CN104306907A - A kind of traditional Chinese medicine compound powder for resisting infantile convulsions and preparation method thereof - Google Patents

Abstract

The compound Chinese medicine powder for resisting infantile convulsion is prepared with costustoot 1-3 weight portions, frankincense 1-3 weight portions, cinnabar 1-2 weight portions, airpotato yam 1-2 weight portions, figwortflower picrorhiza rhizome 1-3 weight portions, ephedra 1-3 weight portions, burred tuber 1-3 weight portions, zedoary 1-3 weight portions, Chuanxiong rhizome 1-3 weight portions, Chinese honeylocust spine 1-3 weight portions, trichosanthes fruit 1-2 weight portions, pepperweed seed 1-3 weight portions and clove 1-3 weight portions. The cinnabar is processed by a water-flying process and is sieved by a 200-mesh sieve, so that the toxicity is reduced, and other medicinal ingredients are subjected to superfine grinding, so that the dissolution and absorption degree of an oral preparation in vivo can be increased, the bioavailability of the medicine is improved, the dosage is reduced, raw materials are saved, the efficiency is improved, and the cost is reduced.

Description

A kind of traditional Chinese medicine compound powder for resisting infantile convulsions and preparation method thereof

technical field

The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a traditional Chinese medicine compound powder for fighting convulsions in children and a preparation method thereof.

Background technique

Convulsions in children is a common acute and severe disease in children, characterized by convulsions and coma. Also known as "convulsions", the common name is "convulsions". It can occur in any season, and it is more common in children aged 1-5. The younger the age, the higher the incidence rate. The evidence is often dangerous and changes rapidly, threatening the life of children. Therefore, ancient doctors believed that convulsions were a bad weather. For example, "Tongyi Baojian · Children" said: "The most dangerous disease in children is that there is no evidence of shock." "Children's Interpretation of Mysteries·Convulsions" also said: "The most serious disease in children is shock."

Clinically, it can be divided into eight syndromes. The so-called eight seasons are twitching, pinching, trembling, pulling, turning, leading, fleeing, and seeing. The appearance of the eighth hour indicates that the convulsion has already occurred. However, when convulsions occur, not all of them appear in all eight periods. Because the onset of convulsions can be urgent or slow, and the symptoms of syndromes can be either virtual or solid, cold or hot, so clinical syndromes often divide convulsions into acute convulsions and slow convulsions. Those who have a sudden onset of illness, which belong to yang and are true, are collectively referred to as Jijingfeng; those who are slow in progression and belong to yin and deficiency, are collectively referred to as slow convulsions. Primary disease Western medicine claims infantile convulsion. Among them, those with fever are mostly caused by infectious diseases. Common intracranial infectious diseases include meningitis, brain abscess, encephalitis, and cerebral parasitic diseases; (such as toxic bacillary dysentery, toxic pneumonia, sepsis, etc.). Those without fever are mostly caused by non-infectious diseases. In addition to common epilepsy, there are water and electrolyte disorders, hypoglycemia, drug poisoning, food poisoning, genetic metabolic diseases, traumatic brain injury, and brain tumors.

At present, there are many medicines for treating infantile convulsions in the market. This prescription is traditional Chinese medicine compound powder for treating infantile convulsions. Traditional Chinese medicine pills and powders account for a considerable proportion of solid preparations. The traditional processing technology makes the drug particle size mostly 125-180 μm, which is not conducive to the full absorption of active ingredients. The use of traditional Chinese medicine ultrafine grinding can make the fineness of Chinese medicine Achieving more than 300 mesh, or even smaller, can significantly increase the degree of dissolution and absorption of oral preparations in the body, and it is possible to achieve or exceed the curative effect of the original prescription with a smaller dose, save raw materials, improve efficiency, reduce costs, and help retain biological activity Element.

Contents of the invention

The object of the present invention is to provide a Chinese medicine compound powder for resisting convulsions in children and a preparation method thereof.

The object of the present invention is achieved through the following technical solutions: a Chinese medicine compound powder for resisting infantile convulsions, raw materials in parts by weight, 1-3 parts of woody incense, 1-3 parts of frankincense, 1-2 parts of cinnabar, 1-2 parts of xanthophyll 2 parts, 1-3 parts of Huhuanglian, 1-3 parts of Ephedra, 1-3 parts of Sanleng, 1-3 parts of Curcuma, 1-3 parts of Chuanxiong, 1-3 parts of saponins, 1-2 parts of Trichosanthes, Tinglizi 1-3 parts, cloves 1-3 parts.

Described a kind of traditional Chinese medicine compound powder for resisting convulsions in children, raw material according to optimal weight parts: 2 parts of woody incense, 2 parts of frankincense, 1 part of cinnabar, 1 part of xanthophyllum, 2 parts of Huhuanglian, 2 parts of ephedra, 2 parts, 2 parts of Curcuma, 2 parts of Chuanxiong, 2 parts of saponins, 1 part of Trichosanthes, 2 parts of Tinglizi, 2 parts of cloves.

Described a kind of anti-convulsion Chinese medicine compound powder and preparation method thereof, the specific steps of its preparation method are:

Step 1: In parts by weight, take high-quality woody incense, frankincense, cinnabar, xanthophyllum, ephedra, sanleng, zedoary, chuanxiong, saponin, melon, tinglizi, clove, wash and remove impurities ,spare;

Step 2: Prepare cinnabar powder: crush cinnabar, put it in a mortar, add appropriate amount of water, grind it into a paste, then add appropriate amount of water and stir, the coarse powder will sink, and the fine powder will be suspended in the solution, pour out the suspension immediately , grind the sinking coarse powder again, and repeat this many times until it is finely ground, and finally discard the unsuspendable impurities, combine the suspensions poured out before and after and let stand, after precipitation, pour off the top dry the precipitate at a temperature of 60°C, grind it into a very fine powder, and pass it through a 200-mesh sieve;

Step 3: Grind woody incense, frankincense, xanthogonia, berberine, ephedra, sanleng, zedoary, chuanxiong, saponins, melon, tinglizi, and cloves to a diameter of less than 10 μm, that is, more than 300 mesh The powder is uniformly mixed with cinnabar powder, sterilized by ultraviolet rays, and packed into bags to prepare a traditional Chinese medicine compound powder for resisting convulsions in children.

In the medicine: woody fragrance, promoting qi and relieving pain, adjusting the middle and leading to stagnation, main cell and hypochondrium swelling and satisfaction, epigastric distension and pain, belching and diarrhea, severe after dysentery, used for distending pain in the chest and abdominal cavity, severe after diarrhea, indigestion, Not thinking about diet, frankincense, regulating qi and promoting blood circulation, relieving pain, chasing toxins, treating stagnation of qi and blood, subordinate pain, carbuncle sores, swollen toxins, bruises, dysmenorrhea, postpartum blood stasis and tingling, xanthate, phlegm and stagnation, cooling blood Hemostasis, Huhuanglian, clearing heat, cooling blood, drying dampness, treating malnutrition, convulsions, diarrhea, hot bone steaming, spontaneous sweating, night sweats, vomiting blood, epistaxis, fire eyes, hemorrhoids, sores, ephedra, sweating powder Cold, dispersing lung and relieving asthma, diuresis and detumescence, triangular, treating abdominal mass accumulation, qi and blood stagnation, confidant pain, hypochondriac pain, amenorrhea, postpartum blood stasis and abdominal pain, bruises, sores and hard swelling, curcuma, broken Promoting blood and qi, eliminating stagnation and relieving pain, used for abdominal pain due to blood stasis, hepatosplenomegaly, distending pain in trusted subordinates, accumulation, amenorrhea due to blood stasis in women, pain from bruises and food stagnation, Rhizoma Chuanxiong, promoting qi to relieve depression, fafeng drying dampness, Promoting blood circulation and relieving pain, treating wind-cold headache, dizziness, hypochondriac pain, abdominal pain, cold arthralgia, cramps, amenorrhea, dystocia, postpartum stasis block pain, carbuncle sores, used for irregular menstruation, amenorrhea dysmenorrhea, abdominal pain, chest and flank pain Stinging pain, tumbling and swelling, headache, rheumatic arthralgia, saponins thorn, promoting blood circulation and expelling wind, reducing swelling and pain, Gualou, antipyretic and thirst quenching, diuretic, antitussive and expectorant, Tinglizi, purging lung and lowering qi, Eliminates phlegm and relieves asthma, promotes diuresis to reduce swelling, expels evil, cloves, warms the middle, warms the kidneys, lowers adverse events, treats hiccups, vomiting, nausea, dysentery, cold pain in trusted subordinates, obsession, hernia, ringworm.

Beneficial effects: the traditional Chinese medicine compound powder for resisting convulsions in children according to the present invention has the effects of antipyretic and convulsion-relieving, reducing adverse events and relieving cough, and can be used for fever, cough and convulsions in children. Mesh sieve to reduce toxicity, and other medicinal flavors are ultrafinely pulverized, which can increase the degree of dissolution and absorption of oral preparations in the body, improve the bioavailability of drugs, reduce dosage, save raw materials, improve efficiency, and reduce costs.

The present invention is clinically verified by two groups, one of which is the treatment group taking the present invention, taking the present invention once a day, 7 days is a course of treatment, and the other group of control group is taking Zhenjing Anshen Oral Liquid, using it once a day, 7 days is a course of treatment. For the course of treatment, 110 outpatients were selected for each group, including 40 males and 70 females, the oldest was 75 years old, and the youngest was 35 years old. , convulsions and weakness, Table 1 is the control data after taking a course of treatment:

Table 1 Comparison of the course of treatment of the two groups before and after taking (unit: person)

There is a significant difference between the treatment group and the control group, so it can be seen that the clinical application of the present invention has a significant curative effect.

The process characteristics of the present invention: 1. Scientific selection of raw materials, advanced production technology, and convenient storage and use of the product; 2. The medicinal ingredients in the product are easily absorbed by the human body; 3. Wide source of raw materials, short processing line, and easy processing and manufacturing of the product.

Detailed ways

Example 1

A traditional Chinese medicine compound powder for fighting convulsions in children, raw materials in parts by weight, 1-3 parts of woody incense, 1-3 parts of frankincense, 1-2 parts of cinnabar, 1-2 parts of xanthophyll, 1-3 parts of Huhuanglian, ephedra 1-3 parts, 1-3 parts of Sanleng, 1-3 parts of Curcuma, 1-3 parts of Chuanxiong, 1-3 parts of saponins, 1-2 parts of Trichosanthes, 1-3 parts of Tinglizi, 1-3 parts of cloves 3 copies.

Example 2

A traditional Chinese medicine compound powder for fighting convulsions in children. The raw materials are according to the optimal weight parts: 2 parts of woody incense, 2 parts of frankincense, 1 part of cinnabar, 1 part of xanthophyllum, 2 parts of Huhuanglian, 2 parts of ephedra, 2 parts of trigonum, 2 parts of curcuma, 2 parts of Chuanxiong, 2 parts of saponins, 1 part of melon, 2 parts of Tinglizi, and 2 parts of cloves.

Example 3

A traditional Chinese medicine compound powder for resisting infantile convulsions and a preparation method thereof, the specific steps of the preparation method are:

Step 1: In parts by weight, take high-quality woody incense, frankincense, cinnabar, xanthophyllum, ephedra, sanleng, zedoary, chuanxiong, saponin, melon, tinglizi, clove, wash and remove impurities ,spare;

Step 2: Prepare cinnabar powder: crush cinnabar, put it in a mortar, add appropriate amount of water, grind it into a paste, then add appropriate amount of water and stir, the coarse powder will sink, and the fine powder will be suspended in the solution, pour out the suspension immediately , grind the sinking coarse powder again, and repeat this many times until it is finely ground, and finally discard the unsuspendable impurities, combine the suspensions poured out before and after and let stand, after precipitation, pour off the top dry the precipitate at a temperature of 60°C, grind it into a very fine powder, and pass it through a 200-mesh sieve;

Step 3: Grind woody incense, frankincense, xanthogonia, berberine, ephedra, sanleng, zedoary, chuanxiong, saponins, melon, tinglizi, and cloves to a diameter of less than 10 μm, that is, more than 300 mesh The powder is uniformly mixed with cinnabar powder, sterilized by ultraviolet rays, and packed into bags to prepare a traditional Chinese medicine compound powder for resisting convulsions in children.

Claims (3)

1. A traditional Chinese medicine compound powder for resisting infantile convulsions, characterized in that: raw materials in parts by weight, 1-3 parts of woody incense, 1-3 parts of frankincense, 1-2 parts of cinnabar, 1-2 parts of xanthophyll, 1-2 parts of Coptis chinensis 1-3 parts, 1-3 parts of Ephedra, 1-3 parts of Sanleng, 1-3 parts of Curcuma, 1-3 parts of Chuanxiong, 1-3 parts of saponins, 1-2 parts of Trichosanthes, 1-3 parts of Tinglizi 3 parts, 1-3 parts of cloves. 2. A kind of traditional Chinese medicine compound powder for resisting convulsions in children according to claim 1, characterized in that: the raw materials are in optimal parts by weight: 2 parts of woody incense, 2 parts of frankincense, 1 part of cinnabar, 1 part of xanthophyll, 1 part of pedicel 2 parts of coptis, 2 parts of ephedra, 2 parts of sanleng, 2 parts of curcuma, 2 parts of chuanxiong, 2 parts of saponins, 1 part of melon, 2 parts of Tinglizi, and 2 parts of cloves. 3. a kind of anti-convulsion Chinese medicine compound powder according to claim 1-2, is characterized in that: the concrete steps of its preparation method are: Step 1: In parts by weight, take high-quality woody incense, frankincense, cinnabar, xanthophyllum, ephedra, sanleng, zedoary, chuanxiong, saponin, melon, tinglizi, clove, wash and remove impurities ,spare; Step 2: Prepare cinnabar powder: crush cinnabar, put it in a mortar, add appropriate amount of water, grind it into a paste, then add appropriate amount of water and stir, the coarse powder will sink, and the fine powder will be suspended in the solution, pour out the suspension immediately , grind the sinking coarse powder again, and repeat this many times until it is finely ground, and finally discard the unsuspendable impurities, combine the suspensions poured out before and after and let stand, after precipitation, pour off the top dry the precipitate at a temperature of 60°C, grind it into a very fine powder, and pass it through a 200-mesh sieve; Step 3: Grind woody incense, frankincense, xanthogonia, berberine, ephedra, sanleng, zedoary, chuanxiong, saponins, melon, tinglizi, and cloves to a diameter of less than 10 μm, that is, more than 300 mesh The powder is mixed evenly with cinnabar powder, packed into bags, and a kind of traditional Chinese medicine compound powder for resisting convulsions in children is prepared.