CN104825203A - Cerebral aneurysm embolization therapeutic device and using method thereof - Google Patents
Cerebral aneurysm embolization therapeutic device and using method thereof Download PDFInfo
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- CN104825203A CN104825203A CN201510174439.0A CN201510174439A CN104825203A CN 104825203 A CN104825203 A CN 104825203A CN 201510174439 A CN201510174439 A CN 201510174439A CN 104825203 A CN104825203 A CN 104825203A
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- rhombus
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- silk thread
- cerebral aneurysm
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- 201000008450 Intracranial aneurysm Diseases 0.000 title claims abstract description 34
- 230000010102 embolization Effects 0.000 title claims abstract description 34
- 238000000034 method Methods 0.000 title claims abstract description 16
- 230000001225 therapeutic effect Effects 0.000 title abstract 3
- 230000000694 effects Effects 0.000 claims abstract description 7
- 206010002329 Aneurysm Diseases 0.000 claims description 25
- 229910003460 diamond Inorganic materials 0.000 claims description 15
- 239000010432 diamond Substances 0.000 claims description 15
- 238000001523 electrospinning Methods 0.000 claims description 7
- 238000003032 molecular docking Methods 0.000 claims description 6
- 238000000280 densification Methods 0.000 claims description 4
- 238000005868 electrolysis reaction Methods 0.000 claims description 4
- 239000000853 adhesive Substances 0.000 claims description 3
- 230000001070 adhesive effect Effects 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 238000004804 winding Methods 0.000 claims description 3
- 241001146209 Curio rowleyanus Species 0.000 abstract 2
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 abstract 1
- 229910001000 nickel titanium Inorganic materials 0.000 abstract 1
- 230000000306 recurrent effect Effects 0.000 abstract 1
- 229910001285 shape-memory alloy Inorganic materials 0.000 abstract 1
- 208000005189 Embolism Diseases 0.000 description 3
- 208000001435 Thromboembolism Diseases 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 230000007334 memory performance Effects 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009432 framing Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12031—Type of occlusion complete occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12163—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a string of elements connected to each other
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Surgical Instruments (AREA)
Abstract
Provided in the invention is a cerebral aneurysm embolization therapeutic device and a using method thereof. The invention discloses a suture-contained cerebral aneurysm embolization therapeutic device and a using method thereof. The device comprises a conveying guide wire, a sheath pipe, a skeleton suture, and a PU nanometer electrospining net. The skeleton suture is in a rhombus shape; a nickel-titanium memory alloy wire is connected in a head-to-end mode to form an annular shape and then is drawn to prefabricate and form the rhombus-shaped skeleton suture. A PU nanometer electrospining wire is attached to the surface of the rhombus-shaped skeleton suture; the PU nanometer electrospining wire is interlaced in the rhombus-shaped skeleton suture to form the PU nanometer electrospining net. The skeleton suture is arranged in a shape like a string of beads based on connecting points of the rhombuses; the connecting points of the rhombus-shaped skeleton suture are flexible bonding ones; and the rhombus-shaped skeleton suture in a shape like a string of beads circles into a spiral shape to fill the cerebral aneurysm automatically according to the cerebral aneurysm space structure. According to the invention, the effective embolization area and embolization effect are increased; and the operation difficulty, the treatment cost, and the cerebral aneurysm recurrent risk are reduced. The device is sent into the cerebral aneurysm cavity by a micro pipe, thereby achieving a cerebral aneurysm enclosing objective.
Description
Technical field
The present invention relates to embolotherapy apparatus in cerebral aneurysm, relate to embolotherapy apparatus and using method thereof in a kind of cerebral aneurysm specifically.
Background technology
In cerebral aneurysm, embolotherapy apparatus has Detachable balloons and detachable coil.The direction need complying with blood flow when Detachable balloons uses could arrive in aneurysm, clinical handling difference; In addition, can take off ball sacculus be difficult to adapt to aneurysmal irregularly shaped, likely burst aneurysm, cause aneurysm rupture; Finally, sacculus likely dissociates out after freeing and the risk of dystopy thromboembolism occurs, therefore the existing clinical less thromboembolism for cerebral aneurysm.
Detachable coil conventional clinically, all being spiraled to be wound around with single diameter type, two diameter type (2-D) or three dimensional type (3-D) skeleton by a tinsel with memory performance forms.The shortcoming of this configuration is, first selects a turn matched with aneurysm diameter to clog during use, but often leaves space after the filling of single turn, and follow-up palpus constantly clogs turn to reach the object of filling completely.In process of clinical application, larger aneurysm will reach complete thromboembolism often need use multiple turn, and medical expense is high, and operation technique difficulty increases, and aneurysm rupture risk also increases; In addition, if turn filling not exclusively likely causes aneurysm risk of recurrence.
Summary of the invention
For deficiency of the prior art, the technical problem to be solved in the present invention there are provided embolization device and using method thereof in a kind of band silk cerebral aneurysm.
For solving the problems of the technologies described above, the present invention is realized by following scheme: embolization device in a kind of band silk cerebral aneurysm, this apparatus comprises delivery guidewire, sheath pipe, skeleton silk thread, PU nanometer electrospinning silk screen, described skeleton silk thread assumes diamond in shape, the skeleton silk thread of diamond shaped is after circularizing by Ultimum Ti silk is from beginning to end, tractive is prefabricated into rhombus and is made again, the skeleton wire surface of diamond shaped is attached with PU nanometer Electrospun, PU nanometer Electrospun interweaves and connects to net in the middle of the skeleton silk thread of rhombus, form PU nanometer electrospinning silk screen, described skeleton silk thread is beading by the junction point arrangement between rhombus, junction point between rhombus skeleton silk thread is flexible adhesive point, in beading rhombus skeleton silk thread according to cerebral aneurysm space structure, automatically the curl that spirals filling aneurysm.
Further, four angles of the skeleton silk thread of diamond shaped are circular.
Further, the diameter that the skeleton silk thread of described rhombus opens is between 1.5 ~ 10mm, and its external diameter width forming rhombus is between 2 ~ 4mm.
Further, after the curl that automatically spirals in beading rhombus skeleton silk thread, the screw diameter of its helical configuration between 1 ~ 20mm, pitch is between 0.4 ~ 0.8mm.
Further, described sheath pipe lumen diameter is identical with the neuro microcatheter internal diameter of 1.9F, head end and the seamless docking of microtubular tail end.
With a using method for embolization device in a cerebral aneurysm, the method comprises the following steps:
1) the configuration automatic winding that, spiraled in the shape of a spiral by the beading rhombus skeleton silk thread of more than three or three is integrally connected the skeleton of composition apparatus;
2), the head end of beading rhombus skeleton silk thread of more than three or three is connected by the de-point of electrolysis with the conductive filament head of delivery guidewire, is placed in sheath pipe tube chamber by the stretching one-tenth of the beading rhombus skeleton silk thread single metal wire side by side of more than three or three;
3), sheath pipe lumen diameter is identical with the neuro microcatheter internal diameter of 1.9F, head end and the seamless docking of microtubular tail end, so as beading rhombus skeleton silk thread linearly type enter in microtubular;
4), by pushing delivery guidewire sent in aneurysm by beading rhombus skeleton silk thread, after having discharged, rhombus skeleton silk thread opens, automatically tortuous in aneurysm in the shape of a spiral by soft bounding point;
5), the tortuous in the shape of a spiral skeleton silk thread in aneurysm closes Aneurysmformation densification filling, adds effective Embolization area and the effect of embolization of embolization device in band silk cerebral aneurysm.
Relative to prior art, the invention has the beneficial effects as follows: the present invention is the turn that beading rhombus framework type bone spiral spirals by the tinsel with memory performance of more than three or three, according to aneurysmal space structure, select sizeable turn, by curl filling aneurysm of automatically spiraling after freeing, not only add effective Embolization area and effect of embolization, also reduce operation easier, medical expense and aneurysm risk of recurrence.Embolization device of the present invention is conveyed in aneurysm cavity through microtubular, reaches closed aneurysmal object.
Accompanying drawing explanation
Fig. 1 is beading rhombus framing structure schematic diagram of the present invention.
Fig. 2 is that beading rhombus skeleton spiral of the present invention spirals structural representation.
Labelling in accompanying drawing: delivery guidewire 1; The de-point 2 of electrolysis; Sheath pipe 3; Rhombus skeleton silk thread 4; Soft bounding point 5; PU nanometer electrospinning silk screen 6; Annular corner 7.
Detailed description of the invention
Below in conjunction with drawings and Examples, technical scheme of the present invention is explained in detail.
Please refer to accompanying drawing 1 ~ 2, embolization device in one band silk cerebral aneurysm of the present invention, this apparatus comprises delivery guidewire 1, sheath pipe 3, skeleton silk thread 4, PU nanometer electrospinning silk screen 6, described skeleton silk thread 4 assumes diamond in shape, the skeleton silk thread 4 of diamond shaped is after circularizing by Ultimum Ti silk is from beginning to end, tractive is prefabricated into rhombus and is made again, skeleton silk thread 4 surface attachment of diamond shaped has PU nanometer Electrospun, PU nanometer Electrospun interweaves and connects to net in the middle of the skeleton silk thread 4 of rhombus, form PU nanometer electrospinning silk screen 6, described skeleton silk thread 4 is beading by the junction point arrangement between rhombus, junction point between rhombus skeleton silk thread 4 is flexible adhesive point, in beading rhombus skeleton silk thread according to cerebral aneurysm space structure, automatically the curl that spirals filling aneurysm, four angles of the skeleton silk thread 4 of diamond shaped are circular.The diameter that the skeleton silk thread 4 of described rhombus opens is between 1.5 ~ 10mm, its external diameter width forming rhombus is between 2 ~ 4mm, automatically spiral after curl in beading rhombus skeleton silk thread, the screw diameter of its helical configuration between 1 ~ 20mm, pitch is between 0.4 ~ 0.8mm, described sheath pipe 3 lumen diameter is identical with the neuro microcatheter internal diameter of 1.9F, head end and the seamless docking of microtubular tail end.In order to realize the densification filling of cerebral aneurysm, embolization device in band silk cerebral aneurysm of the present invention, the every root skeleton silk thread forming this apparatus assumes diamond in shape, the skeleton silk thread assumed diamond in shape circularizes the prefabricated diamondwise of rear tractive by Ultimum Ti silk is from beginning to end, the diameter that prefabricated rhombus skeleton silk thread 4 opens is between 1.5 ~ 10mm, this mainly sees aneurysmal size, applicable skeleton silk thread 4 is used with actual artery tumor size, the skeleton silk thread assumed diamond in shape can be drawn as linearity through microtubular conveying release, four angles of rhombus skeleton silk thread 4 are designed to annular, form annular corner 7, this annular design can effectively reduce in turn dispose procedure aneurysmal damage, rhombus skeleton silk thread 4 surface is attached PU nanometer Electrospun, PU nanometer Electrospun interweaves and connects to net in the middle of rhombus skeleton silk thread, add effective Embolization area and the effect of embolization of this type of apparatus, rhombus skeleton silk thread 4 is by the junction point arrangement between rhombus in beading, and the junction point between rhombus skeleton silk thread 4 is soft bounding point, adds submissive performance and the space structure adaptability of this type of apparatus, in beading rhombus skeleton silk thread according to cerebral aneurysm space structure, automatically the curl that spirals filling aneurysm, the screw diameter 1 ~ 20mm of helical configuration, pitch 0.4 ~ 0.8mm, to adapt to the aneurysm needs of different inner diameters, reach fine and close filling and close aneurysmal object.
Please refer to accompanying drawing 2, a kind of using method with embolization device in a cerebral aneurysm, the method comprises the following steps:
1, the configuration automatic winding that spiraled in the shape of a spiral by the beading rhombus skeleton silk thread 4 of more than three or three is integrally connected the skeleton of composition apparatus;
2, the head end of beading rhombus skeleton silk thread 4 of more than three or three is connected by the de-point 2 of electrolysis with the conductive filament head of delivery guidewire 1, is placed in sheath pipe 3 tube chamber by the beading rhombus skeleton stretching one-tenth of silk thread 4 single metal wire side by side of more than three or three;
3, sheath pipe 3 lumen diameter is identical with the neuro microcatheter internal diameter of 1.9F, head end and the seamless docking of microtubular tail end, so as beading rhombus skeleton silk thread linearly type enter in microtubular;
4, send in aneurysm by pushing delivery guidewire 1 by beading rhombus skeleton silk thread 4, after having discharged, rhombus skeleton silk thread 4 opens, automatically tortuous in aneurysm in the shape of a spiral by soft bounding point 5;
5, the 4 pairs of Aneurysmformation densification fillings of the tortuous in the shape of a spiral skeleton silk thread in aneurysm are closed, and add effective Embolization area and the effect of embolization of embolization device in band silk cerebral aneurysm.
Embolization device in band silk cerebral aneurysm of the present invention, adds effective Embolization area and the effect of embolization of this type of apparatus, is conveyed in aneurysm cavity through microtubular, reach closed aneurysmal object.
The foregoing is only the preferred embodiment of the present invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical field, be all in like manner included in scope of patent protection of the present invention.
Claims (6)
1. embolization device in a band silk cerebral aneurysm, it is characterized in that: this apparatus comprises delivery guidewire (1), sheath pipe (3), skeleton silk thread (4), PU nanometer electrospinning silk screen (6), described skeleton silk thread (4) assumes diamond in shape, the skeleton silk thread (4) of diamond shaped is after circularizing by Ultimum Ti silk is from beginning to end, tractive is prefabricated into rhombus and is made again, skeleton silk thread (4) surface attachment of diamond shaped has PU nanometer Electrospun, PU nanometer Electrospun interweaves and connects to net in the middle of the skeleton silk thread (4) of rhombus, form PU nanometer electrospinning silk screen (6), described skeleton silk thread (4) is beading by the junction point arrangement between rhombus, junction point between rhombus skeleton silk thread (4) is flexible adhesive point, in beading rhombus skeleton silk thread according to cerebral aneurysm space structure, automatically the curl that spirals filling aneurysm.
2. embolization device in one band silk cerebral aneurysm according to claim 1, is characterized in that: four angles of the skeleton silk thread (4) of diamond shaped are circular.
3. embolization device in one band silk cerebral aneurysm according to claim 1 and 2, is characterized in that: the diameter that the skeleton silk thread (4) of described rhombus opens is between 1.5 ~ 10mm, and its external diameter width forming rhombus is between 2 ~ 4mm.
4. embolization device in one band silk cerebral aneurysm according to claim 1, is characterized in that: after the curl that automatically spirals in beading rhombus skeleton silk thread, the screw diameter of its helical configuration between 1 ~ 20mm, pitch is between 0.4 ~ 0.8mm.
5. embolization device in one band silk cerebral aneurysm according to claim 1, is characterized in that: described sheath pipe (3) lumen diameter is identical with the neuro microcatheter internal diameter of 1.9F, head end and the seamless docking of microtubular tail end.
6., with the using method of claim 1 with embolization device in silk cerebral aneurysm, it is characterized in that, the method comprises the following steps:
1) the configuration automatic winding that, spiraled in the shape of a spiral by beading rhombus skeleton silk thread (4) of more than three or three is integrally connected the skeleton of composition apparatus;
2), the head end of beading rhombus skeleton silk thread (4) of more than three or three takes off point (2) with the conductive filament head of delivery guidewire (1) by electrolysis and is connected, and is placed in sheath pipe (3) tube chamber by beading rhombus skeleton silk thread (4) the stretching one-tenth single metal wire side by side of more than three or three;
3), sheath pipe (3) lumen diameter is identical with the neuro microcatheter internal diameter of 1.9F, head end and the seamless docking of microtubular tail end, so as beading rhombus skeleton silk thread linearly type enter in microtubular;
4), by pushing delivery guidewire (1) sent in aneurysm by beading rhombus skeleton silk thread (4), after having discharged, rhombus skeleton silk thread (4) opens, automatically tortuous in aneurysm in the shape of a spiral by soft bounding point (5);
5), the tortuous in the shape of a spiral skeleton silk thread (4) in aneurysm closes Aneurysmformation densification filling, adds effective Embolization area and the effect of embolization of embolization device in band silk cerebral aneurysm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510174439.0A CN104825203A (en) | 2015-04-14 | 2015-04-14 | Cerebral aneurysm embolization therapeutic device and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510174439.0A CN104825203A (en) | 2015-04-14 | 2015-04-14 | Cerebral aneurysm embolization therapeutic device and using method thereof |
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| Publication Number | Publication Date |
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| CN104825203A true CN104825203A (en) | 2015-08-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510174439.0A Pending CN104825203A (en) | 2015-04-14 | 2015-04-14 | Cerebral aneurysm embolization therapeutic device and using method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112206031A (en) * | 2020-11-11 | 2021-01-12 | 北京久事神康医疗科技有限公司 | Aneurysm embolization device |
| WO2022042345A1 (en) * | 2020-08-31 | 2022-03-03 | 微创神通医疗科技（上海）有限公司 | Hemangioma blocking device, hemangioma blocking treatment device and hemangioma blocking system |
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| CN200991273Y (en) * | 2006-11-21 | 2007-12-19 | 张静波 | Stepladder-shape spring ring for embolism aneurysm |
| CN101426454A (en) * | 2004-05-25 | 2009-05-06 | 切斯纳特医学技术公司 | Flexible vascular embolization device |
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| CN202724037U (en) * | 2012-08-01 | 2013-02-13 | 吕文峰 | Support and conveying system thereof for treating arterial aneurysm |
| EP2716263A1 (en) * | 2011-05-26 | 2014-04-09 | Dongguk University Industry-Academic Cooperation Foundation | Stent for the coil embolization of a cerebral aneurysm |
| CN104257412A (en) * | 2014-09-19 | 2015-01-07 | 陈旭东 | Interventional treatment instrument made from composite material and used for treating cerebral aneurysm embolism |
| CN104434353A (en) * | 2014-12-04 | 2015-03-25 | 曾延华 | Electronic detaching and etching covered stent for treatment of intracranial aneurysm and operation method thereof |
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2015
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| EP1698284A1 (en) * | 2005-03-02 | 2006-09-06 | Cordis Neurovascular, Inc. | Embolic coil with twisted wire |
| CN200991273Y (en) * | 2006-11-21 | 2007-12-19 | 张静波 | Stepladder-shape spring ring for embolism aneurysm |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022042345A1 (en) * | 2020-08-31 | 2022-03-03 | 微创神通医疗科技（上海）有限公司 | Hemangioma blocking device, hemangioma blocking treatment device and hemangioma blocking system |
| CN112206031A (en) * | 2020-11-11 | 2021-01-12 | 北京久事神康医疗科技有限公司 | Aneurysm embolization device |
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