CN104920772A - A kind of anti-cavity chewing gum and its preparation method - Google Patents
A kind of anti-cavity chewing gum and its preparation method Download PDFInfo
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- CN104920772A CN104920772A CN201510277157.3A CN201510277157A CN104920772A CN 104920772 A CN104920772 A CN 104920772A CN 201510277157 A CN201510277157 A CN 201510277157A CN 104920772 A CN104920772 A CN 104920772A
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- Medicines Containing Plant Substances (AREA)
Abstract
本发明属于口腔保健食品制造技术领域,具体涉及一种用于牙齿防蛀保健的防蛀牙口香糖及其制备方法。一种防蛀牙口香糖,它是由以下重量份数的原料制成的:肉桂油0.5~2份;薄荷油0.3~1份;桉叶油0.1~0.5份;木糖醇3~10份;异麦芽糖醇20~30份;蜂胶0.1~0.5份;滑石粉5~10份;甘油4~8份;口香糖胶基40~90份。本发明还进一步加入中药成分。本发明制备得到的防蛀牙口香糖具有清热降火、清洁口腔、抑制口腔有害细菌、清新口气、保护牙齿、防治蛀牙的作用,还能有效的控制口臭和斑块的形成,对口腔疾病如牙齿肿痛、牙龈炎等起到很好的防治作用。The invention belongs to the technical field of oral health food manufacturing, and in particular relates to an anti-cavity chewing gum for tooth anti-moth health care and a preparation method thereof. An anti-cavity chewing gum, which is made of the following raw materials in parts by weight: 0.5-2 parts of cinnamon oil; 0.3-1 part of peppermint oil; 0.1-0.5 parts of eucalyptus oil; 3-10 parts of xylitol; 20-30 parts of maltitol; 0.1-0.5 parts of propolis; 5-10 parts of talcum powder; 4-8 parts of glycerin; 40-90 parts of chewing gum base. The present invention further adds Chinese medicinal ingredients. The anti-cavity chewing gum prepared by the invention has the functions of clearing heat and reducing fire, cleaning the oral cavity, inhibiting harmful bacteria in the oral cavity, refreshing breath, protecting teeth, and preventing and controlling tooth decay, and can also effectively control the formation of bad breath and plaque, and is effective for oral diseases such as tooth swelling. Pain, gingivitis, etc. play a very good role in prevention and treatment.
Description
技术领域 technical field
本发明属于口腔保健食品制造技术领域,具体涉及一种用于牙齿防蛀保健的防蛀牙口香糖及其制备方法。 The invention belongs to the technical field of oral health food manufacturing, and in particular relates to an anti-cavity chewing gum for tooth anti-moth health care and a preparation method thereof.
背景技术 Background technique
随着人民生活水平的普遍提高及饮食中糖含量及其摄入量的增加,使得龋病得以流行,尤其是儿童乳牙产生蛀牙更为明显,随着人口寿命的延长,老年人根面龋亦在增长,这些都严重影响人们的口腔和身体健康,从而严重影响人们的生活质量。龋齿是一种常见病、多发病,其发病率高,分布广,对人体危害大。经过科学家们不懈的努力,现在普遍认为细菌是龋齿发生的主要原因,其中变形链球菌是主要致病菌,其形成的菌斑粘附于牙齿表面,并在牙齿表面繁殖生长、产酸,腐蚀牙齿,最终形成龋齿。 With the general improvement of people's living standards and the increase of sugar content and intake in the diet, dental caries is prevalent, especially in children's deciduous teeth. With the prolongation of population life, root caries of the elderly is also increasing. In growth, these all seriously affect people's oral cavity and health, thereby seriously affecting people's quality of life. Dental caries is a kind of common disease, frequently-occurring disease, and its sickness rate is high, and distribution is wide, and it is very harmful to human body. After the unremitting efforts of scientists, it is now generally believed that bacteria are the main cause of dental caries, among which Streptococcus mutans is the main pathogenic bacteria, the plaque formed by it adheres to the tooth surface, and reproduces and grows on the tooth surface, produces acid, corrodes teeth, and eventually caries.
目前,人们保护牙齿的方法几乎通过刷牙来实现的。但刷牙是需要一定场所和用具的,是很不方便的,即使有条件刷牙的人也没几个每天中午饭后刷牙的。口香糖属于糖果中的一类,它主要是由甜昧剂、胶基和香料和其他辅料为原料机械加工而成,它具有清洁口腔、保护牙齿的作用,因此,口香糖越来越受人们喜爱。 At present, people's method of protecting teeth is almost achieved by brushing teeth. But brushing teeth requires a certain place and utensils, which is very inconvenient. Even those who have the conditions to brush their teeth do not brush their teeth after lunch every day. Chewing gum belongs to a class in candy, and it is mainly made of sweetener, gum base, spices and other auxiliary materials as raw material mechanical processing, and it has the effect of cleaning oral cavity, protecting teeth, therefore, chewing gum is more and more liked by people.
但现在市面上的口香糖在咀嚼时只能去除口腔中极少部分残留物和短暂的清新口气,因在咀嚼时它无法对牙齿及舌头表面产生摩擦作用,从而无法从根源上清洁口腔,达到与刷牙等同的效果。口香糖虽然有一定清洁牙齿的作用,但由于其中的甜味剂多使用砂糖等,由于砂糖所含热量较高,容易引起肥胖或导致血糖升高,引起龋齿等口腔疾病的毛病,而为了增加口香糖的香味,在口香糖中经常添加香料,然而添加的大多数香料对人体也没有任何益处 ,因此生产含有低热量甜味剂并具有保护牙齿、防蛀牙作用的口香糖,成为口香糖生产领域急需解决的问题。 But the chewing gum on the market can only remove a very small part of the residue in the mouth and a short-term fresh breath when chewing, because it cannot produce friction on the surface of the teeth and tongue when chewing, so it cannot clean the mouth from the root. Same effect as brushing your teeth. Although chewing gum has a certain effect of cleaning teeth, because the sweeteners in it use granulated sugar, etc., because granulated sugar contains high calories, it is easy to cause obesity or increase blood sugar, causing dental caries and other oral diseases, and in order to increase chewing gum. Fragrances are often added to chewing gum. However, most of the added spices are not beneficial to the human body. Therefore, the production of chewing gum that contains low-calorie sweeteners and has the effect of protecting teeth and preventing tooth decay has become an urgent problem in the field of chewing gum production. .
检索到相关的专利如下: The relevant patents retrieved are as follows:
1、中国专利,名称:一种赤藓糖醇口香糖 申请号 200710014917.7 申请(专利权)人: 山东保龄宝生物技术有限公司 摘要:一种赤藓糖醇口香糖,它是由以下原料按重量份之比制成的,栀子花提取物5-20份,维生素C l-5份,维生素E 1-5份,蒲公英5-20份;赤藓糖醇20-40份,聚葡萄糖l0-30份,口香糖胶基l0-40份,蜂蜜l-5份。 本发明的制备方法是:a.原料预备。b.胶基烘软。c.搅拌混合。本发明不但能清洁口腔、防治发生口腔疾病,还具有清热解毒、不被人体代谢,具有减肥、祛痘的作用。 1. Chinese patent, title: Erythritol chewing gum Application number 200710014917.7 Applicant (patent) person: Shandong Baolingbao Biotechnology Co., Ltd. Abstract: An erythritol chewing gum, which is made of the following raw materials in parts by weight 5-20 parts of gardenia extract, 1-5 parts of vitamin C, 1-5 parts of vitamin E, 5-20 parts of dandelion; 20-40 parts of erythritol, 10-30 parts of polydextrose 10-40 parts of chewing gum base, 1-5 parts of honey. The preparation method of the present invention is: a. Raw material preparation. b. The gum base is baked soft. c. Stir to combine. The invention can not only clean the oral cavity and prevent and treat oral diseases, but also has the functions of clearing away heat and detoxifying, not being metabolized by the human body, and having the functions of losing weight and removing acne.
2、中国专利,名称:抗龋齿口香糖及其制备方法 申请号 200410051502.3 申请(专利权)人: 珠海百奥生物技术有限公司 摘要: 一种抗龋齿口香糖及其制备方法,旨在提供一种使用方便、高效、口感好的抗龋齿口香糖及其制备方法。 该抗龋齿口香糖由抗龋齿卵黄抗体、胶基、木糖醇、阿拉伯胶、甘露醇、柠檬酸、卵磷脂和食用香精制成,其制备方法是,先针对引起龋齿的主要病原菌——变形链球菌进行分析研究而制成抗龋齿卵黄抗体,然后再制成口香糖,该制备方法卫生、环保、方便、成本低。 本发明可应用于口腔抗龋、治龋领域。 2. Chinese patent, title: Anti-caries chewing gum and its preparation method Application No. 200410051502.3 Applicant (patent) person: Zhuhai Biotech Co., Ltd. Abstract: An anti-caries chewing gum and its preparation method, aiming at providing an easy-to-use An anti-caries chewing gum with high efficiency and good taste and a preparation method thereof. The anti-caries chewing gum is made of anti-caries yolk antibody, gum base, xylitol, gum arabic, mannitol, citric acid, lecithin and food flavors. The anti-caries yolk antibody is prepared by analyzing and studying the cocci, and then the chewing gum is prepared. The preparation method is hygienic, environmentally friendly, convenient and low in cost. The present invention can be applied to the fields of anti-caries and treatment of dental caries.
发明内容 Contents of the invention
本发明的目的在于提供一种防蛀牙口香糖及其制备方法,该防蛀牙口香糖将肉桂油添加到口香糖中,具有杀灭皮肤和口腔中有害病菌的作用;不采用砂糖为甜味剂,采用木糖醇和异麦芽糖醇作为甜味剂能保护牙齿、防治蛀牙,并加入中药成分,具有清热降火、清洁口腔、抑制口腔有害细菌、清新口气、保护牙齿、防治蛀牙的作用,还能有效的控制口臭和斑块的形成,对口腔疾病如牙齿肿痛、牙龈炎等起到很好的防治作用。 The object of the present invention is to provide an anti-cavity chewing gum and its preparation method. The anti-cavity chewing gum adds cinnamon oil to the chewing gum, which has the effect of killing harmful bacteria in the skin and oral cavity; instead of using sugar as a sweetener, wood As sweeteners, sugar alcohol and isomalt can protect teeth and prevent tooth decay, and add traditional Chinese medicine ingredients, which have the functions of clearing away heat and reducing fire, cleaning the mouth, inhibiting harmful bacteria in the mouth, refreshing breath, protecting teeth, and preventing tooth decay. Bad breath and the formation of plaque play a very good role in the prevention and treatment of oral diseases such as tooth swelling and gingivitis.
为了实现本发明的目的,本发明采用如下技术方案: In order to realize the purpose of the present invention, the present invention adopts following technical scheme:
一种防蛀牙口香糖,其特征在于,它是由以下重量份数的原料制成的: An anti-cavity chewing gum is characterized in that it is made of the following raw materials in parts by weight:
肉桂油0.5~2份;薄荷油 0.3~1份;桉叶油0.1~0.5份;木糖醇 3~10份;异麦芽糖醇20~30份;蜂胶0.1~0.5份;滑石粉5~10份;甘油4~8份;口香糖胶基40~90份; 0.5-2 parts of cinnamon oil; 0.3-1 part of peppermint oil; 0.1-0.5 parts of eucalyptus oil; 3-10 parts of xylitol; 20-30 parts of isomalt; 0.1-0.5 parts of propolis; 5-10 parts of talcum powder ; 4-8 parts of glycerin; 40-90 parts of chewing gum base;
上述的防蛀牙口香糖,还进一步加入中药成分,其重量份数为总量的 2~3份。 The above-mentioned anti-cavity chewing gum further adds traditional Chinese medicine components, and its parts by weight are 2 to 3 parts of the total amount.
上述的中药成分包括以下重量份数的组分:锦灯笼10~17份,青黛10~15份,细辛12~18份,红天葵2~5份,甘草4~8份,五倍子3~5份。 The above-mentioned traditional Chinese medicine ingredients include the following components in parts by weight: 10-17 parts of Jinlantern, 10-15 parts of Qingdai, 12-18 parts of Asarum, 2-5 parts of Red Heliotrope, 4-8 parts of Glycyrrhizae, 3-3 parts of Gallnut 5 servings.
上述的蜂胶是粉碎成150~200目的蜂胶粉末。 The above-mentioned propolis is crushed into 150-200 mesh propolis powder.
上述的防蛀牙口香糖的制备方法步骤如下: The steps of the preparation method of the above-mentioned anti-cavity chewing gum are as follows:
(1)用粉碎机分别将中药成分中的各个组分粉碎成60~90目,然后按重量份数取已粉碎的各个组分充分混合均匀,得到混合物,往混合物中加入醇浓度为70%~90%乙醇,乙醇的加入量为混合物体积的2~3倍,在70~90℃下回流4~6小时,过滤,得到回流液; (1) Use a pulverizer to pulverize each component of the traditional Chinese medicine into 60-90 meshes, and then take the pulverized components by weight and mix them well to obtain a mixture. Add alcohol concentration of 70% to the mixture ~90% ethanol, the amount of ethanol added is 2 to 3 times the volume of the mixture, reflux at 70~90°C for 4~6 hours, filter to obtain the reflux liquid;
(2)将回流液进行减压蒸馏,去除乙醇,获得固状物体,将固状物体进行干燥然后粉碎成150~200目粉末,得到用于制备防蛀牙口香糖的中药成分; (2) Distill the reflux liquid under reduced pressure to remove ethanol to obtain a solid object, dry the solid object and then pulverize it into 150-200 mesh powder to obtain the traditional Chinese medicine ingredients used for preparing anti-cavity chewing gum;
(3)将重量份数的口香糖胶基在70~85℃下加热1~2小时,然后按配比加入重量份数的中药成分、肉桂油、薄荷油 、桉叶油、木糖醇、异麦芽糖醇、蜂胶、滑石粉和甘油,充分混合,搅拌均匀,得到混合物; (3) Heat the chewing gum base in parts by weight at 70-85°C for 1-2 hours, then add traditional Chinese medicine ingredients, cinnamon oil, peppermint oil, eucalyptus oil, xylitol, and isomaltose in parts by weight Alcohol, propolis, talcum powder and glycerin, fully mixed, stirred evenly, to obtain a mixture;
(4)将得到的混合物挤压成块、降温至常温,然后进行压片、分切,包装,即可得到防蛀牙口香糖。 (4) Extrude the obtained mixture into blocks, cool down to normal temperature, and then perform tableting, cutting, and packaging to obtain anti-cavity chewing gum.
上述的肉桂油为樟科植物肉桂Cinnamomum cassia Presl 的干燥枝、叶经水蒸气蒸镏得到的挥发油。肉桂油广泛用于医药、食品及轻化工业。历代本草中均列为上品,认为有补火助阳,引火归源,散寒止痛,活血通经等作用。中医作为治阳痿,宫冷,腰膝冷痛,肾虚作喘,阳虚眩晕,目赤咽痛,心腹冷痛,虚寒吐泻,寒疝,奔豚,经闭,痛经药使用。现代研究显示,肉桂具有抗菌、抗肿瘤、抗溃疡、解热、镇痛解痉、壮阳、杀虫等多种作用。肉桂油具有天然驱虫杀虫、杀霉菌的功效,又不会污染食物。肉桂油对常见细菌(大肠杆菌、沙门氏菌、枯草芽孢杆菌、苏云金杆菌等),酵母菌(啤酒酵母、面包酵母等)、霉菌(黑曲霉、米曲霉、黄曲霉、青霉、木霉、毛霉、根霉等)均具有很强的抑制作用,将肉桂油添加到口香糖中,具有杀灭皮肤和口腔中有害病菌的作用。 The above-mentioned cinnamon oil is the volatile oil obtained by steam distillation of the dried branches and leaves of Cinnamomum cassia Presl. Cinnamon oil is widely used in medicine, food and light chemical industry. All herbal medicines of past dynasties are listed as top grade, and it is believed that it has the effects of nourishing fire and supporting yang, drawing fire back to its source, dispelling cold and relieving pain, promoting blood circulation and stimulating menstruation. Traditional Chinese medicine is used as a medicine for treating impotence, cold palace, cold waist and knee pain, shortness of breath due to kidney deficiency, dizziness due to yang deficiency, red eyes and sore throat, cold pain in trusted subordinates, vomiting and diarrhea due to deficiency and cold, cold hernia, running dolphins, amenorrhea, and dysmenorrhea. Modern research shows that cinnamon has various functions such as antibacterial, antitumor, antiulcer, antipyretic, analgesic and antispasmodic, aphrodisiac, and insecticide. Cinnamon oil has the effect of naturally repelling insects, killing fungi, and will not contaminate food. Cinnamon oil is effective against common bacteria (Escherichia coli, Salmonella, Bacillus subtilis, Bacillus thuringiensis, etc.), yeasts (brewer's yeast, baker's yeast, etc.), molds (Aspergillus niger, Aspergillus oryzae, Aspergillus flavus, Penicillium, Trichoderma, Mucor , Rhizopus, etc.) all have a strong inhibitory effect. Adding cinnamon oil to chewing gum has the effect of killing harmful bacteria in the skin and mouth.
上述的中药成分中,所述的锦灯笼拉丁学名为:Physalis alkekengi L.var.franchetii别称:挂金灯、灯笼果、红灯笼、姑娘、金姑娘、金灯、姑碾儿、咕鸟;锦灯笼为茄科酸浆属多年生宿根草本植物,药用果实,有清热解毒、利咽、化痰、利尿、疏肝和镇咳利尿的功能。主治肝气不舒,肾炎,肝炎;坏血病、痰热咳嗽。锦灯笼植株作为中药,含酸浆醇(physanol)A、B;种子中含禾本甾醇(gramisterol)、钝叶醇(obtusifoliol)、环木菠萝烷醇(cycloartanol)、环木菠萝烯醇(cycloartenol)等化学成分。性寒,味苦,主治肺热喉痛,肺病,腮腺炎,热疝,血淋;外治皮肤疮肿,天疱疮,牙龈肿痛。有清热解毒,利咽,化痰,利尿之功效。苗、叶、茎、根均可入药,味苦、寒、无毒。苗、叶、茎含酸浆苦味素A0.02%、B0.002%、C(脱氧酸浆苦味素A)。味酸、苦,性寒,有清热解毒、利尿功能。可治咳嗽、黄疸、疟疾、水肿、疔疮、丹毒等。根味苦、性寒,有清热、利水功能。可治疟疾、黄疸、疝气。籽酸、平、无毒。膨大的宿存萼可入药,有清凉、化痰、镇咳、利尿之功效。果味酸甜,略有苦味,果皮味极苦,两者皆可入药,锦灯果在中药上称“老子”,可清热解毒、清痰止咳,治疗慢性气管炎。 Among the above-mentioned traditional Chinese medicine ingredients, the Latin scientific name of the brocade lantern is: Physalis alkekengi L.var.franchetii Another name: Hanging Golden Lantern, Lantern Fruit, Red Lantern, Girl, Golden Girl, Golden Lantern, Gu Nianer, Cuckoo; Jin Deng Lantern is a perennial herbaceous plant of Physalis genus in the Solanaceae Physalis family. It is a medicinal fruit and has the functions of clearing away heat and detoxification, relieving sore throat, resolving phlegm, diuresis, soothing the liver and antitussive and diuretic. Indications for discomfort of liver qi, nephritis, hepatitis; scurvy, cough due to phlegm heat. As a traditional Chinese medicine, the plant of Jinlan lantern contains physanol A and B; the seeds contain gramisterol , obtusifoliol , cycloartanol , cycloartenol ) and other chemical components. Cold in nature, bitter in taste, mainly used for lung heat and sore throat, lung disease, mumps, hot hernia, bloody stranguria; externally for skin sores, pemphigus, gingival swelling and pain. It has the effects of clearing away heat and detoxification, relieving sore throat, reducing phlegm and diuresis. Seedlings, leaves, stems and roots can be used as medicine, bitter, cold and non-toxic. Seedlings, leaves, and stems contain physalis bitterin A0.02%, B0.002%, C (deoxyphysalis bitterin A). Sour, bitter, cold in nature, has heat-clearing, detoxifying and diuretic functions. It can cure cough, jaundice, malaria, edema, boils, erysipelas, etc. The root is bitter in taste and cold in nature, and has the functions of clearing away heat and diuresis. Can cure malaria, jaundice, hernia. Seed acid, flat, non-toxic. The enlarged persistent calyx can be used as medicine, which has the effects of cooling, reducing phlegm, antitussive and diuretic. The fruit tastes sweet and sour, slightly bitter, and the peel tastes extremely bitter. Both of them can be used as medicine. Jindeng fruit is called "Laozi" in traditional Chinese medicine. It can clear away heat and detoxify, clear phlegm and relieve cough, and treat chronic bronchitis.
所述的青黛:为爵床科植物马蓝Baphicacanthus cusia(Nees)Bremek.蓼科植物蓼蓝Polygonum tinctorium Ait或十字花科植物菘蓝Isatis indigotica Fort。的叶或茎叶经加工制得的干燥粉末、团块或颗粒。别称:靛花、青蛤粉、青缸花、蓝露、淀花、靛沫花;性味咸寒,有清热解毒,凉血消斑,泻火定惊等功效。其主要用于温病热盛,斑疹,吐血、咯血,咽痛口疮,小儿惊痫,疮肿,丹毒,蛇虫咬伤等。《开宝本草》:“主解诸药毒,小儿诸热,惊厥发热,天行头痛寒热,煎水研服之。亦摩敷热疮、恶肿、金疮、下血、蛇犬等毒。4《本草蒙筌》:“泻肝,止暴注,消膈上痰水,驱时疫头痛,敛伤寒赤斑,水调服之。” Said Qingdai: Baphicacanthus cusia (Nees) Bremek. Polygonum tinctorium Ait or Isatis indigotica Fort . Dry powder, agglomerates or granules obtained by processing leaves or stems and leaves. Other names: Indigo flower, green clam powder, blue pot flower, blue dew, dian flower, indigo flower; salty and cold in nature, has the effects of clearing heat and detoxifying, cooling blood and eliminating spots, purging fire and calming convulsions. It is mainly used for febrile disease with heat exuberance, macule rash, hematemesis, hemoptysis, sore throat, aphtha, epilepsy in children, sores, erysipelas, snake and insect bites, etc. "Kaibao Materia Medica": "It mainly relieves the poison of various medicines. For children with various fevers, convulsions and fever, Tianxing headache with cold and heat, decoct it in water and grind it. It is also rubbed and applied to heat sores, malignant swellings, gold sores, blood, snakes and other poisons. 4 "Materia Medica Mengguan": "Purge the liver, relieve violent injections, eliminate phlegm on the diaphragm, drive away epidemic headaches, restrain typhoid red spots, and take it with water. "
《本草纲目》:“去热烦,吐血,咯血,斑疮,阴疮,杀恶虫。”《本草述》:“治中风、头风、胁痛、瘛、颤振、眩晕、咳嗽、久嗽、呕吐、舌衄、咳嗽血,寒疝。”青黛对羊毛状小孢子菌、断发癣、石膏样小孢子菌、紫色癣菌、石膏样癣菌、红色癣菌、絮状表皮癣菌等均有较强的抑制作用,能够治疗牙龈炎。 "Compendium of Materia Medica": "Removing heat and vexation, vomiting blood, hemoptysis, spot sores, genital sores, and killing pests." Cough, vomiting, tongue bleed, cough blood, cold colic." Indigo Daisy against Microsporum lanoides, Trichomonas gypsum, Microsporum gypsum, Violet phyton, Trichophyton gypsum, Trichophyton rubrum, Epidermophyton flocculus etc. have a strong inhibitory effect and can treat gingivitis.
所述的细辛,别名:华细辛、盆草细辛,拉丁文名:Asarum sieboldii Miq. 马兜铃科、细辛属多年生草本;细辛作为药用植物,始载秦汉《神农本草经》,《神农本草经》将其列为上品。辽细辛根细、色灰黄、叶色绿,味辛辣麻舌。性温,有小毒。归心、肺、肾经。有祛风,散寒,温肺、行水,开窍、解热镇痛的作用,具有抗菌、消炎、止血、镇痛等疗效。治风寒头痛,鼻渊,齿痛,痰饮咳逆,风湿痹痛。此外,细辛还具有抗炎免疫、局部麻醉、提高新陈代谢、抗菌作用,亦可用于肿瘤患者化疗和放疗所致的白细胞减少。镇静、镇痛作用细辛挥发油有明显的中枢抑制作用,小剂量可使动物安静、驯服、自主活动减少;大剂量可使动物睡眠,并有明显的抗惊厥作用。细辛煎剂灌服也有镇痛作用。其较强的镇痛作用为其治疗头身痛、牙痛等的重要药理学基础。.抗炎、免疫抑制和抗变态反应细辛挥发油灌服或注射均有明显的抗炎作用。.抗菌、抗病毒作用细辛醇浸剂、挥发油等对革兰阳性菌、枯草杆菌和伤寒杆菌有一定的体外抑制作用,煎剂对结核杆菌和伤寒杆菌亦有抑制作用。细辛挥发油对多种真菌如黄曲霉菌、黑曲霉菌、白色念珠菌等均有抑制作用,抗菌的有效成分为黄樟醚。α-细辛醚有抑制呼吸道合胞病毒增殖的作用。 Said Asarum, alias: Hua Asarum, Pontcao Asarum, Latin name: Asarum sieboldii Miq. Aristolochiaceae, Asarum is a perennial herb; Asarum is used as a medicinal plant, and it was first recorded in "Shen Nong’s Herbal Classic" in Qin and Han Dynasties ", "Shen Nong's Materia Medica" listed it as the top grade. Liao Asarum has thin roots, grayish-yellow color, green leaves, spicy and numb tongue. Warm in nature, slightly poisonous. Guixin, lung, kidney channel. It has the effects of expelling wind, dispelling cold, warming the lungs, promoting water flow, resuscitation, antipyretic and analgesic, and has antibacterial, anti-inflammatory, hemostasis, analgesic and other curative effects. Control wind-cold headache, sinusitis, toothache, phlegm retention and cough, rheumatic arthralgia. In addition, Asarum also has anti-inflammatory immunity, local anesthesia, increased metabolism, and antibacterial effects, and can also be used for leukopenia caused by chemotherapy and radiotherapy in tumor patients. Sedative and analgesic effects Asarum volatile oil has obvious central inhibitory effects, small doses can make animals quiet, tame, and reduce autonomous activities; large doses can make animals sleep, and have obvious anticonvulsant effects. Oral administration of Asarum decoction also has analgesic effect. Its strong analgesic effect is an important pharmacological basis for its treatment of head and body pain and toothache. .Anti-inflammation, immunosuppression and anti-allergic Asarum volatile oil has obvious anti-inflammatory effect through perfusion or injection. . Antibacterial and antiviral effects. Asarone infusion and volatile oil have certain in vitro inhibitory effects on Gram-positive bacteria, Bacillus subtilis and Salmonella typhi, and decoctions also have inhibitory effects on Mycobacterium tuberculosis and Salmonella typhi. Asarum volatile oil has inhibitory effect on various fungi such as Aspergillus flavus, Aspergillus niger, Candida albicans, etc., and the antibacterial active ingredient is safrole. α-Asarone can inhibit the proliferation of respiratory syncytial virus.
所述的红天葵(学名:Begonia fimbristipula)又名紫背天葵、红叶、散血子、 The red geranium (scientific name: Begonia fimbristipula ) is also known as purple-backed geranium, red leaves, scattered blood,
龙虎叶、夜渡红、红水葵,是一种中药材。为秋海棠科植物紫背天葵的球茎或全株。功用主治清热凉血,活血解毒。治暑热高烧,肺热咳嗽,咯血,跌打扭伤,血瘀疼痛,疮毒疥癣,水火烫伤。 性味甘涩,凉,无毒。广州部队《常用中草药手册》:"清热解毒,润燥止咳,散瘀消肿。治外感高热。中暑发烧,肺热咳嗽,跌打肿痛。鲜品捣烂,可敷恶疮疔毒。"《常用中草药彩色图谱》:"治肺炎咳嗽,咯血,慢性支气管炎。"《广西实用中草药新选》:"凉血活血,消炎止痛。主治咯血,血瘀腹痛,扭挫伤,骨折,汤火伤,癣疥。"。 Dragon and tiger leaves, Yeduhong, and red water sunflower are a kind of traditional Chinese medicine. It is the bulb or whole plant of the Begoniaceae plant. Function cures mainly clearing heat and cooling blood, promoting blood circulation and detoxification. Control summer heat and high fever, cough due to lung heat, hemoptysis, bruises, sprains, blood stasis pain, sores and scabies, water and fire burns. Sweet and astringent in nature and flavor, cool, non-toxic. "Handbook of Commonly Used Chinese Herbal Medicine" by the Guangzhou Army: "Clears heat and detoxifies, moistens dryness and relieves cough, dissipates blood stasis and reduces swelling. Treats exogenous high fever. Heatstroke fever, lung heat cough, bruises, swelling and pain. Fresh products are smashed and can be applied to malignant sores and furunculosis." "Color Atlas of Commonly Used Chinese Herbal Medicines": "Cure pneumonia, cough, hemoptysis, and chronic bronchitis." "New Selections of Practical Chinese Herbal Medicines in Guangxi": "Cooling blood and promoting blood circulation, reducing inflammation and relieving pain. Indications for hemoptysis, blood stasis, abdominal pain, sprains, fractures, soup burns, Ringworm Scabies.".
所述的甘草,拉丁学名:Glycyrrhiza uralensis Fisch.别名:国老、甜草、乌拉 The licorice, Latin scientific name: Glycyrrhiza uralensis Fisch . Alias: Guolao, sweet grass, Ula
尔甘草、甜根子。豆科、甘草属多年生草本,根与根状茎粗壮,是一种补益中草药。甘草含有多种化学成分,主要成分有甘草酸、甘草甙等。功能主治:清热解毒、祛痰止咳、脘腹等。甘草的药用价值有:1.用于心气虚,心悸怔忡,脉结代,以及脾胃气虚,倦怠乏力等。2.用于痈疽疮疡、咽喉肿痛等。可单用,内服或外敷,或配伍应用。痈疽疮疡,常与金银花、连翘等同用,共奏清热解毒之功;3.用于气喘咳嗽;4.用于胃痛、腹痛及腓肠肌挛急疼痛等 ;5. 甘草黄酮、甘草浸膏及甘草次酸均有明显的镇咳作用;祛痰作用也较显著,其作用强度为甘草酸>甘草黄酮>甘草浸膏。6. 甘草还有抗炎,抗过敏作用,能保护发炎的咽喉和气管粘膜。甘草浸膏和甘草酸对某些毒物有类似葡萄糖醛酸的解毒作用。 Licorice, sweet root. Legumes and licorice are perennial herbs with strong roots and rhizomes. They are a kind of tonic Chinese herbal medicine. Licorice contains a variety of chemical components, the main components are glycyrrhizic acid, glycyrrhizin and so on. Functions and indications: heat-clearing and toxic substances removing, eliminating phlegm and relieving cough, abdominal distension, etc. The medicinal value of licorice are: 1. For heart qi deficiency, palpitations, intermittent pulse, and spleen and stomach qi deficiency, fatigue and fatigue. 2. For carbuncle sores, sore throat and so on. It can be used alone, orally or externally, or in combination. Carbuncle sores, often used together with honeysuckle and forsythia to play the role of clearing away heat and detoxification; 3. For asthma and cough; 4. It is used for stomach pain, abdominal pain and gastrocnemius spasm acute pain, etc.; 5. Licorice flavonoids, licorice extract and glycyrrhetinic acid all have obvious antitussive effects; the expectorant effect is also more significant, and the intensity of action is glycyrrhizic acid > licorice flavonoids > licorice extract. 6. Licorice also has anti-inflammatory and anti-allergic effects, and can protect the inflamed throat and tracheal mucosa. Licorice extract and glycyrrhizic acid have a detoxification effect similar to glucuronic acid on certain poisons.
所述的五倍子,学名:Rhus chinensis Mill.,又名百虫仓、百药煎、棓子,中药材五倍子为漆树科植物盐肤木、青麸杨或红麸杨叶上的干燥虫瘿,主要由五倍子蚜寄生而形成。其性寒,味酸、涩,具有敛肺降火、涩肠止泻、敛汗止血、收湿敛疮等功效,主治肺虚久咳、久泻久痢、便血痔血、痈肿疮毒、皮肤湿烂等症。五倍子的药理作用:1. 收敛作用 五倍子含有鞣酸,有沉淀蛋白质的作用, 皮肤溃疡面、黏膜与其接触后,组织蛋白质即被凝固, 形成一层保护膜,起收敛作用, 同时小血管也被压迫收缩,血液凝结而呈止血作用,腺细胞的蛋白质被凝固引起分泌抑制, 使黏膜干燥,神经末梢蛋白质的沉淀, 可呈微弱的局部麻醉现象。五倍子中所含鞣酸对正常小肠运动无甚影响,但由于其收敛作用而减轻肠道炎症, 故可制止腹泻.2. 抗菌作用 体外试验表明:五倍子煎剂对金黄色葡萄球菌、乙型溶血性链球菌、肺炎球菌、绿脓杆菌、痢疾杆菌、炭疽杆菌、白喉杆菌、大肠杆菌、伤寒和副伤寒杆菌等均有明显的抑菌和杀菌作用。 Described Galla, scientific name: Rhus chinensis Mill., also known as Baichongcang, Baiyaojian, Gallozi, Chinese herbal medicine Galla is dry galls on the leaves of Anacardiaceae Saltwood, Populus chinensis or Populus chinensis, It is mainly formed by gall aphid parasitism. It is cold in nature, sour and astringent in taste, and has the effects of astringing the lungs and reducing fire, astringent intestines and diarrhea, astringing sweat to stop bleeding, dampness and sores, etc. , skin wet rot embolism. Pharmacological effects of Gallnut: 1. Astringent Gallnut contains tannic acid, which has the effect of precipitating protein. After skin ulcers and mucous membranes are in contact with it, the tissue protein is coagulated to form a protective film, which acts as astringent. At the same time, small blood vessels are also blocked. Compression and contraction, blood coagulation and hemostatic effect, coagulation of glandular cell protein causes secretion inhibition, drying of mucous membranes, precipitation of nerve ending protein, and weak local anesthesia. The tannic acid contained in gallnut has little effect on the normal small intestine movement, but because of its astringent effect, it can reduce intestinal inflammation, so it can stop diarrhea. 2. The in vitro test of antibacterial effect shows that Galla galla decoction is effective against Staphylococcus aureus, beta-hemolytic streptococcus, pneumococcus, Pseudomonas aeruginosa, Shigella, Bacillus anthracis, Bacillus diphtheria, Escherichia coli, typhoid and paratyphoid bacillus, etc. It has obvious antibacterial and bactericidal effects.
所述的蜂胶是蜜蜂从植物芽孢或树干上采集的树脂,将其混入其上腭腺、蜡腺的分泌物加工而成的一种具有芳香气味的胶状固体物。拉丁学名为:Colla Apis,是蜜蜂科动物中华蜜蜂等修补蜂巢所分泌的黄褐色或黑褐色的粘性物质,可入药。其性寒,味苦、辛,有润肤生肌,消炎止痛的功效,可治疗胃溃疡、口腔溃疡、烧烫伤、皮肤裂痛,防辐射 等病症;蜂胶乙醇浸出物100微克/毫升浓度对39种细菌中的25种和39种植物真菌中的20种都有抑制作用,其是对革兰氏阳性细菌和抗酸菌最为敏感。1%—10%的蜂胶醇或醚提取物对人类常见的真菌、癣菌、絮状癣菌、红色癣菌、铁锈色小孢子菌、石膏样小孢子菌、羊毛状小孢子菌、大脑状癣菌、石膏样癣菌、断发癣菌、紫色癣菌等都有抑制作用。对黄瓜花叶病毒、烟草斑点病毒、烟草坏死病毒和A型流感病毒都有较好的杀灭作用。能抑制疱疹病毒的繁殖和显著减轻牛痘病毒的感染;早在50年代,国外就应用蜂胶软膏成功地治疗了复发性口疮、口腔糜烂、溃疡等口腔疾病。蜂胶所含有的丰富而独特的生物活性物质,使其具有抗菌、消炎、止痒、抗氧化、增强免疫、降血糖、降血脂、抗肿瘤等多种功能,对人体有着广泛的医疗、保健作用。 The propolis is a colloidal solid with an aromatic smell, which is processed by mixing the resin collected by bees from plant spores or tree trunks into the secretions of their palate glands and wax glands. The Latin scientific name is: Colla Apis , which is a yellow-brown or dark-brown viscous substance secreted by Apis mellifera and other animals repairing the hive, which can be used as medicine. It is cold in nature, bitter in the mouth, pungent, has the effects of moistening skin and promoting granulation, anti-inflammatory and pain-relieving, and can treat diseases such as gastric ulcer, oral ulcer, burn and scald, skin fissure, and radiation protection; 100 micrograms/ml concentration of propolis ethanol extract 25 out of 39 kinds of bacteria and 20 out of 39 kinds of plant fungi were inhibited, which were most sensitive to Gram-positive bacteria and acid-fast bacteria. 1% - 10% propolis alcohol or ether extract is effective against common human fungi, ringworm, flocculent, rubrum, microsporum rust, microsporum gypsum, microsporum lanoides, brain-shaped Ringworm, gypsum-like ringworm, trichophyton, and purple ringworm all have inhibitory effects. It has good killing effect on cucumber mosaic virus, tobacco spot virus, tobacco necrosis virus and type A influenza virus. It can inhibit the reproduction of herpes virus and significantly reduce the infection of vaccinia virus; as early as the 1950s, propolis ointment was used abroad to successfully treat oral diseases such as recurrent aphtha, oral erosions, and ulcers. The rich and unique biologically active substances contained in propolis make it have various functions such as antibacterial, anti-inflammatory, antipruritic, anti-oxidant, immune-enhancing, hypoglycemic, hypolipidemic, anti-tumor, etc. It has a wide range of medical and health effects on the human body .
所述的桉叶油,又称白千层脑、桉树脑,是一种无色油状液体,在桉树油、玉树油、樟脑油、月桂叶油(外文名bay oil)等物质中提取而来。桉叶油为无色或微黄色液体。呈特有清凉尖刺桉叶香气并带几分樟脑气味,带些药气,有辣口清凉感,香气强烈而不持久,有一定防霉及杀菌防腐作用。 The eucalyptus oil, also known as melaleuca, eucalyptol, is a colorless oily liquid extracted from eucalyptus oil, eucalyptus oil, camphor oil, bay leaf oil (foreign name bay oil) and other substances . Eucalyptus oil is a colorless or slightly yellow liquid. It has a unique and cool aroma of thorny eucalyptus leaves with a bit of camphor smell, with some medicinal smell, it has a spicy and refreshing feeling, the aroma is strong but not long-lasting, and it has certain anti-mildew, bactericidal and antiseptic effects.
与现有技术相比,本发明的有益效果是:Compared with prior art, the beneficial effect of the present invention is:
1、本发明将肉桂油添加到口香糖中,肉桂油具有天然驱虫杀虫、杀霉菌的功效,又不会污染食物;肉桂油对常见细菌(大肠杆菌、沙门氏菌、枯草芽孢杆菌、苏云金杆菌等),酵母菌(啤酒酵母、面包酵母等)、霉菌(黑曲霉、米曲霉、黄曲霉、青霉、木霉、毛霉、根霉等)均具有很强的抑制作用,将肉桂油添加到口香糖中,具有杀灭皮肤和口腔中有害病菌的作用。加入薄荷油不仅能起到抗菌作用还能有效的综合中药成分的中药味,使中药味减淡,改善口香糖的气味,使得口香糖具有一种淡淡的薄荷清香,起到清新口气的作用;加入蜂胶能使口香糖的抗菌、清洁作用得到增强,而且蜂胶对口腔疾病有很好的治疗作用。 1. In the present invention, cinnamon oil is added to the chewing gum. The cinnamon oil has the effect of natural deworming and killing fungi, and will not pollute food; the cinnamon oil is effective against common bacteria (E. ), yeasts (brewer's yeast, baker's yeast, etc.), molds (Aspergillus niger, Aspergillus oryzae, Aspergillus flavus, Penicillium, Trichoderma, Mucor, Rhizopus, etc.) have a strong inhibitory effect, adding cinnamon oil to In chewing gum, it has the effect of killing harmful bacteria in the skin and mouth. Adding peppermint oil can not only play an antibacterial role but also effectively integrate the traditional Chinese medicine flavor of traditional Chinese medicine ingredients, so that the taste of traditional Chinese medicine can be lightened, and the smell of chewing gum can be improved, so that the chewing gum has a light mint fragrance, which can freshen the breath; adding propolis It can enhance the antibacterial and cleaning effects of chewing gum, and propolis has a good therapeutic effect on oral diseases.
2、本发明采用的中药成分综合了锦灯笼,青黛,细辛,红天葵,甘草和五倍子这几种中药药材的药效成分,清热解毒,抗菌消炎,本发明制得的口香糖能起到清洁口腔、抑制口腔有害细菌、保护牙齿、防治蛀牙的作用,极大的的提高了口腔保健的作用,对口腔疾病如牙齿肿痛、牙龈炎等起到很好的防治作用,并能更好的控制口臭和斑块的形成,对牙齿病症具有较显著的防治功效,并且中药味比较淡,对蛀牙的防治效果好。 2, the Chinese medicinal composition that the present invention adopts has synthesized the medicinal effect component of brocade lantern, Qingdai, asarum, red geranium, licorice and Chinese gall. Cleans the mouth, inhibits harmful bacteria in the mouth, protects teeth, and prevents tooth decay. It can control the formation of bad breath and plaque, and has a more significant preventive effect on dental diseases, and the taste of traditional Chinese medicine is relatively light, so it has a good effect on the prevention and treatment of tooth decay.
3、本发明采用的甜味剂为木糖醇、异麦芽糖醇,不使用砂糖,木糖醇甜度与蔗糖相当,糖醇的防龋齿特性在所有的甜味剂中效果最好,木糖醇不能被口腔中产生龋齿的细菌发酵利用,抑制链球菌生长及酸的产生;在咀嚼木糖醇时,能促进唾液分泌,唾液多了既可以冲洗口腔、牙齿中的细菌,也可以增大唾液和龋齿斑点处碱性氨基酸及氨浓度,同时减缓口腔内PH值下降,伤害牙齿的酸性物质被中和稀释,抑制了细菌在牙齿表面的吸附,从而减少了牙齿的酸蚀,防止龋齿和减少牙斑的产生,巩固牙齿。异麦芽糖醇甜度为蔗糖的42%,甜味纯正,非致龋齿性,口腔内的变形链球菌不能分解利用,不产生酸和葡聚糖,不会造成蛀牙,特别适合儿童食用。本发明采用木糖醇、异麦芽糖醇作为甜味剂具有保护牙齿、防治蛀牙的作用。 3, the sweetener that the present invention adopts is xylitol, isomalt, does not use granulated sugar, and the sweetness of xylitol is equivalent to sucrose, and the anti-caries characteristic of sugar alcohol is the best in all sweeteners, and xylose Alcohol cannot be fermented and utilized by bacteria that produce dental caries in the oral cavity, and inhibits the growth of streptococci and acid production; when chewing xylitol, it can promote saliva secretion, and more saliva can not only rinse the bacteria in the mouth and teeth, but also increase The concentration of basic amino acids and ammonia in saliva and dental caries spots, and at the same time slow down the drop of pH value in the mouth, the acidic substances that damage teeth are neutralized and diluted, inhibiting the adsorption of bacteria on the surface of teeth, thereby reducing the acid erosion of teeth, preventing dental caries and Reduces plaque buildup and strengthens teeth. The sweetness of isomalt is 42% of that of sucrose. It has a pure sweet taste and is non-cariogenic. Streptococcus mutans in the oral cavity cannot be decomposed and utilized. It does not produce acid and glucan and does not cause tooth decay. It is especially suitable for children. The present invention uses xylitol and isomalt as sweeteners to protect teeth and prevent tooth decay.
具体实施方式 Detailed ways
实施例1Example 1
一种防蛀牙口香糖,其特征在于,它是由以下重量份数的原料制成的: An anti-cavity chewing gum is characterized in that it is made of the following raw materials in parts by weight:
肉桂油0.5份;薄荷油 0.3份;桉叶油0.1份;木糖醇 3份;异麦芽糖醇20份;蜂胶0.1份;滑石粉5份;甘油4份;口香糖胶基40份; 0.5 parts of cinnamon oil; 0.3 parts of peppermint oil; 0.1 parts of eucalyptus oil; 3 parts of xylitol; 20 parts of isomalt; 0.1 parts of propolis; 5 parts of talcum powder; 4 parts of glycerin;
上述的防蛀牙口香糖,还进一步加入中药成分,其重量份数为总量的 2份; The above-mentioned anti-cavity chewing gum is further added with traditional Chinese medicine ingredients, and its parts by weight are 2 parts of the total amount;
上述的中药成分包括以下重量份数的组分:锦灯笼10份,青黛10份,细辛12份,红天葵2份,甘草4份,五倍子3份; The above-mentioned traditional Chinese medicine ingredients include the following components in parts by weight: 10 parts of brocade lanterns, 10 parts of Qingdai, 12 parts of asarum, 2 parts of red tiankui, 4 parts of licorice, and 3 parts of gallnut;
所述的蜂胶是粉碎成150~200目的蜂胶粉末。 The propolis is crushed into 150-200 mesh propolis powder.
所述的防蛀牙口香糖的制备方法步骤如下: The preparation method step of described anti-cavity chewing gum is as follows:
(1)用粉碎机分别将中药成分中的各个组分粉碎成60目,然后按重量份数取已粉碎的各个组分充分混合均匀,得到混合物,往混合物中加入醇浓度为70%乙醇,乙醇的加入量为混合物体积的2~3倍,在70℃下回流6小时,过滤,得到回流液; (1) Use a pulverizer to pulverize each component of the traditional Chinese medicine into 60 meshes, then take the pulverized components by weight and mix them well to obtain a mixture, and add ethanol with an alcohol concentration of 70% to the mixture, The amount of ethanol added is 2 to 3 times the volume of the mixture, reflux at 70°C for 6 hours, and filter to obtain the reflux liquid;
(2)将回流液进行减压蒸馏,去除乙醇,获得固状物体,将固状物体进行干燥然后粉碎成150~200目粉末,得到用于制备防蛀牙口香糖的中药成分; (2) Distill the reflux liquid under reduced pressure to remove ethanol to obtain a solid object, dry the solid object and then pulverize it into 150-200 mesh powder to obtain the traditional Chinese medicine ingredients used for preparing anti-cavity chewing gum;
(3)将重量份数的口香糖胶基在70℃下加热2小时,然后按配比加入重量份数的中药成分、肉桂油、薄荷油 、桉叶油、木糖醇、异麦芽糖醇、蜂胶、滑石粉和甘油,充分混合,搅拌均匀,得到混合物; (3) Heat the chewing gum base in parts by weight at 70°C for 2 hours, and then add parts by weight of traditional Chinese medicine ingredients, cinnamon oil, peppermint oil, eucalyptus oil, xylitol, isomalt, propolis, Talcum powder and glycerin, mix well, and stir well to get a mixture;
(4)将得到的混合物挤压成块、降温至常温,然后进行压片、分切,包装,即可得到防蛀牙口香糖。 (4) Extrude the obtained mixture into blocks, cool down to normal temperature, and then perform tableting, cutting, and packaging to obtain anti-cavity chewing gum.
实施例2Example 2
一种防蛀牙口香糖,其特征在于,它是由以下重量份数的原料制成的: An anti-cavity chewing gum is characterized in that it is made of the following raw materials in parts by weight:
肉桂油1份;薄荷油0.5份;桉叶油0.2份;木糖醇 5份;异麦芽糖醇24份;蜂胶0.2份;滑石粉7份;甘油5份;口香糖胶基60份; 1 part of cinnamon oil; 0.5 parts of peppermint oil; 0.2 parts of eucalyptus oil; 5 parts of xylitol; 24 parts of isomalt; 0.2 parts of propolis; 7 parts of talcum powder; 5 parts of glycerin; 60 parts of gum base;
上述的防蛀牙口香糖,还进一步加入中药成分,其重量份数为总量的 2.5份; The above-mentioned anti-cavity chewing gum is further added with traditional Chinese medicine ingredients, and its parts by weight are 2.5 parts of the total amount;
所述的中药成分包括以下重量份数的组分:锦灯笼13份,青黛12份,细辛14份,红天葵3份,甘草5份,五倍子4份; The traditional Chinese medicine ingredients include the following components in parts by weight: 13 parts of brocade lanterns, 12 parts of Qingdai, 14 parts of asarum, 3 parts of red tiankui, 5 parts of licorice, and 4 parts of gallnut;
所述的蜂胶是粉碎成150~200目的蜂胶粉末; The propolis is crushed into 150-200 mesh propolis powder;
所述的防蛀牙口香糖的制备方法步骤如下: The preparation method step of described anti-cavity chewing gum is as follows:
(1)用粉碎机分别将中药成分中的各个组分粉碎成70目,然后按重量份数取已粉碎的各个组分充分混合均匀,得到混合物,往混合物中加入醇浓度为70%~90%乙醇,乙醇的加入量为混合物体积的2~3倍,在75℃下回流5小时,过滤,得到回流液; (1) Use a pulverizer to pulverize each component of the traditional Chinese medicine into 70 meshes, and then take the pulverized components by weight and mix them well to obtain a mixture. Add alcohol concentration of 70% to 90% to the mixture. % ethanol, the amount of ethanol added is 2 to 3 times the volume of the mixture, reflux at 75°C for 5 hours, and filter to obtain the reflux liquid;
(2)将回流液进行减压蒸馏,去除乙醇,获得固状物体,将固状物体进行干燥然后粉碎成150~200目粉末,得到用于制备防蛀牙口香糖的中药成分; (2) Distill the reflux liquid under reduced pressure to remove ethanol to obtain a solid object, dry the solid object and then pulverize it into 150-200 mesh powder to obtain the traditional Chinese medicine ingredients used for preparing anti-cavity chewing gum;
(3)将重量份数的口香糖胶基在75℃下加热1.7小时,然后按配比加入重量份数的中药成分、肉桂油、薄荷油 、桉叶油、木糖醇、异麦芽糖醇、蜂胶、滑石粉和甘油,充分混合,搅拌均匀,得到混合物; (3) Heat the chewing gum base in parts by weight at 75°C for 1.7 hours, then add parts by weight of traditional Chinese medicine ingredients, cinnamon oil, peppermint oil, eucalyptus oil, xylitol, isomalt, propolis, Talcum powder and glycerin, mix well, and stir well to get a mixture;
(4)将得到的混合物挤压成块、降温至常温,然后进行压片、分切,包装,即可得到防蛀牙口香糖。 (4) Extrude the obtained mixture into blocks, cool down to normal temperature, and then perform tableting, cutting, and packaging to obtain anti-cavity chewing gum.
实施例3Example 3
一种防蛀牙口香糖,其特征在于,它是由以下重量份数的原料制成的: An anti-cavity chewing gum is characterized in that it is made of the following raw materials in parts by weight:
肉桂油1.5份;薄荷油0.7份;桉叶油0.4份;木糖醇 7份;异麦芽糖醇27份;蜂胶0.4份;滑石粉8份;甘油7份;口香糖胶基75份; 1.5 parts of cinnamon oil; 0.7 parts of peppermint oil; 0.4 parts of eucalyptus oil; 7 parts of xylitol; 27 parts of isomalt; 0.4 parts of propolis; 8 parts of talcum powder; 7 parts of glycerin; 75 parts of gum base;
上述的防蛀牙口香糖,还进一步加入中药成分,其重量份数为总量的3份; The above-mentioned anti-cavity chewing gum is further added with traditional Chinese medicine ingredients, the parts by weight of which are 3 parts of the total amount;
所述的中药成分包括以下重量份数的组分:锦灯笼15份,青黛13份,细辛16份,红天葵4份,甘草7份,五倍子4份; The traditional Chinese medicine ingredients include the following components in parts by weight: 15 parts of brocade lanterns, 13 parts of Qingdai, 16 parts of Asarum, 4 parts of red tiankui, 7 parts of licorice, and 4 parts of gallnut;
所述的蜂胶是粉碎成150~200目的蜂胶粉末; The propolis is crushed into 150-200 mesh propolis powder;
所述的防蛀牙口香糖的制备方法步骤如下: The preparation method step of described anti-cavity chewing gum is as follows:
(1)用粉碎机分别将中药成分中的各个组分粉碎成80目,然后按重量份数取已粉碎的各个组分充分混合均匀,得到混合物,往混合物中加入醇浓度为70%~90%乙醇,乙醇的加入量为混合物体积的2~3倍,在85℃下回流4.5小时,过滤,得到回流液; (1) Use a pulverizer to pulverize each component of the traditional Chinese medicine into 80 meshes, and then take the pulverized components by weight and mix them well to obtain a mixture. Add alcohol concentration of 70% to 90% to the mixture. % ethanol, the amount of ethanol added is 2 to 3 times the volume of the mixture, reflux at 85°C for 4.5 hours, and filter to obtain the reflux liquid;
(2)将回流液进行减压蒸馏,去除乙醇,获得固状物体,将固状物体进行干燥然后粉碎成150~200目粉末,得到用于制备防蛀牙口香糖的中药成分; (2) Distill the reflux liquid under reduced pressure to remove ethanol to obtain a solid object, dry the solid object and then pulverize it into 150-200 mesh powder to obtain the traditional Chinese medicine ingredients used for preparing anti-cavity chewing gum;
(3)将重量份数的口香糖胶基在80℃下加热1.5小时,然后按配比加入重量份数的中药成分、肉桂油、薄荷油 、桉叶油、木糖醇、异麦芽糖醇、蜂胶、滑石粉和甘油,充分混合,搅拌均匀,得到混合物; (3) Heat the chewing gum base in parts by weight at 80°C for 1.5 hours, and then add parts by weight of traditional Chinese medicine ingredients, cinnamon oil, peppermint oil, eucalyptus oil, xylitol, isomalt, propolis, Talcum powder and glycerin, mix well, and stir well to get a mixture;
(4)将得到的混合物挤压成块、降温至常温,然后进行压片、分切,包装,即可得到防蛀牙口香糖。 (4) Extrude the obtained mixture into blocks, cool down to normal temperature, and then perform tableting, cutting, and packaging to obtain anti-cavity chewing gum.
实施例4Example 4
一种防蛀牙口香糖,其特征在于,它是由以下重量份数的原料制成的: An anti-cavity chewing gum is characterized in that it is made of the following raw materials in parts by weight:
肉桂油2份;薄荷油 1份;桉叶油0.5份;木糖醇10份;异麦芽糖醇30份;蜂胶0.5份;滑石粉10份;甘油8份;口香糖胶基90份; 2 parts of cinnamon oil; 1 part of peppermint oil; 0.5 parts of eucalyptus oil; 10 parts of xylitol; 30 parts of isomalt; 0.5 parts of propolis; 10 parts of talcum powder; 8 parts of glycerin; 90 parts of chewing gum base;
上述的防蛀牙口香糖,还进一步加入中药成分,其重量份数为总量的3份; The above-mentioned anti-cavity chewing gum is further added with traditional Chinese medicine ingredients, the parts by weight of which are 3 parts of the total amount;
所述的中药成分包括以下重量份数的组分:锦灯笼17份,青黛15份,细辛18份,红天葵5份,甘草8份,五倍子5份; The traditional Chinese medicine ingredients include the following components in parts by weight: 17 parts of brocade lanterns, 15 parts of Qingdai, 18 parts of asarum, 5 parts of red tiankui, 8 parts of licorice, and 5 parts of gallnut;
所述的蜂胶是粉碎成150~200目的蜂胶粉末; The propolis is crushed into 150-200 mesh propolis powder;
所述的防蛀牙口香糖的制备方法步骤如下: The steps of the preparation method of the anti-cavity chewing gum are as follows:
(1)用粉碎机分别将中药成分中的各个组分粉碎成90目,然后按重量份数取已粉碎的各个组分充分混合均匀,得到混合物,往混合物中加入醇浓度为70%~90%乙醇,乙醇的加入量为混合物体积的2~3倍,在90℃下回流4小时,过滤,得到回流液; (1) Use a pulverizer to pulverize each component of the traditional Chinese medicine into 90 meshes, and then take the pulverized components by weight and mix them well to obtain a mixture. Add alcohol concentration of 70% to 90% to the mixture. % ethanol, the amount of ethanol added is 2 to 3 times the volume of the mixture, reflux at 90°C for 4 hours, and filter to obtain the reflux liquid;
(2)将回流液进行减压蒸馏,去除乙醇,获得固状物体,将固状物体进行干燥然后粉碎成150~200目粉末,得到用于制备防蛀牙口香糖的中药成分; (2) Distill the reflux liquid under reduced pressure to remove ethanol to obtain a solid object, dry the solid object and then pulverize it into 150-200 mesh powder to obtain the traditional Chinese medicine ingredients used for preparing anti-cavity chewing gum;
(3)将重量份数的口香糖胶基在85℃下加热1小时,然后按配比加入重量份数的中药成分、肉桂油、薄荷油 、桉叶油、木糖醇、异麦芽糖醇、蜂胶、滑石粉和甘油,充分混合,搅拌均匀,得到混合物; (3) Heat the chewing gum base in parts by weight at 85°C for 1 hour, and then add parts by weight of traditional Chinese medicine ingredients, cinnamon oil, peppermint oil, eucalyptus oil, xylitol, isomalt, propolis, Talcum powder and glycerin, mix well, and stir well to get a mixture;
(4)将得到的混合物挤压成块、降温至常温,然后进行压片、分切,包装,即可得到防蛀牙口香糖。 (4) Extrude the obtained mixture into blocks, cool down to normal temperature, and then perform tableting, cutting, and packaging to obtain anti-cavity chewing gum.
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| CN109010822A (en) * | 2018-09-10 | 2018-12-18 | 广州汇高生物科技有限公司 | A kind of medical chewing gum and preparation method thereof |
| WO2020101601A3 (en) * | 2018-11-15 | 2021-01-14 | Palabiyik Ibrahim | Method for producing chewing gum using propolis in solid resin form |
| CN114698721A (en) * | 2022-03-25 | 2022-07-05 | 南阳市瑞佳食品有限公司 | Tooth-protecting and tooth-strengthening lollipop and preparation method thereof |
| CN115624506A (en) * | 2021-07-16 | 2023-01-20 | 好维股份有限公司 | Oral care product containing inulin and application thereof |
| EP4175653A4 (en) * | 2020-11-13 | 2024-05-15 | Shiban Canada Inc. | COMPOSITIONS COMPRISING NATURAL EXTRACTS TO STIMULATE THE IMMUNE RESPONSE |
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| CN102885899A (en) * | 2011-07-21 | 2013-01-23 | 天津太平洋制药有限公司 | Chinese medicinal canker sore powder |
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| CN1317328A (en) * | 2000-04-13 | 2001-10-17 | 崔北双 | Medicine for stomatitis |
| CN1610505A (en) * | 2001-12-27 | 2005-04-27 | 朴源澈 | Chewing bar and producing procedure thereof |
| CN101444567A (en) * | 2007-11-26 | 2009-06-03 | 天津市金圭谷木糖醇有限公司 | Double-layer traditional Chinese medicine patch for treating oral ulcer and preparation method thereof |
| CN102106443A (en) * | 2010-12-20 | 2011-06-29 | 王建军 | Medicinal chewing gum and preparation method thereof |
| CN102885899A (en) * | 2011-07-21 | 2013-01-23 | 天津太平洋制药有限公司 | Chinese medicinal canker sore powder |
| CN102579655A (en) * | 2012-03-27 | 2012-07-18 | 李文汉 | Externally applied traditional Chinese medicine preparation for treating oral ulcer |
| CN104431048A (en) * | 2013-09-25 | 2015-03-25 | 张勤红 | Asarum and liquorice tea |
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| CN105168340A (en) * | 2015-09-25 | 2015-12-23 | 重庆市极鼎食品有限责任公司 | Preparation method of traditional Chinese medicine composition for candies |
| CN109010822A (en) * | 2018-09-10 | 2018-12-18 | 广州汇高生物科技有限公司 | A kind of medical chewing gum and preparation method thereof |
| WO2020101601A3 (en) * | 2018-11-15 | 2021-01-14 | Palabiyik Ibrahim | Method for producing chewing gum using propolis in solid resin form |
| EP4175653A4 (en) * | 2020-11-13 | 2024-05-15 | Shiban Canada Inc. | COMPOSITIONS COMPRISING NATURAL EXTRACTS TO STIMULATE THE IMMUNE RESPONSE |
| CN115624506A (en) * | 2021-07-16 | 2023-01-20 | 好维股份有限公司 | Oral care product containing inulin and application thereof |
| CN114698721A (en) * | 2022-03-25 | 2022-07-05 | 南阳市瑞佳食品有限公司 | Tooth-protecting and tooth-strengthening lollipop and preparation method thereof |
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Application publication date: 20150923 |