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CN1041877A - General microcomputer fully-automatic extracorporeal reverse beating device - Google Patents

General microcomputer fully-automatic extracorporeal reverse beating device Download PDF

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Publication number
CN1041877A
CN1041877A CN 88105595 CN88105595A CN1041877A CN 1041877 A CN1041877 A CN 1041877A CN 88105595 CN88105595 CN 88105595 CN 88105595 A CN88105595 A CN 88105595A CN 1041877 A CN1041877 A CN 1041877A
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pulse wave
pressure pulse
counterpulsation
blood flow
circuit
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CN 88105595
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Chinese (zh)
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杨辰圆
蔡大卫
步阳敏
朱煜清
韩朔瞭
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Shanghai First Peoples Hospital
Shanghai Jiao Tong University
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Shanghai First Peoples Hospital
Shanghai Jiao Tong University
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Priority to CN 88105595 priority Critical patent/CN1041877A/en
Publication of CN1041877A publication Critical patent/CN1041877A/en
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Abstract

The present invention is a kind of computer-shape fully-automatic extracorporeal reverse beating device that grows up on former manual external counterpulsation apparatus basis, be characterized in adopting non-invasive pressure pulse wave signal to carry out closed loop feedback control, the diastolic wave starting point of temporo arterial pressure pulse wave is in the incisura place when guaranteeing counter fighting, to obtain desirable curative effect.On fluorescent screen, show electrocardiogram simultaneously, fill aerofluxus, pressure pulse wave and blood flow waveform and heart rate, premature beat counting, before counter the fighting and during counter fighting pressure pulse wave relaxing period and Syst area than and the relative blood flow value.

Description

使用通用微机的全自动体外反搏装置是治疗多种缺血性疾病的一种医疗仪器,属医疗仪器领域。A fully automatic external counterpulsation device using a general-purpose microcomputer is a medical instrument for treating various ischemic diseases, and belongs to the field of medical instruments.

现在治疗人的多种缺血性疾病如冠心病、脑动脉硬化症、视网膜中央动脉栓塞等疾病,国内都采用体外反搏方法,促使血流量在人体的疾病部位正常循环,达到治疗目的。国外大多数采用主动脉内囊反搏(创伤性)治疗缺血性疾病。国内有专利号为85200905的类似仪器,但这些仪器均属手控类型,即检出QRS波,用R波触发气阀的充气排气,充气的时间是按照耳垂脉搏波再配合手动调整,由于耳垂脉搏波无明显的切迹(即收缩期和舒张期的分界点),依靠手动调整体外反搏的方法,不能取得良好的疗效,而且由于不能确定最佳的体外反搏充气起始时间,将影响收缩期的正常射血,对人体有一定潜在的危险。Nowadays, in the treatment of various human ischemic diseases such as coronary heart disease, cerebral arteriosclerosis, and central retinal artery embolism, external counterpulsation is used in China to promote the normal circulation of blood flow in the diseased parts of the human body and achieve the purpose of treatment. Most foreign countries use intra-aortic sac counterpulsation (traumatic) to treat ischemic diseases. There are similar instruments with the patent number 85200905 in China, but these instruments are all of the manual type, that is, the QRS wave is detected, and the R wave is used to trigger the inflation and exhaust of the air valve. The inflation time is adjusted manually according to the earlobe pulse wave. There is no obvious notch in the earlobe pulse wave (that is, the dividing point between systole and diastole), and manual adjustment of external counterpulsation cannot achieve good curative effect. It will affect the normal blood ejection during the systole, and has certain potential danger to the human body.

本发明的目的是设计一种使用通用微机的全自动无创伤体外反搏控制系统,它检测出颞动脉(或者桡动脉、颈总动脉)脉搏波信号作为气阀充气的定时,再利用微型计算机实现反馈控制,以取得最佳的体外反搏时间,达到最好的治疗效果。The purpose of this invention is to design a fully automatic non-invasive external counterpulsation control system using a general-purpose microcomputer, which detects the pulse wave signal of the temporal artery (or radial artery, common carotid artery) as the timing of air valve inflation, and then uses the microcomputer Realize feedback control to obtain the best external counterpulsation time and achieve the best therapeutic effect.

本发明的优点是:充气时间、排气时间和进、排气压力实现全自动控制,而且确保充气时间精确。在8088微机上实现心电信号、开关阀信号、颞动脉压力脉搏波信号、颞动脉血流量信号的四线显示。还可进行心率计数、早搏计数、反搏计数、反搏前和反搏时颞动脉舒张期和收缩期面积之比,反搏前和反搏时颞动脉相对血流量值的数值显示以及反搏时间的倒数显示、治疗病种(肢体、心脏、眼)的图符显示,终末进气压力显示(0.3,0.4,0.5,0.6kg/cm2),控制装置具有记忆功能和冻结图象功能。The invention has the advantages that the full-automatic control of the inflation time, the exhaust time and the intake and exhaust pressures can be realized, and the accuracy of the inflation time can be ensured. The four-line display of ECG signal, switch valve signal, temporal artery pressure pulse wave signal and temporal artery blood flow signal is realized on 8088 microcomputer. It can also perform heart rate counting, premature beat counting, counterpulsation counting, the ratio of diastolic and systolic area of temporal artery before and during counterpulsation, numerical display of relative blood flow values of temporal artery before and during counterpulsation, and feedback The reciprocal display of stroke time, the icon display of treatment diseases (limbs, heart, eyes), the display of terminal air pressure (0.3, 0.4, 0.5, 0.6kg/cm 2 ), the control device has memory function and freeze image Function.

下面结合附图详细说明本实用新型的工作原理。The working principle of the utility model will be described in detail below in conjunction with the accompanying drawings.

图1是反搏控制系统方框图,图中从心电信号中检出R波,一路送心率采样电路,以便实时采样每个心动周期的信号,一路作为心率采样中断请求信号,经中断服务程序处理后算出一个初步的充气排气定时信号,该信号经开阀计时电路和关阀计时电路送到输出驱动电路,然后启动充气阀门的充气和排气,A/D转换电路分别采样反搏前、时颞动脉压力脉搏波信号,8088微型机依据反搏时颞动脉切点B的变化值和反搏前切点A的数值不断进行比较,生成一个不断调整充气时间的控制量,达到反馈闭环控制,A/D变换电路还采集反搏前、时血流量的变化数值,由微机的CRT进行数值显示,以便定量地确定反搏时的疗效。A/D采样发生器电路是用来保证微型机CRT显示的,并可不断刷新或冻结图象。时标发生电路产生标准的整机定时,提供屏幕数值显示并不断定时刷新屏幕。I/O译码电路是用来保证上述电路和8088微型机CPU协调工作的。Figure 1 is a block diagram of the counterpulsation control system. In the figure, the R wave is detected from the ECG signal, and one path is sent to the heart rate sampling circuit to sample the signal of each cardiac cycle in real time, and one path is used as a heart rate sampling interrupt request signal, which is processed by the interrupt service program Finally, a preliminary inflation and exhaust timing signal is calculated, and the signal is sent to the output drive circuit through the valve opening timing circuit and the valve closing timing circuit, and then the inflation and exhaust of the inflation valve are started, and the A/D conversion circuit respectively samples the Temporal artery pressure pulse wave signal, the 8088 microcomputer continuously compares the change value of temporal artery cut point B during counterpulsation with the value of cut point A before counterpulsation, and generates a control amount that continuously adjusts the inflation time to achieve feedback closed-loop control , The A/D conversion circuit also collects the change value of the blood flow before and during the counterpulsation, which is displayed by the CRT of the microcomputer, so as to quantitatively determine the curative effect of the counterpulsation. The A/D sampling generator circuit is used to ensure the CRT display of the microcomputer, and can continuously refresh or freeze the image. The time scale generating circuit generates standard machine timing, provides screen value display and constantly refreshes the screen. The I/O decoding circuit is used to ensure the coordinated work of the above circuit and 8088 microcomputer CPU.

图2是颞动脉压力脉搏波、耳垂脉搏波与心电图、心音图的时相关系。从图中可见,颞动脉压力脉搏波的切点A界线非常明显,而耳垂脉搏波无明显切点。颞动脉压力脉搏波切点A在心电图T波终止后(表示舒张期开始)位于第二心音S2(即主动脉办关闭声)处,由于颈总动脉、颞动脉、桡动脉离心脏距离不等,因此脉搏波切迹在时间上略有差异。Figure 2 is the time-phase relationship between temporal artery pressure pulse wave, earlobe pulse wave, electrocardiogram and phonocardiogram. It can be seen from the figure that the tangent point A boundary of the temporal artery pressure pulse wave is very obvious, but there is no obvious tangent point of the earlobe pulse wave. The tangent point A of the temporal artery pressure pulse wave is located at the second heart sound S 2 (that is, the closing sound of the aorta) after the termination of the T wave of the electrocardiogram (indicating the start of the diastolic period), because the distances from the common carotid artery, temporal artery, and radial artery to the heart are not equal , so the pulse wave traces are slightly different in time.

图3是体外反搏前和反搏时耳垂脉搏波和颞动脉脉搏波的变化情况,由图可见,反搏开始时四分钟,颞动脉压力脉搏波的舒张波起始点B,在时间上与反搏前压力脉搏波切点A重叠,舒张波上升并超过收缩波达到最佳效果。反搏五十五分钟时其波形和波幅无明显变化,受呼吸影响小。耳垂脉搏波虽然在一定程度上也能反映反搏效果,但无法确定耳垂脉搏波起始升高点的时相,在反搏一小时后波形和波幅变化较大。Figure 3 shows the changes of the earlobe pulse wave and temporal artery pulse wave before and during external counterpulsation. It can be seen from the figure that four minutes after the start of the counterpulsation, the diastolic wave starting point B of the temporal artery pressure pulse wave is different in time from Before counterpulsation, the tangent point A of the pressure pulse wave overlaps, and the diastolic wave rises and exceeds the systolic wave to achieve the best effect. After 55 minutes of counterpulsation, there is no obvious change in its waveform and amplitude, and it is less affected by breathing. Although the earlobe pulse wave can also reflect the counterpulsation effect to a certain extent, the phase of the initial rising point of the earlobe pulse wave cannot be determined, and the waveform and amplitude change greatly after one hour of counterpulsation.

图4是实现通用微机全自动体外反搏系统的程序流程图,图中初始化参数的设置是设置脑病类的参数,即程序启动后自动选择脑病类患者进行反搏治疗。中断向量的设置是用于三个中断服务程序,以便实时完成电磁阀门开关定时、图象显示和数字化时钟的控制等功能。在系统开始为病人进行反搏治疗前,系统都要生成数据记录格式,以记录反搏过程中病人的各种病情参数,便于医生及时了解和掌握患者病情。Figure 4 is a program flow chart for realizing a general-purpose microcomputer automatic external counterpulsation system. In the figure, the initialization parameter setting is to set the parameters of encephalopathy, that is, after the program is started, patients with encephalopathy are automatically selected for counterpulsation treatment. The setting of the interrupt vector is used for three interrupt service routines, in order to complete the functions of the solenoid valve switch timing, image display and digital clock control in real time. Before the system starts counterpulsation treatment for the patient, the system must generate a data record format to record various parameters of the patient's condition during the counterpulsation process, so that the doctor can understand and grasp the patient's condition in time.

本发明使用超声流量计从颞动脉(或桡动脉、颈总动脉)处检测反搏前、时的血流量在8088微机的CRT上进行数值显示,作为体外反搏疗效的标准。The present invention uses an ultrasonic flowmeter to detect the blood flow before and during counterpulsation from the temporal artery (or radial artery, common carotid artery), and displays the numerical value on the CRT of the 8088 microcomputer as a standard for the curative effect of external counterpulsation.

本发明的反搏控制框图1做成硬件板,作为8088微型机的扩充板插在8088机箱内。输出驱动、充、排气的电磁阀装置和气囊是已有技术。The counterpulsation control block diagram 1 of the present invention is made into a hardware board, which is inserted in the 8088 case as an expansion board of the 8088 microcomputer. The electromagnetic valve device and the air bag of output driving, filling and exhausting are prior art.

本发明作为一种无创伤性的机械辅助循环装置,能够治疗多种缺血性疾病如冠心病,脑动脉硬化症、脑血栓、脑梗塞、视网膜中央动脉栓塞、缺血性视神经萎缩、肢体缺血性疾病等,由于本装置完全自动控制,所以除了适用于医疗机构外,还适用于家庭保健和康复方面。As a non-invasive mechanical assisted circulation device, the present invention can treat various ischemic diseases such as coronary heart disease, cerebral arteriosclerosis, cerebral thrombosis, cerebral infarction, central retinal artery embolism, ischemic optic atrophy, limb defect, etc. Blood diseases, etc., because the device is fully automatic control, so in addition to being suitable for medical institutions, it is also suitable for family health care and rehabilitation.

Claims (2)

1, a kind of by bed body, the pump housing, the mini-computer that comprise air bag and valve body and detect electrocardiosignal and fully-automatic extracorporeal reverse beating device that the blood flow instrument is formed, it is characterized in that control circuit with microcomputer interface by A/D changer 4, R ripple output circuit 5, heart rate sample circuit 6, I/O decoder 7, time mark generator 8, A/D sample rate generator 9, drive valve pass valve timing circuit 10,11 and form.
2, a kind of fully-automatic extracorporeal reverse beating closed loop is returned the feedback control device, it is characterized in that the pressure pulse wave signal 1 imported as control signal with return feedback signal, and be before the noinvasive triage is surveyed external counterpulsation, the time human body temporo tremulous pulse (or radial artery, common carotid artery) pressure pulse wave signal obtain.
CN 88105595 1988-10-21 1988-10-21 General microcomputer fully-automatic extracorporeal reverse beating device Pending CN1041877A (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006114055A1 (en) * 2005-04-25 2006-11-02 The First Affiliated Hospital, Sun Yat-Sen University Health and rehabilitation therapy system for blood vessel
CN102119908A (en) * 2011-03-21 2011-07-13 中国人民解放军军事医学科学院卫生装备研究所 Closed-loop external chest compression system
CN102813569A (en) * 2012-09-10 2012-12-12 广州赞德利医疗科技有限公司 Pulse collecting type negative pressure rehabilitation therapy apparatus for controlling man erectile dysfunction (ED) functions
CN101835447B (en) * 2007-09-21 2013-07-17 皇家飞利浦电子股份有限公司 Cpr monitoring and reporting system
CN113018135A (en) * 2021-02-24 2021-06-25 山东交通学院 External counterpulsation cooperative control system and method
WO2022247695A1 (en) * 2021-05-24 2022-12-01 中山大学附属第一医院 Portable apparatus for improving vascular endothelial function
CN115624691A (en) * 2022-09-26 2023-01-20 安徽通灵仿生科技有限公司 Double closed-loop control method, system and storage medium for external counterpulsation
CN115645734A (en) * 2022-09-26 2023-01-31 安徽通灵仿生科技有限公司 Method, system and storage medium for evaluating effect of external counterpulsation on coronary heart disease treatment
CN117379683A (en) * 2023-12-12 2024-01-12 苏州晟智医疗科技有限公司 Counterpulsation auxiliary device, computing device, storage medium and counterpulsation system
CN118415864A (en) * 2024-04-26 2024-08-02 深圳市艾利特医疗科技有限公司 Data analysis and monitoring method and system of external counterpulsation device

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006114055A1 (en) * 2005-04-25 2006-11-02 The First Affiliated Hospital, Sun Yat-Sen University Health and rehabilitation therapy system for blood vessel
CN101835447B (en) * 2007-09-21 2013-07-17 皇家飞利浦电子股份有限公司 Cpr monitoring and reporting system
CN102119908A (en) * 2011-03-21 2011-07-13 中国人民解放军军事医学科学院卫生装备研究所 Closed-loop external chest compression system
CN102119908B (en) * 2011-03-21 2013-06-05 中国人民解放军军事医学科学院卫生装备研究所 Closed-loop external chest compression system
CN102813569A (en) * 2012-09-10 2012-12-12 广州赞德利医疗科技有限公司 Pulse collecting type negative pressure rehabilitation therapy apparatus for controlling man erectile dysfunction (ED) functions
CN113018135A (en) * 2021-02-24 2021-06-25 山东交通学院 External counterpulsation cooperative control system and method
WO2022247695A1 (en) * 2021-05-24 2022-12-01 中山大学附属第一医院 Portable apparatus for improving vascular endothelial function
CN115624691A (en) * 2022-09-26 2023-01-20 安徽通灵仿生科技有限公司 Double closed-loop control method, system and storage medium for external counterpulsation
CN115645734A (en) * 2022-09-26 2023-01-31 安徽通灵仿生科技有限公司 Method, system and storage medium for evaluating effect of external counterpulsation on coronary heart disease treatment
CN117379683A (en) * 2023-12-12 2024-01-12 苏州晟智医疗科技有限公司 Counterpulsation auxiliary device, computing device, storage medium and counterpulsation system
CN117379683B (en) * 2023-12-12 2024-02-27 苏州晟智医疗科技有限公司 Counterpulsation assisting device, computing equipment, storage medium and counterpulsation system
CN118415864A (en) * 2024-04-26 2024-08-02 深圳市艾利特医疗科技有限公司 Data analysis and monitoring method and system of external counterpulsation device

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