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CN105169212A - Traditional Chinese medicine composition for treating chronic gastritis - Google Patents

Traditional Chinese medicine composition for treating chronic gastritis Download PDF

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CN105169212A
CN105169212A CN201510727183.1A CN201510727183A CN105169212A CN 105169212 A CN105169212 A CN 105169212A CN 201510727183 A CN201510727183 A CN 201510727183A CN 105169212 A CN105169212 A CN 105169212A
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fructus
herba
rhizoma
semen
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江崇礼
张文海
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Abstract

A traditional Chinese medicine composition for treating chronic gastritis is prepared from mangnolia officinalis, dendrobe, fructus evodiae, semen raphani, perilla stems, endothelium corneum gigeriae galli, pinellia ternata, hooked spikemoss, rhizoma sparganii, rhizoma acori graminei, agastache rugosus, long peppers, barley malt, elecampane, amomum kravanh, corydalis tubers, dried tangerine, inula flowers, semen brassicae, roots of three-nerved spicebush, fiveleaf akebia fruits, fingered citron, semen aesculi, tuber fleeceflower stems, calcined oyster shell, gynostemma pentaphylla, morinda parvifolia, manyprickle acanthopanax roots, semen coicis, lalang grass rhizome, folium callicarpae formosanae, dahurian patrinia herbs and mulberries. Various traditional Chinese medicine raw materials are adopted in the traditional Chinese medicine composition and are reasonably matched, achieve the good synergistic effect by means of the given composition proportion, can promote qi circulation to relieve pains, regulate vital energy to sooth the liver and tonify the spleen to eliminate stagnant, and achieve a remarkable effect in the aspect of treating the chronic gastritis in combination. The traditional Chinese medicine composition is free of adverse effects, and has the advantages of being short in treating course, fast in effect taking and capable of avoiding relapse after cure. The preparing method of the traditional Chinese medicine composition is simple in technology and easy to operate.

Description

A kind of Chinese medicine composition being used for the treatment of chronic gastritis
Technical field
The invention belongs to medical art, relate to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition being used for the treatment of chronic gastritis.
Background technology
Chronic gastritis refers to the various chronic gastric Mucosal inflammatory pathological changes that different pathogeny causes, and be a kind of commonly encountered diseases, its sickness rate ranks first in various gastropathy.Change according to histopathology and pathological changes at the Germ distribution of stomach, in conjunction with the possible cause of disease, chronic gastritis is divided into non-atrophic, atrophic and specific type three major types.The chronic non-atrophic gastritis cause of disease has helicobacter pylori infections (be called for short Hp infect), bile and other alkaline intestinal juice reflux, drink, eat the irritable food such as pungent, take NSAID (non-steroidal anti-inflammatory drug) etc., wherein Hp infects is its topmost reason, and other factors can infect synergism with Hp and increase the weight of gastric mucosa chronic inflammatory disease.Chronic atrophic gastritis is divided into two types.Also known as autoimmune gastritis, based on corpus atrophy, there is autoantibody (comprising parietal cell antibody and intrinsic factor antibody) in the first type, shows as the autoimmune diseasees such as gastric acid secretion minimizing or shortage, pernicious anemia in patient body.The second type is based on gastric antrum atrophy, and minority can develop into gastric cancer, mainly infect with Hp, bile and other alkaline intestinal juice reflux, drink relevant.
Most weight of chronic gastritis symptom and the lesion degree of gastric mucosa are also non-uniform.Most patient often asymptomatic or have degree different indigestion symptom as upper abdomen dull pain, loss of appetite, post-prandial fullness, acid regurgitation etc.The symptoms such as Chronic Atrophic Gastritis Patients can have anemia, becomes thin, glossitis, diarrhoea, person's upper abdominal pain that individuals patients accompanies mucosal erosion is comparatively obvious, and can have the symptoms such as hemorrhage, hematemesis, melena.Symptom is recurrent exerbation usually, and irregularities is suffered from abdominal pain, and pain often to come across in feeding process or after the meal, and majority is positioned at epigastrium, umbilicus week, some patients position are not fixed, and the intermittent dull pain of the lighter or dull pain, severe patient are violent angor.
When patient feels stomach discomfort; usually western medicine can be taken; general different symptoms takes different Western medicine; as taken atropine, probanthine, belladonna mixture etc. during panic attacks; take rabeprazole, lansoprazole, omeprazole etc. when feeling gastric acid, achlorhydria or anacidity person take the digestant such as pancreatin tablets, polyzyme tablets.Taking Western medicine generally can only temporary relief of symptoms, cannot treat disease, and have the side effect such as nausea,vomiting,diarrhea from root, and long-term taking Western medicine also can make body develop immunity to drugs and to drug dependence in addition.
Summary of the invention
The present invention is directed to weak point of the prior art, provide a kind of Chinese medicine composition being used for the treatment of chronic gastritis, this traditional Chinese medicine composition for treating Be very effective, cure rate is high, cheap, has no adverse reaction and toxic and side effects.
Above-mentioned purpose of the present invention is realized by following technical proposals:
Be used for the treatment of a Chinese medicine composition for chronic gastritis, the crude drug of described Chinese medicine composition is made up of Cortex Magnoliae Officinalis, Herba Dendrobii, Fructus Evodiae, Semen Raphani, Caulis Perillae, Endothelium Corneum Gigeriae Galli, the Rhizoma Pinelliae, Herba Selaginellae Uncinatae, Rhizoma Sparganii, Rhizoma Acori Graminei, Herba Pogostemonis, Fructus Piperis Longi, Fructus Hordei Germinatus, Radix Inulae, Fructus Amomi Rotundus, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Flos Inulae, Semen Sinapis Albae, the Radix Linderae, Fructus Akebiae, Fructus Citri Sarcodactylis, Semen Aesculi, Caulis Polygoni Multiflori, Concha Ostreae (calcined), Herb Gynostemmae Pentaphylli, Herba Morindae Parvifoliae, Radix Et Caulis Acanthopanacis Senticosi, Semen Coicis, Rhizoma Imperatae, Folium Callicarpae Formosanae, Herba Patriniae, Fructus Mori.
Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 12-17 part, Herba Dendrobii 7-12 part, Fructus Evodiae 4-9 part, Semen Raphani 15-20 part, Caulis Perillae 10-15 part, Endothelium Corneum Gigeriae Galli 8-12 part, Rhizoma Pinelliae 2-5 part, Herba Selaginellae Uncinatae 3-7 part, Rhizoma Sparganii 11-14 part, Rhizoma Acori Graminei 9-15 part, Herba Pogostemonis 3-6 part, Fructus Piperis Longi 8-13 part, Fructus Hordei Germinatus 3-5 part, Radix Inulae 1-3 part, Fructus Amomi Rotundus 3-6 part, Rhizoma Corydalis 8-13 part, Pericarpium Citri Reticulatae 3-5 part, Flos Inulae 11-15 part, Semen Sinapis Albae 5-10 part, Radix Linderae 2-5 part, Fructus Akebiae 4-9 part, Fructus Citri Sarcodactylis 12-20 part, Semen Aesculi 10-16 part, Caulis Polygoni Multiflori 3-8 part, Concha Ostreae (calcined) 5-12 part, Herb Gynostemmae Pentaphylli 5-10 part, Herba Morindae Parvifoliae 5-10 part, Radix Et Caulis Acanthopanacis Senticosi 13-16 part, Semen Coicis 3-10 part, Rhizoma Imperatae 8-13 part, Folium Callicarpae Formosanae 3-5 part, Herba Patriniae 1-3 part, Fructus Mori 5-10 part.
Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 12 parts, Herba Dendrobii 10 parts, Fructus Evodiae 9 parts, Semen Raphani 15 parts, Caulis Perillae 15 parts, Endothelium Corneum Gigeriae Galli 8 parts, the Rhizoma Pinelliae 5 parts, Herba Selaginellae Uncinatae 3 parts, Rhizoma Sparganii 14 parts, Rhizoma Acori Graminei 9 parts, Herba Pogostemonis 6 parts, Fructus Piperis Longi 8 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 1 part, 6 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 8 parts, Pericarpium Citri Reticulatae 3 parts, Flos Inulae 15 parts, Semen Sinapis Albae 5 parts, the Radix Linderae 3 parts, Fructus Akebiae 5 parts, Fructus Citri Sarcodactylis 12 parts, Semen Aesculi 16 parts, Caulis Polygoni Multiflori 3 parts, Concha Ostreae (calcined) 12 parts, Herb Gynostemmae Pentaphylli 10 parts, Herba Morindae Parvifoliae 5 parts, Radix Et Caulis Acanthopanacis Senticosi 16 parts, Semen Coicis 10 parts, Rhizoma Imperatae 8 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 1 part, Fructus Mori 10 parts.
Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 17 parts, Herba Dendrobii 12 parts, Fructus Evodiae 4 parts, Semen Raphani 20 parts, Caulis Perillae 10 parts, Endothelium Corneum Gigeriae Galli 12 parts, the Rhizoma Pinelliae 2 parts, Herba Selaginellae Uncinatae 7 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 15 parts, Herba Pogostemonis 3 parts, Fructus Piperis Longi 13 parts, Fructus Hordei Germinatus 3 parts, Radix Inulae 3 parts, 4 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 10 parts, Pericarpium Citri Reticulatae 4 parts, Flos Inulae 13 parts, Semen Sinapis Albae 6 parts, the Radix Linderae 4 parts, Fructus Akebiae 8 parts, Fructus Citri Sarcodactylis 20 parts, Semen Aesculi 10 parts, Caulis Polygoni Multiflori 8 parts, Concha Ostreae (calcined) 5 parts, Herb Gynostemmae Pentaphylli 5 parts, Herba Morindae Parvifoliae 10 parts, Radix Et Caulis Acanthopanacis Senticosi 13 parts, Semen Coicis 3 parts, Rhizoma Imperatae 13 parts, Folium Callicarpae Formosanae 3 parts, Herba Patriniae 3 parts, Fructus Mori 5 parts.
Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 13 parts, Herba Dendrobii 7 parts, Fructus Evodiae 5 parts, Semen Raphani 18 parts, Caulis Perillae 11 parts, Endothelium Corneum Gigeriae Galli 9 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 6 parts, Rhizoma Sparganii 12 parts, Rhizoma Acori Graminei 13 parts, Herba Pogostemonis 4 parts, Fructus Piperis Longi 9 parts, Fructus Hordei Germinatus 4 parts, Radix Inulae 2 parts, 5 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 12 parts, Pericarpium Citri Reticulatae 3 parts, Flos Inulae 12 parts, Semen Sinapis Albae 9 parts, the Radix Linderae 4 parts, Fructus Akebiae 7 parts, Fructus Citri Sarcodactylis 13 parts, Semen Aesculi 11 parts, Caulis Polygoni Multiflori 4 parts, Concha Ostreae (calcined) 6 parts, Herb Gynostemmae Pentaphylli 6 parts, Herba Morindae Parvifoliae 6 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 5 parts, Rhizoma Imperatae 10 parts, Folium Callicarpae Formosanae 4 parts, Herba Patriniae 2 parts, Fructus Mori 6 parts.
Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 16 parts, Herba Dendrobii 8 parts, Fructus Evodiae 8 parts, Semen Raphani 16 parts, Caulis Perillae 14 parts, Endothelium Corneum Gigeriae Galli 11 parts, the Rhizoma Pinelliae 3 parts, Herba Selaginellae Uncinatae 5 parts, Rhizoma Sparganii 13 parts, Rhizoma Acori Graminei 14 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 12 parts, Fructus Hordei Germinatus 3 parts, Radix Inulae 1 part, 4 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 11 parts, Pericarpium Citri Reticulatae 4 parts, Flos Inulae 14 parts, Semen Sinapis Albae 8 parts, the Radix Linderae 3 parts, Fructus Akebiae 6 parts, Fructus Citri Sarcodactylis 17 parts, Semen Aesculi 15 parts, Caulis Polygoni Multiflori 7 parts, Concha Ostreae (calcined) 11 parts, Herb Gynostemmae Pentaphylli 10 parts, Herba Morindae Parvifoliae 9 parts, Radix Et Caulis Acanthopanacis Senticosi 13 parts, Semen Coicis 7 parts, Rhizoma Imperatae 11 parts, Folium Callicarpae Formosanae 3 parts, Herba Patriniae 1 part, Fructus Mori 10 parts.
Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 15 parts, Herba Dendrobii 9 parts, Fructus Evodiae 7 parts, Semen Raphani 19 parts, Caulis Perillae 13 parts, Endothelium Corneum Gigeriae Galli 10 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 4 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 11 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 10 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 3 parts, 6 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 9 parts, Pericarpium Citri Reticulatae 5 parts, Flos Inulae 12 parts, Semen Sinapis Albae 7 parts, the Radix Linderae 5 parts, Fructus Akebiae 9 parts, Fructus Citri Sarcodactylis 15 parts, Semen Aesculi 12 parts, Caulis Polygoni Multiflori 5 parts, Concha Ostreae (calcined) 9 parts, Herb Gynostemmae Pentaphylli 8 parts, Herba Morindae Parvifoliae 8 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 9 parts, Rhizoma Imperatae 12 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 3 parts, Fructus Mori 8 parts.
Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 14 parts, Herba Dendrobii 9 parts, Fructus Evodiae 6 parts, Semen Raphani 17 parts, Caulis Perillae 13 parts, Endothelium Corneum Gigeriae Galli 10 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 4 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 11 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 10 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 3 parts, 3 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 8 parts, Pericarpium Citri Reticulatae 5 parts, Flos Inulae 15 parts, Semen Sinapis Albae 7 parts, the Radix Linderae 2 parts, Fructus Akebiae 4 parts, Fructus Citri Sarcodactylis 19 parts, Semen Aesculi 14 parts, Caulis Polygoni Multiflori 6 parts, Concha Ostreae (calcined) 7 parts, Herb Gynostemmae Pentaphylli 8 parts, Herba Morindae Parvifoliae 8 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 4 parts, Rhizoma Imperatae 9 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 3 parts, Fructus Mori 8 parts.
Further, described Chinese medicine composition is prepared in accordance with the following steps:
(1) each medical material is got according to components by weight percent, pulverized by pulverizer after mixing, obtaining medicated powder fineness is 80-120 object mixture, and it is 95% alcohol reflux 2 times that mixture adds determining alcohol, first time adds the ethanol relative to this mixture quality 8 times amount, refluxes 2 hours; Second time adds the ethanol relative to this mixture quality 7 times amount, refluxes 1 hour, filters; Merge 2 filtrates, being evaporated to temperature is that at 60 DEG C, relative density is the thick paste of 1.10 ~ 1.13, for subsequent use; Volatilize ethanol simultaneously, and medicinal residues are continued to employ;
(2) medicinal residues that ethanol extraction in step (1) is crossed are decocted with water twice; First time adds the water relative to this mixture 8 times amount, decocts 2 hours, and second time adds the water relative to this mixture 7 times amount, decocts 1 hour, filters; Merge 2 filtrates, be evaporated to the thick paste that temperature is relative density 1.10 ~ 1.12 at 60 DEG C, for subsequent use;
(3) step (1), (2) concentrated thick paste obtained are merged, mixing, be evaporated to that temperature is 60 DEG C, the clear paste of relative density 1.30 ~ 1.32 further, after dry, pulverize subsequently, make 80 order fine powders;
(4) by the 80 order fine powders that step (3) is obtained, after adding suitable amount of sucrose, dextrin mixing, take ethanol as wetting agent, granulate, dry, granulate, can obtain granule; Or after 80 obtained for step (3) order fine powder packagings, make powder; Or the 80 order fine powders that step (3) is obtained are added appropriate micropowder silica gel, α-galactose mixing, take ethanol as wetting agent, granulate, dry, granulate, encapsulated, obtained capsule; Or the 80 order fine powders that step (3) is obtained are added suitable amount of sucrose, dextrin mixing, take ethanol as wetting agent, granulate, dry, granulate, tabletting, obtained tablet.
The invention still further relates to the application of a kind of described Chinese medicine composition being used for the treatment of chronic gastritis in treatment chronic gastritis medicine.
The Chinese medicine composition being used for the treatment of chronic gastritis provided by the present invention, it for raw material, gives full play to the property of medicine of each component with common Chinese herbal medicine:
Cortex Magnoliae Officinalis: bitter, pungent, temperature.Return spleen, stomach, lung, large intestine channel.Effect with cure mainly: dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
Herba Dendrobii sweet in the mouth, cold nature, return stomach, kidney channel.Function cures mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.Herba Dendrobii, replenishing YIN and removing heat Radix Ophiopogonis, reinforcing stomach reg fluid.
Fructus Evodiae, pungent, bitter, heat; Slightly poisonous.Return liver, spleen, stomach, kidney channel.Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For headache due to JUE YIN disorder, colic of cold type is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, dysmenorrhea, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea, external treatment aphtha; Hypertension.
Semen Raphani: pungent, sweet, flat.Return lung, spleen, stomach warp.Effect with cure mainly: help digestion de-swelling, lowering the adverse-rising QI to resolve phlegm.For retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant heap soil or fertilizer over and around the roots is breathed with cough.
Caulis Perillae is the stem of labiate Folium Perillae or wild Folium Perillae, nature and flavor acrid in the mouth; Return spleen, stomach, lung meridian.Function cures mainly: regulating the flow of QI to ease the stomach; Antiabortive; And blood.Main stagnation of QI in spleen and stomach; Gastral cavity abdomen feeling of fullness, nausea is got along well, edema beriberi, and spitting of blood tells nosebleed.
Endothelium Corneum Gigeriae Galli: property is sweet puts down, be slightly cold, nontoxic, returns spleen, stomach, kidney, urinary bladder channel.Cure mainly: can promoting digestion and invigorating the stomach, arresting seminal emission, fossil.Removing food stagnancy is stagnant, strengthening the spleen and stomach.Control food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.
The Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.
Herba Selaginellae Uncinatae: lightly seasoned, property is put down.For the herb of Spikemoss plant CUIYUNCAO.There is clearing away heat-damp and promoting diuresis, removing toxic substances, repercussive, effect of hemostasis.For jaundice, dysentery, edema, rheumatic arthralgia, cough is spitted blood, retropharyngeal abscess, anal fistula, knife injury, scalds.
Rhizoma Sparganii: acrid in the mouth; Puckery; Cool.Enter liver.Spleen channel.Control lump in the abdomen, gather, distending pain over the hypochondrium, food stagnation distending pain, dysmenorrhea, amenorrhea, postnatal blood stasis is suffered from abdominal pain, traumatic injury.Cough due to lung-heat controlled by mongolian medicine, asthma abundant expectoration, liver-heat, arteries and veins heat, the hot hectic fever due to YIN-deficiency of consumptive disease, and " precious day " is sick, fracture.
Rhizoma Acori Graminei: pungent, bitter, temperature.GUIXIN, stomach warp.Effect with cure mainly: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, the insane disease of coma, forgetful deafness.
Herba Pogostemonis, pungent, tepor.As lung, spleen, stomach warp.Function cures mainly: fast gas, and in, ward off dirty, damp eliminating, cure cold heat-damp in summer, cold and heat, and headache, breast wrist painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.
Fructus Piperis Longi, acrid in the mouth, warm in nature, return stomach, spleen, kidney channel, there is cold relieving, invigorate blood circulation, warming YANG, blood stasis dispelling, the effect such as to regulate the flow of vital energy, be mainly used in the diseases such as treatment angina pectoris, stomachache, diarrhoea.
Fructus Hordei Germinatus nature and flavor: sweet are flat.Gui Jing: return spleen, stomach warp.Effect: spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Cure mainly: do not disappear for food stagnation, women's ablactation, Fructus Hordei Germinatus (parched to brown) relieving dyspepsia.Do not disappear for food stagnation, abdominal distention.
Radix Inulae: pungent, bitter, temperature.Return liver, board warp.Effect with cure mainly: invigorating the spleen and regulating the stomach, promoting the flow of QI for relieving the stagnancy, pain relieving is antiabortive.For the breast side of body, both abdominal distention and pain, vomiting dysentery, the breast side of body is dampened, and feels a pain in the chest when breathing and has a pain, frequent fetal movement.
Fructus Amomi Rotundus, pungent, temperature.Return lung, spleen, stomach warp.Removing dampness disappears painful abdominal mass, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving.For turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear.
Rhizoma Corydalis, bitter in the mouth, pungent, warm in nature; Return liver, the heart, stomach warp; Benefaction is wandered away, and can rise and can fall, have promoting blood circulation to remove blood stasis, effect of promoting the circulation of QI to relieve pain.Cure mainly obstruction of qi in the chest and cardialgia, the side of body rib, all pains of gastral cavity abdomen, headache, lumbago, colicky, bones and muscles pain, dysmenorrhea, amenorrhea, puerperal, the stasis of blood was suffered from abdominal pain, traumatic injury.
Pericarpium Citri Reticulatae is warm in nature, acrid in the mouth, bitter in the mouth.Enter spleen channel, stomach warp, lung meridian.Regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach.Abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool.Phlegm-damp stops up the cough and asthma of lung.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Compendium of Material Medica: it is to hundred and always get chess and to regulate the flow of vital energy the merit of dampness, then mending with tonic, then rushes down with cathartic, then rise with Hydrargyri Oxydum Rubrum, then falling with falling medicine.Spleen is the mother of vigour, lung be take the photograph gas want, therefore Pericarpium Citri tangerinae be two through edema caused by disorder of QI want, but with join and reinforcing and reducing lifting also." daily book on Chinese herbal medicine ": can fall apart and can rush down, can temperature can mend, can disappear diaphragm gas, and reduce phlegm saliva, and spleen antitussive, logical five types of stranguria.
Flos Inulae, bitter, pungent, salty, tepor.Return lung, spleen, stomach, large intestine channel.Function cures mainly: sending down the abnormal ascending QI, expectorant, row water, preventing or arresting vomiting.For cough due to wind and cold, phlegm retention stores knot, chest and diaphragm feeling of fullness, dyspnea and cough with excessive sputum, vomiting eructation, epigastric oppression and rigidity.
Semen Sinapis Albae: pungent, warm.Return lung, liver, spleen, stomach, heart channel.Reduce phlegm by drink, mass dissipating and swelling eliminating.Clinical in cough with asthma abundant expectoration, fullness in the chest and hypochondriac pain, numb limbs and tense tendons, arthralgia, the diseases such as multiple abscess caused by damp-phlegm.
The Radix Linderae: pungent, yearningly.Return lung, spleen, kidney, urinary bladder channel.Effect with cure mainly: pleasant pain relieving, warming kidney for dispelling cold.For chest and abdomen swelling and pain, QI rising in reverse order dyspnea with rapid respiration, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia, dysmenorrhea.
Fructus Akebiae, sweet, cold.Function cures mainly: liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis.Treating the liver peratodynia, gastric heat food is slow-witted, excessive thirst, also Hakuri, lumbago, hypochondriac pain, hernia, cave warp, and uterus drops.
Fructus Citri Sarcodactylis: pungent, bitter, sour, temperature; Return liver, spleen, lung meridian." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " Fructus Citri Sarcodactylis disappears cold syndrome of the stomach expectorant, controls gastric qi pain, the only cold pain in face, and middle circulation of qi promoting for tonifying liver warming the stomach, anti-nausea." " book on Chinese herbal medicine is new again ": " control gas soothing liver-QI, stomach function regulating reduces phlegm, and removing mass controls dysphagia and regurgitation, eliminating mass abdominal mass scrofula." liver-smoothing, qi-regulating, and stomach and alleviating pain.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite is vomitted.Limettin contained by this product shrinks guinea-pig isolated trachea caused by histamine, has antagonism; Show there is certain antiallergic activity in the isolated ileum segments in guinea pigs of Ovum Gallus domesticus album sensitization and isolated tracheal test.This product ethanol extract has obvious inhibitory action to rat, rabbits infestines, and intravenous administration also has same inhibitory action to anesthetized cat, rabbit at body intestinal tube.Fructus Citri Sarcodactylis ethanol extract significantly can increase the coronary flow of guinea pig isolated heart and improve the hypoxia-bearing capability of mice; Protective effect is had to the myocardial ischemia that rat causes because of pituitrin.
Semen Aesculi is the fruits and seeds of Hippocastanaceae plant Aesculus chinensis Bunge, Radix Aesculi or Aesculus.Sweet in the mouth; Warm in nature.Return liver; Stomach warp.Function cures mainly: soothing the liver; Regulate the flow of vital energy; Alleviating distention in middle-JIAO; Pain relieving.The main breast side of body; Distending pain of the breast; Dysmenorrhea; Gastric abscess.
Caulis Polygoni Multiflori: sweet micro-hardship is flat.Enter the heart, Liver Channel.Have and nourish heart, calm the nerves, dredging collateral, the effect such as to dispel the wind.Control insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.
Concha Ostreae (calcined), salty, be slightly cold.Return liver, gallbladder, kidney channel.Tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Herb Gynostemmae Pentaphylli: sweet in the mouth, hardship, cold nature; Return lung meridian, spleen channel, kidney channel.Energy QI invigorating, calms the nerves, blood pressure lowering, heat-clearing and toxic substances removing, eliminating phlegm and stopping cough.After small number of patients is taken medicine, there is the symptom such as nausea and vomiting, abdominal distention diarrhoea (or constipation), dizziness, dim eyesight, tinnitus.After taking Herb Gynostemmae Pentaphylli, enterogastric peristalsis is accelerated, and it is long that appetite increases the resistance to time of hungering and thirst, and not only treats constipation but also control loose stool.Reaction that is excited to cerebral cortex and that suppress can keep suitable balance, has dual regulation to nervus centralis.There is excellent analgesia, sleeping, antitonic effect.In reduction myocardial wall anxiety, relax on the basis of cerebrovascular and peripheral vascular resistance, heart and brain vigor can be strengthened, strengthen coronary flow, relax arteriosclerosis, impel entirety to circulate more vigorous and smooth.Experiment proves, and the not rich Herb Gynostemmae Pentaphylli group that takes of diet, and and avoid meat and refuses to obey Herb Gynostemmae Pentaphylli group, make regular check on and compare, body inner bag is consolidated close with neutral fat content.Herb Gynostemmae Pentaphylli has benign transformed regulating action to body fat mass in human body as can be seen here.Take Herb Gynostemmae Pentaphylli to compare with the mouse of disobedience, the about long 31-57% of its swimming time, and antisecosis is also faster, after people takes Herb Gynostemmae Pentaphylli, physical energy is more abundant, indefatigability, be also easy to recover, thus work efficiency increases even if tired.Human body part function is weak, and can produce Cucumber irritated, and form the diseases such as bronchus is panted, skin rashes, arthralgia, Herb Gynostemmae Pentaphylli is rather good to these sick effects.
Herba Morindae Parvifoliae is the Herb of dicotyledon medicine Maguireothamnus speciosus spire Radix Morindae Officinalis.Nature and flavor are sweet, cool.Function cures mainly: heat-clearing and toxic substances removing; Eliminating stasis to stop pain; Stomach function regulating removing dampness.Main cold cough; Pertussis; Dyspepsia; Eczema; Traumatic injury, lumbar muscle strain.
Radix Et Caulis Acanthopanacis Senticosi: acrid in the mouth, hardship, micro-sweet, warm in nature, enters spleen, kidney, heart channel, there is replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, effect of expelling wind and removing dampness, soft for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity, be slow in action, the card such as body weakness with emaciation is weak, traumatic injury, fracture, edema, beriberi, uncontrolled urination are itched.The sweet A of Radix Et Caulis Acanthopanacis Senticosi is carotene, also containing this constituents in people Ginseng.The excretion of cholesterol can be promoted in human body, the too high disease of blood cholesterol level can be prevented and treated.The sweet B of Radix Et Caulis Acanthopanacis Senticosi is Syringa oblata Lindl. element (Syringin), is the main strong composition of Radix Et Caulis Acanthopanacis Senticosi, has short gonad, radioprotective, fatigue-resisting function, has the physiologically active similar to Ren Ginseng Saponin.Radix Et Caulis Acanthopanacis Senticosi is containing super oxidation disproportionation ferment SOD (Superoxidedimutase) complex, SOD has good anti-oxidation function, the effect of human immunity and the attack of opposing free radical can be strengthened, there is antioxidation, body immunity can be strengthened, prevent aging and promotion health.
Semen Coicis, sweet in the mouth, light, cold nature.Return spleen, stomach, lung meridian.Energy promoting diuresis to eliminate damp pathogen, damp eliminating eliminating impediment, invigorating the spleen to arrest diarrhea, clearing away heat and discharging pus.Cure mainly dysuria, edema, beriberi, arthralgia chiefly caused by damp pathogen contracture, hygropyrexia from the beginning of and the card such as diarrhea due to hypofunction of the spleen, lung abscess, acute appendicitis.
Rhizoma Imperatae, sweet, cold.Return lung, stomach, urinary bladder channel.Function cures mainly: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema.
Folium Callicarpae Formosanae is bitter, puckery, cool.Return liver, lung, stomach warp.Removing heat from blood astringing to arrest bleeding, dissipating blood stasis removing toxic substances and promoting subsidence of swelling.For epistaxis, spitting of blood, spits blood, has blood in stool, metrorrhagia, traumatic hemorrhage, pathopyretic ulcer, burn due to hot liquid or fire.
Herba Patriniae, pungent, bitter, cool, return stomach, large intestine, Liver Channel, heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused breast abdomen pain of the excess-heat stasis of blood, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.
Fructus Mori: sweet, sour, cold.GUIXIN, liver, kidney channel.Effect with cure mainly: YIN nourishing of enriching blood, promote the production of body fluid and moisturize.For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.
The traditional Chinese medical science is thought, stomach is sun soil, and preferring moisture to dryness is the big source of the vital organs of the human body, the internal organs of the many blood of many gas, main digesting food of being received, with logical reduce to suitable.Liver and stomach are the relations that wooden soil is taken advantage of gram, and with the passing of time stagnation of liver-QI, both can occur fire-transformation impairment of YIN, can cause again knot in blood stasis, and so far stomachache increases the weight of.Spleen and stomach, a dirty internal organs, the exterior and the interior each other, altogether main lifting, therefore gastropathy relates to spleen more, the splenopathy also can and stomach.Spleen YANG deficiency is then cold from interior life, and stomach loses replenishing vital QI with drugs of warm nature and cold of insufficiency type and stomachache; Spleen profit is too late, or dryness of the stomach too, causes stomach mistake and moistens foster, form yin deficiency and gastralgia.Cold being transformed following YANG-insufficiency, then hematogenous blockage, puckeryly form the stasis of blood; Deficient YIN converting into heat, then burn stomach network and hemorrhage.The scorching hot pain of stomach-yin deficiency Patients with Chronic Gastritis gastral cavilty, noisy discomfort, though hungry and poor appetite, thirsty, defecates involved and abstruse, and red tongue has crackle, the stripping of tongue fur light or few tongue, pulse condition stringy and thready pulse number.This disease is incoordination between the liver and spleen, stomach-Yin virtual loss; Therapeutic Principle is soothing liver and strengthening spleen, tonifying YIN nourishing the stomach.
Concha Ostreae (calcined) tranquillization with heavy prescription in Chinese medicine composition object space of the present invention, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving, Herba Dendrobii reinforcing stomach reg fluid, nourishing YIN and clearing away heat, Fructus Evodiae dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal, Fructus Piperis Longi cold relieving, invigorates blood circulation, warming YANG, blood stasis dispelling, to regulate the flow of vital energy, Rhizoma Corydalis promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain, Fructus Amomi Rotundus removing dampness disappears painful abdominal mass, circulation of qi promoting warming middle-JIAO, Concha Ostreae (calcined), Herba Dendrobii, Fructus Evodiae, Fructus Piperis Longi, Rhizoma Corydalis, Fructus Amomi Rotundus are monarch drug, YANG hyperactivity suppressing nourishing YIN, reinforcing stomach reg fluid, expelling cold pathogen and lowering adverse QI, blood circulation promoting regulates qi, expelling wind and cold;
Caulis Perillae regulating the flow of QI to ease the stomach, Endothelium Corneum Gigeriae Galli promoting digestion and invigorating the stomach, Rhizoma Pinelliae drying dampness to eliminate phlegm, dissolving lump and resolving mass, Rhizoma Acori Graminei removing dampness is whetted the appetite, refreshment Fructus Alpiniae Oxyphyllae, Herba Pogostemonis and middle damp eliminating, Fructus Hordei Germinatus, Radix Inulae spleen benefiting and stimulating the appetite, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, Fructus Akebiae vital energy regualting and blood circulation-promoting, Fructus Citri Sarcodactylis liver-smoothing, qi-regulating, and stomach and alleviating pain, Herb Gynostemmae Pentaphylli benefiting vital QI for tranquillizing, Radix Et Caulis Acanthopanacis Senticosi replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, expelling wind and removing dampness, Semen Coicis promoting diuresis to eliminate damp pathogen, damp eliminating eliminating impediment, invigorating the spleen to arrest diarrhea, clearing away heat and discharging pus, Fructus Mori are enriched blood YIN nourishing, and above all medicines are ministerial drug, regulating the flow of QI to ease the stomach, removing dampness appetizing, regulating qi-flowing for strengthening spleen, YIN nourishing of calming the nerves;
Herba Selaginellae Uncinatae, Folium Callicarpae Formosanae, Herba Patriniae, Semen Sinapis Albae, Semen Aesculi, Caulis Polygoni Multiflori, the Radix Linderae, Rhizoma Imperatae, Herba Morindae Parvifoliae etc. make for assistant, clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, cooling blood for hemostasis, mass dissipating and swelling eliminating, warming kidney for dispelling cold, dredging collateral dispels the wind, and strengthens effect of monarch drug and ministerial drug soothing liver and strengthening spleen in we, tonifying YIN nourishing the stomach.
It is reasonably combined that Chinese medicine composition of the present invention adopts various raw material of Chinese medicine to carry out, and the composition proportion provided makes each raw material serve good synergism, and promoting the circulation of QI to relieve pain, soothing the liver, the spleen invigorating of regulating the flow of vital energy disappear stagnant, and combine Be very effective in treatment chronic gastritis.And have no adverse reaction, there is short treating period, instant effect, the advantage of non-relapse after healing.The preparation method of Chinese medicine composition of the present invention, technique is simple, is easy to operation.
Detailed description of the invention
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with embodiment, technical scheme of the present invention is clearly and completely described.Obviously, described embodiment is a part of the present invention, instead of whole embodiments.Based on described embodiments of the invention, the every other embodiment that those of ordinary skill in the art obtain under without the need to the prerequisite of creative work, all belongs to the scope of protection of the invention.
Embodiment 1:
A kind of Chinese medicine composition being used for the treatment of chronic gastritis of the present invention, get following traditional Chinese medicine raw medicine: Cortex Magnoliae Officinalis 12 parts, Herba Dendrobii 10 parts, Fructus Evodiae 9 parts, Semen Raphani 15 parts, Caulis Perillae 15 parts, Endothelium Corneum Gigeriae Galli 8 parts, the Rhizoma Pinelliae 5 parts, Herba Selaginellae Uncinatae 3 parts, Rhizoma Sparganii 14 parts, Rhizoma Acori Graminei 9 parts, Herba Pogostemonis 6 parts, Fructus Piperis Longi 8 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 1 part, 6 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 8 parts, Pericarpium Citri Reticulatae 3 parts, Flos Inulae 15 parts, Semen Sinapis Albae 5 parts, the Radix Linderae 3 parts, Fructus Akebiae 5 parts, Fructus Citri Sarcodactylis 12 parts, Semen Aesculi 16 parts, Caulis Polygoni Multiflori 3 parts, Concha Ostreae (calcined) 12 parts, Herb Gynostemmae Pentaphylli 10 parts, Herba Morindae Parvifoliae 5 parts, Radix Et Caulis Acanthopanacis Senticosi 16 parts, Semen Coicis 10 parts, Rhizoma Imperatae 8 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 1 part, Fructus Mori 10 parts.
Wherein, described Chinese medicine composition is prepared according to following method:
(1) each medical material is got according to components by weight percent, pulverized by pulverizer after mixing, obtaining medicated powder fineness is 80-120 object mixture, and it is 95% alcohol reflux 2 times that mixture adds determining alcohol, first time adds the ethanol relative to this mixture quality 8 times amount, refluxes 2 hours; Second time adds the ethanol relative to this mixture quality 7 times amount, refluxes 1 hour, filters; Merge 2 filtrates, being evaporated to temperature is that at 60 DEG C, relative density is the thick paste of 1.10 ~ 1.13, for subsequent use; Volatilize ethanol simultaneously, and medicinal residues are continued to employ;
(2) medicinal residues that ethanol extraction in step (1) is crossed are decocted with water twice; First time adds the water relative to this mixture 8 times amount, decocts 2 hours, and second time adds the water relative to this mixture 7 times amount, decocts 1 hour, filters; Merge 2 filtrates, be evaporated to the thick paste that temperature is relative density 1.10 ~ 1.12 at 60 DEG C, for subsequent use;
(3) step (1), (2) concentrated thick paste obtained are merged, mixing, be evaporated to that temperature is 60 DEG C, the clear paste of relative density 1.30 ~ 1.32 further, after dry, pulverize subsequently, make 80 order fine powders;
(4) by the 80 order fine powders that step (3) is obtained, after adding suitable amount of sucrose, dextrin mixing, take ethanol as wetting agent, granulate, dry, granulate, can obtain granule; Or after 80 obtained for step (3) order fine powder packagings, make powder; Or the 80 order fine powders that step (3) is obtained are added appropriate micropowder silica gel, α-galactose mixing, take ethanol as wetting agent, granulate, dry, granulate, encapsulated, obtained capsule; Or the 80 order fine powders that step (3) is obtained are added suitable amount of sucrose, dextrin mixing, take ethanol as wetting agent, granulate, dry, granulate, tabletting, obtained tablet.
Model case:
Wang, man, 33 years old, Qingdao City Laoshan District people.Patient main suit: epigastrium is pain 3 wheat harvesting period repeatedly.Time hungry, very, postprandial pain subtracts pain.And with flatulence, noisy, belch, occasionally have nausea and vomiting, dry mouth with bitter taste, swallow sense of obstruction, rare when doing during stool, sensation of oppression over the chest with shortness of breath, the tired power of body, vexed easily dry, feel cold.Adopt Tablets, one day twice, each two panels, sooner or later one after each meal, after one week, symptom disappears substantially, occasionally has loose stool; Continue to take 2 courses for the treatment of, all symptoms all disappear, and cure.
Embodiment 2:
A kind of Chinese medicine composition being used for the treatment of chronic gastritis of the present invention, get following traditional Chinese medicine raw medicine: Cortex Magnoliae Officinalis 17 parts, Herba Dendrobii 12 parts, Fructus Evodiae 4 parts, Semen Raphani 20 parts, Caulis Perillae 10 parts, Endothelium Corneum Gigeriae Galli 12 parts, the Rhizoma Pinelliae 2 parts, Herba Selaginellae Uncinatae 7 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 15 parts, Herba Pogostemonis 3 parts, Fructus Piperis Longi 13 parts, Fructus Hordei Germinatus 3 parts, Radix Inulae 3 parts, 4 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 10 parts, Pericarpium Citri Reticulatae 4 parts, Flos Inulae 13 parts, Semen Sinapis Albae 6 parts, the Radix Linderae 4 parts, Fructus Akebiae 8 parts, Fructus Citri Sarcodactylis 20 parts, Semen Aesculi 10 parts, Caulis Polygoni Multiflori 8 parts, Concha Ostreae (calcined) 5 parts, Herb Gynostemmae Pentaphylli 5 parts, Herba Morindae Parvifoliae 10 parts, Radix Et Caulis Acanthopanacis Senticosi 13 parts, Semen Coicis 3 parts, Rhizoma Imperatae 13 parts, Folium Callicarpae Formosanae 3 parts, Herba Patriniae 3 parts, Fructus Mori 5 parts.
Preparation method is with embodiment 1.
Model case:
What certain, man, 50 years old, Qingdao Jimo people.Patient suffers from chronic gastritis 2 years, the flatulence that has a stomach-ache, returns acid during morbidity, has burn feeling, increases the weight of after the meal.Once multi-treatment, but poor effect.Adopt the powder of the present invention, one day twice, each two bags, sooner or later one after each meal, after 2 weeks, the flatulence that has a stomach-ache, return the symptoms such as acid and be eased, continue to take 3 courses for the treatment of, symptom disappears completely, cures.Follow up a case by regular visits to and have no recurrence half a year.
Embodiment 3:
A kind of Chinese medicine composition being used for the treatment of chronic gastritis of the present invention, get following traditional Chinese medicine raw medicine: Cortex Magnoliae Officinalis 13 parts, Herba Dendrobii 7 parts, Fructus Evodiae 5 parts, Semen Raphani 18 parts, Caulis Perillae 11 parts, Endothelium Corneum Gigeriae Galli 9 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 6 parts, Rhizoma Sparganii 12 parts, Rhizoma Acori Graminei 13 parts, Herba Pogostemonis 4 parts, Fructus Piperis Longi 9 parts, Fructus Hordei Germinatus 4 parts, Radix Inulae 2 parts, 5 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 12 parts, Pericarpium Citri Reticulatae 3 parts, Flos Inulae 12 parts, Semen Sinapis Albae 9 parts, the Radix Linderae 4 parts, Fructus Akebiae 7 parts, Fructus Citri Sarcodactylis 13 parts, Semen Aesculi 11 parts, Caulis Polygoni Multiflori 4 parts, Concha Ostreae (calcined) 6 parts, Herb Gynostemmae Pentaphylli 6 parts, Herba Morindae Parvifoliae 6 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 5 parts, Rhizoma Imperatae 10 parts, Folium Callicarpae Formosanae 4 parts, Herba Patriniae 2 parts, Fructus Mori 6 parts.
Preparation method is with embodiment 1.
Model case:
Week certain, man, 41 years old, people from Laiyang, Yantai.Patient's readme suffers from chronic atrophic gastritis more than 2 years, recent anorexia, likes coolly to detest greasy, and abdominal distention, epigastrium dull pain discomfort companion belch, returns acid, heartburn sense, and stool once a day, but defecate and glue freely by self-induction, and vexed gas is hot-tempered; Take granule of the present invention, one day twice, each one bag, sooner or later one after each meal, after one week, conscious belch after meal, acid regurgitation, heartburn sense slightly alleviate; After continuing to take 2 courses for the treatment of, abdominal distention, stomachache are not obvious; Diet increases, comfortable in stomach after food, without singultus, heartburn, acid regurgitation symptom; Continue to strengthen and take 2 courses for the treatment of, cure.
Embodiment 4:
A kind of Chinese medicine composition being used for the treatment of chronic gastritis of the present invention, get following traditional Chinese medicine raw medicine: Cortex Magnoliae Officinalis 16 parts, Herba Dendrobii 8 parts, Fructus Evodiae 8 parts, Semen Raphani 16 parts, Caulis Perillae 14 parts, Endothelium Corneum Gigeriae Galli 11 parts, the Rhizoma Pinelliae 3 parts, Herba Selaginellae Uncinatae 5 parts, Rhizoma Sparganii 13 parts, Rhizoma Acori Graminei 14 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 12 parts, Fructus Hordei Germinatus 3 parts, Radix Inulae 1 part, 4 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 11 parts, Pericarpium Citri Reticulatae 4 parts, Flos Inulae 14 parts, Semen Sinapis Albae 8 parts, the Radix Linderae 3 parts, Fructus Akebiae 6 parts, Fructus Citri Sarcodactylis 17 parts, Semen Aesculi 15 parts, Caulis Polygoni Multiflori 7 parts, Concha Ostreae (calcined) 11 parts, Herb Gynostemmae Pentaphylli 10 parts, Herba Morindae Parvifoliae 9 parts, Radix Et Caulis Acanthopanacis Senticosi 13 parts, Semen Coicis 7 parts, Rhizoma Imperatae 11 parts, Folium Callicarpae Formosanae 3 parts, Herba Patriniae 1 part, Fructus Mori 10 parts.
Preparation method is with embodiment 1.
Model case:
Hair certain, man, 31 years old, people from Laiyang, Yantai.Patient's private prosecution sensation of oppression over the chest with shortness of breath, the tired power of body, stomach pain, distension, suffer from cold, the postemphasis of diet raw food, and belch is weak, poor appetite, and namely feed feels glutted on a small quantity, comfortable on an empty stomach, every day 2-3 time of defecating, rare half congealed; Look into through gastroscope and be diagnosed as: chronic gastritis.Take powder of the present invention, every day 2 doses, after 10 days, food is received and is become good, and paroxysmal pain, diarrhoea number of times reduce; Continuous take 2 courses for the treatment of, paroxysmal pain, diarrhoea all disappear, every day defecation 1 time, feces is normal; Continue to strengthen and take 2 courses for the treatment of, cure.
Embodiment 5:
A kind of Chinese medicine composition being used for the treatment of chronic gastritis of the present invention, get following traditional Chinese medicine raw medicine: Cortex Magnoliae Officinalis 15 parts, Herba Dendrobii 9 parts, Fructus Evodiae 7 parts, Semen Raphani 19 parts, Caulis Perillae 13 parts, Endothelium Corneum Gigeriae Galli 10 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 4 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 11 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 10 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 3 parts, 6 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 9 parts, Pericarpium Citri Reticulatae 5 parts, Flos Inulae 12 parts, Semen Sinapis Albae 7 parts, the Radix Linderae 5 parts, Fructus Akebiae 9 parts, Fructus Citri Sarcodactylis 15 parts, Semen Aesculi 12 parts, Caulis Polygoni Multiflori 5 parts, Concha Ostreae (calcined) 9 parts, Herb Gynostemmae Pentaphylli 8 parts, Herba Morindae Parvifoliae 8 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 9 parts, Rhizoma Imperatae 12 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 3 parts, Fructus Mori 8 parts.
Preparation method is with embodiment 1.
Model case:
Practise certain, female, 29 years old, people from Lixia District, Jinan.Patient suffers from chronic gastritis more than 3 years, and often stomachache, flatulence, acid regurgitation, with inappetence, postprandial pain very, is chronic gastritis through hospital diagnosis.Take capsule of the present invention, every day twice, each 3, sooner or later one after each meal, after 1 week, symptom obviously alleviates, and continues to take 1 course for the treatment of, and all diseases disappear, recovery from illness.Follow up a case by regular visits to after 1 year without recurrence.
Embodiment 6:
A kind of Chinese medicine composition being used for the treatment of chronic gastritis of the present invention, get following traditional Chinese medicine raw medicine: Cortex Magnoliae Officinalis 14 parts, Herba Dendrobii 9 parts, Fructus Evodiae 6 parts, Semen Raphani 17 parts, Caulis Perillae 13 parts, Endothelium Corneum Gigeriae Galli 10 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 4 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 11 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 10 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 3 parts, 3 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 8 parts, Pericarpium Citri Reticulatae 5 parts, Flos Inulae 15 parts, Semen Sinapis Albae 7 parts, the Radix Linderae 2 parts, Fructus Akebiae 4 parts, Fructus Citri Sarcodactylis 19 parts, Semen Aesculi 14 parts, Caulis Polygoni Multiflori 6 parts, Concha Ostreae (calcined) 7 parts, Herb Gynostemmae Pentaphylli 8 parts, Herba Morindae Parvifoliae 8 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 4 parts, Rhizoma Imperatae 9 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 3 parts, Fructus Mori 8 parts.
Preparation method is with embodiment 1.
Model case:
Peng, man, 55 years old, Qingdao Jimo people.Patient suffered from chronic gastritis more than 4 years, started sensuously abdominal part and often had a dull ache, do not like diet, distension and fullness in the abdomen, and abdominal distention gradually increased the weight of afterwards, and belch is frequent, and after belch, pain slightly subtracts, and has heartburn, acid regurgitation once in a while, is chronic gastritis through hospital diagnosis.Take multiple Western medicine, when starting to take, symptom slightly alleviates, but easily repeatedly, does not all obtain satisfactory curative effect.Take the tablet of the present invention, one day twice, each two panels, sooner or later one after each meal, after 1 week, above-mentioned symptom all disappears, recovery from illness.Follow up a case by regular visits to so far without recurrence.
Acute toxicity test:
Application Kunming mouse 50, male and female half and half, body weight 22 ~ 25g, carries out acute toxicity test.Mice is divided into two groups at random, i.e. matched group and administration group, before experiment, fasting 12 hours, is dissolved in water by Chinese powder medicine prepared by embodiments of the invention 3, (concentration is 6.91g crude drug/ml, maximum concentration) gavage, gavage volume is 5ml/kg (namely unit dosage form is 34.55 crude drugs/kg), and matched group gives normal saline, administration in one day 3 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Mouse oral gavage medicament of the present invention and LD50>34.55 crude drug/kg, maximum dosage-feeding 69.1 crude drugs/kg/ day every day.Chinese medicine preparation clinical application amount of the present invention be 6.0g crude drug/day/people, adult body weight in 60KG, average dosage is 0.101g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is in 24g) oral administration gavage Chinese medicine preparation of the present invention is 681 times of quantity.Therefore Chinese medicine preparation acute toxicity of the present invention is extremely low, clinical drug safety.
Long term toxicity test:
Powder prepared by Chinese medicine preparation embodiment 3 of the present invention presses 12.34,21.11 and 38.42g crude drug/kg continuous use 14 weeks (1.0ml/100g body weight to mice, every day 2 times) and drug withdrawal after 2 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine preparation of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 14 weeks and drug withdrawal are after 2 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine preparation of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Clinical reasoning:
In order to verify the effect of Chinese medicine composition of the present invention, in November ,-2014 in July, 2013, the routine Patients with Chronic Gastritis of outpatient service place Stochastic choice 190, two groups of patients are divided into matched group and treatment group, treatment group 95 example, wherein man 41 example, female 54 example, minimal ages is 22 years old, and max age is 67 years old, and the mean age is 44.1 ± 3.4 years old.Matched group all patients is 95 examples, and wherein male is 47 examples, and women is 48 examples, and minimal ages is 25 years old, and max age is 65 years old, and the mean age is 43.4 ± 3.6 years old.Matched group and observation group there was no significant difference (P > 0.05) in the physical data such as sex, age, the course of disease, has comparability.
Tcm diagnosis standard (the diagnosis tentative standard that in November, 1989, CAIM's digestive system disease Professional Committee formulated):
1. liver-stomach disharmony type: mainly want syndrome: 1. epigastric distending pain or pain string two side of body.2. belch is frequent.3. noisy pantothenic acid.Secondary syndrome: the 1. acute Active inflammation of gastric mucosa.2. bile reflux.Picture of the tongue pulse condition: body of the tongue is light red, white and thin fur or thick in vain; Stringy pulse.Pattern of syndrome is determined: 1. possess primary symptom two, tongue pulse condition meets substantially.2. possess primary symptom 1 and time disease 1, tongue pulse condition meets substantially.Possess any 1 person can determine.
2. weakness of the spleen and stomach (comprising deficiency and coldness) type: main syndromes: 1. vague epigastralgia.2. pain relieved by pressing happiness of having a stomachache is warm.3. feeling of distension and oppression feeling of fullness after food.4. appetite stimulator.5. loose stool diarrhoea.6. weak extremity are aching and limp.Secondary syndrome: 1. gastric mucosa is red and white with Bai Weizhu.2. mucus is thin and many.3. gastric acid is on the low side.Picture of the tongue pulse condition: 1. body of the tongue is light red, white and thin fur or white, has indentation.2. deep-thready pulse.Pattern of syndrome is determined: 1. possess main symptom 3, tongue arteries and veins meets substantially.2. possess primary symptom two and time disease 1, tongue arteries and veins meets substantially.Possess any 1 can determine.
3. spleen and stomach damp-heat type: main syndromes: the 1. scorching hot distending pain of gastral cavilty.2. bitter taste halitosis.3. yellowish urine.4. gastral cavity abdomen painful abdominal mass is vexed, thirst but no desire to drink.Secondary syndrome: gastric mucosa is acute, Active inflammation, congested rotten to the corn obviously.Picture of the tongue pulse condition: red tongue, limit point is dark red, and yellow fur is thick or greasy.Rolling pulse, tense pulse.Pattern of syndrome is determined: 1. possess primary symptom two, tongue arteries and veins meets substantially.2. possess primary symptom 1 and secondary disease, tongue arteries and veins meets substantially.Possess any 1 can determine.
4. type of deficiency of stomach yin: main syndromes: the 1. scorching hot pain of gastral cavilty.2. dry mouth and tougue.3. be hard and dry.Secondary syndrome: 1. gastric mucosa lamellar is red and white, and mucosa is thinning.2. gastric mucosa is dry, and mucus is few.3. gastric acid is on the low side.Picture of the tongue pulse condition: 1. red tongue with a little fluid or have crackle.2. thready pulse or stringy and thready pulse.Pattern of syndrome is determined: 1. possess primary symptom two and tongue arteries and veins meets.2. possess primary symptom 1 and secondary disease two, tongue arteries and veins meets substantially.Possess above any 1 can determine.
5. stomach network blood stasis type: main disease: 1. gastral cavilty localized pain, not pain relieved by pressing.2. have a stomach-ache and with the passing of time do not heal.3. ambassador's occult blood positive or black hemafecia.Secondary disease: the congested swelling of gastric mucosa, companion's ecchymosis or petechia.Picture of the tongue pulse condition: 1. dimly red tongue, or purple dark, or have ecchymosis.2. stringy and hesitant pulse.Pattern of syndrome is determined: 1. possess primary symptom two, tongue arteries and veins meets substantially.2. possess primary symptom 1 and add time disease; Tongue arteries and veins meets substantially.Possess above any 1 can determine.
Therapeutic Method
Treatment group: treatment group uses the tablet prepared in embodiment to treat, and every day 3 times, each two, 7 days courses for the treatment of, serve on 3 courses for the treatment of.
Matched group: take SANJIU WEITAI KELI, one time 1 bag, 2 times on the one, 15 days courses for the treatment of, serve on 3 courses for the treatment of.
Efficacy assessment standard
Recovery from illness: patient clinical symptom disappears completely, stomach is without pain, and appetite is recovered.
Effective: patient clinical symptom has remarkable alleviation, stomach pain symptom obviously alleviates, and attack times obviously reduces.
Effective: patient clinical symptom is alleviated to some extent, stomach pain symptom alleviates to some extent, and attack times reduces to some extent.
Invalid: patient clinical symptom is without any improvement.
Statistical method
This is organized all statistical datas and all adopts SPSS17.0 software to carry out analyzing and processing, with P < 0.05 for difference has statistical significance.
Two groups of therapeutic effect compare in table 1
Table 1 liang group patient effective percentage relative analysis
Group Number of cases Recovery from illness Effective Effectively Invalid Effectively total
Treatment group 95 71(74.7%) 16(16.8%) 7(7.4%) 1(1.1%) 94(98.9%)
Matched group 95 34(35.8%) 14(14.7%) 9(9.5%) 38(40%) 57(60%)
Wherein, total effective rate=cure rate+obvious effective rate.
As can be seen from Table 1, after the treatment of 3 courses for the treatment of, treatment by Chinese herbs group of the present invention, cure rate is up to 74.7%, and matched group cure rate is only 35.8%.The total effective rate for the treatment of group and matched group is respectively 98.9% and 60%, visible, and treatment group cure rate and total effective rate are obviously better than matched group.Through statistical procedures, between two groups of patient clinical curative effects, difference has statistical significance (P < 0.05).
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the scope of various embodiments of the present invention technical scheme.

Claims (10)

1. be used for the treatment of a Chinese medicine composition for chronic gastritis, it is characterized in that: the crude drug of described Chinese medicine composition is made up of Cortex Magnoliae Officinalis, Herba Dendrobii, Fructus Evodiae, Semen Raphani, Caulis Perillae, Endothelium Corneum Gigeriae Galli, the Rhizoma Pinelliae, Herba Selaginellae Uncinatae, Rhizoma Sparganii, Rhizoma Acori Graminei, Herba Pogostemonis, Fructus Piperis Longi, Fructus Hordei Germinatus, Radix Inulae, Fructus Amomi Rotundus, Rhizoma Corydalis, Pericarpium Citri Reticulatae, Flos Inulae, Semen Sinapis Albae, the Radix Linderae, Fructus Akebiae, Fructus Citri Sarcodactylis, Semen Aesculi, Caulis Polygoni Multiflori, Concha Ostreae (calcined), Herb Gynostemmae Pentaphylli, Herba Morindae Parvifoliae, Radix Et Caulis Acanthopanacis Senticosi, Semen Coicis, Rhizoma Imperatae, Folium Callicarpae Formosanae, Herba Patriniae, Fructus Mori.
2. the Chinese medicine composition being used for the treatment of chronic gastritis according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 12-17 part, Herba Dendrobii 7-12 part, Fructus Evodiae 4-9 part, Semen Raphani 15-20 part, Caulis Perillae 10-15 part, Endothelium Corneum Gigeriae Galli 8-12 part, Rhizoma Pinelliae 2-5 part, Herba Selaginellae Uncinatae 3-7 part, Rhizoma Sparganii 11-14 part, Rhizoma Acori Graminei 9-15 part, Herba Pogostemonis 3-6 part, Fructus Piperis Longi 8-13 part, Fructus Hordei Germinatus 3-5 part, Radix Inulae 1-3 part, Fructus Amomi Rotundus 3-6 part, Rhizoma Corydalis 8-13 part, Pericarpium Citri Reticulatae 3-5 part, Flos Inulae 11-15 part, Semen Sinapis Albae 5-10 part, Radix Linderae 2-5 part, Fructus Akebiae 4-9 part, Fructus Citri Sarcodactylis 12-20 part, Semen Aesculi 10-16 part, Caulis Polygoni Multiflori 3-8 part, Concha Ostreae (calcined) 5-12 part, Herb Gynostemmae Pentaphylli 5-10 part, Herba Morindae Parvifoliae 5-10 part, Radix Et Caulis Acanthopanacis Senticosi 13-16 part, Semen Coicis 3-10 part, Rhizoma Imperatae 8-13 part, Folium Callicarpae Formosanae 3-5 part, Herba Patriniae 1-3 part, Fructus Mori 5-10 part.
3. the Chinese medicine composition being used for the treatment of chronic gastritis according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 12 parts, Herba Dendrobii 10 parts, Fructus Evodiae 9 parts, Semen Raphani 15 parts, Caulis Perillae 15 parts, Endothelium Corneum Gigeriae Galli 8 parts, the Rhizoma Pinelliae 5 parts, Herba Selaginellae Uncinatae 3 parts, Rhizoma Sparganii 14 parts, Rhizoma Acori Graminei 9 parts, Herba Pogostemonis 6 parts, Fructus Piperis Longi 8 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 1 part, 6 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 8 parts, Pericarpium Citri Reticulatae 3 parts, Flos Inulae 15 parts, Semen Sinapis Albae 5 parts, the Radix Linderae 3 parts, Fructus Akebiae 5 parts, Fructus Citri Sarcodactylis 12 parts, Semen Aesculi 16 parts, Caulis Polygoni Multiflori 3 parts, Concha Ostreae (calcined) 12 parts, Herb Gynostemmae Pentaphylli 10 parts, Herba Morindae Parvifoliae 5 parts, Radix Et Caulis Acanthopanacis Senticosi 16 parts, Semen Coicis 10 parts, Rhizoma Imperatae 8 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 1 part, Fructus Mori 10 parts.
4. the Chinese medicine composition being used for the treatment of chronic gastritis according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 17 parts, Herba Dendrobii 12 parts, Fructus Evodiae 4 parts, Semen Raphani 20 parts, Caulis Perillae 10 parts, Endothelium Corneum Gigeriae Galli 12 parts, the Rhizoma Pinelliae 2 parts, Herba Selaginellae Uncinatae 7 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 15 parts, Herba Pogostemonis 3 parts, Fructus Piperis Longi 13 parts, Fructus Hordei Germinatus 3 parts, Radix Inulae 3 parts, 4 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 10 parts, Pericarpium Citri Reticulatae 4 parts, Flos Inulae 13 parts, Semen Sinapis Albae 6 parts, the Radix Linderae 4 parts, Fructus Akebiae 8 parts, Fructus Citri Sarcodactylis 20 parts, Semen Aesculi 10 parts, Caulis Polygoni Multiflori 8 parts, Concha Ostreae (calcined) 5 parts, Herb Gynostemmae Pentaphylli 5 parts, Herba Morindae Parvifoliae 10 parts, Radix Et Caulis Acanthopanacis Senticosi 13 parts, Semen Coicis 3 parts, Rhizoma Imperatae 13 parts, Folium Callicarpae Formosanae 3 parts, Herba Patriniae 3 parts, Fructus Mori 5 parts.
5. the Chinese medicine composition being used for the treatment of chronic gastritis according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 13 parts, Herba Dendrobii 7 parts, Fructus Evodiae 5 parts, Semen Raphani 18 parts, Caulis Perillae 11 parts, Endothelium Corneum Gigeriae Galli 9 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 6 parts, Rhizoma Sparganii 12 parts, Rhizoma Acori Graminei 13 parts, Herba Pogostemonis 4 parts, Fructus Piperis Longi 9 parts, Fructus Hordei Germinatus 4 parts, Radix Inulae 2 parts, 5 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 12 parts, Pericarpium Citri Reticulatae 3 parts, Flos Inulae 12 parts, Semen Sinapis Albae 9 parts, the Radix Linderae 4 parts, Fructus Akebiae 7 parts, Fructus Citri Sarcodactylis 13 parts, Semen Aesculi 11 parts, Caulis Polygoni Multiflori 4 parts, Concha Ostreae (calcined) 6 parts, Herb Gynostemmae Pentaphylli 6 parts, Herba Morindae Parvifoliae 6 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 5 parts, Rhizoma Imperatae 10 parts, Folium Callicarpae Formosanae 4 parts, Herba Patriniae 2 parts, Fructus Mori 6 parts.
6. the Chinese medicine composition being used for the treatment of chronic gastritis according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 16 parts, Herba Dendrobii 8 parts, Fructus Evodiae 8 parts, Semen Raphani 16 parts, Caulis Perillae 14 parts, Endothelium Corneum Gigeriae Galli 11 parts, the Rhizoma Pinelliae 3 parts, Herba Selaginellae Uncinatae 5 parts, Rhizoma Sparganii 13 parts, Rhizoma Acori Graminei 14 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 12 parts, Fructus Hordei Germinatus 3 parts, Radix Inulae 1 part, 4 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 11 parts, Pericarpium Citri Reticulatae 4 parts, Flos Inulae 14 parts, Semen Sinapis Albae 8 parts, the Radix Linderae 3 parts, Fructus Akebiae 6 parts, Fructus Citri Sarcodactylis 17 parts, Semen Aesculi 15 parts, Caulis Polygoni Multiflori 7 parts, Concha Ostreae (calcined) 11 parts, Herb Gynostemmae Pentaphylli 10 parts, Herba Morindae Parvifoliae 9 parts, Radix Et Caulis Acanthopanacis Senticosi 13 parts, Semen Coicis 7 parts, Rhizoma Imperatae 11 parts, Folium Callicarpae Formosanae 3 parts, Herba Patriniae 1 part, Fructus Mori 10 parts.
7. the Chinese medicine composition being used for the treatment of chronic gastritis according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 15 parts, Herba Dendrobii 9 parts, Fructus Evodiae 7 parts, Semen Raphani 19 parts, Caulis Perillae 13 parts, Endothelium Corneum Gigeriae Galli 10 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 4 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 11 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 10 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 3 parts, 6 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 9 parts, Pericarpium Citri Reticulatae 5 parts, Flos Inulae 12 parts, Semen Sinapis Albae 7 parts, the Radix Linderae 5 parts, Fructus Akebiae 9 parts, Fructus Citri Sarcodactylis 15 parts, Semen Aesculi 12 parts, Caulis Polygoni Multiflori 5 parts, Concha Ostreae (calcined) 9 parts, Herb Gynostemmae Pentaphylli 8 parts, Herba Morindae Parvifoliae 8 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 9 parts, Rhizoma Imperatae 12 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 3 parts, Fructus Mori 8 parts.
8. the Chinese medicine composition being used for the treatment of chronic gastritis according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Cortex Magnoliae Officinalis 14 parts, Herba Dendrobii 9 parts, Fructus Evodiae 6 parts, Semen Raphani 17 parts, Caulis Perillae 13 parts, Endothelium Corneum Gigeriae Galli 10 parts, the Rhizoma Pinelliae 4 parts, Herba Selaginellae Uncinatae 4 parts, Rhizoma Sparganii 11 parts, Rhizoma Acori Graminei 11 parts, Herba Pogostemonis 5 parts, Fructus Piperis Longi 10 parts, Fructus Hordei Germinatus 5 parts, Radix Inulae 3 parts, 3 parts, Fructus Amomi Rotundus, Rhizoma Corydalis 8 parts, Pericarpium Citri Reticulatae 5 parts, Flos Inulae 15 parts, Semen Sinapis Albae 7 parts, the Radix Linderae 2 parts, Fructus Akebiae 4 parts, Fructus Citri Sarcodactylis 19 parts, Semen Aesculi 14 parts, Caulis Polygoni Multiflori 6 parts, Concha Ostreae (calcined) 7 parts, Herb Gynostemmae Pentaphylli 8 parts, Herba Morindae Parvifoliae 8 parts, Radix Et Caulis Acanthopanacis Senticosi 14 parts, Semen Coicis 4 parts, Rhizoma Imperatae 9 parts, Folium Callicarpae Formosanae 5 parts, Herba Patriniae 3 parts, Fructus Mori 8 parts.
9. the arbitrary described Chinese medicine composition being used for the treatment of chronic gastritis of claim 3-8, is characterized in that, be prepared in accordance with the following steps:
(1) each medical material is got according to components by weight percent, pulverized by pulverizer after mixing, obtaining medicated powder fineness is 80-120 object mixture, and it is 95% alcohol reflux 2 times that mixture adds determining alcohol, first time adds the ethanol relative to this mixture quality 8 times amount, refluxes 2 hours; Second time adds the ethanol relative to this mixture quality 7 times amount, refluxes 1 hour, filters; Merge 2 filtrates, being evaporated to temperature is that at 60 DEG C, relative density is the thick paste of 1.10 ~ 1.13, for subsequent use; Volatilize ethanol simultaneously, and medicinal residues are continued to employ;
(2) medicinal residues that ethanol extraction in step (1) is crossed are decocted with water twice; First time adds the water relative to this mixture 8 times amount, decocts 2 hours, and second time adds the water relative to this mixture 7 times amount, decocts 1 hour, filters; Merge 2 filtrates, be evaporated to the thick paste that temperature is relative density 1.10 ~ 1.12 at 60 DEG C, for subsequent use;
(3) step (1), (2) concentrated thick paste obtained are merged, mixing, be evaporated to that temperature is 60 DEG C, the clear paste of relative density 1.30 ~ 1.32 further, after dry, pulverize subsequently, make 80 order fine powders;
(4) by the 80 order fine powders that step (3) is obtained, after adding suitable amount of sucrose, dextrin mixing, take ethanol as wetting agent, granulate, dry, granulate, can obtain granule; Or after 80 obtained for step (3) order fine powder packagings, make powder; Or the 80 order fine powders that step (3) is obtained are added appropriate micropowder silica gel, α-galactose mixing, take ethanol as wetting agent, granulate, dry, granulate, encapsulated, obtained capsule; Or the 80 order fine powders that step (3) is obtained are added suitable amount of sucrose, dextrin mixing, take ethanol as wetting agent, granulate, dry, granulate, tabletting, obtained tablet.
10. the application of the Chinese medicine composition being used for the treatment of chronic gastritis as described in as arbitrary in claim 1-9 in treatment chronic gastritis medicine.
CN201510727183.1A 2015-10-30 2015-10-30 Traditional Chinese medicine composition for treating chronic gastritis Pending CN105169212A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395953A (en) * 2015-12-29 2016-03-16 赵红 Traditional Chinese medicine for treating chronic gastritis
CN105412542A (en) * 2015-12-31 2016-03-23 青岛昌安达药业有限公司 Traditional Chinese medicine preparation used for treating chronic gastritis
CN105412543A (en) * 2015-12-31 2016-03-23 青岛昌安达药业有限公司 Traditional Chinese medicine composition used for treating chronic gastritis
CN105797119A (en) * 2016-05-03 2016-07-27 刘春梅 Traditional Chinese medicine composition for treating chronic gastritis and preparation method thereof
CN107027932A (en) * 2017-04-20 2017-08-11 四川同兴天然植物药业有限公司 It is a kind of that there is the red sage compound tea for improving chronic gastritis effect

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137384A (en) * 1995-06-02 1996-12-11 周国华 Changweiling medicine for curing enterogastritis
CN104524283A (en) * 2014-12-22 2015-04-22 广东聚智诚科技有限公司 Use of traditional Chinese medicine composition for preparing medicine for treating chronic gastritis
CN104667126A (en) * 2015-02-15 2015-06-03 柳晖 Traditional Chinese medicinal composition for treating chronic gastritis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137384A (en) * 1995-06-02 1996-12-11 周国华 Changweiling medicine for curing enterogastritis
CN104524283A (en) * 2014-12-22 2015-04-22 广东聚智诚科技有限公司 Use of traditional Chinese medicine composition for preparing medicine for treating chronic gastritis
CN104667126A (en) * 2015-02-15 2015-06-03 柳晖 Traditional Chinese medicinal composition for treating chronic gastritis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395953A (en) * 2015-12-29 2016-03-16 赵红 Traditional Chinese medicine for treating chronic gastritis
CN105412542A (en) * 2015-12-31 2016-03-23 青岛昌安达药业有限公司 Traditional Chinese medicine preparation used for treating chronic gastritis
CN105412543A (en) * 2015-12-31 2016-03-23 青岛昌安达药业有限公司 Traditional Chinese medicine composition used for treating chronic gastritis
CN105797119A (en) * 2016-05-03 2016-07-27 刘春梅 Traditional Chinese medicine composition for treating chronic gastritis and preparation method thereof
CN107027932A (en) * 2017-04-20 2017-08-11 四川同兴天然植物药业有限公司 It is a kind of that there is the red sage compound tea for improving chronic gastritis effect

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Application publication date: 20151223