus softening and dissolving.Medicine of the present invention is particularly suitable for being used with the another kind of external used medicine of inventor's development, by oral pills, allomeric function is strengthened, and strengthens the gallbladder wriggling, promotes bile secretion to drain, and further promotes calculus; By the cooperation of inside and outside medicine, can make lax, the expansion of stone location tube chamber height, be retracted again then.The repeated multiple times wriggling can make the calculus that becomes shortcake layer by layer come off like this, and the broken end that comes off can be got rid of external immediately.
Following clinical observation material can prove absolutely the good result of medicine of the present invention.
Clinical observation report
1. physical data:
50 routine patients, male's 24 examples, women's 26 examples; The oldest person 70 years old, surplus the elder of reckling 20 years old, the course of disease reaches 20 year, the shortest person 1 month.
1) the calculus size and the form of observing under the B ultrasonic;
Microlith (diameter is person below 0.5 centimetre) 9 examples, medium calculus (calculus diameter more than or equal to 0.5 centimetre, and be less than or equal to 1.5 centimetres of persons, 25 examples), maximum size (diameter is greater than 15 centimetres of persons) 8 examples, muddy stone 3 examples, multiple calculus 5 examples that are full of.
2) calculus size and the form that feces is drawn out washed to draw in the treatment back:
Maximum 0.7 centimetre, minimum as silt sample and grain of rice shape; The calculus as hard as flint that has hits and not broken; The calculus short texture that has is the agglomerate sample.Form has circle, oval, not shaping, has the sense of wax sample individually.3) complication:
Concurrent cholecystitis person 20 examples, atrophy of gallbladder 2 examples, obstructive jaundice 1 example.
4) various calculus types:
Calculus of intrahepatic duct 3 examples, cholelithiasis 32 examples, choledocholithiasis 5 examples, urinary system calculus 10 examples.
5) tcm syndrome differentiation and typing:
Divide type of depression of QI and damp-heat type two big classes.
2. Therapeutic Method:
The fossil lithagogue pill is for oral administration, is mainly used in the damp-heat type calculi therapy; The fossil lithagogue pill cooperates fossil cream to be used for the treatment of type of depression of QI calculus.
3 criterions of therapeutical effect:
1) recovery from illness:
Through treatment, draw out calculus in the stool, the symptom and sign complete obiteration; The B ultrasonic check confirms the calculus emptying, and common bile duct is clear, no abnormal sound shadow.
2) produce effects:
Symptom and sign obviously alleviates or disappears, and confirms to discharge 12 above calculus persons through the B ultrasonic check.
3) effective: symptom and sign takes a turn for the better or basic the disappearance, confirms that through the B ultrasonic check calculus quantity reduces or obviously dwindles.
4) invalid:
Through 1 course of therapy (30 days), symptom and sign does not have obvious improvement, and B ultrasonic check calculus as before.
4. result:
Among the 50 routine patients, 28 examples of fully recovering, produce effects 10 examples, effective 8 examples do not have 4 examples of preparation, and total effective rate is 80%.
Embodiment 1
Prescription:
Herba Lysimachiae 40 grams
Fructus Aurantii 10 grams
The Radix Aucklandiae 10 grams
Radix Et Rhizoma Rhei 20 grams
Radix Gentianae 10 grams
Endothelium Corneum Gigeriae Galli 20 grams
Rhizoma Polygoni Cuspidati 40 grams
Fel Sus domestica 5 grams
The Radix Paeoniae Alba 15 grams
Radix Bupleuri 20 grams
Herba Artemisiae Scopariae 15 grams
Radix Curcumae 15 grams
Fructus Toosendan 20 grams
Radix Scutellariae 10 grams.
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, and with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with refining good Mel 400 grams, make honeyed pill at last with the medicine mixing.
Embodiment 2
Herba Lysimachiae 70 grams
Fructus Aurantii 30 grams
The Radix Aucklandiae 30 grams
Radix Et Rhizoma Rhei 40 grams
Radix Gentianae 30 grams
Endothelium Corneum Gigeriae Galli 40 grams
Rhizoma Polygoni Cuspidati 60 grams
Fel Sus domestica 25 grams
The Radix Paeoniae Alba 35 grams
Radix Bupleuri 40 grams
Herba Artemisiae Scopariae 35 grams
Radix Curcumae 35 grams
Fructus Toosendan 40 grams
Radix Scutellariae 30 grams.
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, and with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with refining good Mel 700 grams, make honeyed pill at last with the medicine mixing.
Embodiment 3
Prescription:
Herba Lysimachiae 50 grams
Fructus Aurantii 15 grams
The Radix Aucklandiae 15 grams
Radix Et Rhizoma Rhei 25 grams
Radix Gentianae 15 grams
Endothelium Corneum Gigeriae Galli 25 grams
Rhizoma Polygoni Cuspidati 45 gram Fel Sus domestica 10 grams
The Radix Paeoniae Alba 20 grams
Radix Bupleuri 25 grams
Herba Artemisiae Scopariae 20 grams
Radix Curcumae 20 grams
Fructus Toosendan 25 grams
Radix Scutellariae 15 grams.
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with alcohol granulation, add magnesium stearate, granulate is used the tablet machine tabletting, makes tablet.
Embodiment 4
Herba Lysimachiae 65 grams
Fructus Aurantii 25 grams
The Radix Aucklandiae 25 grams
Radix Et Rhizoma Rhei 35 grams
Radix Gentianae 25 grams
Endothelium Corneum Gigeriae Galli 30 grams
Rhizoma Polygoni Cuspidati 55 grams
Fel Sus domestica 20 grams
The Radix Paeoniae Alba 30 grams
Radix Bupleuri 35 grams
Herba Artemisiae Scopariae 30 grams
Radix Curcumae 30 grams
Fructus Toosendan 35 grams
Radix Scutellariae 25 grams.
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, oven dry is ground into fine powder, after again other several drugs component being mixed, be ground into fine powder together,, cross 100 mesh sieves with above-mentioned Fel Sus domestica cream fine powder mix homogeneously, encapsulated, make capsule.
Embodiment 5
Prescription:
Herba Lysimachiae 60 grams
Fructus Aurantii 20 grams
The Radix Aucklandiae 20 grams
Radix Et Rhizoma Rhei 30 grams
Radix Gentianae 20 grams
Endothelium Corneum Gigeriae Galli 30 grams
Rhizoma Polygoni Cuspidati 50 grams
Fel Sus domestica 15 grams
The Radix Paeoniae Alba 25 grams
Radix Bupleuri 30 grams
Herba Artemisiae Scopariae 25 grams
Radix Curcumae 25 grams
Fructus Toosendan 30 grams
Radix Scutellariae 20 grams.
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, and with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with refining good Mel 700 grams, make honeyed pill at last with the medicine mixing.
Claims (5)
1. pharmaceutical composition for the treatment of gallstones and kidney stones is characterized in that being made by the component of following weight ratio:
Herba Lysimachiae 40-70 part
Fructus Aurantii 10-30 part
Radix Aucklandiae 10-30 part
Radix Et Rhizoma Rhei 20-40 part
Radix Gentianae 10-30 part
Endothelium Corneum Gigeriae Galli 20-40 part
Rhizoma Polygoni Cuspidati 40-60 part
Fel Sus domestica 5-25 part
Radix Paeoniae Alba 15-35 part
Radix Bupleuri 20-40 part
Herba Artemisiae Scopariae 15-35 part
Radix Curcumae 15-35 part
Fructus Toosendan 20-40 part
Radix Scutellariae 10-30 part.
2. according to the pharmaceutical composition of claim 1, it is characterized in that making by the component of following weight ratio:
Herba Lysimachiae 50-65 part
Fructus Aurantii 15-25 part
Radix Aucklandiae 15-25 part
Radix Et Rhizoma Rhei 25-35 part
Radix Gentianae 15-25 part
Endothelium Corneum Gigeriae Galli 25-30 part
Rhizoma Polygoni Cuspidati 45-55 part
Fel Sus domestica 10-20 part
Radix Paeoniae Alba 20-30 part
Radix Bupleuri 25-35 part
Herba Artemisiae Scopariae 20-30 part
Radix Curcumae 20-30 part
Fructus Toosendan 25-35 part
Radix Scutellariae 15-25 part.
3. according to the pharmaceutical composition of claim 2, it is characterized in that making by the component of following weight ratio:
60 parts of Herba Lysimachiaes
20 parts of Fructus Aurantiis
20 parts of the Radix Aucklandiae
30 parts of Radix Et Rhizoma Rhei
20 parts of Radix Gentianaes
30 parts of Endothelium Corneum Gigeriae Galli
50 parts of Rhizoma Polygoni Cuspidati
15 parts of Fel Sus domestica
25 parts of the Radix Paeoniae Albas
30 parts of Radix Bupleuri
25 parts of Herba Artemisiae Scopariaes
25 parts of Radix Curcumaes
30 parts of Fructus Toosendans
20 parts of Radix Scutellariaes.
4. according to the pharmaceutical composition of claim 1 or 2 or 3, it is characterized in that it is any dosage form of acceptable drug clinically.
5. according to the pharmaceutical composition of claim 4, it is characterized in that it is a kind of pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96109863A CN1052163C (en) | 1996-09-24 | 1996-09-24 | Composition for treating gallstones and kidney stones |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96109863A CN1052163C (en) | 1996-09-24 | 1996-09-24 | Composition for treating gallstones and kidney stones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1150041A CN1150041A (en) | 1997-05-21 |
| CN1052163C true CN1052163C (en) | 2000-05-10 |
Family
ID=5120672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96109863A Expired - Fee Related CN1052163C (en) | 1996-09-24 | 1996-09-24 | Composition for treating gallstones and kidney stones |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1052163C (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101224292B (en) * | 2008-02-20 | 2010-08-04 | 肖永雪 | Medicine for treating cholecystitis and preparing method thereof |
| CN101491652B (en) * | 2009-02-24 | 2012-05-09 | 王成果 | A kind of traditional Chinese medicine Paishi pill and preparation method thereof |
| CN102579973B (en) * | 2012-02-02 | 2013-09-18 | 陈中元 | Medicine for treating gall-stone |
| CN103230566B (en) * | 2013-04-19 | 2014-11-26 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof |
| CN104825943A (en) * | 2015-04-22 | 2015-08-12 | 李丽丽 | Cholagogue calculus-expelling traditional Chinese medicine composition for treating cholelithiasis and preparation method thereof |
| CN105031521A (en) * | 2015-06-30 | 2015-11-11 | 赵德欣 | Traditional Chinese medicine composition for treating acute bile duct infection and preparation method thereof |
| CN105597009A (en) * | 2016-01-29 | 2016-05-25 | 粟春生 | Pharmaceutical composition for treating gallstones and preparation method of pharmaceutical composition |
| CN106266130A (en) * | 2016-08-23 | 2017-01-04 | 刘军 | Fast-acting antiphlogistic, ethoxybenzamide Chinese patent medicine preparation |
| CN107823445A (en) * | 2017-10-10 | 2018-03-23 | 季艮 | A kind of Chinese medicine composition for treating gall stone |
| CN107737303A (en) * | 2017-11-17 | 2018-02-27 | 闫柏林 | Stone oral liquid is arranged in stagnation resolvation |
| CN110694032A (en) * | 2019-11-01 | 2020-01-17 | 陕西理工大学 | A kind of traditional Chinese medicine combination for treating gallbladder, kidney and bladder stones and preparation method thereof |
| CN112022999A (en) * | 2020-09-25 | 2020-12-04 | 郭建大 | A kind of traditional Chinese medicine composition for treating hepatolithiasis, its preparation method and use |
| CN118045154A (en) * | 2024-02-21 | 2024-05-17 | 广西中医药大学第一附属医院(广西中医医院) | A Chinese medicine composition for treating cholelithiasis and its preparation method and application |
-
1996
- 1996-09-24 CN CN96109863A patent/CN1052163C/en not_active Expired - Fee Related
Non-Patent Citations (3)
| Title |
|---|
| 《中级医刊》1995,30(10) 1995.10.30 朱宏等，应用金胆片辨证施治举隅 * |
| 《人民军医》1992,(6) 1992.6.30 王志英等，推按运经仪加服药物治疗术后残余结石30例 * |
| 《人民军医》1992,(6) 1992.6.30 王志英等，推按运经仪加服药物治疗术后残余结石30例;《中级医刊》1995,30(10) 1995.10.30 朱宏等，应用金胆片辨证施治举隅 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1150041A (en) | 1997-05-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1116065C (en) | Plaster for treating ostalgia and its preparing process | |
| CN1052163C (en) | Composition for treating gallstones and kidney stones | |
| CN1319569C (en) | Chinese medicine preparation for treating osteoporosis and fracture and preparation process thereof | |
| CN1895628A (en) | Traditional Chinese medicine composition for treating calculus | |
| CN1478508A (en) | A traditional Chinese medicine composition for treating fatty liver and preparation method thereof | |
| CN1218715C (en) | Bone-setting silky fowl ointment for treating osteological diseases and its prepn and application | |
| CN1726991A (en) | Medication of treating by dysenorrhea, irregular menses, weakness after childbirth for women, and preparation method | |
| CN1232279C (en) | Antilipemic Chinese medicine | |
| CN1519017A (en) | A traditional Chinese medicine composition for treating menorrhagia and its preparation and preparation method | |
| CN1305487C (en) | Medicinal composition for treating dysuria due to benign prostatauxe and its preparation method | |
| CN1191849C (en) | Chinese medicine for treating breast disease | |
| CN1562271A (en) | Medication for treating primary disease of purpura haemorhagica and preparation method | |
| CN1190228C (en) | Angong hemostatics | |
| CN100335090C (en) | Medicinal composition for tonifying kidney and eliminating obstruction, and its preparing method | |
| CN1323679C (en) | Medicine for treating enteron diseases | |
| CN1413653A (en) | Chinese drugs for treating cardiovascular and cerebrovascular system disease and its preparation method | |
| CN1651017A (en) | Pharmaceutical composition and preparation method for treating cervical spondylosis | |
| CN1286519C (en) | Medicinal composition for treating cholelithiasis and its preparing method | |
| CN1197611C (en) | Medicine for curing choleithiasis and preparing method thereof | |
| CN1205975C (en) | Chinese medicine for treating prostatitis | |
| CN1820770A (en) | Chinese medicine composition for treating apoplexy and its preparing method | |
| CN1872273A (en) | Medication composition for treating cardiovascular diseases and cerebrovascular disease, and preparation method | |
| CN1225277C (en) | Chinese medicinal composition for treating epilepsy disease and its preparation method | |
| CN1927290A (en) | Ointment for treating naevus and preparing method thereof | |
| CN1824259A (en) | Chinese medicinal preparation for treating woman menstrual pain and its preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |