CN104305985A - Low-power-consumption heart rate monitor and monitoring method thereof - Google Patents
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Abstract
本发明公开了一种低功耗心率监测仪及其监测方法,包括三运放五级低功耗心电提取电路、单片机、显示模块、低功耗蓝牙芯片模块和移动端,基于MSP430F5529超低功耗单片机,通过提取I导联心电信号,用差分法检测R波来实现心率计算和显示,且能显示波形,报警,并通过串口或蓝牙传送数据和心电图像。可采用3V~4.5V电池供电,选用了有源与无源结合的三运放五级信号提取电路和蓝牙4.0BLE模块,是低功耗的。测试结果表明本系统提取的心电信号失真小,心率测算准确,具有很好的推广利用前景。The invention discloses a low-power heart rate monitor and a monitoring method thereof, including a three-stage five-stage low-power ECG extraction circuit, a single-chip microcomputer, a display module, a low-power bluetooth chip module and a mobile terminal, based on MSP430F5529 ultra-low Power-consumption single-chip microcomputer, by extracting the I-lead ECG signal, using the differential method to detect the R-wave to realize heart rate calculation and display, and can display waveforms, alarm, and transmit data and ECG images through serial ports or Bluetooth. It can be powered by a 3V~4.5V battery, and uses a combination of active and passive three-op-amp five-level signal extraction circuit and Bluetooth 4.0BLE module, which is low power consumption. The test results show that the ECG signal extracted by this system has little distortion and accurate heart rate calculation, which has a good prospect of popularization and utilization.
Description
技术领域 technical field
本发明涉低功耗心率监测仪领域,尤其涉及一种低功耗心率监测仪及其监测方法。 The present invention relates to the field of low-power heart rate monitors, in particular to a low-power heart rate monitor and a monitoring method thereof.
背景技术 Background technique
心率监测是生活中和临床上常用的,它在运动强度检测、体质检测、疾病诊断等方面有重要用途。心电波形则有更大的临床价值。如果能够把心率和心电的数据收集起来,做长期的分析,则有更大的临床和科研价值。但是,由于心电信号是低信噪比的周期性微弱信号,在采集过程中容易受到仪器、人体等方面的影响,并混有很强的工频干扰,所以需要有一定提取能力的信号提取电路。 Heart rate monitoring is commonly used in life and clinical practice. It has important uses in exercise intensity detection, physical fitness detection, and disease diagnosis. ECG waveform has greater clinical value. If the heart rate and ECG data can be collected for long-term analysis, it will have greater clinical and scientific value. However, since the ECG signal is a periodic weak signal with a low signal-to-noise ratio, it is easily affected by instruments, human bodies, etc. during the acquisition process, and mixed with strong power frequency interference, so a signal extraction with a certain extraction ability is required circuit.
现有的市售心率检测仪,往往功能单一,缺乏心率之外的一些实用的附加功能;数据只能显示而不能传输或记录,适用范围窄;若实现较多功能,则功耗又容易偏高。因而开发一种能克服上述缺点的心率监测仪是很有价值的。 Existing commercially available heart rate detectors often have a single function and lack some practical additional functions other than heart rate; the data can only be displayed but not transmitted or recorded, and the scope of application is narrow; if more functions are implemented, the power consumption will easily be biased. high. It would therefore be valuable to develop a heart rate monitor that overcomes the above-mentioned shortcomings.
发明内容 Contents of the invention
本发明所要解决的技术问题在于提供一种便携、日用的低功耗心率监测仪,更适用于人们平时日常健康测量监控所需。该低功耗心率监测仪结构简单,可通过操控显示器旁的三个按钮进行监测功能的切换,向用户提供心率实时次数、心率30秒平均次数、心电波形、ST波间隔、心率过低或过高提醒等多种 The technical problem to be solved by the present invention is to provide a portable, daily-use low-power heart rate monitor, which is more suitable for people's daily health measurement and monitoring needs. The low-power heart rate monitor has a simple structure, and can switch the monitoring function by manipulating the three buttons next to the display, providing users with real-time heart rate times, 30-second average heart rate times, ECG waveforms, ST wave intervals, low heart rate or Too high reminder and many other
实用功能。 utility function.
本发明的技术方案如下: The technical scheme of the present invention is as follows:
低功耗心率监测仪包括三运放五级低功耗心电提取电路、单片机 、显示模块、低功耗蓝牙芯片模块和移动端,连接人体的I导联线套在三运放五级低功耗心电提取电路的铜针上,三运放五级低功耗心电提取电路的输出级与单片机通过杜邦线相连, 单片机处理后的心电参数与波形,一方面展现在显示模块上,另一方面通过串口或蓝牙模块传送心电参数与波形至移动端。 The low-power heart rate monitor includes a three-stage five-stage low-power ECG extraction circuit, a single-chip microcomputer, a display module, a low-power Bluetooth chip module and a mobile terminal. On the copper needle of the power consumption ECG extraction circuit, the output stage of the three-op-amp and five-stage low-power consumption ECG extraction circuit is connected to the single-chip microcomputer through DuPont lines, and the ECG parameters and waveforms processed by the single-chip microcomputer are displayed on the display module on the one hand. , and on the other hand, transmit ECG parameters and waveforms to the mobile terminal through the serial port or Bluetooth module.
所述的单片机为MSP430F5529单片机,显示模块是Nokia5110显示模块,低功耗蓝牙芯片模块是CC2540/2541低功耗蓝牙芯片模块。 The single-chip microcomputer is an MSP430F5529 single-chip microcomputer, the display module is a Nokia5110 display module, and the low-power bluetooth chip module is a CC2540/2541 low-power bluetooth chip module.
所述的三运放五级低功耗心电提取电路包括顺次相连的电源转换模块、差分放大电路模块、1Hz高通滤波模块、100Hz低通滤波模块、50Hz工频陷波模块和放大与电平抬升模块。 The described three-op-amp five-level low-power ECG extraction circuit includes sequentially connected power conversion modules, differential amplifier circuit modules, 1Hz high-pass filter modules, 100Hz low-pass filter modules, 50Hz power frequency notch modules, and amplification and electrical circuits. Lift the module flat.
所述的电源转换模块采用TPS60400充电泵电压反向器,差分放大电路模块中的运放采用的是INA126差分仪表放大器,100Hz低通滤波模块采用的运算放大器是OPA227运算放大器,放大与电平抬升模块采用的运算放大器是OPA333运算放大器。 The power conversion module uses a TPS60400 charge pump voltage inverter, the operational amplifier in the differential amplifier circuit module uses an INA126 differential instrument amplifier, and the operational amplifier used in the 100Hz low-pass filter module is an OPA227 operational amplifier. The operational amplifier used in the module is OPA333 operational amplifier.
所述的100Hz低通滤波模块采用的是二阶有源巴特沃斯滤波器,1Hz高通滤波模块采用的是一阶无源巴特沃斯滤波器,50Hz工频险波模块采用的是无源双T型陷波滤波器。 The 100Hz low-pass filter module uses a second-order active Butterworth filter, the 1Hz high-pass filter module uses a first-order passive Butterworth filter, and the 50Hz industrial frequency dangerous wave module uses a passive dual T-shaped notch filter.
所述的MSP430F5529超低功耗单片机的软件处理包括计时与采样、50Hz数字滤波、差分法R波检测、即时心率和平均心率的计算、R波检测阈值自学习、系统初始化设定与低功耗控制、按键检测、ST波间隔检测、液晶驱动、心率界面与心率输出、波形界面显示和报警界面显示、设定界面的显示、报警灯开关设定、背光开关设定、UART串口发送开关设定、UART串口数据编码、UART串口数据发送至低功耗蓝牙芯片模块。 The software processing of the MSP430F5529 ultra-low-power single-chip microcomputer includes timing and sampling, 50Hz digital filtering, R-wave detection by differential method, calculation of real-time heart rate and average heart rate, self-learning of R-wave detection threshold, system initialization setting and low power consumption. Control, button detection, ST wave interval detection, LCD drive, heart rate interface and heart rate output, waveform interface display and alarm interface display, setting interface display, alarm light switch setting, backlight switch setting, UART serial port sending switch setting , UART serial port data encoding, UART serial port data sent to the low-power Bluetooth chip module.
所述移动端APP/HeartRate能接收低功耗蓝牙芯片模块发送的数据、进行数据解码、显示即时心率、平均心率、ST间隔数据和心电波形。 The mobile APP/HeartRate can receive the data sent by the low-power bluetooth chip module, decode the data, and display the real-time heart rate, average heart rate, ST interval data and ECG waveform.
所述低功耗蓝牙芯片模块与移动端APP进行数据传输是基于蓝牙4.0协议。 The data transmission between the Bluetooth low-power chip module and the mobile APP is based on the Bluetooth 4.0 protocol.
所述心率监测仪的低功耗心率监测方法,其特征在于利用I导联线提取I导联心电信号,经过三运放五级低功耗心电提取电路进行前置信号处理,进行心电信号的放大、滤波与电平抬升,然后将电路输出信号传入单片机,单片机采用500次/s的采样频率,带有按键检测,并对输入的心电信号进行50Hz数字滤波,单片机利用差分法R波检测来进行心率计算,于显示屏上进行波形与数据的显示,最后通过低功耗蓝牙芯片模块,将心电参数与心电波形传输到移动端APP显示。 The low power consumption heart rate monitoring method of the heart rate monitor is characterized in that it utilizes the I lead line to extract the I lead electrocardiogram signal, and carries out pre-signal processing through the five-level low power consumption electrocardiogram extraction circuit of the three op-amps, and carries out the electrocardiogram signal. Amplify, filter and level up the electrical signal, and then transmit the output signal of the circuit to the single-chip microcomputer. The single-chip microcomputer adopts a sampling frequency of 500 times/s, with key detection, and performs 50Hz digital filtering on the input ECG signal. The single-chip microcomputer uses differential The heart rate is calculated by R wave detection, and the waveform and data are displayed on the display screen. Finally, the ECG parameters and ECG waveform are transmitted to the mobile APP for display through the low-power Bluetooth chip module.
所述心率监测仪的低功耗心率监测方法中按键检测通过P1.2(主按键),P1.3和P1.4(两个辅助按键)的中断来完成。按键按下时相应IO口接地,产生下降沿中断。之后立即将中断标志复位,将按键按下信息保存到中间变量中,处理完按键后再把中间变量复位。 In the low power consumption heart rate monitoring method of the heart rate monitor, key detection is accomplished through the interruption of P1.2 (main key), P1.3 and P1.4 (two auxiliary keys). When the button is pressed, the corresponding IO port is grounded, and a falling edge interrupt is generated. Immediately after that, the interrupt flag is reset, and the button press information is saved in the intermediate variable, and the intermediate variable is reset after the button is processed.
所述心率监测仪的低功耗心率监测方法中计时通过MSP430自带的Timer_B计时器实现的,每1/500s,通过定时器中断唤醒低功耗模式LPM0状态下的MCU来工作。用一个计时变量从0到29999循环增计数,获得1分钟内的时间。 In the low power consumption heart rate monitoring method of the heart rate monitor, the timing is realized by the Timer_B timer carried by the MSP430, and every 1/500s, the MCU in the low power mode LPM0 state is woken up by the timer interrupt to work. Use a timing variable to increase the count from 0 to 29999 to obtain the time within 1 minute.
所述心率监测仪的低功耗心率监测方法中R波检测是利用心电波形中R波上升沿比其他波形上升沿陡峭许多的特点,采用二阶差分法来检测心电波形中的R波。 In the low power consumption heart rate monitoring method of the heart rate monitor, the R wave detection utilizes the characteristic that the rising edge of the R wave in the ECG waveform is much steeper than the rising edge of other waveforms, and uses the second-order difference method to detect the R wave in the ECG waveform .
所述心率监测仪的低功耗心率监测方法通讯输出采用的是MSP430F5529自带的UART串口(配置其波特率为115200),以一定的字符串格式,输出即时心率、平均心率和心电的数据。 The low-power heart rate monitoring method of the heart rate monitor uses the UART serial port of the MSP430F5529 (configured with a baud rate of 115200) for communication output, and outputs the real-time heart rate, average heart rate and ECG in a certain string format. data.
本发明的有益效果是,可以在人们日常生活中对其心电参数正常情况进行便捷地检测与监控,并具有结构简单、功耗较低和使用方便等特点。 The beneficial effect of the present invention is that it can conveniently detect and monitor the normal conditions of ECG parameters in people's daily life, and has the characteristics of simple structure, low power consumption and convenient use.
附图说明 Description of drawings
下面结合附图对本发明进一步说明。 Below in conjunction with accompanying drawing, the present invention is further described.
图1是低功耗心率监测仪结构示意图; Figure 1 is a schematic structural diagram of a low-power heart rate monitor;
图2是本发明前置差分放大电路和1Hz的高通滤波器的电路图; Fig. 2 is the circuit diagram of the pre-differential amplifier circuit of the present invention and the high-pass filter of 1Hz;
图3是本发明截止频率为100Hz的低通滤波器的电路图; Fig. 3 is a circuit diagram of a low-pass filter with a cut-off frequency of 100Hz in the present invention;
图4是本发明最终放大与电平抬升电路的电路图; Figure 4 is a circuit diagram of the final amplification and level raising circuit of the present invention;
图5是本发明50Hz工频陷波器的电路图; Fig. 5 is a circuit diagram of the 50Hz power frequency notch filter of the present invention;
图6是本发明负电源转换模块的电路图; Figure 6 is a circuit diagram of the negative power conversion module of the present invention;
图7是本发明心率计算核心算法原理图; Figure 7 is a schematic diagram of the heart rate calculation core algorithm of the present invention;
图8是本发明APP界面结构图。 Figure 8 is a structural diagram of the APP interface of the present invention.
图中:三运放五级式低功耗心电提取电路1, MSP430F5529单片机2,供电电源3,Nokia5110显示模块4,用户操作按钮5,部件间连接线6,心率数据显示7,心电波形显示8。 In the figure: three operational amplifiers and five-stage low-power ECG extraction circuit 1, MSP430F5529 microcontroller 2, power supply 3, Nokia5110 display module 4, user operation buttons 5, connecting wires between components 6, heart rate data display 7, ECG waveform 8 is displayed.
具体实施方式 Detailed ways
下面结合附图1到图8对本发明作进一步说明。 The present invention will be further described below in conjunction with accompanying drawing 1 to Fig. 8.
图1展示了本系统的基本原理。本系统通过有源与无源结合的三运放五级信号放大与滤波电路对信号进行提取,通过五点差分法检测心电波形中的R波,之后进行显示与数据传输,并实现一些附加功能。供电电源可为两节1.5V干电池。 Figure 1 shows the basic principle of the system. This system extracts the signal through the combination of active and passive three-stage five-stage signal amplification and filter circuit, and detects the R wave in the ECG waveform through the five-point difference method, and then displays and transmits data, and realizes some additional functions. Function. The power supply can be two 1.5V dry batteries. the
图2中,一种低功耗心率监测仪包括图2左上部分的三运放五级式低功耗心电提取电路、图2右上部的供电电池、图2左下部的单片机计算与控制模块,和图2右下部的显示屏与控制按钮。图2左上部分三运放五级式低功耗心电提取电路由前置差分放大电路、截止频率为1Hz的高通滤波器、截止频率为100Hz的低通滤波器、50Hz工频陷波器和最终放大与电平抬升电路组成。图2右上部的供电部分采用2节1.5V干电池实现,其中心电信号提取电路所用的负电源是通过TPS60400充电泵电压反向器实现的。图2左下部的单片机计算与控制模块采用MSP430F5529单片机实现。MSP430系列单片机是一种低功耗的16位单片机,可采用3V供电,外设模块丰富,适合本心率计的实现。又可再分为心率计算和系统流程控制两大部分。图2右下部分为输出部分。包括显示器输出和通讯输出。显示器输出即时心率、平均心率、心电波形、报警信息以及一些设置信息。所采用的显示器为Nokia5110模块。通讯输出采用的是MSP430F5529自带的UART串口,以一定的字符串格式,输出心率(即时、平均)和心电的数据。如果将UART串口与USB转UART模块相连,就可以向电脑发送数据。如果将UART串口与蓝牙串口透传模块相连,就可以在手机等蓝牙设备上看到心率。本系统采用的是一款基于TI公司CC252541低功耗蓝牙芯片的模块——济南华茂公司生产的HM-11蓝牙4.0 BLE低功耗蓝牙串口透传模块。并在安卓系统上实现了瞬时心率和平均心率的显示。 In Fig. 2, a low-power heart rate monitor includes a three-op-amp five-stage low-power ECG extraction circuit in the upper left part of Fig. 2, a power supply battery in the upper right part of Fig. 2, and a single-chip computing and control module in the lower left part of Fig. 2 , and the display screen and control buttons in the lower right part of Figure 2. Figure 2 The upper left part of the three-op-amp five-stage low-power ECG extraction circuit consists of a pre-differential amplifier circuit, a high-pass filter with a cut-off frequency of 1Hz, a low-pass filter with a cut-off frequency of 100Hz, a 50Hz power frequency notch filter and The final amplification and level boosting circuit is composed. The power supply part in the upper right part of Figure 2 is realized by two 1.5V dry batteries, and the negative power supply used by the central electric signal extraction circuit is realized by the TPS60400 charge pump voltage inverter. The single-chip computer calculation and control module in the lower left part of Fig. 2 is realized by MSP430F5529 single-chip computer. MSP430 series single-chip microcomputer is a 16-bit single-chip microcomputer with low power consumption, which can be powered by 3V, and has rich peripheral modules, which is suitable for the realization of this heart rate meter. It can be further divided into two parts: heart rate calculation and system process control. The lower right part of Figure 2 is the output part. Including display output and communication output. The monitor outputs real-time heart rate, average heart rate, ECG waveform, alarm information and some setting information. The display used is Nokia5110 module. The communication output uses the UART serial port that comes with MSP430F5529, and outputs heart rate (immediate, average) and ECG data in a certain string format. If you connect the UART serial port to the USB to UART module, you can send data to the computer. If you connect the UART serial port to the Bluetooth serial port transparent transmission module, you can see the heart rate on Bluetooth devices such as mobile phones. This system uses a module based on TI's CC252541 low-power Bluetooth chip--HM-11 Bluetooth 4.0 BLE low-power Bluetooth serial port transparent transmission module produced by Jinan Huamao Company. And realize the display of instantaneous heart rate and average heart rate on the Android system.
图3、图4和图5中,一种低功耗心率监测仪输入部分包括,其一是人体I导联心电提取电路。其二是用户按键操作的输入,用于切换各个功能。人体I导联心电提取电路由五级构成。第一级是前置差分放大电路。进行前置放大,被处理后的信号具有低共模、低噪声、低漂移信号等性能。采用INA126差分放大器实现。第二级是截止频率为1Hz的高通滤波器。处理基线漂移。采用RC无源滤波实现。第三级是截止频率为100Hz的低通滤波器。处理高频干扰。采用二阶巴特沃斯有源滤波器实现,运放为精密运放OPA227。第四级是50Hz工频陷波器。尽可能减小工频干扰,这样才能在示波器上显现出可以辨别的心电波形。采用双T型无源滤波实现。第五级是最终放大与电平抬升电路。用一只OPA333单电源运放构成同相比例加法器,将心电信号最终放大到幅值1V左右,并和电源分压叠加,抬升到1~2V的区间。3.3V单电源运放同时起到保护ADC的作用。之后送入ADC模块。为了保证信号质量,采取右腿接地的方法,即将RL和系统的GND相连。系统设计输入阻抗40MΩ,逐级仿真测得25Hz时总放大倍数约为500倍。 In Fig. 3, Fig. 4 and Fig. 5, the input part of a heart rate monitor with low power consumption includes, one of which is a human body I lead ECG extraction circuit. The second is the input of the user's button operation, which is used to switch various functions. The human body I lead ECG extraction circuit consists of five stages. The first stage is a pre-differential amplifier circuit. Perform pre-amplification, and the processed signal has properties such as low common mode, low noise, and low drift signal. Implemented with INA126 differential amplifier. The second stage is a high-pass filter with a cutoff frequency of 1Hz. Dealing with baseline drift. It is realized by RC passive filtering. The third stage is a low-pass filter with a cutoff frequency of 100Hz. Deal with high-frequency interference. It is implemented by a second-order Butterworth active filter, and the op amp is a precision op amp OPA227. The fourth stage is a 50Hz power frequency notch filter. Minimize the power frequency interference as much as possible, so that the identifiable ECG waveform can be displayed on the oscilloscope. It is realized by double T-type passive filter. The fifth stage is the final amplification and level boosting circuit. An OPA333 single-supply op amp is used to form the same-phase proportional adder, and the ECG signal is finally amplified to an amplitude of about 1V, and superimposed with the power supply voltage division, and raised to the range of 1~2V. The 3.3V single-supply op amp also protects the ADC. Then send it to the ADC module. In order to ensure the signal quality, the method of grounding the right leg is adopted, that is, connecting RL to the GND of the system. The system design input impedance is 40MΩ, and the total magnification is about 500 times at 25Hz as measured by step-by-step simulation.
图6中展示了一种低功耗心率监测仪心率计算的过程。 Figure 6 shows the heart rate calculation process of a low-power heart rate monitor.
心率计算原理如下。 The heart rate calculation principle is as follows.
心电信号从ADC以500次/s的采样频率输入。 ECG signals are input from the ADC at a sampling frequency of 500 times/s.
之后进行50Hz平滑数字滤波。滤波方法是平滑滤波法,即将本次和前9次ADC采样结果的平均值作为本次的心电数据。以x表示ADC采样结果,y表示处理后得到的心电数据,则y(n)=[x(n)+x(n-1)+x(n-2)+x(n-3)+x(n-4)+x(n-5)+x(n-6)+x(n-7)+x(n-8)+x(n-9)]/10。 Afterwards, 50Hz smoothing digital filtering is performed. The filtering method is a smoothing filtering method, that is, the average value of the current and the previous 9 ADC sampling results is used as the current ECG data. Let x represent the ADC sampling result, and y represent the ECG data obtained after processing, then y(n)=[x(n)+x(n-1)+x(n-2)+x(n-3)+ x(n-4)+x(n-5)+x(n-6)+x(n-7)+x(n-8)+x(n-9)]/10.
再之后进行五点差分处理。以z表示差分结果,则有z(n)=2y(n)+y(n-1)-y(n-3)-2y(n-4)。 Then perform five-point difference processing. If the differential result is represented by z, then z(n)=2y(n)+y(n-1)-y(n-3)-2y(n-4).
将五点差分值与阈值m比较,每超过一次m即记为一次R波,以此作为判定心电R波的依据(但如果检测到的两个R波间隔过短(小于0.16s,即心率大于375次/分),就认为第二个R波是伪波,不计数)之后根据3次R波的间隔时间来计算即时心率,公式为即时心率=90000/(3次R波的时间差);根据一定时间(15s,30s,60s)之内的R波次数计算平均心率。 Compare the five-point differential value with the threshold m, and every time m is exceeded, it will be recorded as an R wave, which is used as the basis for judging the ECG R wave (but if the interval between the two detected R waves is too short (less than 0.16s, that is, If the heart rate is greater than 375 beats/min), the second R wave is considered to be a false wave and will not be counted) Then the real-time heart rate is calculated according to the interval time of the 3 R-waves, the formula is real-time heart rate=90000/(time difference of 3 R-waves ); Calculate the average heart rate based on the number of R waves within a certain period of time (15s, 30s, 60s).
阈值通过自学习算法获得,计算公式为阈值m=(2秒内心电数据最大值-2秒内心电数据最小值)*0.5。 The threshold is obtained through a self-learning algorithm, and the calculation formula is threshold m=(maximum value of ECG data within 2 seconds-minimum value of ECG data within 2 seconds)*0.5.
图7展示了系统的流程控制。系统流程控制是通过对MSP430F5529单片机编程来实现的。系统空闲时单片机进入LPM0低功耗模式以节省电力。通过1个主按键和2个辅助按键控制系统的功能模式,可选择心率与平均心率显示模式、心电波形模式、报警模式,并可以设定背光、报警灯和通信功能的开关。在任一模式下,心电信号的采集和心率的计算都是实时进行的。 Figure 7 shows the flow control of the system. System flow control is realized by programming the MSP430F5529 microcontroller. When the system is idle, the microcontroller enters the LPM0 low-power mode to save power. Control the function mode of the system through 1 main button and 2 auxiliary buttons, you can choose the display mode of heart rate and average heart rate, ECG waveform mode, alarm mode, and can set the switch of backlight, alarm light and communication function. In either mode, the collection of ECG signals and the calculation of heart rate are performed in real time.
图8展示的即为安卓系统上的心率显示,包括瞬时心率、15秒平均心率等功能。 Figure 8 shows the heart rate display on the Android system, including functions such as instantaneous heart rate and 15-second average heart rate.
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