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CN1046191C - A kind of polypeptide health nutrition product and preparation method thereof - Google Patents

A kind of polypeptide health nutrition product and preparation method thereof Download PDF

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CN1046191C
CN1046191C CN94101519A CN94101519A CN1046191C CN 1046191 C CN1046191 C CN 1046191C CN 94101519 A CN94101519 A CN 94101519A CN 94101519 A CN94101519 A CN 94101519A CN 1046191 C CN1046191 C CN 1046191C
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peptone
preparation
hawthorn
product
animal
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CN1107008A (en
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葛赋贵
张力
张�杰
高尚全
李钦
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MEDICINE AND HEALTH-CARE PRODUCTS INST ZHANGJIAKOU MEDICAL COLLEGE
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MEDICINE AND HEALTH-CARE PRODUCTS INST ZHANGJIAKOU MEDICAL COLLEGE
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Abstract

本发明为一种多肽保健营养品及其制备方法。本品主要含有骨胨、肉胨、动物胚胎及胎盘胨、黄芪、陈皮和山楂,其制备方法包括将肉、骨、胚胎及胎盘的浸出液进行酶解、过滤、干燥成胨,将黄芪、陈皮、山楂粉碎混合、煎煮、浓缩、干燥成粉末后与胨混合均匀即可。本品富含多肽、人体所需18种氨基酸及微量元素,具有抗衰老、增强记忆力、恢复体力和精神等功效,且不含任何人工色素、添加剂和防腐剂,本品的制备方法科学合理、简单易行。The invention relates to a polypeptide health nutrition product and a preparation method thereof. This product mainly contains bone peptone, meat peptone, animal embryo and placenta peptone, astragalus, tangerine peel and hawthorn. 1. Hawthorn is crushed and mixed, decocted, concentrated, dried into powder and then mixed with peptone evenly. This product is rich in peptides, 18 kinds of amino acids and trace elements needed by the human body. It has the effects of anti-aging, enhancing memory, restoring physical strength and spirit, and does not contain any artificial colors, additives and preservatives. The preparation method of this product is scientific and reasonable. Simple and easy.

Description

一种多肽保健营养品及其制备方法A kind of polypeptide health nutrition product and preparation method thereof

本发明为一种保健营养品,特别是涉及一种含有多肽的保健营养品及其制备方法。The invention relates to a health nutrition product, in particular to a health nutrition product containing a polypeptide and a preparation method thereof.

随着人民生活水平的日益提高,各种保健营养品层出不穷,但市售的保健营养品多以游离氨基酸为主,其效果单一,且含有人工色素、添加剂、防腐剂等。水解蛋白的生产已有近百年的历史了,水解产物为胨、肽和氨基酸,其中胨为多种肽的混合物,现代研究证明,多肽物质在人体中具有奇妙的功效,它可直接经消化道吸收进入机体,并在体内作为神经递质或调质参与脑细胞的各种功能活动,在心血管活动、内分泌调节方面也起到至关重要的作用,具有提高机体免疫能力,延缓衰老,改善神经功能等功效。With the improvement of people's living standards, various health care products emerge in an endless stream, but most of the health care products available in the market are based on free amino acids, which have a single effect and contain artificial colors, additives, preservatives, etc. The production of hydrolyzed protein has a history of nearly a hundred years. The hydrolyzed products are peptone, peptide and amino acid. Among them, peptone is a mixture of various peptides. Modern research has proved that polypeptide substances have wonderful effects in the human body. It can directly pass through the digestive tract. It is absorbed into the body and participates in various functional activities of brain cells as a neurotransmitter or modulator in the body. It also plays a vital role in cardiovascular activity and endocrine regulation. It can improve the body's immunity, delay aging, and improve nerve function. functions etc.

本发明的目的是提供一种含有多肽物质的保健营养品。The object of the present invention is to provide a health nutrition product containing polypeptide substances.

本发明的另一个目的是提供一种上述营养品的制备方法。Another object of the present invention is to provide a preparation method of the above nutritional product.

本发明的多肽保健营养品含有骨胨、肉胨、动物胚胎及胎盘胨、黄芪、陈皮和山楂,其中各组分的含量(重量)如下:The polypeptide health nutrition product of the present invention contains bone peptone, meat peptone, animal embryo and placenta peptone, astragalus, tangerine peel and hawthorn, wherein the content (weight) of each component is as follows:

骨胨                77-85%Bonetone 77-85%

肉胨                7-15Meat peptone 7-15

动物胚胎及胎盘胨    0.5-1.0%Animal embryo and placenta peptone 0.5-1.0%

黄芪                0.5-1.0%Astragalus 0.5-1.0%

陈皮                0.2-1.0%Tangerine peel 0.2-1.0%

山楂                2-5%Hawthorn 2-5%

本多肽保健营养品中还可以含有0.05-0.1%(重量)的蛋白糖作为甜味剂。The polypeptide health nutrition product can also contain 0.05-0.1% (weight) protein sugar as a sweetener.

所述骨胨可以由牛、羊等畜骨制成。The bone peptone can be made from animal bones such as cattle and sheep.

所述肉胨可以由牛、羊等畜的肌肉制成。The meat peptone can be made from the muscle of cattle, sheep and other livestock.

所述动物胚胎及胎盘胨可以是由牛、羊等畜的胚胎和胎盘制成。The animal embryos and placenta can be made from the embryos and placenta of cattle, sheep and other animals.

所述黄芪具有增强机体免疫力的作用。山楂含有大量苹果酸和维生素C,具有软化血管等功效。在滋补保健方面,黄芪、山楂与多肽起到良好的协同作用。The Radix Astragali has the effect of enhancing the body's immunity. Hawthorn contains a lot of malic acid and vitamin C, which has the effect of softening blood vessels. In terms of nourishing and health care, astragalus, hawthorn and peptides have a good synergistic effect.

所述陈皮主要起到去除腥味、调味的作用。The tangerine peel mainly plays the role of removing fishy smell and seasoning.

本发明的多肽保健营养品实含多种类型的多肽、游离氨基酸、锌、铁、钙、磷、苹果酸、维生素C、维生素B、橙皮甙等,各种成份所含比例适宜,易于机体吸收,且不含任何人工色素、添加剂及防腐剂,且有抗衰老、增强记忆力、改善消化功能、恢复体力及消退老年斑之功效。The polypeptide health nutrition product of the present invention actually contains various types of polypeptides, free amino acids, zinc, iron, calcium, phosphorus, malic acid, vitamin C, vitamin B, hesperidin, etc., and the proportion of various ingredients is suitable, which is easy for the body Absorbable, and does not contain any artificial coloring, additives and preservatives, and has the effects of anti-aging, enhancing memory, improving digestion, restoring physical strength and fading age spots.

本品适用于体弱及病后康复、老年斑、小儿发育不良、脑及精神功能减退、慢性疲劳、植物神经功能紊乱、贫血及慢性消耗性疾病、糖尿病及日常补充营养,This product is suitable for frailty and rehabilitation after illness, senile plaques, children's dysplasia, brain and mental function decline, chronic fatigue, autonomic dysfunction, anemia and chronic wasting disease, diabetes and daily nutritional supplements,

所述多肽保健营养品是这样制备的:将畜骨蒸煮制成胶体状浸出液后除脂、将畜肉搅成肉糜、将动物胚胎和胎盘搅成肉糜状用热水浸出其组织液,分别用胰酶进行酶解,经过滤后将滤液干燥成粉末状的骨胨、肉胨及胚胎和胎盘胨。将黄芪、陈皮、山楂经粉碎、混合、浸泡、煎煮得浸液,再经调PH值、静置过滤、浓缩、干燥得到粉末。将所有原料的粉末按比例均匀混合即为本品。The polypeptide health nutrition product is prepared in the following way: degrease after steaming the animal bone to make a colloidal leachate, stir the animal meat into minced meat, stir the animal embryo and placenta into minced meat, soak the tissue fluid with hot water, and use pancreatic enzymes respectively Carry out enzymatic hydrolysis, filter and dry the filtrate into powdery bone peptone, meat peptone, embryo and placenta peptone. The astragalus, tangerine peel, and hawthorn are ground, mixed, soaked, and decocted to obtain an infusion, and then the pH value is adjusted, filtered, concentrated, and dried to obtain a powder. This product is obtained by mixing the powders of all raw materials evenly in proportion.

本发明方法中所述的酶解一般控制在酶解产物的紫外吸收光谱在210-250nm处有最大吸收峰。用双缩脲法测定,本发明营养品中的多肽含量一般大于50%。The enzymolysis described in the method of the present invention is generally controlled so that the ultraviolet absorption spectrum of the enzymolysis product has a maximum absorption peak at 210-250 nm. As determined by the biuret method, the content of the polypeptide in the nutritional product of the present invention is generally greater than 50%.

本制备方法中所述干燥可以是喷雾干燥。和60℃以下的烘干干燥,优选为喷雾干燥。The drying in this preparation method may be spray drying. And drying below 60°C, preferably spray drying.

所述制备方法中的畜骨的除脂过程可以在油脂分离罐中分离除去油脂部分。In the degreasing process of the animal bones in the preparation method, the fat part can be separated and removed in the fat separation tank.

所述制备方法中的酶解过程可以是将浸出液中加入动物胰脏,调节酶适温度和PH值,使其在胰酶作用下进行消化水解,从而将浸出液分为两部分:大部分是溶于水的胨、多肽、单体氨基酸的混合物,另一小部分为不溶于水的杂蛋白等物。The enzymatic hydrolysis process in the preparation method may be to add animal pancreas to the leachate, adjust the optimum temperature and pH value of the enzyme, and make it digest and hydrolyze under the action of trypsin, thereby dividing the leachate into two parts: most of which are dissolved It is a mixture of peptone, polypeptide, and monomeric amino acid in water, and the other small part is miscellaneous protein that is insoluble in water.

所述制备方法中的将黄芪、陈皮、山楂的浸泡过程可以是用去离子水浸泡1小时;煎煮过程可以进行两次,每次1小时;静置过程可以是24小时;浓缩过程可以是在低温状况下进行。The soaking process of astragalus, tangerine peel, and hawthorn in the described preparation method can be soaked in deionized water for 1 hour; the decocting process can be carried out twice, each 1 hour; the standing process can be 24 hours; the concentration process can be Do it at low temperature.

本品可以制成三种剂形:冲剂、口服液和饮料。冲剂的制备过程是将混合好的本品溶解于蒸馏水中,加入淀粉及蛋白糖混匀后进行喷雾干燥,过筛后即为冲剂;口服液的制备过程是将本品中加入蛋白糖、蔗糖,配成10%的本品的水溶液;饮料的制备过程是将本品制成2%的水溶液后加蛋白糖、橙汁1%及天然食用香精适量即可。This product can be made into three dosage forms: granule, oral liquid and drink. The preparation process of the granule is to dissolve the mixed product in distilled water, add starch and protein sugar, mix well, spray dry, and sieve the granule; the preparation process of the oral liquid is to add protein sugar and sucrose to the product , dubbed into a 10% aqueous solution of this product; the preparation process of the beverage is to make a 2% aqueous solution of this product and then add protein sugar, 1% orange juice and an appropriate amount of natural food flavor.

本品的制备方法科学合理,全部原料均为天然物质,来源广泛,过程简单易行。The preparation method of this product is scientific and reasonable, all raw materials are natural substances, the source is extensive, and the process is simple and easy.

下面结合实施例对本发明进行更详细的描述。The present invention will be described in more detail below in conjunction with examples.

实施例Example

一种多肽保健营养品,它含有牛骨胨、牛肉胨、牛的胚胎及胎盘胨、黄芪、陈皮、山楂和蛋白糖,其中各组分的重量含量如下:A polypeptide health nutrition product, which contains bovine bone peptone, beef peptone, bovine embryo and placenta peptone, astragalus, tangerine peel, hawthorn and protein sugar, wherein the weight content of each component is as follows:

牛骨胨              85%Bovine bone peptone 85%

牛肉胨              10%Beef peptone 10%

牛的胚胎及胎盘胨    0.5%Bovine embryo and placenta peptone 0.5%

黄芪                0.6%Astragalus 0.6%

陈皮                0.5%Tangerine peel 0.5%

山楂                3.4%Hawthorn 3.4%

蛋白糖              0.1%Protein sugar 0.1%

上述多肽保健营养品是这样制成的:将新鲜牛骨进行加压蒸煮,制成胶体状的浸出液,将其导入油脂分离罐分离除去油脂部分,加入动物胰脏,调节酶适温度和PH值,使其在胰酶作用下进行消化水解,从而将其分为两部分:绝大部分是溶于水的胨、肰及单体氨基酸的混合物,小部分为不溶于水的杂蛋白等。用滤纸除去不溶性物质,将滤液经喷雾干燥机喷物制成的浅黄色粉状固形物即为骨胨,它无焦苦味,略有微香,口感好;将剔除了骨骼,并去除脂肪、肌腱、筋膜后的牛肉搅成肉麋后直接用胰酶消化水解,水解后除去不溶性杂蛋白及有影响的无机成份,经喷雾干燥制成浅黄色粉末状的肉胨,它的水溶液有较高的澄清度;将牛的胚胎及胎盘搅成肉糜后用加压热水浸出法浸出其组织液,用上述同样的方法进行酶解、过滤及喷雾干燥,制成浅黄色粉末状的、有浓郁清香气味的胚胎及胎盘胨;将黄芪、陈皮、山楂粉碎后混合,用去离子水浸泡1小时,煎煮两次,每次1小时,合并浸出液,调PH值,静置24小时后过滤,低温浓缩、干燥得到粉末;将以上各种粉末混合均匀,溶解于蒸馏水中,调节PH值,加入蛋白糖混匀,经喷雾干燥,出口温度<80℃,过筛,分装制成冲剂。The above-mentioned polypeptide health nutrition products are made in the following way: fresh beef bones are pressure-cooked to make a colloidal leachate, which is introduced into the oil separation tank to separate and remove the oil part, and the animal pancreas is added to adjust the optimum temperature and pH value of the enzyme. , to make it digested and hydrolyzed under the action of trypsin, thus dividing it into two parts: most of it is a mixture of water-soluble peptone, cassia and monomeric amino acids, and a small part is water-insoluble miscellaneous protein, etc. Use filter paper to remove insoluble substances, and spray the filtrate through a spray dryer to produce a light yellow powdery solid, which is bone peptone. It has no burnt bitterness, a slight fragrance, and a good taste; remove the bones, and remove fat, tendon 1. The beef after the fascia is stirred into meat moose and then directly digested and hydrolyzed with trypsin. After hydrolysis, the insoluble miscellaneous protein and influential inorganic components are removed, and the light yellow powdery meat peptone is made by spray drying. Its aqueous solution has a high Clarity; Stir bovine embryos and placenta into minced meat, then use pressurized hot water leaching method to extract the tissue fluid, use the same method as above for enzymatic hydrolysis, filtration and spray drying, and make light yellow powder with strong fragrance Embryo and placental peptone with odor; crush astragalus, tangerine peel, and hawthorn, mix them, soak in deionized water for 1 hour, decoct twice, each time for 1 hour, combine the leachate, adjust the pH value, and filter after standing for 24 hours. Concentrate and dry to obtain powder; mix the above powders evenly, dissolve them in distilled water, adjust the pH value, add protein sugar and mix well, spray dry, the outlet temperature is less than 80°C, sieve, and pack into granules.

经测定,本品中氨基酸总含量(包括游离氨春酸和多肽中氨基酸的总含量)和微量元素含量如下:氨基酸(克/100克本品)After determination, the total content of amino acids in this product (including the total content of amino acids in free amino spring acid and peptides) and trace elements are as follows: Amino acids (g/100 g of this product)

门冬氨酸5.21    异亮氨酸 1.79Aspartic acid 5.21 Isoleucine 1.79

苏氨酸  1.91    亮氨酸   3.68Threonine 1.91 Leucine 3.68

丝氨酸  2.4%   酪氨酸   1.00Serine 2.4% Tyrosine 1.00

谷氨酸  10.74   苯丙氨酸 2.38Glutamic acid 10.74 Phenylalanine 2.38

甘氨酸  14.46   赖氨酸   3.41Glycine 14.46 Lysine 3.41

丙氨酸  6.65    细氨酸   1.04Alanine 6.65 Leptine 1.04

胱氨酸  0.28    色氨酸   0.21Cystine 0.28 Tryptophan 0.21

缬氨酸  2.78    精氨酸   6.54Valine 2.78 Arginine 6.54

蛋氨酸  1.42    脯按酸   8.24微量元素(mg/kg本品)Methionine 1.42 Proline 8.24 Trace elements (mg/kg of this product)

磷      1314.0  钠  963.0Phosphorus 1314.0 Sodium 963.0

铁      62.9    钾  491.0Iron 62.9 Potassium 491.0

钙      122.0   铝  4.5Calcium 122.0 Aluminum 4.5

镁      197.0   硼  0.7Magnesium 197.0 Boron 0.7

锰      121.0   锶  0.7Manganese 121.0 Strontium 0.7

铜      2.6     锂  22.7Copper 2.6 Lithium 22.7

锌      9.2     镧  0.2Zinc 9.2 Lanthanum 0.2

硅      44.3    铬  0.5Silicon 44.3 Chromium 0.5

Claims (7)

1、一种多肽保健营养品,其特征是它含有骨胨、肉胨,动物胚胎和胎盘胨、黄芪、陈皮和山楂,其中各组分的重量含量如下:1, a kind of polypeptide health nutrition product, it is characterized in that it contains bone peptone, meat peptone, animal embryo and placenta peptone, astragalus, tangerine peel and hawthorn, wherein the weight content of each component is as follows: 骨胨                77-85%Bonetone 77-85% 肉胨                7-15%Meat peptone 7-15% 动物胚胎及胎盘胨     0.5-1.0%Animal embryo and placenta peptone 0.5-1.0% 黄芪                0.5-1.0%Astragalus 0.5-1.0% 陈皮                0.2-1.0%Tangerine peel 0.2-1.0% 山楂                2-5%Hawthorn 2-5% 2、如权利要求1所述的营养品,其特征是还含有0.05-0.1%的蛋白糖。2. The nutritional product according to claim 1, characterized in that it also contains 0.05-0.1% protein sugar. 3、如权利要求1所述的多肽保健营养品的制备方法,其特征是它包括将畜骨蒸煮制成胶体状浸出液后除脂,用胰酶进行酶解,过滤后将滤液干燥成粉末;将畜肉搅成肉糜,用胰酶进行酶解,过滤后将滤液干燥成粉末状;将动物胚胎和胎盘搅成肉糜后用胰酶进行酶解,过滤后将滤液干燥成粉末状;将黄芪、陈皮、山楂经粉碎、混合、浸泡、煎煮得浸液,静置、过滤、浓缩、干燥得粉末;将所有粉末混合均匀。3. The preparation method of polypeptide health-care nutritional products as claimed in claim 1, characterized in that it comprises cooking the animal bones to make a colloidal leachate, removing fat, enzymatically hydrolyzing with trypsin, and drying the filtrate into powder after filtering; Stir livestock meat into minced meat, perform enzymolysis with trypsin, filter and dry the filtrate into powder; stir animal embryos and placenta into mince, then use trypsin to enzymolyze, filter and dry the filtrate into powder; The tangerine peel and hawthorn are crushed, mixed, soaked, and decocted to obtain an infusion, and then left to stand, filtered, concentrated, and dried to obtain a powder; all the powders are mixed evenly. 4、如权利要求3所述的制备方法,其特征在于所述干燥为喷雾干燥。4. The preparation method according to claim 3, characterized in that said drying is spray drying. 5、如权利要求3所述的制备方法,其特征在于所述酶解是将浸出液中加入动物胰脏,调节酶适温度和PH值,使其胰酶作用下进行消化水解。5. The preparation method according to claim 3, characterized in that the enzymatic hydrolysis is adding animal pancreas to the leaching solution, adjusting the optimum temperature and pH value of the enzyme, so that it can be digested and hydrolyzed under the action of pancreatic enzymes. 6、如权利要求3所述的制备方法,其特征在于将黄芪、陈皮、山楂用去离子水浸泡1小时,煎煮两次,每次1小时,合并两次煎煮液,调节PH值,静置24小时后过滤。6. The preparation method as claimed in claim 3, characterized in that astragalus, tangerine peel, and hawthorn are soaked in deionized water for 1 hour, decocted twice for 1 hour each time, and the decoctions are combined twice to adjust the pH value. After standing for 24 hours, filter. 7、如权利要求3所述的制备方法,其特征在于在低温下进行浓缩。7. The preparation method as claimed in claim 3, characterized in that the concentration is carried out at low temperature.
CN94101519A 1994-02-21 1994-02-21 A kind of polypeptide health nutrition product and preparation method thereof Expired - Fee Related CN1046191C (en)

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CN1065724C (en) * 1998-04-07 2001-05-16 黑龙江省完达山食品厂 Cow placenta health care foods and production method
CN108308620A (en) * 2018-03-27 2018-07-24 张至德 The method that edible protein enzyme digests animal organ and bone prepares functional peptide food

Citations (3)

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Publication number Priority date Publication date Assignee Title
JPS527458A (en) * 1975-07-01 1977-01-20 Tensei Suisan Kk Method of extracting animal extract
CN88101423A (en) * 1987-03-20 1988-10-05 制铁化学工业株式会社 Edible composition
CN1080486A (en) * 1992-07-01 1994-01-12 天津医学院 Xin oyster nature nutrition oral liquid and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS527458A (en) * 1975-07-01 1977-01-20 Tensei Suisan Kk Method of extracting animal extract
CN88101423A (en) * 1987-03-20 1988-10-05 制铁化学工业株式会社 Edible composition
CN1080486A (en) * 1992-07-01 1994-01-12 天津医学院 Xin oyster nature nutrition oral liquid and preparation method thereof

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