CN105165870A - Synergistic herbicide composition - Google Patents
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Abstract
Description
本申请是申请号为201410200173.8，申请日为2013年7月3日，发明名称为“增效除草组合物”的分案申请。 This application is a divisional application with the application number 201410200173.8, the application date is July 3, 2013, and the invention title is "Synergistic Herbicidal Composition".
技术领域 technical field
本发明涉及的是一种复配增效除草组合物，尤其涉及一种应用抗性油菜、抗性大豆作物等田间的增效除草组合物。 The invention relates to a compound synergistic herbicidal composition, in particular to a synergistic herbicidal composition applied to fields such as resistant rapeseed and resistant soybean crops.
背景技术 Background technique
芳氧基苯氧基丙酸酯类除草剂是自20世纪70年代才开发的一类防除禾本科杂草的新型除草剂，如高效氟吡甲禾灵（Haloxyfop-R-methyl）、精噁唑禾草灵(Fenoxaprop-P-ethyl)、精吡氟禾草灵(Fluazifop-P-butyl)和精喹禾灵(Quizalofop-p-ethyl)等，是在研究苯氧乙酸类除草剂的基础上发展起来的，它具有许多优异的特性。这类除草剂的作用靶标是乙酰辅酶A羧化酶，抑制脂肪酸生物合成，干扰代谢作用，主要是破坏细胞膜结构和抑制分生组织的细胞分裂以及破坏叶绿体。光合作用及同化物质运输受阻，生长受抑制，进而植株死亡。这类除草剂不仅在阔叶与禾本科植物间具有良好的选择性，在禾本科植物内也有良好的属间选择性，因而也可用于麦田除草。这类除草剂各品种的适用作物及杀草谱差异不大，几乎对所有的阔叶作物都安全。其次，这类除草剂为内吸传导型除草剂，可通过茎、叶、根被植物吸收，并传导全株。用于土壤处理时对根有较强的抑制使用。用于茎叶处理时对幼芽的抑制作用更强。因而以杂草幼龄期叶面喷雾的除草效果为佳。此外，这类除草剂还是植物激素的拮抗剂，因而影响植物体内广泛的生理、生化过程。使用时不能与激素型苯氧乙酸类除草剂2，4一滴丁酯、2甲4氯等混用或连用。 Aryloxyphenoxypropionate herbicides are a new type of herbicides developed since the 1970s to control grass weeds, such as Haloxyfop-R-methyl, Jing Fenoxaprop-P-ethyl, Fluazifop-P-butyl and Quizalofop-p-ethyl are the basis for research on phenoxyacetic acid herbicides Developed on , it has many excellent characteristics. The target of this type of herbicide is acetyl-CoA carboxylase, which inhibits fatty acid biosynthesis, interferes with metabolism, mainly destroys cell membrane structure, inhibits meristem cell division and destroys chloroplast. Photosynthesis and transport of assimilated substances are hindered, growth is inhibited, and the plants die. This kind of herbicide not only has good selectivity between broadleaf and gramineous plants, but also has good intergeneric selectivity within gramineous plants, so it can also be used for weeding in wheat fields. The applicable crops and herbicidal spectrum of each variety of this herbicide have little difference, and they are safe to almost all broad-leaved crops. Secondly, this type of herbicide is a systemic herbicide, which can be absorbed by plants through stems, leaves, and roots, and transmitted to the whole plant. When used in soil treatment, it has a strong inhibitory effect on roots. The inhibitory effect on young shoots is stronger when it is used for stem and leaf treatment. Therefore, the weeding effect of the weed young stage foliar spray is the best. In addition, these herbicides are antagonists of plant hormones, thus affecting a wide range of physiological and biochemical processes in plants. When used, it cannot be mixed or used together with hormone-type phenoxyacetic acid herbicides such as 2,4-butyl ester, 2-methyl-4-chlorine, etc.
此类除草剂的原药均为酯类化合物，被植物吸收以后，其酯键在细胞内通过酯酶。特别是396羧酸酯酶的诱导被水解为酸。而酸对作用靶标乙酰辅酶A羧化酶的抑制作用(即杀草能力)显著大于酯，因而原药酯易于水解的品种具有更高的除草活性。 The original drugs of these herbicides are all ester compounds. After being absorbed by plants, their ester bonds pass through esterases in the cells. In particular the induction of 396 carboxylesterase is hydrolyzed to acid. However, the inhibitory effect of acid on the target acetyl-CoA carboxylase (that is, the herbicidal ability) is significantly greater than that of esters, so the varieties of the original drug esters that are easy to hydrolyze have higher herbicidal activity.
磺酰脲类除草剂品种的开发始于70年代末期。1978年Levitt等报道,氯磺隆(chlorsulfuron)以极低用量进行苗前土壤处理或苗后茎叶处理,可有效地防治麦类与亚麻田大多数杂草。紧接着开发出甲磺隆(Metsulfuron-methyl)，随后又开发出甲嘧磺隆、氯嘧磺隆、苯磺隆、噻吩磺隆、苄嘧磺隆等一系列品种。此类除草剂发展极快，已在各种作物地使用，有些已成为一些作物田的当家除草剂品种。而且，新的品种还在不断地商品化。磺酰脲类除草剂由芳香基、磺酰脲桥和杂环三部分组成。其基本化学结构式为：在每一组分上取代基的微小变化都会导致生物活性和选择性的极大变化。其主要包括的产品有：噻吩磺隆(Thifensulfuron-methyl)，化学名称叫3-(4-甲氧基-6-甲基-1,3,5-三嗪-2-基)-1-(2-甲氧基甲酰基噻吩-3-基)-磺酰脲；苯磺隆(Tribenuron-methyl)，化学名称叫2-[N-(4-甲氧基-6-甲基-1,3,5-三嗪-2-基)-N-甲基氨基甲酰胺基磺酰基]苯甲酸甲酯；环丙嘧磺隆(Cyclosulfamuron)，化学名称叫1-{[O-(环丙酰基)苯基]氨磺酰}-3(4,6-二甲氧基-2-吡啶基)-脲；苄嘧磺隆(Bensulfuron-methyl)，化学名称叫2-{((4,6-二甲氧基嘧啶-2-基)氨基羰基氮基]磺酰基甲基)苯甲酸甲酯；醚苯磺隆，化学名称叫1-[2-(2-氯乙氧基)苯基磺酰基]-3-(4-甲氧基-6-甲基-1,3,5-三嗪-2-基)脲；甲基二磺隆(Mesosulfuron-methyl)，化学名称叫甲基-2[3-(4，6-=甲氧基嘧啶-2-基)一脲基磺酰基l-4-甲磺酰基氨基苯甲酸酯；单嘧磺隆(Monosulfuron)，化学名称叫2-(4-甲基嘧啶基)苯磺酰脲；酰嘧磺隆(Amidosulfuron)，化学名称叫1-(4,6-二甲氧基-2-嘧啶基)-3-(N-甲基甲磺酰胺磺酰基)-脲氨基嘧黄隆；甲磺隆(Metsulfuron-methyl)，化学名称叫2-[(4-甲氧基-6-甲基-1,3,5-三嗪基-2-基)脲基磺酰基]苯甲酸甲酯；氯磺隆(Chlorsulfuron)，化学名称叫1-(2-氯苯基磺酰)3-(4-甲氧基-6-甲基-1,3,5-三嗪-2-基)脲；烟嘧磺隆(Nicosulfuron)，化学名称叫2-（4,6-二甲氧基嘧啶-2-基氨基甲酰氨基磺酰）-N,N-二甲基烟酰胺。 The development of sulfonylurea herbicide varieties began in the late 1970s. In 1978, Levitt reported that chlorsulfuron could effectively control most weeds in wheat and flax fields by pre-emergence soil treatment or post-emergence stem and leaf treatment at very low dosage. Then metsulfuron-methyl was developed, followed by a series of varieties such as metsulfuron-methyl, chlorimuron-methyl, tribenuron-methyl, thifensulfuron-methyl, and bensulfuron-methyl. This kind of herbicide has developed very fast and has been used in various crop fields, and some have become the main herbicide varieties in some crop fields. Moreover, new varieties are constantly being commercialized. Sulfonylurea herbicides are composed of three parts: aromatic group, sulfonylurea bridge and heterocycle. Its basic chemical structure formula is: small changes in substituents on each component will lead to great changes in biological activity and selectivity. Its main products include: Thifensulfuron-methyl, the chemical name is 3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-1-( 2-methoxyformylthiophen-3-yl)-sulfonylurea; Tribenuron-methyl, the chemical name is 2-[N-(4-methoxy-6-methyl-1,3 ,5-triazin-2-yl)-N-methylcarbamoylsulfonyl]methyl benzoate; Cyclosulfamuron (Cyclosulfamuron), the chemical name is 1-{[O-(cyclopropionyl) Phenyl]sulfamoyl}-3(4,6-dimethoxy-2-pyridyl)-urea; Bensulfuron-methyl (Bensulfuron-methyl), the chemical name is 2-{((4,6-di Methoxypyrimidin-2-yl)aminocarbonylnitro]sulfonylmethyl)methyl benzoate; Tribesulfuron-methyl, chemical name is 1-[2-(2-chloroethoxy)phenylsulfonyl] -3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea; Mesosulfuron-methyl, the chemical name is methyl-2[3 -(4,6-=Methoxypyrimidin-2-yl)-ureidosulfonyl l-4-methylsulfonylaminobenzoate; Monosulfuron (Monosulfuron), chemical name is 2-(4- Methylpyrimidinyl) benzenesulfonylurea; Amidosulfuron (Amidosulfuron), the chemical name is 1-(4,6-dimethoxy-2-pyrimidinyl)-3-(N-methylmethanesulfonamide sulfonamide Acyl)-carbazone rimsulfuron; Metsulfuron-methyl, the chemical name is 2-[(4-methoxy-6-methyl-1,3,5-triazinyl-2-yl) Ureadosulfonyl] methyl benzoate; Chlorsulfuron (Chlorsulfuron), the chemical name is 1-(2-chlorophenylsulfonyl) 3-(4-methoxy-6-methyl-1,3,5 -Triazin-2-yl)urea; Nicosulfuron (Nicosulfuron), the chemical name is 2-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-N,N-di Methylnicotinamide.
发明内容 Contents of the invention
本发明目的是针对上述不足之处提供一种增效除草组合物，能够一次性的防除田间所有的杂草，扩大芳氧基苯氧基丙酸酯类除草剂和磺酰脲类除草剂的杀草谱的限制，提高芳氧基苯氧基丙酸酯类除草剂和磺酰脲类除草剂对双子叶和单子叶杂草的杀草速度，本发明提供一种增效除草组合物，该组合物将特定的芳氧基苯氧基丙酸酯类除草剂和磺酰脲类除草剂进行复配。本发明惊异的发现，得到的组合物在抗性油菜、抗性大豆作物田杂草上取得了增益效果，显著降低杂草防治所需活性成分的量，而且对作物的植物毒性没有产生无法接受的毒性。 The object of the present invention is to provide a kind of synergistic herbicide composition for above-mentioned deficiencies, can one-time control and eliminate all weeds in the field, expand the use of aryloxyphenoxypropionate herbicides and sulfonylurea herbicides. The limitation of herbicidal spectrum improves the herbicidal speed of aryloxyphenoxypropionate herbicides and sulfonylurea herbicides on dicotyledonous and monocotyledonous weeds. The present invention provides a synergistic herbicidal composition, The composition compounded specific aryloxyphenoxypropionate herbicides and sulfonylurea herbicides. Surprisingly found by the present invention, the obtained composition achieves a beneficial effect on weeds in resistant rapeseed and resistant soybean crops, significantly reduces the amount of active ingredients required for weed control, and does not cause unacceptable phytotoxicity to crops toxicity.
为了解决上述技术问题，本发明提供了一种增效除草组合物，该组合物通过二元复配，使得所得到的新组合物抗性油菜、抗性大豆等田间的单子叶杂草、双子叶杂草防除上取得了增益的效果，且对后茬作物安全。 In order to solve the above-mentioned technical problems, the present invention provides a synergistic herbicidal composition, which makes the obtained new composition resistant to rapeseed, resistant soybean and other field monocotyledonous weeds, dicotyledonous weeds, etc. Gained effect on the control of leaf weeds, and it is safe for subsequent crops.
本发明解决其技术问题所采用的技术方案为： The technical scheme that the present invention solves its technical problem adopts is:
一种增效除草组合物，包括化合物A和化合物B，化合物A选自高效氟吡甲禾灵、精噁唑禾草灵、精吡氟禾草灵和精喹禾灵中的一种；化合物B选自噻吩磺隆、苯磺隆、环丙嘧磺隆、苄嘧磺隆、醚苯磺隆、甲基二磺隆、单嘧磺隆、酰嘧磺隆、甲磺隆、氯磺隆、烟嘧磺隆中的一种；化合物A和化合B的重量配比范围为100:1至1：100，优选50:1至1:50,更优选10:1至1:10。 A synergistic herbicidal composition, including compound A and compound B, compound A is selected from one of high-efficiency haloxyfop-p-p, oxaprop-p-p-p, fluazifop-p-p-p and quizalof-p-p-p; B is selected from thifensulfuron-methyl, tribenuron-methyl, cyprosulfuron-methyl, bensulfuron-methyl, ethensulfuron-methyl, methylsulfuron-methyl, monosulfuron-methyl, rimsulfuron-methyl, metsulfuron-methyl, chlorsulfuron-methyl , one of nicosulfuron; the weight ratio of compound A and compound B is in the range of 100:1 to 1:100, preferably 50:1 to 1:50, more preferably 10:1 to 1:10.
本发明的增效除草组合物的组合方式可以是 The combination mode of the synergistic herbicidal composition of the present invention can be
（1）高效氟吡甲禾灵+噻吩磺隆； (1) High-efficiency flurifop-methyl + thifensulfuron-methyl;
（2）高效氟吡甲禾灵+苯磺隆； (2) High-efficiency haloxyfop-methyl + tribenuron-methyl;
（3）高效氟吡甲禾灵+环丙嘧磺隆； (3) High-efficiency haloxyfop-methyl + cyprosulfuron-methyl;
（4）高效氟吡甲禾灵+苄嘧磺隆； (4) High-efficiency flurifop-methyl + bensulfuron-methyl;
（5）高效氟吡甲禾灵+醚苯磺隆； (5) High-efficiency flurifop-methyl + tribenuron-methyl;
（6）高效氟吡甲禾灵+甲基二磺隆； (6) High-efficiency flurifop-pyl + methylsulfuron-methyl;
（7）高效氟吡甲禾灵+单嘧磺隆； (7) High-efficiency haloxyfop-methyl + monosulfuron-methyl;
（8）高效氟吡甲禾灵+酰嘧磺隆； (8) High-efficiency flurifop-methyl + sulfuron-methyl;
（9）高效氟吡甲禾灵+甲磺隆； (9) High-efficiency haloxyfop-methyl + metsulfuron-methyl;
（10）高效氟吡甲禾灵+氯磺隆； (10) High-efficiency flurifop-methyl + chlorsulfuron;
（11）高效氟吡甲禾灵+烟嘧磺隆； (11) High-efficiency haloxyfop-methyl + nicosulfuron;
（12）精噁唑禾草灵+噻吩磺隆； (12) Fenoxaprop-ethyl + thifensulfuron-methyl;
（13）精噁唑禾草灵+苯磺隆； (13) Fenoxaprop-ethyl + tribenuron-methyl;
（14）精噁唑禾草灵+环丙嘧磺隆； (14) Fenoxaprop-ethyl + cyprosulfuron-methyl;
（15）精噁唑禾草灵+苄嘧磺隆； (15) Fenoxaprop-ethyl + bensulfuron-methyl;
（16）精噁唑禾草灵+醚苯磺隆； (16) Fenoxaprop-ethyl + tribesulfuron-methyl;
（17）精噁唑禾草灵+甲基二磺隆； (17) Fenoxaprop-ethyl + methylsulfuron-methyl;
（18）精噁唑禾草灵+单嘧磺隆； (18) Fenoxaprop-ethyl + monosulfuron-methyl;
（19）精噁唑禾草灵+酰嘧磺隆； (19) Fenoxaprop-ethyl + acylsulfuron-methyl;
（20）精噁唑禾草灵+甲磺隆； (20) Fenoxaprop-ethyl + metsulfuron-methyl;
（21）精噁唑禾草灵+氯磺隆； (21) Fenoxaprop-ethyl + chlorsulfuron-methyl;
（22）精噁唑禾草灵+烟嘧磺隆； (22) Fenoxaprop-ethyl + Nicosulfuron-methyl;
（23）精吡氟禾草灵+噻吩磺隆； (23) Fluazifop-ethyl + thifensulfuron-methyl;
（24）精吡氟禾草灵+苯磺隆； (24) Fluazifop-ethyl + Tribesulfuron-methyl;
（25）精吡氟禾草灵+环丙嘧磺隆； (25) Fluazifop-ethyl + Cyprosulfuron-methyl;
（26）精吡氟禾草灵+苄嘧磺隆； (26) Fluazifop-ethyl + bensulfuron-methyl;
（27）精吡氟禾草灵+醚苯磺隆； (27) Refined fluazifop-methyl + tribenuron-methyl;
（28）精吡氟禾草灵+甲基二磺隆； (28) Fluazifop-methyl + methylsulfuron-methyl;
（29）精吡氟禾草灵+单嘧磺隆； (29) Fluazifop-ethyl + monosulfuron-methyl;
（30）精吡氟禾草灵+酰嘧磺隆； (30) Fluazifop-ethyl + sulfuron-methyl;
（31）精吡氟禾草灵+甲磺隆； (31) Fluazifop-ethyl + metsulfuron-methyl;
（32）精吡氟禾草灵+氯磺隆； (32) Fluazifop-ethyl + Chlorsulfuron-methyl;
（33）精吡氟禾草灵+烟嘧磺隆； (33) Fluazifop-ethyl + Nicosulfuron-methyl;
（34）精喹禾灵+噻吩磺隆； (34) Quizalofop-ethyl + Thifensulfuron-methyl;
（35）精喹禾灵+苯磺隆； (35) Quizalofop-ethyl + tribenuron-methyl;
（36）精喹禾灵+环丙嘧磺隆； (36) Quizalofop-ethyl + Cyprosulfuron-methyl;
（37）精喹禾灵+苄嘧磺隆； (37) Quizalofop-ethyl + bensulfuron-methyl;
（38）精喹禾灵+醚苯磺隆； (38) Quizalofop-ethyl + tribenuron-methyl;
（39）精喹禾灵+甲基二磺隆； (39) Quizalofop-ethyl + methylsulfuron-methyl;
（40）精喹禾灵+单嘧磺隆； (40) Quizalofop-ethyl + monosulfuron-methyl;
（41）精喹禾灵+酰嘧磺隆； (41) Quizalofop-ethyl + sulfuron-methyl;
（42）精喹禾灵+甲磺隆； (42) Quizalofop-ethyl + metsulfuron-methyl;
（43）精喹禾灵+氯磺隆； (43) Quizalofop-ethyl + Chlorsulfuron;
（44）精喹禾灵+烟嘧磺隆。 (44) Quizalofop-ethyl + Nicosulfuron.
所述增效除草组合物可配制成农业上允许的任意剂型，优选可湿性粉剂、乳油、悬浮剂、油悬浮剂、微囊剂、微乳剂、水乳剂、悬浮乳剂、水分散粒剂、ZC、超低容量液剂。 The synergistic herbicidal composition can be formulated into any dosage form allowed in agriculture, preferably wettable powder, emulsifiable concentrate, suspension concentrate, oil suspension concentrate, microcapsule, microemulsion, water emulsion, suspoemulsion, water dispersible granule, ZC , Ultra-low volume liquid.
本发明还提供一种增效除草组合物，包含所述有效量的活性化合物组合与至少一种制剂技术常用助剂混合。 The present invention also provides a synergistic herbicidal composition comprising said effective amount of active compound combination mixed with at least one adjuvant commonly used in formulation technology.
本发明还提供一种防治不希望有的植物的方法，包括将所述的增效除草组合物在苗前、苗后、或苗前和苗后施用至植物、植物各组织、植物种子上或栽培区域。所述不希望有的植物为单子叶杂草、双子叶杂草。 The present invention also provides a method for controlling unwanted plants, comprising applying said synergistic herbicidal composition to plants, plant tissues, plant seeds or cultivation area. Said undesired plants are monocotyledonous weeds, dicotyledonous weeds.
不希望有的植物如繁缕属、豆瓣菜属、剪股颖属、马唐属、燕麦属、狗尾草属、欧白芥属、黑麦草属、茄属、雀麦属、看麦娘属、母菊属、茼麻属、黄花稔属、苍耳属、苋属、藜属、番薯属、茼蒿属、猪殃殃属、堇菜属和婆婆纳属。 Undesirable plants such as chickweed, watercress, bentgrass, crabgrass, oats, foxtail, white mustard, ryegrass, nightshade, brome, aleuria, Matricaria, Chrysanthemum, Chrysanthemum, Cocklebur, Amaranthus, Chenopodium, Ipomoea batatas, Chrysanthemum chrysanthemum, Sorrelia, Viola, and Possum.
本发明还涉及一种控制抗磺酰脲油菜、大豆作物中不需要的植物生长的方法，其中包括将化合物（A）中的至少一种和化合物(B)中的至少一种施用至有害植物，其各种组织或栽培区域。 The present invention also relates to a method of controlling unwanted vegetation in sulfonylurea-resistant rapeseed, soybean crops, which comprises applying at least one of compounds (A) and at least one of compounds (B) to harmful plants , its various tissues or areas of cultivation.
本发明还涉及化合物（A）+(B)的除草组合物，以及包含它们的除草剂组合物。 The present invention also relates to herbicidal compositions of compounds (A)+(B), and herbicidal compositions comprising them.
本发明一种增效除草组合物，能够一次性的防除田间所有的杂草，扩大芳氧基苯氧基丙酸酯类除草剂和磺酰脲类除草剂的杀草谱的限制，提高芳氧基苯氧基丙酸酯类除草剂和磺酰脲类除草剂对双子叶和单子叶杂草的杀草速度，本发明提供一种增效除草组合物，该组合物将特定的芳氧基苯氧基丙酸酯类除草剂和磺酰脲类除草剂进行复配。本发明惊异的发现，得到的组合物在抗性油菜、抗性大豆作物田杂草上取得了增益效果，显著降低杂草防治所需活性成分的量，而且对作物的植物毒性没有产生无法接受的毒性。 A synergistic herbicidal composition of the present invention can control and eliminate all weeds in the field at one time, expand the limitation of the herbicidal spectrum of aryloxyphenoxypropionate herbicides and sulfonylurea herbicides, and increase the The herbicide speed of oxyphenoxypropionate herbicides and sulfonylurea herbicides to dicotyledonous and monocotyledonous weeds, the present invention provides a kind of synergistic herbicidal composition, and this composition will specific aromatic oxygen It is compounded with phenoxypropionate herbicides and sulfonylurea herbicides. Surprisingly found by the present invention, the obtained composition achieves a beneficial effect on weeds in resistant rapeseed and resistant soybean crops, significantly reduces the amount of active ingredients required for weed control, and does not cause unacceptable phytotoxicity to crops toxicity.
本发明提供了一种增效除草组合物，该组合物通过二元复配，使得所得到的新组合物抗性油菜、抗性大豆等田间的单子叶杂草、双子叶杂草防除上取得了协同增益的效果，且对后茬作物安全。 The present invention provides a synergistic herbicidal composition, the composition through binary compounding, so that the obtained new composition resistant rapeseed, resistant soybean and other fields of monocotyledonous weeds, dicotyledonous weeds can be effectively controlled The effect of synergistic gain is achieved, and it is safe for subsequent crops.
具体实施方式 Detailed ways
将不同农药的有效成分组合制成农药，是目前开发和研制新农药以及防治农业上恶性杂草的一种有效和快捷的方式。不同品种的农药混合后，通常表现出三种作用类型：相加作用、增效作用和拮抗作用。但具体为何种作用，无法预测，只有通过大量实验才能知道。复配增效是很好的配方，由于明显提高了实际防治效果，降低了农药的使用量，从而大大地延缓了抗药性的产生速度，是有效除草的重要手段。 Combining the active ingredients of different pesticides to make pesticides is an effective and fast way to develop and develop new pesticides and prevent and control malignant weeds in agriculture. When pesticides of different varieties are mixed, they usually show three types of effects: additive effect, synergistic effect and antagonistic effect. However, it is impossible to predict the specific role, and it can only be known through a large number of experiments. Compounding and synergizing is a very good formula, because it significantly improves the actual control effect and reduces the use of pesticides, thereby greatly delaying the emergence of drug resistance, and is an important means of effective weeding.
一种增效除草组合物，包括化合物A和化合物B，化合物A选自高效氟吡甲禾灵、精噁唑禾草灵、精吡氟禾草灵和精喹禾灵中的一种；化合物B选自噻吩磺隆、苯磺隆、环丙嘧磺隆、苄嘧磺隆、醚苯磺隆、甲基二磺隆、单嘧磺隆、酰嘧磺隆、甲磺隆、氯磺隆、烟嘧磺隆中的一种；化合物A和化合B的重量配比范围为100:1至1：100，优选50:1至1:50,更优选20:1至1:20。 A synergistic herbicidal composition, including compound A and compound B, compound A is selected from one of high-efficiency haloxyfop-p-p, oxaprop-p-p-p, fluazifop-p-p-p and quizalof-p-p-p; B is selected from thifensulfuron-methyl, tribenuron-methyl, cyprosulfuron-methyl, bensulfuron-methyl, ethensulfuron-methyl, methylsulfuron-methyl, monosulfuron-methyl, rimsulfuron-methyl, metsulfuron-methyl, chlorsulfuron-methyl , one of nicosulfuron; the weight ratio of compound A and compound B is in the range of 100:1 to 1:100, preferably 50:1 to 1:50, more preferably 20:1 to 1:20.
本发明的增效除草组合物的组合方式可以是 The combination mode of the synergistic herbicidal composition of the present invention can be
（1）高效氟吡甲禾灵+噻吩磺隆； (1) High-efficiency flurifop-methyl + thifensulfuron-methyl;
（2）高效氟吡甲禾灵+苯磺隆； (2) High-efficiency haloxyfop-methyl + tribenuron-methyl;
（3）高效氟吡甲禾灵+环丙嘧磺隆； (3) High-efficiency haloxyfop-methyl + cyprosulfuron-methyl;
（4）高效氟吡甲禾灵+苄嘧磺隆； (4) High-efficiency flurifop-methyl + bensulfuron-methyl;
（5）高效氟吡甲禾灵+醚苯磺隆； (5) High-efficiency flurifop-methyl + tribenuron-methyl;
（6）高效氟吡甲禾灵+甲基二磺隆； (6) High-efficiency flurifop-pyl + methylsulfuron-methyl;
（7）高效氟吡甲禾灵+单嘧磺隆； (7) High-efficiency haloxyfop-methyl + monosulfuron-methyl;
（8）高效氟吡甲禾灵+酰嘧磺隆； (8) High-efficiency flurifop-methyl + sulfuron-methyl;
（9）高效氟吡甲禾灵+甲磺隆； (9) High-efficiency haloxyfop-methyl + metsulfuron-methyl;
（10）高效氟吡甲禾灵+氯磺隆； (10) High-efficiency flurifop-methyl + chlorsulfuron;
（11）高效氟吡甲禾灵+烟嘧磺隆； (11) High-efficiency haloxyfop-methyl + nicosulfuron;
（12）精噁唑禾草灵+噻吩磺隆； (12) Fenoxaprop-ethyl + thifensulfuron-methyl;
（13）精噁唑禾草灵+苯磺隆； (13) Fenoxaprop-ethyl + tribenuron-methyl;
（14）精噁唑禾草灵+环丙嘧磺隆； (14) Fenoxaprop-ethyl + cyprosulfuron-methyl;
（15）精噁唑禾草灵+苄嘧磺隆； (15) Fenoxaprop-ethyl + bensulfuron-methyl;
（16）精噁唑禾草灵+醚苯磺隆； (16) Fenoxaprop-ethyl + tribesulfuron-methyl;
（17）精噁唑禾草灵+甲基二磺隆； (17) Fenoxaprop-ethyl + methylsulfuron-methyl;
（18）精噁唑禾草灵+单嘧磺隆； (18) Fenoxaprop-ethyl + monosulfuron-methyl;
（19）精噁唑禾草灵+酰嘧磺隆； (19) Fenoxaprop-ethyl + acylsulfuron-methyl;
（20）精噁唑禾草灵+甲磺隆； (20) Fenoxaprop-ethyl + metsulfuron-methyl;
（21）精噁唑禾草灵+氯磺隆； (21) Fenoxaprop-ethyl + chlorsulfuron-methyl;
（22）精噁唑禾草灵+烟嘧磺隆； (22) Fenoxaprop-ethyl + Nicosulfuron-methyl;
（23）精吡氟禾草灵+噻吩磺隆； (23) Fluazifop-ethyl + thifensulfuron-methyl;
（24）精吡氟禾草灵+苯磺隆； (24) Fluazifop-ethyl + Tribesulfuron-methyl;
（25）精吡氟禾草灵+环丙嘧磺隆； (25) Fluazifop-ethyl + Cyprosulfuron-methyl;
（26）精吡氟禾草灵+苄嘧磺隆； (26) Fluazifop-ethyl + bensulfuron-methyl;
（27）精吡氟禾草灵+醚苯磺隆； (27) Refined fluazifop-methyl + tribenuron-methyl;
（28）精吡氟禾草灵+甲基二磺隆； (28) Fluazifop-methyl + methylsulfuron-methyl;
（29）精吡氟禾草灵+单嘧磺隆； (29) Fluazifop-ethyl + monosulfuron-methyl;
（30）精吡氟禾草灵+酰嘧磺隆； (30) Fluazifop-ethyl + sulfuron-methyl;
（31）精吡氟禾草灵+甲磺隆； (31) Fluazifop-ethyl + metsulfuron-methyl;
（32）精吡氟禾草灵+氯磺隆； (32) Fluazifop-ethyl + Chlorsulfuron-methyl;
（33）精吡氟禾草灵+烟嘧磺隆； (33) Fluazifop-ethyl + Nicosulfuron-methyl;
（34）精喹禾灵+噻吩磺隆； (34) Quizalofop-ethyl + Thifensulfuron-methyl;
（35）精喹禾灵+苯磺隆； (35) Quizalofop-ethyl + tribenuron-methyl;
（36）精喹禾灵+环丙嘧磺隆； (36) Quizalofop-ethyl + Cyprosulfuron-methyl;
（37）精喹禾灵+苄嘧磺隆； (37) Quizalofop-ethyl + bensulfuron-methyl;
（38）精喹禾灵+醚苯磺隆； (38) Quizalofop-ethyl + tribenuron-methyl;
（39）精喹禾灵+甲基二磺隆； (39) Quizalofop-ethyl + methylsulfuron-methyl;
（40）精喹禾灵+单嘧磺隆； (40) Quizalofop-ethyl + monosulfuron-methyl;
（41）精喹禾灵+酰嘧磺隆； (41) Quizalofop-ethyl + sulfuron-methyl;
（42）精喹禾灵+甲磺隆； (42) Quizalofop-ethyl + metsulfuron-methyl;
（43）精喹禾灵+氯磺隆； (43) Quizalofop-ethyl + Chlorsulfuron;
（44）精喹禾灵+烟嘧磺隆。 (44) Quizalofop-ethyl + Nicosulfuron.
所述特定的化合物A和化合物B组合超过了原则上预期的对欲防治杂草的加和作用，因此特别是在下述两方面拓宽了两种活性成分的作用范围：首先，降低了单个化合物的用量，同时保持了良好的作用水平；其次，在单个物质在低用量范围下从农业的观点上看变得无效的情况下，本发明组合物也能获得高的杂草防治水平。结果是显著拓宽了杂草谱，另外增加了对有益植物作物的选择性，这正是在无意过量使用活性成分的情况下所需要和期望的。本发明组合物在保持很好地防治有益植物中的杂草的同时，还对后茬作物有较大的适应性。 The specific combination of compound A and compound B exceeds the additive effect expected in principle on the weeds to be controlled, thus broadening the range of action of the two active ingredients in particular in the following two aspects: firstly, reducing the activity of the individual compounds dosage, while maintaining a good level of action; secondly, the composition of the present invention can also achieve a high level of weed control in the case of individual substances becoming ineffective from an agricultural point of view in the low dosage range. The result is a significant broadening of the weed spectrum and additionally increased selectivity for beneficial plant crops, which is exactly what is needed and desired in the event of unintentional overuse of active ingredients. The composition of the present invention has greater adaptability to subsequent crops while maintaining good control of weeds in beneficial plants.
本发明还提供一种增效除草组合物，包含所述有效量的活性化合物组合与至少一种制剂技术常用助剂混合。 The present invention also provides a synergistic herbicidal composition comprising said effective amount of active compound combination mixed with at least one adjuvant commonly used in formulation technology.
本发明的增效除草组合物中使用的助剂包括液体载体、固体载体、分散剂、乳化剂、稳定剂、防冻剂、增稠剂等及其它有益于有效成分在制剂中稳定和药效发挥的已知物质，都是农药中常用或允许使用的各种成分，并无特别限定，具体成分和用量根据配方要求通过简单试验确定。 The auxiliaries used in the synergistic herbicidal composition of the present invention include liquid carriers, solid carriers, dispersants, emulsifiers, stabilizers, antifreeze agents, thickeners, etc. The known substances are the various ingredients commonly used or allowed to be used in pesticides, and there are no special restrictions. The specific ingredients and dosage are determined through simple tests according to the formula requirements.
适合制备本发明的增效除草组合物的液体载体包括芳烃、脂肪烃。特别适用的是极性溶剂，如醇类以及它们的醚和酯。此外还有植物油和甲基溶纤维。同时，不同液体的混合物也是适用的。 Liquid carriers suitable for preparing the synergistic herbicidal composition of the present invention include aromatic hydrocarbons and aliphatic hydrocarbons. Particularly suitable are polar solvents such as alcohols and their ethers and esters. There are also vegetable oils and methyl lysol. Also, mixtures of different liquids are suitable.
适合本发明的增效除草组合物的固体载体是硅藻土、硅酸铝镁、活性白土、高岭土、粘土、石膏、膨润土、白炭黑、轻质碳酸钙、石灰石、木屑、玉米淀粉、可溶性淀粉等。 The solid carrier suitable for the synergistic herbicidal composition of the present invention is diatomaceous earth, magnesium aluminum silicate, attapulgite, kaolin, clay, gypsum, bentonite, white carbon black, light calcium carbonate, limestone, wood chips, corn starch, soluble Starch etc.
适合制备本发明的增效除草组合物的乳化剂可为阴离子和/或非例子型乳化剂，例如烷基酚聚氧乙烯醚、烷基酚聚氧乙烯聚氧丙烯醚、苄基酚聚氧乙烯醚、聚氧乙烯脂肪酸酯、聚氧乙烯脂肪醇醚、聚氧乙烯脂肪胺、烷基酚聚乙二醇醚等。 Emulsifiers suitable for the preparation of the synergistic herbicidal compositions of the present invention may be anionic and/or non-exemplary emulsifiers, such as alkylphenol polyoxyethylene ethers, alkylphenol polyoxyethylene polyoxypropylene ethers, benzylphenol polyoxyethylene Vinyl ether, polyoxyethylene fatty acid ester, polyoxyethylene fatty alcohol ether, polyoxyethylene fatty amine, alkylphenol polyethylene glycol ether, etc.
适合制备本发明的增效除草组合物的分散剂可以为烷基萘磺酸盐、双（烷基）萘磺酸盐甲醛缩合物、萘磺酸甲醛缩合物、烷基酚聚氧乙烯基磷酸盐、烷基酚聚氧乙烯基醚甲醛缩合物硫酸盐、烷基酚聚氧乙烯醚磷酸酯、烷基酚聚氧乙烯醚、蓖麻油环氧乙烷加成物、环氧乙烷-环氧丙烷嵌段共聚物、烷基酚聚氧乙烯醚甲醛缩合污、辛基酚聚氧乙烯基醚硫酸盐和甲基纤维素。例如木质素磺酸钠、木质素磺酸钙、甲基萘磺酸钠甲醛缩合物、萘磺酸钠甲醛缩合污、亚甲基萘磺酸钠等。 The dispersant suitable for preparing the synergistic herbicidal composition of the present invention can be alkylnaphthalenesulfonate, bis(alkyl)naphthalenesulfonate formaldehyde condensate, naphthalenesulfonic acid formaldehyde condensate, alkylphenol polyoxyethylene phosphoric acid Salt, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, alkylphenol polyoxyethylene ether, castor oil ethylene oxide adduct, ethylene oxide-cyclo Propylene oxide block copolymer, alkylphenol ethoxylate formaldehyde condensation, octylphenol ethoxylate sulfate and methylcellulose. For example, sodium lignosulfonate, calcium lignosulfonate, sodium methylnaphthalenesulfonate formaldehyde condensate, sodium naphthalenesulfonate formaldehyde condensation, sodium methylenenaphthalenesulfonate, etc.
其它添加剂，可以举出在制剂时通常以助剂形式使用的羧甲基纤维素，乙二醇和丙二醇等。 Other additives include carboxymethyl cellulose, ethylene glycol and propylene glycol, which are usually used as auxiliary agents in formulations.
本发明中的协同除草组合物还可以含有着色剂，例如无机颜料氧化铁、氧化钛或普鲁士兰；有机染料阿利札林、偶氮染料、金属酞菁兰或三苯甲烷染料等。 The synergistic herbicidal composition of the present invention may also contain coloring agents, such as inorganic pigments iron oxide, titanium oxide or Prussian blue; organic dyes Alizarin, azo dyes, metal phthalocyanine blue or triphenylmethane dyes and the like.
可以任何常用的形式使用本发明的组合物。 The compositions of the present invention may be used in any conventional form.
GR:颗粒剂 GR: Granules
WP:可湿性粉剂 WP: wettable powder
WG:水可分散粒剂 WG: water dispersible granules
SG:可溶粒剂 SG: Soluble Granules
SL:可溶液剂 SL: soluble solution
EC:乳油 EC: EC
EW:水乳剂 EW: emulsion in water
ME:微乳剂 ME: microemulsion
SC:悬浮剂 SC: suspending agent
CS:微囊悬浮剂 CS: microcapsule suspension
OD:油基悬浮剂 OD: oil-based suspending agent
SE:悬乳剂 SE: Suspoemulsion
本发明优选的剂型可以是可湿性粉剂、乳油、悬浮剂、油悬浮剂、微囊剂、微乳剂、水乳剂、悬浮乳剂、水分散粒剂、ZC、超低容量液剂。 The preferred dosage form of the present invention can be wettable powder, emulsifiable concentrate, suspension concentrate, oil suspension concentrate, microcapsule, microemulsion, water emulsion, suspoemulsion, water dispersible granule, ZC, ultra-low volume liquid.
对于水分散粒剂来说，本领域技术人员很熟悉使用相应的助剂完成本发明。分散剂选自聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐、烷基酚聚氧乙烯醚、EO/PO嵌段聚醚；润湿剂选自烷基硫酸盐、烷基磺酸盐、萘磺酸盐、木质素磺酸钠、脂肪醇聚氧乙烯醚、烷基酚聚氧乙烯醚；崩解剂选自硫酸铵、硫酸钠、氯化钠、氯化铵、尿素、蔗糖、葡萄糖、羧甲基纤维素、可溶淀粉、聚乙烯吡咯烷酮；粘结剂选自聚乙烯醇、可溶性淀粉、糊精、黄原胶、羧甲基(乙基)纤维素类；填料选自硅藻土、高岭土、白炭黑、轻质碳酸钙、滑石粉、凹凸棒土、陶土。 For water-dispersible granules, those skilled in the art are familiar with the use of corresponding adjuvants to complete the present invention. The dispersant is selected from polycarboxylate, lignosulfonate, alkylnaphthalene sulfonate, alkylphenol polyoxyethylene ether, EO/PO block polyether; the wetting agent is selected from alkyl sulfate, alkyl Sulfonate, naphthalene sulfonate, sodium lignosulfonate, fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether; disintegrant selected from ammonium sulfate, sodium sulfate, sodium chloride, ammonium chloride, urea , sucrose, glucose, carboxymethyl cellulose, soluble starch, polyvinylpyrrolidone; binder is selected from polyvinyl alcohol, soluble starch, dextrin, xanthan gum, carboxymethyl (ethyl) cellulose; filler It is selected from diatomite, kaolin, white carbon black, light calcium carbonate, talcum powder, attapulgite, clay.
对可湿性粉剂，可使用的助剂有：分散剂选自聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐；润湿剂选自烷基硫酸盐、烷基磺酸盐、萘磺酸盐；填料选自硫酸铵、尿素、蔗糖、葡萄糖、硅藻土、高岭土、白炭黑、轻质碳酸钙、滑石粉、凹凸棒土、陶土。 For wettable powders, the auxiliary agents that can be used are: dispersant selected from polycarboxylate, lignosulfonate, alkyl naphthalene sulfonate; wetting agent selected from alkyl sulfate, alkyl sulfonate, Naphthalene sulfonate; the filler is selected from ammonium sulfate, urea, sucrose, glucose, diatomaceous earth, kaolin, white carbon black, light calcium carbonate, talcum powder, attapulgite, clay.
对悬浮剂，可使用的助剂有：分散剂选自聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐、TERSPERSE2425(美国亨斯迈公司出品，烷基萘磺酸盐类)；乳化剂选自农乳700#(通用名：烷基酚甲醛树脂聚氧乙烯醚)、农乳2201、斯盘-60#(通用名：山梨醇酐单硬脂酸酯)、乳化剂T-60(通用名：失水山梨醇单硬脂酸酯聚氧乙烯醚)、农乳1601#(通用名：苯乙基苯酚聚氧乙烯聚氧丙烯醚)、TERSPERSE4894(美国亨斯迈公司出品)；润湿剂选自烷基酚聚氧乙烯基醚甲醛缩合物硫酸盐、烷基酚聚氧乙烯基醚磷酸酯、苯乙基酚聚氧乙烯基醚磷酸酯、烷基硫酸盐、烷基磺酸盐、萘磺酸盐、TERSPERSE2500(美国亨斯迈公司出品)；增稠剂选自黄原胶、聚乙烯醇、膨润土、硅酸镁铝；防腐剂选自甲醛、苯甲酸、苯甲酸钠；消泡剂为有机硅类消泡剂；防冻剂选自乙二醇、丙二醇、甘油、尿素、无机盐类(如氯化钠)。 For the suspending agent, the auxiliary agents that can be used are: the dispersant is selected from polycarboxylates, lignin sulfonates, alkylnaphthalene sulfonates, TERSPERSE2425 (produced by Huntsman Corporation of the United States, alkylnaphthalene sulfonates) The emulsifier is selected from Nongru 700# (common name: alkylphenol formaldehyde resin polyoxyethylene ether), Nongru 2201, Span-60# (common name: sorbitan monostearate), emulsifier T -60 (common name: sorbitan monostearate polyoxyethylene ether), Nongru 1601# (common name: phenylethylphenol polyoxyethylene polyoxypropylene ether), TERSPERSE4894 (produced by Huntsman, USA ); the wetting agent is selected from alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, phenethylphenol polyoxyethylene ether phosphate, alkyl sulfate, alkane Base sulfonate, naphthalene sulfonate, TERSPERSE2500 (produced by Huntsman, USA); thickener is selected from xanthan gum, polyvinyl alcohol, bentonite, magnesium aluminum silicate; preservative is selected from formaldehyde, benzoic acid, benzene Sodium formate; defoamer is organosilicon defoamer; antifreeze is selected from ethylene glycol, propylene glycol, glycerin, urea, inorganic salts (such as sodium chloride).
对可分散油悬浮剂，可使用的助剂有：分散剂选自聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐(扩散剂NNO)、TERSPERSE2425，乳化剂选自BY(蓖麻油聚氧乙烯醚)系列乳化剂(BY-110、BY-125、BY-140)农乳700#(通用名：烷基酚甲醛树脂聚氧乙烯醚)、农乳2201、斯盘-60#(通用名：山梨醇酐单硬脂酸酯)、吐温-60#(通用名：失水山梨醇单硬脂酸酯聚氧乙烯醚)、农乳1601#(通用名：苯乙基苯酚聚氧乙烯聚氧丙烯醚)、TERSPERSE4894；润湿剂选自烷基酚聚氧乙烯基醚甲醛缩合物硫酸盐、烷基酚聚氧乙烯醚磷酸酯、苯乙基酚聚氧乙烯基醚磷酸酯、烷基硫酸盐、烷基磺酸盐、萘磺酸盐、TERSPERSE2500；增稠剂选自白炭黑、聚乙烯醇、膨润土、硅酸镁铝；防冻剂选自乙二醇、丙二醇、甘油、尿素、无机盐类(如氯化钠)；稳定剂选自环氧大豆油、环氧氯丙烷、磷酸三苯酯；分散介质选自大豆油、菜籽油、玉米油、油酸甲酯、柴油、机油、矿物油。 For dispersible oil suspensions, the auxiliary agents that can be used are: the dispersant is selected from polycarboxylate, lignosulfonate, alkylnaphthalene sulfonate (diffusion agent NNO), TERSPERSE2425, and the emulsifier is selected from BY (castor Sesame oil polyoxyethylene ether) series emulsifier (BY-110, BY-125, BY-140) Nongru 700# (common name: alkylphenol formaldehyde resin polyoxyethylene ether), Nongru 2201, Span-60# (common name: sorbitan monostearate), Tween-60# (common name: sorbitan monostearate polyoxyethylene ether), Nongru 1601# (common name: phenylethylphenol Polyoxyethylene polyoxypropylene ether), TERSPERSE4894; wetting agent selected from alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, phenethylphenol polyoxyethylene ether phosphoric acid Ester, alkyl sulfate, alkyl sulfonate, naphthalene sulfonate, TERSPERSE2500; thickener selected from white carbon black, polyvinyl alcohol, bentonite, magnesium aluminum silicate; antifreeze selected from ethylene glycol, propylene glycol, glycerin , urea, inorganic salts (such as sodium chloride); stabilizer is selected from epoxy soybean oil, epichlorohydrin, triphenyl phosphate; dispersion medium is selected from soybean oil, rapeseed oil, corn oil, methyl oleate , diesel, engine oil, mineral oil.
适合桶混组合物的剂型实例是溶液、稀释乳剂、悬浮剂或其混合和粉剂。 Examples of dosage forms suitable for tank-mix compositions are solutions, dilute emulsions, suspensions or mixtures thereof and powders.
通常，桶混组合物是用溶剂（如水）稀释而成的含不同农药，和任选地进一步助剂的一种或多种预混组合物。 Typically, tank mix compositions are one or more premix compositions containing different pesticides, and optionally further adjuvants, diluted with a solvent such as water.
一般，叶面桶混剂包含0.1-20%，特别是0.1-15%的活性化合物，和99.9%-80%，特别是99.9-85%的固态或液态助剂（包含溶剂比如水），其中助剂可以是以桶混剂为基础，含量0-20%，特别是0.1-15%的表面活性剂。 In general, foliar tankmixes contain 0.1-20%, especially 0.1-15%, of active compound, and 99.9%-80%, especially 99.9-85%, of solid or liquid adjuvants (including solvents such as water), wherein The auxiliaries can be based on tank mixes, with a content of 0-20%, especially 0.1-15% surfactants.
通常叶面施用的预混剂包含0.1-99.9%，特别是1-95%的活性成分化合物，和99.9-0.1%，特别是99-5%的固态或者液态助剂（包含如溶剂比如水），其中助剂可以是以预混剂为基础，含量0-50%，特别是0.5-40%的表面活性剂。 Usually a premix for foliar application contains 0.1-99.9%, especially 1-95% of active ingredient compound, and 99.9-0.1%, especially 99-5% of solid or liquid adjuvant (including e.g. solvent such as water) , wherein the auxiliary agent can be based on the premix, with a content of 0-50%, especially a surfactant of 0.5-40%.
本发明的经配制的组合物包含0.5-99.9%，特别是1-95%，有利地是1-50%的活性成分化合物，和99.5-0.1%，特别是99-5%质量的固体或液体辅剂（包含如溶剂如水），其中所述助剂（或辅剂）可以是基于预混剂质量的0-50%，特别是0.5-40%的表面活性剂。 The formulated composition according to the invention comprises 0.5-99.9%, especially 1-95%, advantageously 1-50% of active ingredient compound, and 99.5-0.1%, especially 99-5% by mass of solid or liquid Adjuvant (including solvent such as water), wherein the adjuvant (or adjuvant) can be 0-50% based on the mass of the premix, especially 0.5-40% surfactant.
根据制剂特性，可以按照预期对象和流行环境来选自施用方法，如叶面、浸透、喷雾、喷粉、散射进行选择。 According to the characteristics of the preparation, the application method can be selected according to the intended object and the prevailing environment, such as foliage, soaking, spraying, dusting, and scattering.
应用时，制剂可以是商品形式，如需要，以常规方式稀释，例如用水稀释可湿性粉剂、乳油、分散剂和水分散粒剂。对于粉剂，土壤施用颗粒剂，撒播粒剂和喷雾溶液类型的制剂，一般在使用前不再用其它惰性物质稀释。 When used, the preparations can be in commercial form and, if necessary, diluted in a conventional manner, such as diluting wettable powders, emulsifiable concentrates, dispersions and water-dispersible granules with water. For dusts, soil application granules, broadcast granules and spray solution type formulations, they are generally not diluted with other inert substances before use.
可将活性物质施用至植物、植物各组织，植物种子或栽培区域（耕过的），优选施用至绿色植物和植物各组织以及，如需要，还包括耕过的土壤中。 The active substances can be applied to plants, plant tissues, plant seeds or cultivated areas (cultivated), preferably to green plants and plant tissues and, if desired, also to cultivated soil.
活性成分的可能使用形式包括以罐混形式混合施用，其中每种物质是以最佳剂型存在的浓缩制剂，在罐中将它们与水混合，并施用由此获得的喷雾混合物。 Possible forms of use of the active ingredients include mixed application in tank mix form, where each substance is a concentrated formulation in the optimal dosage form, mixing them with water in a tank, and applying the spray mixture thus obtained.
本发明由活性物质(A)和(B)混合的除草组合物的优点是更方便施用，因为各组分用量已经调整到适当比例。而且，这种方式可以最佳方式互相选择适合的助剂，而将各种制剂进行灌混可能导致混合有不需要的助剂。 The advantage of the herbicidal composition of the present invention which is a mixture of active substances (A) and (B) is that it is more convenient to apply, because the dosage of each component has been adjusted to an appropriate ratio. Furthermore, in this way suitable adjuvants can be optimally selected from one another, whereas pouring various formulations may result in the admixture of undesired adjuvants.
本发明还提供一种防治不希望有的植物的方法，包括将所述的增效除草组合物在苗前、苗后、或苗前和苗后施用至植物、植物各组织、植物种子上或栽培区域。所述不希望有的植物为单子叶杂草、双子叶杂草。不希望有的植物如繁缕属、豆瓣菜属、剪股颖属、马唐属、燕麦属、狗尾草属、欧白芥属、黑麦草属、茄属、雀麦属、看麦娘属、母菊属、茼麻属、黄花稔属、苍耳属、苋属、藜属、番薯属、茼蒿属、猪殃殃属、堇菜属和婆婆纳属。 The present invention also provides a method for controlling unwanted plants, comprising applying said synergistic herbicidal composition to plants, plant tissues, plant seeds or cultivation area. Said undesired plants are monocotyledonous weeds, dicotyledonous weeds. Undesirable plants such as chickweed, watercress, bentgrass, crabgrass, oats, foxtail, white mustard, ryegrass, nightshade, brome, aleuria, Matricaria, Chrysanthemum, Chrysanthemum, Cocklebur, Amaranthus, Chenopodium, Ipomoea batatas, Chrysanthemum chrysanthemum, Sorrelia, Viola, and Possum.
栽培区是栽培植物已在生长或那些栽培植物的种子已播种的土地，以及打算栽培上述栽培植物的土地。 The cultivation area is the land where cultivated plants have been growing or the seeds of those cultivated plants have been sown, and the land where the above-mentioned cultivated plants are intended to be cultivated.
适用于本发明的组合物的组合的协同有效量可以根据当时的条件如杂草压力、施用时间、施用方式、天气、土壤状况、地形特征、目标作物的种类等变化。在实施应用中，足够提供约0.001kg/ha-1.00kg/ha,优选约0.01kg/ha-0.075kg/ha的活性组分的施用率是合适的。 The synergistically effective amount of the combination of compositions suitable for the present invention may vary according to prevailing conditions such as weed pressure, application time, application method, weather, soil conditions, topographic features, target crop species, and the like. In practical applications, application rates sufficient to provide about 0.001 kg/ha to 1.00 kg/ha, preferably about 0.01 kg/ha to 0.075 kg/ha of active ingredient are suitable.
本发明方法最优选用于防治作物生长区或将用于种植作物的区域内的杂草。当用于作物生长区时，施用量应足以控制杂草生长但又不会对作物产生严重的永久性的伤害。 The method of the present invention is most preferably used for controlling weeds in areas where crops are grown or in areas where crops are to be grown. When used in crop growing areas, the rate of application should be sufficient to control weed growth without causing serious and permanent crop damage.
本发明的除草组合物可以在苗前施用也可以在苗后施用，也可以在苗前和苗后施用。优选苗后施用，特别是杂草生长早期。用除草组合物在种植前早期处理（特别是土壤表面施用）也是本发明方法的特征之一。 The herbicidal composition of the present invention can be applied either pre-emergence or post-emergence, or both pre-emergence and post-emergence. Post-emergence application is preferred, especially early weed growth. Early treatment (especially soil surface application) with the herbicidal composition before planting is also one of the features of the method according to the invention.
本发明的除草组合物在出苗前施用于土壤表面，它或者完全阻止杂草出苗，或当杂草苗长至真叶期时停止生长，继之在3至4周后完全死亡。 The herbicidal composition of the present invention, applied to the soil surface before emergence, either completely prevents the emergence of weeds, or stops growth when the weeds reach the true leaf stage, followed by complete death after 3 to 4 weeks.
在出苗后将除草组合物施用于植株的绿色部分，在给药处理后很快停止生长。杂草的植株停留在用药处理的生长阶段或经过一段时间后迅速死亡，用这种方式可以使那些对于农作物具有竞争作用的杂草通过使用本发明的组合物尽早或永久地被除去。因此这种方式可以迅速而持久地减少对作物有害的杂草竞争。 The herbicidal composition is applied to the green parts of the plants after emergence, and growth ceases shortly after the application of the treatment. The plants of the weeds remain in the growth stage of the treatment or die quickly after a period of time, in this way those weeds which compete with the crops can be eliminated early or permanently by using the composition of the invention. In this way, weed competition, which is harmful to crops, can be quickly and permanently reduced.
与单剂相比，本发明的增效除草组合物具有更迅速和更持久的除草作用。特别有利的是可以将组合物中（A）和（B）的有效剂量调整至一种低水平，以使得它们的土壤作用达到最佳。因此，首先不仅可以应用于敏感作物，而且基本上避免了地下水污染。通过使用本发明的增效除草组合物，可以显著降低活性物质的施用量。 The synergistic herbicidal composition of the present invention has a faster and longer-lasting herbicidal action than a single agent. It is especially advantageous that the effective dosage of (A) and (B) in the composition can be adjusted to a low level to optimize their soil action. Therefore, first of all, it can not only be applied to sensitive crops, but also basically avoid groundwater pollution. By using the synergistic herbicidal compositions according to the invention, the application rates of active substances can be significantly reduced.
本发明的除草组合物对于单子叶和双子叶杂草具有优良的除草活性，对抗性油菜、抗性大豆的危害非常小或完全没有危害。 The herbicidal composition of the present invention has excellent herbicidal activity on monocot and dicotyledon weeds, and does little or no harm to resistant rapeseed and resistant soybean.
抗性油菜，抗性大豆包括： Resistant canola, resistant soybeans include:
以改进植物中的淀粉合成为目的的作物基因重组改性；（例如WO92/11376，WO92/14827，WO91/19806）; Gene recombination modification of crops for the purpose of improving starch synthesis in plants; (eg WO92/11376, WO92/14827, WO91/19806);
抗其他除草剂例如抗磺酰脲类除草剂的转基因作物（EP-A0257993，US-A5013659）; Transgenic crops resistant to other herbicides such as sulfonylurea herbicides (EP-A0257993, US-A5013659);
抗其他除草剂例如抗磺酰脲除草剂的非转基因作物（CN102405846）; Non-transgenic crops resistant to other herbicides such as sulfonylurea herbicides (CN102405846);
可产生芽孢杆菌苏云金菌霉素（Bt毒素）的转基因作物，即可以使该植物产生对某些害虫的抗性（EP-A0142924，EP-A-0193259）; Transgenic crops producing Bacillus thuringiensis (Bt toxin), i.e. rendering the plant resistant to certain pests (EP-A0142924, EP-A-0193259);
具有改进脂肪酸组成的转基因作物（WO91/13972）. Transgenic crops with improved fatty acid composition (WO91/13972).
原则上抗性植物可以是任意种类的所需植物，即，可以是单子叶和双子叶植物。 The resistant plants can in principle be any desired plant species, ie both monocotyledonous and dicotyledonous plants.
因此本发明还涉及一种控制抗性油菜、抗性大豆作物中不需要的植物生长的方法，其中包括将化合物（A）中的至少一种和化合物(B)中的至少一种施用至有害植物，其各组织或栽培区域。 The present invention therefore also relates to a method of controlling unwanted vegetation in resistant rapeseed, resistant soybean crops, which comprises applying at least one of compounds (A) and at least one of compounds (B) to harmful Plants, their individual tissues or areas of cultivation.
本发明还涉及化合物（A）+(B)的除草组合物，以及包含它们的除草剂组合物。 The present invention also relates to herbicidal compositions of compounds (A)+(B), and herbicidal compositions comprising them.
制剂实施例 Formulation example
实施例1：油悬浮剂 Embodiment 1: oil suspension
化合物A25% Compound A25%
化合物B1% Compound B1%
甲基萘磺酸钠甲醛缩合物10% Sodium methyl naphthalene sulfonate formaldehyde condensate 10%
膨润土1% Bentonite 1%
丙三醇5% Glycerol 5%
玉米油补足至100% Corn oil supplemented to 100%
将活性组分、分散剂、润湿剂和玉米油等各组分按照配方的比例混合均匀，经研磨和/或高速剪切后得到油悬浮剂。 The active component, dispersant, wetting agent, corn oil and other components are uniformly mixed according to the ratio of the formula, and the oil suspension is obtained after grinding and/or high-speed shearing.
实施例2可湿性粉剂 Embodiment 2 wettable powder
化合物A10% Compound A10%
化合物B2% Compound B2%
十二烷基硫酸钠10% Sodium Lauryl Sulfate 10%
木质素磺酸钠5% Sodium lignosulfonate 5%
白炭黑10% Silica 10%
高岭土补足至100% Kaolin supplemented to 100%
将活性成分、各种助剂及填料等按配方的比例成分混合，经超细粉碎机粉碎后，即得到可湿性粉剂。 The active ingredient, various additives and fillers are mixed according to the proportion of the formula, and after being pulverized by an ultrafine pulverizer, a wettable powder can be obtained.
实施例3可湿性粉剂 Embodiment 3 wettable powder
化合物A1% Compound A1%
化合物B50% Compound B50%
十二烷基苯磺酸钙1% Calcium dodecylbenzenesulfonate 1%
木质素磺酸钠2% Sodium lignosulfonate 2%
白炭黑补足至100% Silica topped up to 100%
将活性成分、各种助剂及填料等按配方的比例成分混合，经超细粉碎机粉碎后，即得到可湿性粉剂。 The active ingredient, various additives and fillers are mixed according to the proportion of the formula, and after being pulverized by an ultrafine pulverizer, a wettable powder can be obtained.
实施例4水分散粒剂 Embodiment 4 water dispersible granules
化合物A0.1% Compound A0.1%
化合物B1% Compound B1%
木质素磺酸钠4% Sodium lignosulfonate 4%
十二烷基硫酸钠5% Sodium Lauryl Sulfate 5%
尿素5% Urea 5%
高岭土补足至100% Kaolin supplemented to 100%
将活性成分、分散剂、润湿剂、崩解剂和填料按配方的比例混合均匀，经过气流粉碎成可湿性粉剂，再加入一定量的水混合挤压造料。经干燥筛分后得到水分散粒剂。 The active ingredient, dispersant, wetting agent, disintegrant and filler are uniformly mixed according to the ratio of the formula, crushed into a wettable powder by airflow, and then a certain amount of water is added to mix and extrude the material. After drying and sieving, water-dispersible granules were obtained.
实施例5乳油 Embodiment 5 emulsifiable concentrate
化合物A5% Compound A5%
化合物B0.1% Compound B0.1%
乙氧基化蓖麻油5% Ethoxylated Castor Oil 5%
十二烷基苯磺酸钙3% Calcium dodecylbenzenesulfonate 3%
二甲基亚砜补足至100% Dimethyl sulfoxide supplemented to 100%
将上述成分按照比例配制，搅拌均匀得到均一的相。 Prepare the above-mentioned ingredients according to the proportion, and stir evenly to obtain a homogeneous phase.
实施例6油悬乳剂 Embodiment 6 oil suspoemulsion
化合物A10% Compound A10%
化合物B0.1% Compound B0.1%
甲基萘磺酸钠甲醛缩合物5% Sodium methyl naphthalene sulfonate formaldehyde condensate 5%
乙氧基化蓖麻油3% Ethoxylated Castor Oil 3%
膨润土1% Bentonite 1%
芳烃溶剂10020% Aromatic solvent 10020%
水补足至100% Make up to 100% with water
将化合物B、甲基萘磺酸钠甲醛缩合物经研磨和/或高速剪切后得到化合物B悬浮剂；将化合物A、芳烃溶剂100、乙氧基化蓖麻油混合搅拌均匀得到化合物A的乳油；将得到的化合物B加入到化合物A油悬浮剂中，得到悬乳剂。 Grinding and/or high-speed shearing compound B and sodium methylnaphthalenesulfonate formaldehyde condensate to obtain compound B suspending agent; mixing and stirring compound A, aromatic hydrocarbon solvent 100, and ethoxylated castor oil to obtain compound A emulsifiable oil ; The obtained compound B is added to the compound A oil suspension to obtain a suspoemulsion.
实施例7可湿性粉剂 Embodiment 7 wettable powder
化合物A20% Compound A20%
化合物B1% Compound B1%
十二烷基硫酸钠10% Sodium Lauryl Sulfate 10%
木质素磺酸钠5% Sodium lignosulfonate 5%
白炭黑10% Silica 10%
高岭土补足至100% Kaolin supplemented to 100%
将上述组分按比例混合，并研磨、粉碎，制备成可湿性粉剂。 The above components are mixed in proportion, ground and pulverized to prepare wettable powder.
实施例8水分散粒剂 Embodiment 8 water dispersible granules
化合物A40% Compound A40%
化合物B4% Compound B4%
改性木质素磺酸钙5% Modified Calcium Lignosulfonate 5%
十二烷基硫酸钠5% Sodium Lauryl Sulfate 5%
尿素5% Urea 5%
高岭土补足至100% Kaolin supplemented to 100%
将化合物A活性成分、分散剂、润湿剂、崩解剂和填料按配方的比例混合均匀，经过气流粉碎成可湿性粉剂；再加入化合物B混合均匀；再加入一定量的水混合挤压造料。经干燥筛分后得到水分散粒剂。 Mix the active ingredient of compound A, dispersant, wetting agent, disintegrant and filler uniformly according to the ratio of the formula, and then crush it into a wettable powder through airflow; then add compound B and mix uniformly; then add a certain amount of water and mix and extrude to make material. After drying and sieving, water-dispersible granules were obtained.
实施例9悬乳剂 Embodiment 9 suspoemulsion
油相： Oil phase:
化合物A2% Compound A2%
油酸甲酯10% Methyl Oleate 10%
乙氧基化蓖麻油5% Ethoxylated Castor Oil 5%
水相： water box:
化合物B50% Compound B50%
改性木质素磺酸钙1% Modified Calcium Lignosulfonate 1%
水补足至100% Make up to 100% with water
将化合物A溶解在油酸甲酯中，加入乙氧基化蓖麻油得到油相；按照配方将化合物B、改性木质素磺酸钙和水，砂磨得到化合物B的悬浮水相；在搅拌下将油相加入水相得到悬乳剂。 Compound A was dissolved in methyl oleate, and ethoxylated castor oil was added to obtain an oil phase; Compound B, modified calcium lignosulfonate and water were sand-milled to obtain a suspended aqueous phase of Compound B according to the formula; The oil phase is added to the water phase to obtain a suspoemulsion.
实施例10可湿性粉剂 Embodiment 10 wettable powder
化合物A5% Compound A5%
化合物B10% Compound B10%
木质素磺酸钠1% Sodium lignosulfonate 1%
月桂基硫酸钠2% Sodium Lauryl Sulfate 2%
高度分散的硅酸1% Highly dispersed silicic acid 1%
高岭土补足至100% Kaolin supplemented to 100%
将上述组分按比例混合，并研磨、粉碎，制备成可湿性粉剂。 The above components are mixed in proportion, ground and pulverized to prepare wettable powder.
实施例11包衣颗粒剂 Example 11 Coated Granules
化合物A1% Compound A1%
化合物B25% Compound B25%
聚乙二醇3% Polyethylene glycol 3%
高度分散的硅酸1% Highly dispersed silicic acid 1%
碳酸钙补足至100% Calcium carbonate supplemented to 100%
在混合器中，将磨细的活性成分均匀涂布到被聚乙二醇润湿的载体上。以此方式可获得无尘包衣颗粒剂。 In a mixer, the finely divided active ingredient is spread homogeneously onto a carrier moistened with polyethylene glycol. Dust-free coated granules can be obtained in this way.
实施例12可湿性粉剂 Embodiment 12 wettable powder
化合物A1% Compound A1%
化合物B5% Compound B5%
十二烷基硫酸钠1% Sodium Lauryl Sulfate 1%
木质素磺酸钠1% Sodium lignosulfonate 1%
高岭土补足至100% Kaolin supplemented to 100%
将上述组分按比例混合，并研磨、粉碎，制备成可湿性粉剂。 The above components are mixed in proportion, ground and pulverized to prepare wettable powder.
实施例13挤出颗粒剂 Example 13 extruded granules
化合物A20% Compound A20%
化合物B10% Compound B10%
木质素磺酸钠4% Sodium lignosulfonate 4%
羧甲基纤维素2% Carboxymethylcellulose 2%
高岭土补足至100% Kaolin supplemented to 100%
将活性组分与助剂混合并研磨，混合物用水润湿。将该混合物挤出，然后在空气流中干燥。 The active ingredient is mixed with the auxiliaries and ground, and the mixture is moistened with water. The mixture is extruded and dried in a stream of air.
实施例14ZC Example 14ZC
Atlox49134% Atlox49134%
柠檬酸0.05% Citric acid 0.05%
催化剂0.1% Catalyst 0.1%
水13% Water 13%
化合物B10% Compound B10%
PAPI1.35% PAPI1.35%
Solvesso20010% Solvesso20010%
Atlox491316% Atlox491316%
分散剂LFH0.3% Dispersant LFH0.3%
消泡剂0.16% Defoamer 0.16%
尿素8.4% Urea 8.4%
化合物A0.1% Compound A0.1%
水补足至100% Make up to 100% with water
将PAPI、化合物A、Solvesso100形成的油相加入含Atlox4913的水溶液中，形成乳状液。然后加热并保温在50oC下加入催化剂反应2小时。冷却后得到化合物A的微囊剂。 The oil phase formed by PAPI, compound A and Solvesso100 was added to the aqueous solution containing Atlox4913 to form an emulsion. Then heat and keep warm at 50oC and add the catalyst to react for 2 hours. Microcapsules of Compound A were obtained after cooling.
Atlox4913,分散剂LFH,消泡剂，尿素，化合物B和水按比例混合均匀，并经砂磨，制备成悬浮剂。 Atlox4913, dispersant LFH, defoamer, urea, compound B and water are mixed uniformly in proportion, and sand milled to prepare a suspension.
将得到的化合物A微囊剂加入化合物B的悬浮剂中，搅拌均匀得到ZC。 Add the obtained compound A microcapsules into the compound B suspension, and stir evenly to obtain ZC.
实施例16悬浮乳剂 Embodiment 16 suspoemulsion
化合物A10% Compound A10%
化合物B12% Compound B12%
Solvesso20010% Solvesso20010%
乙氧基化蓖麻油4% Ethoxylated Castor Oil 4%
脂肪醇聚氧乙烯醚磺基琥珀酸单酯二钠5% Fatty alcohol polyoxyethylene ether monosodium sulfosuccinate 5%
改性木质素磺酸钙5% Modified Calcium Lignosulfonate 5%
黄原胶1% Xanthan Gum 1%
膨润土1% Bentonite 1%
丙三醇5% Glycerol 5%
水补足至100% Make up to 100% with water
将化合物A溶解在Solvesso200中，加入乙氧基化蓖麻油，得到化合物A的乳油； Compound A is dissolved in Solvesso200, and ethoxylated castor oil is added to obtain the emulsifiable oil of compound A;
将化合物B、脂肪醇聚氧乙烯醚磺基琥珀酸单酯二钠，上述各组分按比例混合均匀，并经砂磨，制备成悬浮剂。 Compound B, disodium fatty alcohol polyoxyethylene ether sulfosuccinate monoester, and the above-mentioned components are uniformly mixed in proportion, and sand-milled to prepare a suspending agent.
将含化合物A的油相加入到含化合物B的悬浮剂中，得到悬浮乳剂。 The oil phase containing compound A is added to the suspension containing compound B to obtain a suspoemulsion.
实施例17乳油 Embodiment 17 emulsifiable concentrate
化合物A10% Compound A10%
化合物B2% Compound B2%
乙氧基化蓖麻油5% Ethoxylated Castor Oil 5%
十二烷基苯磺酸钙3% Calcium dodecylbenzenesulfonate 3%
Solvesso100补足至100% Solvesso100 top up to 100%
将上述各组分混合，搅拌至得到透明均一相。 The above components were mixed and stirred until a clear homogeneous phase was obtained.
实施例1850%化合物A+50%化合物B Embodiment 1850% compound A+50% compound B
化合物A50% Compound A50%
化合物B50% Compound B50%
将化合物A、化合物B按照比例混合均匀。 Mix compound A and compound B evenly in proportion.
生物测试例 biological test case
当活性化合物组合物的作用超过当各活性化合物单独施用时的作用的总和时，存在协同增效作用。两种活性化合物的特定组合的预期作用可使用所谓的"Colby公式"(参见S.R.Colby,"CalculatingSynergisticandAntagonisticResponsesofHerbicideCombinations“,Weeds1967,15,20-22)如下计算:如果 A synergistic effect exists when the effect of the active compound combination exceeds the sum of the effects of the individual active compounds when administered individually. The expected effect of a particular combination of two active compounds can be calculated using the so-called "Colby's formula" (see S.R. Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", Weeds 1967, 15, 20-22) as follows: if
X是当使用用量为mg/ha或浓度为mppm的活性化合物A时的活性； X is the activity when using active compound A in mg/ha or mppm concentration;
Y是当使用用量为ng/ha或浓度为nppm的活性化合物B时的活性，表示为占未处理对照的百分率； Y is the activity when active compound B is used in an amount of ng/ha or nppm, expressed as a percentage of the untreated control;
E是当使用用量为m和ng/ha或浓度为m和nppm的活性化合物A和B时的活性， E is the activity when active compounds A and B are used in m and ng/ha or m and nppm concentrations,
那么 So
如果实际观察的活性（O）大于预期活性（E），那么该组合物超加和，即具有增效作用。 If the actually observed activity (O) is greater than the expected activity (E), then the composition is superadditive, ie synergistic.
发明人通过大量的筛选试验，本发明中涉及到的化合物(A)和（B）的不同组合的不同配比进行了大量的试验以及效果性分析，发现在一定的配比范围内，所得到的除草组合物具有增益效果，而不仅仅是两种药剂的简单相加. The inventor has carried out a large number of tests and effect analysis on the different proportions of the different combinations of the compounds (A) and (B) involved in the present invention through a large number of screening tests, and found that within a certain proportion range, the obtained The herbicidal combination has a gain effect, not just a simple addition of two agents.
1.苗前杂草防治 1. Pre-emergence weed control
在装有沙壤土的纸板盆中放入单子叶和双子叶有害植物的种子或根茎，并用土盖好。将制成浓缩水溶液，可湿性粉剂或乳油形式的组合物以各种剂量将其施用至土壤覆盖层表面。处理后，将盆放在温室中并使杂草保持在良好的生长条件下。在试验3-4周后测试植物出苗后，与未处理对照比较，肉眼观察记录植物伤害情况或对出苗的不利影响。如试验结果所示，本发明组合物在苗前施用，对广谱的单子叶和双子叶杂草具有很好的除草活性。 Put the seeds or rhizomes of monocotyledonous and dicotyledonous harmful plants in cardboard pots filled with sandy loam, and cover them with soil. The compositions in the form of concentrated aqueous solutions, wettable powders or emulsifiable concentrates are applied to the surface of the soil cover in various dosages. After treatment, the pots were placed in a greenhouse and the weeds were kept in good growing conditions. After the test plants emerged 3-4 weeks after the test, compared with the untreated control, the damage to the plants or the adverse effects on the emergence were recorded by visual observation. As shown by the test results, the composition of the present invention has good herbicidal activity on broad-spectrum monocotyledon and dicotyledonous weeds when applied before emergence.
2.苗后除草作用 2. Post-emergence herbicide
在装有沙壤土的纸板盆中放入单子叶和双子叶有害植物的种子或根茎，用土盖好并在良好生长条件的温室中培育。播种3周后，在三叶期用本发明组合物处理测试植物。保持测试植物在最佳生长条件下的温室中约3-4周后，与未处理对照相比，肉眼记录制剂的活性。苗后施用时，本发明组合物也对广谱的经济重要的禾本科和阔叶科杂草具有很好的除草活性。 The seeds or rhizomes of monocotyledonous and dicotyledonous harmful plants are placed in cardboard pots filled with sandy loam, covered with soil and cultivated in a greenhouse under good growing conditions. Three weeks after sowing, the test plants are treated at the three-leaf stage with the composition according to the invention. After keeping the test plants in the greenhouse under optimal growth conditions for approximately 3-4 weeks, the activity of the formulations is recorded visually compared to the untreated control. When applied post-emergence, the compositions according to the invention also have very good herbicidal activity against a broad spectrum of economically important grass and broadleaf weeds.
可以频繁的观察到本发明组合物活性超出除草剂单独使用时的活性总和。观察的试验结果表明，在适当的低剂量下，组合物的活性超过了根据Colby公式计算的预期值。 It is frequently observed that the activity of the compositions of the present invention exceeds the sum of the activities of the herbicides alone. The observed test results show that, at moderately low doses, the activity of the composition exceeds the expected value calculated from the Colby formula.
3.除草活性和作物的耐受性（田间试验） 3. Herbicidal activity and crop tolerance (field trials)
抗磺酰脲除草剂的非转基因油菜作物与典型杂草一起种植在室外自然条件下。另一方面，当油菜植物生长时杂草种群自然发生。苗后2-4叶期对杂草处理。为了体现增效效果，以低于实际施用剂量进行处理。 Non-GM canola crops resistant to sulfonylurea herbicides were grown outdoors under natural conditions with typical weeds. Weed populations, on the other hand, occur naturally when canola plants are growing. Treat weeds at the 2-4 leaf stage after seedlings. In order to reflect the synergistic effect, the treatment was carried out at a dose lower than that actually administered.
表1处理四周后对曼陀罗的除草活性 Table 1 handles herbicidal activity to datura after four weeks
表2处理四周后对狗尾草的除草活性 Table 2 handles herbicidal activity to Setaria after four weeks
表3处理四周后对猪殃殃的除草活性 Table 3 handles the herbicidal activity to swine worms after four weeks
表4处理四周后对繁缕的除草活性 Table 4 Herbicidal activity to chickweed after four weeks of treatment
表5处理四周后对看麦娘的除草活性 Table 5 Herbicidal activity to Amilia miltiorrhiza after four weeks of treatment
根据试验结果可以看出，化合物A和化合物B的除草效果明显较单独采用化合物A或者化合物B更佳，具备明显的增益效果，且在低使用量的有效成分下保持较高的除草活性。此外，两种除草成分较于其中任意一种成分单独施用来说，具有更广的杀草谱，且本组合物具备低毒、低残留的特性，显著提升了对作物生长环境中杂草的防治效果。本实验还观察到，抗性油菜作物在用本发明的增效除草组合物处理后没有被伤害或仅有可忽略程度的损害。 According to the test results, it can be seen that the herbicidal effect of compound A and compound B is obviously better than that of compound A or compound B alone, has obvious gain effect, and maintains high herbicidal activity under low usage of active ingredients. In addition, the two herbicidal components have a wider herbicidal spectrum than any one of them applied alone, and the composition has the characteristics of low toxicity and low residue, which significantly improves the protection against weeds in the crop growth environment. Control effect. It was also observed in this experiment that the resistant rapeseed crops were not injured or were only damaged to a negligible degree after treatment with the synergistic herbicidal composition of the present invention.
本发明的组合物及其之类方法已经通过具体实施例进行了描述。本领域技术人员可以借鉴本发明的内容适当改变原料、工艺条件等环节来实现相应的其他目的，其相关改变都没有脱离本发明的内容，所以类似的替换和改动对于本领域技术人员来说是显而易见的，都被视为包括在本发明的范围之内。 The compositions of the invention and methods thereof have been described by way of specific examples. Those skilled in the art can learn from the content of the present invention to appropriately change the raw materials, process conditions and other links to achieve other corresponding purposes, and the relevant changes do not depart from the content of the present invention, so similar replacements and changes are a must for those skilled in the art. Obviously, all are considered to be included within the scope of the present invention.
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| CN201510640303.4A Pending CN105165871A (en) | 2013-07-03 | 2013-07-03 | Synergistic composition for weeding |
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| CN201510640337.3A Active CN105165875B (en) | 2013-07-03 | 2013-07-03 | Synergistic herbicide compositions |
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| CN201510594682.8A Expired - Fee Related CN105165866B (en) | 2013-07-03 | 2013-07-03 | Synergistic herbicide compositions |
| CN201510640303.4A Pending CN105165871A (en) | 2013-07-03 | 2013-07-03 | Synergistic composition for weeding |
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| CN201510640408.XA Expired - Fee Related CN105165877B (en) | 2013-07-03 | 2013-07-03 | Synergistic herbicide compositions |
| CN201510594681.3A Expired - Fee Related CN105165865B (en) | 2013-07-03 | 2013-07-03 | Synergistic herbicide compositions |
| CN201510640407.5A Expired - Fee Related CN105165876B (en) | 2013-07-03 | 2013-07-03 | Synergistic herbicide compositions |
| CN201510640305.3A Active CN105165873B (en) | 2013-07-03 | 2013-07-03 | Synergistic herbicide compositions |
| CN201510640336.9A Expired - Fee Related CN105165874B (en) | 2013-07-03 | 2013-07-03 | Synergistic herbicide compositions |
| CN201510594713.XA Expired - Fee Related CN105165869B (en) | 2013-07-03 | 2013-07-03 | Synergistic herbicide compositions |
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| JP6545161B2 (en) * | 2013-10-17 | 2019-07-17 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | Herbicidal composition comprising an ACC inhibitor |
| TW201620384A (en) * | 2014-04-28 | 2016-06-16 | 陶氏農業科學公司 | Synergistic weed control from applications of HALOXYFOP and ALS inhibitor herbicides |
| CN104430443A (en) * | 2014-11-19 | 2015-03-25 | 西安近代化学研究所 | Sulfometuron methyl.fluazifop-p-butyl water dispersible granule |
| CN104381286A (en) * | 2014-12-16 | 2015-03-04 | 北京燕化永乐生物科技股份有限公司 | Weeding composition |
| CN104996446A (en) * | 2015-06-03 | 2015-10-28 | 赵志平 | Compound herbicide used for wheat field |
| CN106561694A (en) * | 2016-11-04 | 2017-04-19 | 东莞市联洲知识产权运营管理有限公司 | Compound herbicide used for soybean field |
| GB2562072B (en) * | 2017-05-03 | 2019-11-13 | Rotam Agrochem Int Co Ltd | Herbicidal composition and method for controlling plant growth |
| CN109497059B (en) * | 2018-12-26 | 2021-06-15 | 江苏丰山集团股份有限公司 | A kind of herbicidal composition containing flufensulfuron and preparation method thereof |
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| CN105165868B (en) | 2017-06-16 |
| CN105165867A (en) | 2015-12-23 |
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| CN105165870B (en) | 2017-08-08 |
| CN105165866B (en) | 2017-08-08 |
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