CN1048162C - Regeneration pill for curing spinal nerve injury - Google Patents
Regeneration pill for curing spinal nerve injury Download PDFInfo
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- CN1048162C CN1048162C CN93107525A CN93107525A CN1048162C CN 1048162 C CN1048162 C CN 1048162C CN 93107525 A CN93107525 A CN 93107525A CN 93107525 A CN93107525 A CN 93107525A CN 1048162 C CN1048162 C CN 1048162C
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- China
- Prior art keywords
- processed
- semen strychni
- moschus
- myrrha
- olibanum
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 210000001032 spinal nerve Anatomy 0.000 title abstract description 7
- 230000008929 regeneration Effects 0.000 title abstract description 6
- 238000011069 regeneration method Methods 0.000 title abstract description 6
- 239000006187 pill Substances 0.000 title abstract 4
- 208000028389 Nerve injury Diseases 0.000 title abstract 2
- 230000008764 nerve damage Effects 0.000 title abstract 2
- 239000003814 drug Substances 0.000 claims abstract description 24
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 9
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 9
- 230000000472 traumatic effect Effects 0.000 claims abstract description 7
- 229940079593 drug Drugs 0.000 claims abstract description 6
- 210000000582 semen Anatomy 0.000 claims description 11
- 241000717739 Boswellia sacra Species 0.000 claims description 8
- 239000004863 Frankincense Substances 0.000 claims description 8
- 241000283956 Manis Species 0.000 claims description 8
- 241000972155 Moschus Species 0.000 claims description 8
- 241001057584 Myrrha Species 0.000 claims description 8
- 206010033799 Paralysis Diseases 0.000 claims description 8
- 239000009286 sanguis draxonis Substances 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000000843 powder Substances 0.000 claims description 5
- 239000002775 capsule Substances 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 238000005303 weighing Methods 0.000 claims 1
- 239000008280 blood Substances 0.000 abstract description 8
- 210000004369 blood Anatomy 0.000 abstract description 8
- 206010033892 Paraplegia Diseases 0.000 abstract description 7
- 230000001737 promoting effect Effects 0.000 abstract description 6
- 230000017531 blood circulation Effects 0.000 abstract description 5
- GXFZCDMWGMFGFL-KKXMJGKMSA-N (+)-Tubocurarine chloride hydrochloride Chemical compound [Cl-].[Cl-].C([C@H]1[N+](C)(C)CCC=2C=C(C(=C(OC3=CC=C(C=C3)C[C@H]3C=4C=C(C(=CC=4CC[NH+]3C)OC)O3)C=21)O)OC)C1=CC=C(O)C3=C1 GXFZCDMWGMFGFL-KKXMJGKMSA-N 0.000 abstract 1
- 241001111317 Chondrodendron tomentosum Species 0.000 abstract 1
- 235000015655 Crocus sativus Nutrition 0.000 abstract 1
- 244000124209 Crocus sativus Species 0.000 abstract 1
- 239000008709 Curare Substances 0.000 abstract 1
- 241000218671 Ephedra Species 0.000 abstract 1
- 241000283966 Pholidota <mammal> Species 0.000 abstract 1
- 235000013974 saffron Nutrition 0.000 abstract 1
- 239000004248 saffron Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 6
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 210000005036 nerve Anatomy 0.000 description 3
- 210000000278 spinal cord Anatomy 0.000 description 3
- 206010052428 Wound Diseases 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000002485 urinary effect Effects 0.000 description 2
- 206010002027 Amyotrophy Diseases 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010010254 Concussion Diseases 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 208000012661 Dyskinesia Diseases 0.000 description 1
- 206010018852 Haematoma Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 208000034693 Laceration Diseases 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- RRKTZKIUPZVBMF-IBTVXLQLSA-N brucine Chemical compound O([C@@H]1[C@H]([C@H]2C3)[C@@H]4N(C(C1)=O)C=1C=C(C(=CC=11)OC)OC)CC=C2CN2[C@@H]3[C@]41CC2 RRKTZKIUPZVBMF-IBTVXLQLSA-N 0.000 description 1
- RRKTZKIUPZVBMF-UHFFFAOYSA-N brucine Natural products C1=2C=C(OC)C(OC)=CC=2N(C(C2)=O)C3C(C4C5)C2OCC=C4CN2C5C31CC2 RRKTZKIUPZVBMF-UHFFFAOYSA-N 0.000 description 1
- 210000003164 cauda equina Anatomy 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000002153 concerted effect Effects 0.000 description 1
- 230000009514 concussion Effects 0.000 description 1
- 230000009519 contusion Effects 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 210000001951 dura mater Anatomy 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 239000009519 fu-yuan Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000002684 laminectomy Methods 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 208000020431 spinal cord injury Diseases 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000003235 vasospasmolytic effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a regeneration pill for curing spinal nerve injuries, which selects medicines according to a principle of promoting blood circulation for removing blood stasis, and is prepared from saffron, notoginseng, fried pangolin, raw ephedra, raw curare, etc. The regeneration pill used for treating a patient of traumatic paraplegia can predominantly promote the restoration and the regeneration of the function of the spinal nerves, the regeneration pill has a total effective rate of 89.9%., an effective rate of 75%, and a rate of basic life self-care of the patient is 57%.
Description
The present invention relates to a kind of medicine, particularly is the pharmaceuticals of raw material with the Chinese herbal medicine.
Vertebra exogenous injury dislocation merges spinal cord injury and causes paraplegia, is one of difficult and complicated illness in the world now.So-called traumatic paralysis is meant because of extraneous violence effect causes cervical vertebra, thoracic vertebra, lumbar vertebra fracture, dislocation, intervertebral disk hernia, and dura mater is dampened, hematoma, thereby makes spinal nerves fracture or pressurized, afunction.After the function of spinal nerves forfeiture, cause patient to produce following clinical symptoms: the following dyskinesia in paraplegia plane, anesthesia, gatism, amyotrophy then takes place in that continues, and pipe is foster bad, decubital ulcer, complication such as urinary system infection.
Treatment to this paraplegia, the doctor trained in Western medicine scholar of China and foreign countries is more with the treatment of operation laminectomy for decompression, main purpose is to make pathological changes subduction such as spinal cord due to the vertebral body displacement or cauda equina nerve contusion, laceration or concussion injury or alleviate, and its clinical cure rate (reaching life is basic takes care of oneself) is between 15-20%; Traditional Chinese medical science scholar then with acupuncture, method treatment such as massage, take medicine.Wherein, be the representative prescription with great achievement soup and Fuyuan Huoxue Tang in the Chinese medicine, its cure rate is between 5-10%.Make a general survey of the treatment of Chinese and western medicine scholar to this disease, its curative effect is unsatisfactory, thereby makes this disease become one of thorny in the world difficult disease.
The objective of the invention is to develop a kind of spinal nerves medicament, it can remove traumatic paralysis patient's slight illness, makes function major part such as the following nerve in paraplegia plane, muscle or full recovery normal, and life can take care of oneself basically.
The object of the present invention is achieved like this: with the theory of the traditional Chinese medical science " the blood stasis of blood of not living can not be dispelled, and the stasis of blood bone of can not dispelling can not connect " for instructing determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, with " blood circulation promoting and blood stasis dispelling " as the selection principle of being used as medicine, be made into prescription, reach the purpose of treatment, its basic prescription is:
A kind of Chinese medicine preparation for the treatment of traumatic paralysis, its basic comprising is: it is made up of Stigma Croci, Radix Notoginseng, Squama Manis (processed), Sanguis Draxonis, Olibanum (processed), Myrrha (processed), Semen Strychni, Herba Ephedrae, Moschus, and each component content unit is by weight counted:
Stigma Croci: 2-4;
Radix Notoginseng: 1-2;
Squama Manis (processed): 1-2;
Sanguis Draxonis: 2-4;
Olibanum (processed): 2-4;
Myrrha (processed): 2-4;
Semen Strychni: 2-3.5;
Herba Ephedrae: 0.2-0.35;
Moschus: 0.1-0.15.
The invention will be further described below with reference to embodiment.
Acting as of each component medicine: Stigma Croci, Radix Notoginseng, Sanguis Draxonis, Olibanum (processed), Myrrha (processed), energy anti-inflammatory analgetic, blood circulation promoting and blood stasis dispelling, promoting tissue regeneration by removing blood stasis, reunion of bone, clinical application effect is very good; Semen Strychni, it has closed alkaloid and brucine, has stimulating central nervous system, promotes microcirculation, vasospasmolytic effect.It is acted on spinal cord, can make impulsion between neuron, be easy to conduction, and can guide all medicines through sick institute; Herba Ephedrae energy expelling wind and removing dampness; Moschus energy promoting blood circulation and detumescence, suffering are loose and are walked to scurry, and control sore swollen toxin, traumatic injury etc.; Squama Manis (processed) energy dredging the meridian makes nerve recovery and regeneration.More than these several herbal medicines make prescription, can the principal and subordinate make a concerted effort, complement each other, altogether the effect of tool blood circulation promoting and blood stasis dispelling, reunion of bone, excited spinal cord, regenerating nerve, expelling wind and removing dampness, dredging the meridian.
When said medicine was made prescription, operation as follows: with Semen Strychni with Cortex Cinnamomi, Radix Glycyrrhizae together, in 1: 0.1-0.23: the ratio of 0.2-0.3 was weighed water logging 7-10 days, the malicious sustainability of dispelling, peeling, cut into slices dry be crushed into powder standby.Also be ground into powder (about about 100 orders) after other medicines are weighed by prescription, then with the Semen Strychni mixing the powder finished product.Take for ease of the patient, preferably make capsule again, every can be by 0.3 gram counterweight.
Three embodiment of the present invention are:
Medicine name prescription 1 dosage prescription 2 dosage prescriptions 3 dosage
Stigma Croci 2.3 4 2.7
Radix Notoginseng 1.7 1.2 2
Squama Manis (processed) 1.0 1.6 1.3
Sanguis Draxonis 2.9 4 2.7
Semen Strychni 2.8 3 3.3
Olibanum (processed) 3.1 2.8 3.6
Myrrha (processed) 4 2.5 2.7
Herba Ephedrae 0.27 0.24 0.29
Moschus 0.14 0.11 0.13
Chinese medicine preparation capsule by the present invention makes is used for orally taken for curing wound paralyses patient, and total effective rate reaches 89.9%.Obvious effective rate reaches 75%, and the basic self-care rate of living reaches 57%, some patient even recovered certain work capacity.One group of patient according to nearest clinic observation, totally 68 examples, wherein, complete paraplegia 31 examples, incomplete paraplegia 37 examples are after treatment, the recovery from illness or 23 examples that are almost recovered, more good 27 examples that account in back still can account for 12 examples after healing, more relatively poor 6 examples that account in back, these case proofs capsule of the present invention is to the limbs of paralyses patient, the recovery of muscle and fecal and urinary functions has important role really, all after wound or continuous medication treatment 4-6 month the patient of postoperative, its curative effect is very good, otherwise, recover drug withdrawal because of function is temporary transient, fail to consolidate curative effect, the function of nervous system of having recovered also may tend to disappear.The case of this pros and cons has proved that fully medicament of the present invention is to influence that spinal nerves produced.
Claims (3)
1. a Chinese medicine preparation for the treatment of traumatic paralysis is characterized in that, it is made by Stigma Croci, Radix Notoginseng, Squama Manis (processed), Sanguis Draxonis, Olibanum (processed), Myrrha (processed), Semen Strychni, Herba Ephedrae, Moschus, and each component content unit is by weight counted:
Stigma Croci: 2-4;
Radix Notoginseng: 1-2;
Squama Manis (processed): 1-2;
Sanguis Draxonis: 2-4;
Olibanum (processed): 2-4;
Myrrha (processed): 2-4;
Semen Strychni: 2-3.5;
Herba Ephedrae: 0.2-0.35;
Moschus: 0.1-0.15.
2. a manufacture method for the treatment of the Chinese medicine preparation of traumatic paralysis is characterized in that, said preparation is made by Stigma Croci, Radix Notoginseng, Squama Manis (processed), Sanguis Draxonis, Olibanum (processed), Myrrha (processed), Semen Strychni, Herba Ephedrae, Moschus, and each component content unit is by weight counted:
Stigma Croci: 2-4;
Radix Notoginseng: 1-2;
Squama Manis (processed): 1-2;
Sanguis Draxonis: 2-4;
Olibanum (processed): 2-4;
Myrrha (processed): 2-4;
Semen Strychni: 2-3.5;
Herba Ephedrae: 0.2-0.35;
Moschus: 0.1-0.15;
Above-mentioned each component medicine is weighed by ratio requirement, and with Semen Strychni with Cortex Cinnamomi, Radix Glycyrrhizae together, in 1: 0.1-0.23: the water logging of weighing of the ratio of 0.2-0.3 was steeped 7-10 days, peeling, cut into slices, dry, pulverize, other medicines also are ground into powder, mixing gets product then.
3. according to the manufacture method of the described Chinese medicine preparation of claim 2, it is characterized in that, described powder is made capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93107525A CN1048162C (en) | 1993-06-30 | 1993-06-30 | Regeneration pill for curing spinal nerve injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93107525A CN1048162C (en) | 1993-06-30 | 1993-06-30 | Regeneration pill for curing spinal nerve injury |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1102099A CN1102099A (en) | 1995-05-03 |
| CN1048162C true CN1048162C (en) | 2000-01-12 |
Family
ID=4986740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93107525A Expired - Lifetime CN1048162C (en) | 1993-06-30 | 1993-06-30 | Regeneration pill for curing spinal nerve injury |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1048162C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1630528A (en) * | 1999-08-30 | 2005-06-22 | 独立行政法人科学技术振兴机构 | Brain Cell or Nerve Cell Protector Containing Medicinal Ginseng |
| CN107281353A (en) * | 2017-08-18 | 2017-10-24 | 赵彩红 | A kind of Chinese medicine of promotion nerve regneration |
-
1993
- 1993-06-30 CN CN93107525A patent/CN1048162C/en not_active Expired - Lifetime
Non-Patent Citations (5)
| Title |
|---|
| 《中医药信息》1986年4月1日 1986.4.30 余锡明,马钱子在脊柱损伤疾患中的应用 * |
| 《中西医结合杂志》1991-11-1 1991.1.30 黄中湖/中西医结合治疗外伤性不全截瘫5例 * |
| 《江西中医药》1990,21(6) 1990.6.30 熊这 熊赛君/膈下通瘰痃汤治疗外伤性截瘫尿潴留15例 * |
| 《河南中医》1986,(2) 1986.2.28 吴一渊/毒药猛剂善起治疗 * |
| 《河南中医》1986,(2) 1986.2.28 吴一渊/毒药猛剂善起治疗;《江西中医药》1990,21(6) 1990.6.30 熊这 熊赛君/膈下通瘰痃汤治疗外伤性截瘫尿潴留15例;《中西医结合杂志》1991-11-1 1991.1.30 黄中湖/中西医结合治疗外伤性不全截瘫5例;《中医药信息》1986年4月1日 1986.4.30 余锡明,马钱子在脊柱损伤疾患中的应用 * |
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| Publication number | Publication date |
|---|---|
| CN1102099A (en) | 1995-05-03 |
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Expiration termination date: 20130630 Granted publication date: 20000112 |