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CN105046111B - A kind of Amplitude integrated electroencephalogram result automatic recognition system - Google Patents

A kind of Amplitude integrated electroencephalogram result automatic recognition system Download PDF

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Publication number
CN105046111B
CN105046111B CN201510573753.6A CN201510573753A CN105046111B CN 105046111 B CN105046111 B CN 105046111B CN 201510573753 A CN201510573753 A CN 201510573753A CN 105046111 B CN105046111 B CN 105046111B
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database
electroencephalogram
amplitude
waveform
patient
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CN105046111A (en
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李晓梅
刘建红
李晓莺
朱法荣
刘向红
康丽丽
阎贝贝
郎玉洁
刘晨
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JINAN CHILDREN'S HOSPITAL
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JINAN CHILDREN'S HOSPITAL
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Abstract

The invention discloses a kind of Amplitude integrated electroencephalogram result automatic recognition system and methods;Including custom block for defining existing typical disease, data memory module is for storing corresponding disease data, the electroencephalogram data input that input module is used to diagnose, data acquisition module is used to obtain the data of input module input, analyses and comparison module is for diagnosing the data of patient, it is diagnosed to be matching for patient's Amplitude integrated electroencephalogram and which kind of disease, if all mismatched with all databases, so diagnosis report of output waveform exception, and result is conveyed to output unit.It can voluntarily identify Amplitude integrated electroencephalogram and provide diagnostic result, reduce the task of clinician, improve diagnosis and treatment efficiency.

Description

A kind of Amplitude integrated electroencephalogram result automatic recognition system
Technical field
The present invention relates to a kind of Amplitude integrated electroencephalogram result automatic recognition systems.
Background technology
The other Amplitude integrated electroencephalogram (writing a Chinese character in simplified form aEEG) of bed is the continuous recording reduced form of electroencephalogram, indicates function of brain cell The output of monitoring is as a result, at present in clinical position, the situation for reflecting brain function has been increasingly becoming neural electrophysiology The focus of attention, while as the doctors such as vast neonate department, Neurology being used to assess the objective mark of function of brain cell situation It is accurate.Compared with Routine Eeg (EEG), early diagnosis and Index for diagnosis sensibility higher of the aEEG for cerebral injury, while nothing Wound, direct, sensitive, easy to operate, amplitude is high, can non-volatile recording, graph direct, bedside operate do not delay children with serious disease rescue It treats, be not easy by biology or abiotic artifacts, be more convenient for clinical application and analysis.
Since the record time is long, waveform is more, therefore time-consuming for result reading, this work at present is completed by clinician, While busy clinical position, it is necessary to which the physician of patient is submitted in overtime work after reading result, this is apparent to aggravate The burden of its work has carved up time and time of having a rest that he can observe the infant state of an illness, has been highly detrimental to the work of clinician Make.
Invention content
The purpose of the present invention is exactly to solve the above-mentioned problems, to provide a kind of Amplitude integrated electroencephalogram result automatic identification system System, it can voluntarily identify Amplitude integrated electroencephalogram and provide diagnostic result, reduce the task of clinician, improve Diagnosis and treatment efficiency.
To achieve the goals above, the present invention adopts the following technical scheme that:
A kind of Amplitude integrated electroencephalogram result automatic recognition system, including:
Custom block integrates the up-and-down boundary value of electroencephalogram waveform for self-defined input normal amplitude, and typical The Amplitude integrated electroencephalogram oscillogram of patient;
Data memory module, including normal boundary database, neonatal seizure waveform database, neonatal hypoxic-ischemic Encephalopathy database, infantile spasms database and big rural area syndrome database, these databases are for analyses and comparison module tune With;Normal boundary database is used to store the up-and-down boundary value of the normal amplitude integration electroencephalogram waveform of custom block input;
Input module, the Amplitude integrated electroencephalogram waveform for inputting patient;
Data acquisition module, the Amplitude integrated electroencephalogram waveform of the patient for receiving input, and it is conveyed to analyses and comparison Module;
Analyses and comparison module, first extract patient Amplitude integrated electroencephalogram waveform up-and-down boundary and with normal boundary number It is compared according to the boundary in library, normal diagnosis report is generated if without departing from the boundary value;If exceeding the boundary value Other databases in then being stored with data memory module are identified one by one, are diagnosed to be patient's Amplitude integrated electroencephalogram and which kind of Disease matches, if all mismatched with all databases, the diagnosis report of output waveform exception, and by result It is conveyed to output unit;
Output unit, diagnostic result for receiving analyses and comparison module and by showing that equipment is shown.
The Wave anomaly includes due to different caused by intensive care unit wave interference, electrode delamination or malposition of electrode factor Ordinary wave shape, and remove neonatal seizure, hypoxic ischemic encephalopathy of newborn, infantile spasms and big these diseases of rural area syndrome Outer Amplitude integrated electroencephalogram.
The input module includes scanner and self-defined input module, and the amplitude that the scanner is used to scan patient is whole Scanning result is conveyed to analyses and comparison module, the self-defined input mould by syncerebrum electrograph oscillogram by data memory module Block is inputted the characteristic of the Amplitude integrated electroencephalogram oscillogram of patient by doctor, and is conveyed to also by data memory module Analyses and comparison module.
The analyses and comparison module, to neonatal seizure waveform database, hypoxic ischemic encephalopathy of newborn database, baby All oscillograms carry out two-stage one-dimensional wavelet transform respectively in youngster's spasm disease database and big rural area syndrome database, drop The resolution ratio of Image Sub-Band after low decomposition obtains the characteristic value of image using PCA methods;
Using the characteristic value of acquisition as the input layer of limited Boltzmann machine, using neonatal seizure waveform database, newly Raw youngster's hypoxie-ischemic encephalopathy database, infantile spasms database, big rural area syndrome database and unusual waveforms data Multiple oscillograms in library are trained limited Boltzmann machine, neonatal seizure waveform feature data after being trained, Hypoxic ischemic encephalopathy of newborn characteristic, infantile spasms characteristic, big rural area syndrome characteristic and exception Waveform feature data;
For the Amplitude integrated electroencephalogram waveform of the patient for the up-and-down boundary value for integrating electroencephalogram waveform beyond normal amplitude Figure input-bound Boltzmann machine is tested to obtain test result, the Amplitude integrated electroencephalogram that cannot be identified is diagnosed as different Ordinary wave shape.
A kind of Amplitude integrated electroencephalogram result automatic identifying method, including:
Self-defined input normal amplitude integrates the up-and-down boundary value of electroencephalogram waveform and the amplitude-integrated brain of typical patient Electrograph oscillogram;
By data or waveform, storage is lacked to normal boundary database, neonatal seizure waveform database, newborn accordingly Oxygen ischemic cerebral disease database, infantile spasms database and big rural area syndrome database, these databases are in next step Analysis call;The up-and-down boundary value that the normal amplitude of self-defined input integrates electroencephalogram waveform is stored to normal boundary data Library;
Input the Amplitude integrated electroencephalogram waveform of patient;
Receive the Amplitude integrated electroencephalogram waveform of the patient of input;
First extraction patient Amplitude integrated electroencephalogram waveform up-and-down boundary and with the boundary in normal boundary database It is compared, normal diagnosis report is generated if without departing from the boundary value;If beyond if the boundary value with other data Library identified one by one, matching for patient's Amplitude integrated electroencephalogram and which kind of disease is diagnosed to be, if with all databases All mismatch, then the diagnosis report of output waveform exception, and diagnosis report is exported;
Receive diagnosis report and by showing that equipment is shown.
It is carried out one by one with other databases when the up-and-down boundary of the Amplitude integrated electroencephalogram waveform of patient exceeds the boundary value Knowing method for distinguishing is:To neonatal seizure waveform database, hypoxic ischemic encephalopathy of newborn database, infantile spasms data All oscillograms carry out two-stage one-dimensional wavelet transform respectively in library and big rural area syndrome database, reduce image after decomposing The resolution ratio of subband obtains the characteristic value of image using PCA methods;
Using the characteristic value of acquisition as the input layer of limited Boltzmann machine, using neonatal seizure waveform database, newly Raw youngster's hypoxie-ischemic encephalopathy database, infantile spasms database, big rural area syndrome database and unusual waveforms data Multiple oscillograms in library are trained limited Boltzmann machine, neonatal seizure waveform feature data after being trained, Hypoxic ischemic encephalopathy of newborn characteristic, infantile spasms characteristic, big rural area syndrome characteristic and exception Waveform feature data;
For the Amplitude integrated electroencephalogram waveform of the patient for the up-and-down boundary value for integrating electroencephalogram waveform beyond normal amplitude Figure input-bound Boltzmann machine is tested to obtain test result, the Amplitude integrated electroencephalogram that cannot be identified is diagnosed as different Ordinary wave shape.
Beneficial effects of the present invention:
Patient report can be automatically analyzed and printed immediately after Amplitude integrated electroencephalogram by bed is finished, can solve in this way Doctor is put, the labour for saving out can go outpatient service or emergency treatment to see patient, be protruded instead to solve the masses to a certain extent The contradiction about 3 minutes consultation times reflected, doctor is more, and the patient that each doctor sees can be relatively smaller, then each Patient will obtain relatively longer Waiting time, and the satisfaction of patient can be obtained a degree of promotion, finally alleviate doctors and patients Contradiction will reduce the occurrence frequency for hindering the severe event that doctor kills doctor for a long time.
The Amplitude integrated electroencephalogram of common encephalopathy is trained by limited Boltzmann machine, hereby using limited Bohr Graceful machine carries out test identifying and diagnosing to the Amplitude integrated electroencephalogram of patient and goes out common disease, it is impossible to the amplitude-integrated brain electricity of identification Figure is diagnosed as unusual waveforms, and doctor only to these unusual waveforms carefully read, and greatly reduces the task amount of doctor.
Description of the drawings
Fig. 1 is the structural diagram of the present invention.
Specific implementation mode
The invention will be further described with embodiment below in conjunction with the accompanying drawings.
As shown in Figure 1, a kind of Amplitude integrated electroencephalogram result automatic recognition system, including:
Custom block integrates the up-and-down boundary value of electroencephalogram waveform for self-defined input normal amplitude, and typical The Amplitude integrated electroencephalogram oscillogram of patient;The Amplitude integrated electroencephalogram oscillogram of typical patient can also be by scanner by allusion quotation The oscillogram of type inputs;
Data memory module, including normal boundary database, neonatal seizure waveform database, neonatal hypoxic-ischemic Encephalopathy database, infantile spasms database and big rural area syndrome database, these databases are for analyses and comparison module tune With;Normal boundary database is used to store the up-and-down boundary value of the normal amplitude integration electroencephalogram waveform of custom block input;
Input module, the Amplitude integrated electroencephalogram waveform for inputting patient;
Data acquisition module, the Amplitude integrated electroencephalogram waveform of the patient for receiving input, and it is conveyed to analyses and comparison Module;
Analyses and comparison module, first extract patient Amplitude integrated electroencephalogram waveform up-and-down boundary and with normal boundary number It is compared according to the boundary in library, normal diagnosis report is generated if without departing from the boundary value;If exceeding the boundary value Other databases in then being stored with data memory module are identified one by one, are diagnosed to be patient's Amplitude integrated electroencephalogram and which kind of Disease matches, if all mismatched with all databases, the diagnosis report of output waveform exception, and by result It is conveyed to output unit;
Output unit, diagnostic result for receiving analyses and comparison module and by showing that equipment is shown.
The Wave anomaly includes since the serious wave interference in intensive care unit, electrode delamination or malposition of electrode factor cause Unusual waveforms, and except neonatal seizure, hypoxic ischemic encephalopathy of newborn, infantile spasms and big rural area syndrome these Amplitude integrated electroencephalogram outside disease.
The input module includes scanner and self-defined input module, and the amplitude that the scanner is used to scan patient is whole Scanning result is conveyed to analyses and comparison module, the self-defined input mould by syncerebrum electrograph oscillogram by data memory module Block is inputted the characteristic of the Amplitude integrated electroencephalogram oscillogram of patient by doctor, and is conveyed to also by data memory module Analyses and comparison module.
The analyses and comparison module, to neonatal seizure waveform database, hypoxic ischemic encephalopathy of newborn database, baby All oscillograms carry out two-stage one-dimensional wavelet transform respectively in youngster's spasm disease database and big rural area syndrome database, drop The resolution ratio of Image Sub-Band after low decomposition obtains the characteristic value of image using PCA methods;
Using the characteristic value of acquisition as the input layer of limited Boltzmann machine, using neonatal seizure waveform database, newly Raw youngster's hypoxie-ischemic encephalopathy database, infantile spasms database, big rural area syndrome database and unusual waveforms data Multiple oscillograms in library are trained limited Boltzmann machine, neonatal seizure waveform feature data after being trained, Hypoxic ischemic encephalopathy of newborn characteristic, infantile spasms characteristic, big rural area syndrome characteristic and exception Waveform feature data;
For the Amplitude integrated electroencephalogram waveform of the patient for the up-and-down boundary value for integrating electroencephalogram waveform beyond normal amplitude Figure input-bound Boltzmann machine is tested to obtain test result, which includes being diagnosed as neonatal seizure, new life Youngster's hypoxie-ischemic encephalopathy, infantile spasms or big rural area syndrome, are diagnosed as the Amplitude integrated electroencephalogram that cannot be identified Unusual waveforms.
The result being diagnosed to be all shown by display equipment, and doctor can be with for unusual waveforms after seeing diagnostic result Analyzed in more detail, and for be diagnosed as neonatal seizure, hypoxic ischemic encephalopathy of newborn, infantile spasms or Big rural area syndrome can check the whether correct of diagnosis again.
A kind of Amplitude integrated electroencephalogram result automatic identifying method, including:
Self-defined input normal amplitude integrates the up-and-down boundary value of electroencephalogram waveform and the amplitude-integrated brain of typical patient Electrograph oscillogram;
By data or waveform, storage is lacked to normal boundary database, neonatal seizure waveform database, newborn accordingly Oxygen ischemic cerebral disease database, infantile spasms database and big rural area syndrome database, these databases are in next step Analysis call;The up-and-down boundary value that the normal amplitude of self-defined input integrates electroencephalogram waveform is stored to normal boundary data Library;
Input the Amplitude integrated electroencephalogram waveform of patient;
Receive the Amplitude integrated electroencephalogram waveform of the patient of input;
First extraction patient Amplitude integrated electroencephalogram waveform up-and-down boundary and with the boundary in normal boundary database It is compared, normal diagnosis report is generated if without departing from the boundary value;If beyond if the boundary value with other data Library identified one by one, matching for patient's Amplitude integrated electroencephalogram and which kind of disease is diagnosed to be, if with all databases All mismatch, then the diagnosis report of output waveform exception, and diagnosis report is exported;
Receive diagnosis report and by showing that equipment is shown.
It is carried out one by one with other databases when the up-and-down boundary of the Amplitude integrated electroencephalogram waveform of patient exceeds the boundary value Knowing method for distinguishing is:To neonatal seizure waveform database, hypoxic ischemic encephalopathy of newborn database, infantile spasms data All oscillograms carry out two-stage one-dimensional wavelet transform respectively in library and big rural area syndrome database, reduce image after decomposing The resolution ratio of subband obtains the characteristic value of image using PCA methods;
Using the characteristic value of acquisition as the input layer of limited Boltzmann machine, using neonatal seizure waveform database, newly Raw youngster's hypoxie-ischemic encephalopathy database, infantile spasms database, big rural area syndrome database and unusual waveforms data Multiple oscillograms in library are trained limited Boltzmann machine, neonatal seizure waveform feature data after being trained, Hypoxic ischemic encephalopathy of newborn characteristic, infantile spasms characteristic, big rural area syndrome characteristic and exception Waveform feature data;
For the Amplitude integrated electroencephalogram waveform of the patient for the up-and-down boundary value for integrating electroencephalogram waveform beyond normal amplitude Figure input-bound Boltzmann machine is tested to obtain test result, the Amplitude integrated electroencephalogram that cannot be identified is diagnosed as different Ordinary wave shape.
Above-mentioned, although the foregoing specific embodiments of the present invention is described with reference to the accompanying drawings, not protects model to the present invention The limitation enclosed, those skilled in the art should understand that, based on the technical solutions of the present invention, those skilled in the art are not Need to make the creative labor the various modifications or changes that can be made still within protection scope of the present invention.

Claims (2)

1. a kind of Amplitude integrated electroencephalogram result automatic recognition system, characterized in that including:
Custom block integrates the up-and-down boundary value and typical patient of electroencephalogram waveform for self-defined input normal amplitude Amplitude integrated electroencephalogram oscillogram;
Data memory module, including normal boundary database, neonatal seizure waveform database, hypoxic ischemic encephalopathy of newborn Database, infantile spasms database and big rural area syndrome database, these databases are called for analyses and comparison module;Just Normal data boundary library is used to store the up-and-down boundary value of the normal amplitude integration electroencephalogram waveform of custom block input;
Input module, the Amplitude integrated electroencephalogram waveform for inputting patient;
Data acquisition module, the Amplitude integrated electroencephalogram waveform of the patient for receiving input, and it is conveyed to analyses and comparison module;
Analyses and comparison module, first extract patient Amplitude integrated electroencephalogram waveform up-and-down boundary and with normal boundary database In boundary be compared, normal diagnosis report is generated if without departing from the boundary value;If beyond if the boundary value with Other databases in data memory module storage are identified one by one, are diagnosed to be patient's Amplitude integrated electroencephalogram and which kind of disease Match, if all mismatched with all databases, the diagnosis report of output waveform exception, and result is conveyed To output unit;
Output unit, diagnostic result for receiving analyses and comparison module and by showing that equipment is shown;
The Wave anomaly includes due to extraordinary wave caused by intensive care unit wave interference, electrode delamination or malposition of electrode factor Shape, and in addition to neonatal seizure, hypoxic ischemic encephalopathy of newborn, infantile spasms and big these diseases of rural area syndrome Amplitude integrated electroencephalogram;
The analyses and comparison module, to neonatal seizure waveform database, hypoxic ischemic encephalopathy of newborn database, baby's convulsion All oscillograms carry out two-stage one-dimensional wavelet transform respectively in contraction disease database and big rural area syndrome database, reduce and divide The resolution ratio of Image Sub-Band after solution obtains the characteristic value of image using PCA methods;
Using the characteristic value of acquisition as the input layer of limited Boltzmann machine, neonatal seizure waveform database, newborn are utilized In hypoxie-ischemic encephalopathy database, infantile spasms database, big rural area syndrome database and unusual waveforms database Multiple oscillograms limited Boltzmann machine is trained, the neonatal seizure waveform feature data after being trained, new life Youngster's hypoxie-ischemic encephalopathy characteristic, infantile spasms characteristic, big rural area syndrome characteristic and unusual waveforms Characteristic;
It is defeated for the Amplitude integrated electroencephalogram oscillogram of the patient for the up-and-down boundary value for integrating electroencephalogram waveform beyond normal amplitude Enter limited Boltzmann machine to be tested to obtain test result, extraordinary wave is diagnosed as the Amplitude integrated electroencephalogram that cannot be identified Shape.
2. a kind of Amplitude integrated electroencephalogram result automatic recognition system as described in claim 1, characterized in that the input module Including scanner and self-defined input module, the scanner is used to scan the Amplitude integrated electroencephalogram oscillogram of patient, will sweep It retouches result and analyses and comparison module is conveyed to by data memory module, the self-defined input module is by doctor by the amplitude of patient The characteristic input of electroencephalogram oscillogram is integrated, and analyses and comparison module is conveyed to also by data memory module.
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