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CN1050753C - wound healing agent - Google Patents

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CN1050753C
CN1050753C CN93104920A CN93104920A CN1050753C CN 1050753 C CN1050753 C CN 1050753C CN 93104920 A CN93104920 A CN 93104920A CN 93104920 A CN93104920 A CN 93104920A CN 1050753 C CN1050753 C CN 1050753C
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wound healing
wounds
healing agent
present
wound
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CN1082912A (en
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陈余元
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Abstract

The invention relates to a wound healing agent for treating various intractable wounds, which is a medicament prepared from lithospermum, sargentgloryvine stem, giant knotweed rhizome, wild grape root, salvia miltiorrhiza and pomegranate bark. It has special curative effect on replantation of severed finger (toe), operation for remaining broken finger (toe) and new wound surface which is not broken yet due to scald; it can be substituted for rivanol (rivanol).

Description

创口愈合剂wound healing agent

本发明涉及一种有含有细菌性抗原的医药制品,特别是一种将中草药放在药用乙醇中浸泡,提炼其有效成份精制而成的创口愈合剂。The invention relates to a pharmaceutical product containing bacterial antigens, in particular to a wound healing agent obtained by soaking Chinese herbal medicine in medicinal ethanol and extracting its active ingredients.

目前,西医对创口医疗一般采用常规消毒后敷以利凡诺(RIV-ANOLUM)‰浸液纱布或纱布条塞入创口内,有的也采用抗生素软膏、硼酸软膏或鱼石脂软膏、消肿止痛等药物治疗,主要视不同创口性质而定,但对于受结核杆菌或金黄色葡萄球菌侵袭引起的顽固性创口,如结核性瘘管、下肢溃疡大面积创口等,采用西药外科药物外敷或药纱条内塞,很难达到理想疗效,而且疗效慢。At present, Western medicine generally adopts routine disinfection for wound treatment and then applies RIV-ANOLUM ‰ soaked gauze or gauze strips into the wound, and some also use antibiotic ointment, boric acid ointment or ichthyol ointment to reduce swelling and relieve pain, etc. Drug treatment mainly depends on the nature of different wounds, but for refractory wounds caused by Mycobacterium tuberculosis or Staphylococcus aureus, such as tuberculous fistula, large-area wounds of lower extremity ulcers, external application of western medicine surgical drugs or internal medicine gauze Blockage, it is difficult to achieve the desired curative effect, and the curative effect is slow.

由浙江省中医协会主办的《中医报》1986年第13期上介绍了一味治疗骨髓炎的临床报道,它用野葡萄根煎剂口服,并将其浸出液浸纱条外治骨髓炎,其不足之处:1.由于顽固性创口大多发生在阴湿或缺乏肌肉部位,用单味野葡萄根浸液浸纱条进行治疗对创口收敛慢;2.用于治疗对其它细菌如结核杆菌侵袭引起的创口效果差。On the 13th issue of 1986, the "Chinese Medicine News" sponsored by Zhejiang Association of Traditional Chinese Medicine introduced a clinical report on blindly treating osteomyelitis. Advantages: 1. Since most of the intractable wounds occur in wet or lacking muscles, soaking gauze strips with single-flavored wild grape root extract will slow the convergence of the wounds; 2. It is used to treat other bacteria such as Mycobacterium tuberculosis. The wound effect is poor.

由于上述实际情况,往往使顽固性创口迁延时间终成痼疾。Due to the above-mentioned actual situation, the protracted time of the intractable wound often becomes a chronic disease eventually.

本发明的目的是提供一种用于治疗多种顽固性刨口而且疗效快速的创口愈合剂。The purpose of the present invention is to provide a kind of wound healing agent which is used for treating various obstinate cuts and has fast curative effect.

为了达到上述目的,本发明采用由下述重量配比原料药物制成的药剂进行解决:将紫草5%-20%、红藤5%-20%、虎杖10%-40%、野葡萄根10%-40%、丹参10%-40%、石榴皮2%-20%组成的中草药一起浸泡制成,提炼其有效成份精制而成,其制剂成为一种治疗顽固性创口的创口愈合剂。In order to achieve the above object, the present invention adopts the medicament that is made of the following raw materials by weight ratio to solve the problem: comfrey 5%-20%, red vine 5%-20%, Polygonum cuspidatum 10%-40%, wild grape root 10%-40%, salvia miltiorrhiza 10%-40%, pomegranate peel 2%-20% are made by soaking Chinese herbal medicine together, extracting its active ingredients and refining, and its preparation becomes a wound healing agent for treating stubborn wounds.

本发明将野葡萄根、紫草、红藤、虎杖放在药用乙醇进行浸泡,提炼、精制而成,其制剂中的有效成份对各种细菌有广谱的抗菌作用;对金黄色葡萄菌极度敏感,对白色葡萄球菌、绿脓杆菌、脑膜炎球菌、伤寒杆菌、卡他球菌、甲型链球菌、福氏及宋氏痢疾杆菌,结核杆菌有抑菌作用,因此它能够用于治疗各种细菌侵袭引起的顽固性创口。本发明还采用了丹参、石榴皮中草药,因此,本发明还具有消肿、活血、收敛、生肌、促进新皮生长和骨骼再生的功能,特别对于治疗发生在阴湿或缺乏肌肉部位的顽固性创口,具有创口收敛快的特点。由于本发明的制剂中含有以上所述的中草药的有效成份,它们协同作用,加快了治愈的速度。本发明用于临床治疗210例,治愈率达100%。The present invention soaks wild grape roots, comfrey, red vine, and knotweed in medicinal ethanol, extracts and refines them. The active ingredients in the preparation have broad-spectrum antibacterial effects on various bacteria; Extremely sensitive, it has antibacterial effect on Staphylococcus albus, Pseudomonas aeruginosa, meningococcus, typhoid bacillus, catarrhal coccus, streptococcus flexneri and Shigella sonnei, tubercle bacillus, so it can be used to treat various Refractory wounds caused by a bacterial attack. The present invention also adopts Danshen and pomegranate peel Chinese herbal medicines. Therefore, the present invention also has the functions of reducing swelling, invigorating blood circulation, astringent, promoting muscle growth, promoting new skin growth and bone regeneration, especially for the treatment of recalcitrant diseases occurring in dampness or lack of muscle. Sexual wounds have the characteristics of rapid wound convergence. Because the preparation of the present invention contains the active ingredients of the above-mentioned Chinese herbal medicines, they act synergistically to speed up the healing process. The present invention is used for clinical treatment of 210 cases, and the cure rate reaches 100%.

本发明与已有技术相比具有如下优点:Compared with the prior art, the present invention has the following advantages:

1.有广谱的抗菌作用。1. It has broad-spectrum antibacterial effect.

2.由于本发明收湿性极强,不但能治疗暴露创口例如下肢溃疡、单纯性或带状泡疹、疖、疡、疽之创口,而且还能用于治疗阴湿部分渗出液特别多的湿浓性炎症,例如鼻炎症、颈部湿疹、中内耳炎(包括内耳结核性软骨炎)、腋下湿疹、阴囊湿疹、阴道炎、宫颈糜烂、肛门湿疹等多种疾病。2. Due to the extremely strong hygroscopicity of the present invention, it can not only treat exposed wounds such as lower extremity ulcers, simple or herpes zoster, furuncles, ulcers, and gangrene wounds, but also be used to treat yin and damp parts with a lot of exudate Concentrated inflammation, such as rhinitis, neck eczema, otitis media (including tuberculous chondritis of the inner ear), axillary eczema, scrotum eczema, vaginitis, cervical erosion, anal eczema and other diseases.

3.由于本发明采用了中草药浸泡精制而成的制剂,因此,它使用时能够采用西医的纱布块或纱布条浸液外敷或内塞治疗方法。3. Because the present invention has adopted the preparation that Chinese herbal medicine soaks and refines, therefore, can adopt the gauze block or gauze strip soaking liquid external application of western medicine or the treatment method of inner plug when it uses.

4.由于本发明收湿性强,又含有胶质,当制剂浸纱布多层,作为骨折药外敷时,干燥后紧贴创口或骨折部,能起到类似石膏绷带特有的固定作用。4. Because the present invention has strong hygroscopicity and contains colloid, when the preparation is soaked in multiple layers of gauze and applied externally as a fracture medicine, it will stick to the wound or fracture after drying, and can play a unique fixing effect similar to a plaster bandage.

5.由于本发明具有活血、生肌、促进新皮生长和骨骼生长的作用,对断指(趾)再殖和断指(趾)残段保留手术有特殊疗效。5. Because the present invention has the effects of invigorating blood circulation, promoting granulation, and promoting new skin growth and bone growth, it has special curative effects on the repopulation of amputated fingers (toes) and the operation of retaining the stumps of amputated fingers (toes).

6.对烫伤尚未破溃的新创面本发明有特殊疗效。6. The present invention has a special curative effect on fresh wounds that have not yet been ulcerated.

7.可取代利凡诺(RIVANOLUM)。7. Can replace Rivanol (RIVANOLUM).

下面结合实施例对本发明作进一步详细说明。The present invention is described in further detail below in conjunction with embodiment.

本发明将紫草、红滕、虎杖、野葡萄根、丹参、石榴皮六种成份按表1所示比例配成的中草药,放在药用乙醇中浸泡,浸泡一段时间后,提炼其有效成份精制而成,其制剂成为一种治疗多种顽固性创口的创口愈合剂。用该创口愈合剂采用纱布块或布条浸液外敷或内塞治疗方法用于临床治疗情况见表2。In the present invention, the Chinese herbal medicine made from six components of comfrey, red teng, knotweed, wild grape root, salvia miltiorrhiza, and pomegranate peel according to the ratio shown in Table 1 is soaked in medicinal ethanol, and after soaking for a period of time, its active ingredients are extracted Refined, its formulation becomes a wound-healing agent for a variety of recalcitrant wounds. See Table 2 for clinical treatment using the wound healing agent for external application or internal plugging of gauze pieces or strips of soaking liquid.

本发明各实施例的中草药成分配比(以总重量1kg计)The Chinese herbal medicine composition proportion (in total weight 1kg) of each embodiment of the present invention

                                                     表1      实施例成份 实施例一 实施例二 实施例三 实施例四     紫草   50g   50g   80g   200g     红滕   200g   100g   100g   50g     虎杖   100g   400g   200g   400g   野葡萄根   400g   150g   200g   100g     丹参   150g   100g   400g   180g    石榴皮   100g   200g   20g   70g     合计   1000g   1000g   1000g   1000g 各实施例用于临床的治疗效果Table 1 Example ingredients Embodiment one Embodiment two Embodiment Three Embodiment Four Comfrey 50g 50g 80g 200g Red Teng 200g 100g 100g 50g Knotweed 100g 400g 200g 400g wild grape root 400g 150g 200g 100g Danshen 150g 100g 400g 180g pomegranate peel 100g 200g 20g 70g total 1000g 1000g 1000g 1000g Each embodiment is used for clinical therapeutic effect

                                                                      表2     实施例项  目    实施例一     实施例二    实施例三    实施例四   治疗创口类  型: 瘘管、疖痈、疽、中内耳炎鼻炎、 下肢溃疡、阴道炎、阴囊湿疹、液下湿疹、宫颈糜烂 断指(趾)再殖、残指(趾)保留手术外敷 汤伤尚未破溃的新创面、带状包疹  治疗时间   半个月   七天左右   1个月左右     3-4天   治愈率    100%     100%     100%     100% Table 2 Example project Embodiment one Embodiment two Embodiment three Embodiment four Types of wounds treated: Fistula, furuncle, gangrene, otitis media rhinitis, Ulcers of lower extremities, vaginitis, eczema of the scrotum, subcutaneous eczema, cervical erosion Replantation of amputated fingers (toes), and external application of retained fingers (toes) Fresh wounds and herpes zoster on unbroken soup wounds Healing period half a month about seven days about 1 month 3 to 4 days cure rate 100% 100% 100% 100%

Claims (1)

1, a kind of Wound healing preparation is characterized in that it is the medicament of being made by following weight proportioning material medicine: Radix vitis romanetii 10%-40%, Radix Arnebiae (Radix Lithospermi) 5%-20%, Caulis Sargentodoxae 5%-20%, Rhizoma Polygoni Cuspidati 10%-40%, Radix Salviae Miltiorrhizae 10%-40% and Pericarpium Granati 2%-20%.
CN93104920A 1993-05-05 1993-05-05 wound healing agent Expired - Fee Related CN1050753C (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103055144A (en) * 2012-12-28 2013-04-24 青岛爱维互动信息技术有限公司 Patch for treating skin wounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1017299B (en) * 1988-12-23 1992-07-01 松下电器产业株式会社 Video tape recorder with TV system converter

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1017299B (en) * 1988-12-23 1992-07-01 松下电器产业株式会社 Video tape recorder with TV system converter

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
《四川中医》1988,6(10) 1988.10.31 张陈炎,野葡萄考 *
《河南中医》1986,(5) 1986.5.31 贾北平,郑州医药专修学校 *
《药学通报》1987,22(4) 1987.4.30 冯世栋,浙江鄞县人民医院 *

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