CN1041277C - Quick action injection - Google Patents
Quick action injection Download PDFInfo
- Publication number
- CN1041277C CN1041277C CN93100677A CN93100677A CN1041277C CN 1041277 C CN1041277 C CN 1041277C CN 93100677 A CN93100677 A CN 93100677A CN 93100677 A CN93100677 A CN 93100677A CN 1041277 C CN1041277 C CN 1041277C
- Authority
- CN
- China
- Prior art keywords
- injection
- quick action
- present
- action injection
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000002347 injection Methods 0.000 title claims abstract description 24
- 239000007924 injection Substances 0.000 title claims abstract description 24
- 239000003814 drug Substances 0.000 claims abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000008215 water for injection Substances 0.000 claims abstract description 6
- 229940079593 drug Drugs 0.000 claims abstract description 4
- OSASVXMJTNOKOY-UHFFFAOYSA-N chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 5
- 241000628997 Flos Species 0.000 claims description 4
- 239000006286 aqueous extract Substances 0.000 claims description 4
- 229960004926 chlorobutanol Drugs 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 2
- 201000010099 disease Diseases 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract description 5
- 239000000243 solution Substances 0.000 abstract description 4
- 230000036737 immune function Effects 0.000 abstract description 2
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 241001148783 Davallia mariesii Species 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000001467 acupuncture Methods 0.000 description 3
- 210000003423 ankle Anatomy 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 210000001513 elbow Anatomy 0.000 description 2
- 210000000629 knee joint Anatomy 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000000707 wrist Anatomy 0.000 description 2
- 239000001606 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one Substances 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 229920000875 Dissolving pulp Polymers 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 229920001131 Pulp (paper) Polymers 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940124599 anti-inflammatory drug Drugs 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 210000004247 hand Anatomy 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- DFPMSGMNTNDNHN-ZPHOTFPESA-N naringin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](OC=2C=C3O[C@@H](CC(=O)C3=C(O)C=2)C=2C=CC(O)=CC=2)O[C@H](CO)[C@@H](O)[C@@H]1O DFPMSGMNTNDNHN-ZPHOTFPESA-N 0.000 description 1
- 229940052490 naringin Drugs 0.000 description 1
- 229930019673 naringin Natural products 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002832 shoulder Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a quick action injection which is characterized in that An extracting solution which is prepared with safflower caulis impatientis and davallia mariesii moore according to a proportion of one to one is added with auxiliary components of trichlorbutanolum and water for injection to prepare the quick action injection. Per milliliter of the quick action injection contains 2.5g of crude drugs, and the daily dosage of the quick action injection is 6 milliliters. The present invention not only has a higher effectiveness ratio (96.77%) to the treatment of rheumatoid arthritis, but also has a certain cure rate (11.69%). The present invention not only has no toxic side effects, but also can enhance immune functions of human bodies. Thus, the quick action injection has the advantage of treatment of both manifestation and root causes of diseases.
Description
The present invention relates to a kind of Chinese medicine preparation quick action injection for the treatment of rheumatoid arthritis.
Rheumatoid arthritis, be to refer to infringement, toe, wrist, ankle, elbow, the chronic property the done general disease of sending out repeatedly in all joints such as knee joint, belong to Chinese medical ' arthralgia syndrome ' category, be called " rheumatoid arthritis " or " rheumatism involving the bone ", patient is in the majority with person between twenty and fifty, first patient's hands, little redness and swelling of joints such as foot, pain, distortion, then develop into shoulder, hip, elbow, knee joint, wrist, big joint such as ankle, patient's whole body is stiff when serious, the forfeiture self care ability, this disease is a kind of pertinacious disease, China 500-800 ten thousand patients, the past adopts the doctor trained in Western medicine anti-inflammatory drug to treat always at present, but because side effect is big, patient is difficult to adhere to taking medicine, and curative effect is also not obvious.
The purpose of this invention is to provide a kind of Chinese medicine preparation quick action injection for the treatment of above-mentioned disease.
The objective of the invention is to adopt following proposal to finish: press in the aqueous extract of preparation in 1: 1 at Flos Carthami Caulis Impatientis and Rhizoma Drynariae, it is formulated to add adjuvant chlorobutanol and water for injection again, every milliliter of this injection contains crude drug 1.25 grams, Coming-of-Age Day consumption be 6 milliliters.Injection of the present invention is suitable for acupoint injection therapy most, selects 3-6 acupuncture point for use at every turn, 6 milliliters of each consumptions, medicinal liquid 0.5-0.8 milliliter is injected at each acupuncture point, the next day once, be for ten times a course of treatment, three rest course of treatment 2-4 continue injection after week again.
The present invention once carried out observation of curative effect to 650 examples, and clinical complete more 76 examples account for 11.65%; Produce effects 204 examples account for 31.38%; 349 examples that take a turn for the better account for 53.69%; Invalid 21 examples account for 3.2%.Therefore, the present invention not only has higher effective rate (96.77%) to the treatment of rheumatoid arthritis, and certain cure rate (11.69%) is arranged, and not only has no side effect, and also can strengthen the immunologic function of human body, treating both the principal and secondary aspects of a disease.
Below in conjunction with embodiment the present invention is further described.
Selection has strict demand to medicine in the present invention, one, Caulis Impatientis (Impatiensbalsamyna) mainly originates in ground such as China Anhui, Jiangsu, Hebei, Jiangxi, and is common for spending Caulis Impatientis or blue flower Caulis Impatientis in vain, and the present invention must use the Flos Carthami Caulis Impatientis.Its two, Rhizoma Drynariae is distributed in ground such as China Guangxi, Guangdong, Liaoning, Zhejiang, Hubei, Haizhou, the Rhizoma Drynariae that the present invention only selects for use Haizhou to produce.
The manufacture method of " quick action injection ":
Prescription: Rhizoma Drynariae, Caulis Impatientis aqueous extract 500ml
Chlorobutanol 6.4g
Water for injection is an amount of
Make the 1500ml aseptic aqueous solution.
Method for making:
Get Rhizoma Drynariae, Caulis Impatientis extracting solution, paper pulp filtering to clear and bright, add chlorobutanol, make abundant mixing dissolving after, adjust to requirement with water for injection, adjust pH value, fine straining, embedding, sterilization, lettering, packing.
Attached: the preparation method of Rhizoma Drynariae, Caulis Impatientis aqueous extract:
Prescription: Rhizoma Drynariae 1500g
Flos Carthami Caulis Impatientis 1500g
Method for making: get above-mentioned two Rui's decoction pieces, decoct with water secondary, collecting decoction, filter, concentrate, concentrated solution is with Ethanol Treatment three times, remove the molten thing of pure fourth each the separation, alcoholic solution reclaims ethanol, and concentrates or extractum, adds injection water 700ml, it is clear and bright that dissolving pulp is filtered to, be adjusted to 800ml with water for injection, measure naringin content, sterilization, cold preservation, be made for injection and use.
After the present invention makes the injection injection, 2 milliliters of per ampoules, every milliliter contains crude drug 1.25 grams.
Year surplus " quick action injection " clinical use 20, codeposition tires out tens thousand of routine case histories, enjoy certain reputation at home and abroad, obtained province, city-level prize for the achveivement in science and technology once for three times, participate in international meeting four times, and read out paper in conference, its paper is interpreted into English, day, method three state's literal, income conference paper compilation, Ceng Sanci publishes thesis on country-level publication and provincial, and municipal level publication, this injection total effective rate reaches 96.7%, and clinical cure rate reaches 11.69%, does not still have the report of clinical cure in similar medicine.
1987 the 6th phase page 1 " acupoint injection therapy treatment arthromyodynia 650 routine observation of curative effect " of the treatment case of " quick action injection " (referring to adnexa 1) " Chinese acupuncture and moxibustion ".
Claims (1)
1, a kind of quick action injection, be prepared from by Caulis Impatientis and Rhizoma Drynariae, it is characterized in that: add adjuvant chlorobutanol and water for injection at Flos Carthami Caulis Impatientis and Rhizoma Drynariae again in the aqueous extract by preparation in 1: 1, formulated, this injection contains crude drug 1.25 grams for every milliliter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93100677A CN1041277C (en) | 1993-02-01 | 1993-02-01 | Quick action injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93100677A CN1041277C (en) | 1993-02-01 | 1993-02-01 | Quick action injection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1090496A CN1090496A (en) | 1994-08-10 |
| CN1041277C true CN1041277C (en) | 1998-12-23 |
Family
ID=4983176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93100677A Expired - Fee Related CN1041277C (en) | 1993-02-01 | 1993-02-01 | Quick action injection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1041277C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099873C (en) * | 1999-04-23 | 2003-01-29 | 姜进华 | The application of yangyizi as a medicine for the preparation of osteoarthritis |
| CN103494909B (en) * | 2013-09-25 | 2016-01-20 | 赵新刚 | A kind of Chinese medicine composition for the treatment of comminuted bone injury |
| CN120732941B (en) * | 2025-08-29 | 2026-01-30 | 贵州中医药大学第二附属医院 | Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86102004A (en) * | 1986-03-26 | 1987-10-14 | 北京市崇文区中医医院 | The production method that " chases after wind speed " |
-
1993
- 1993-02-01 CN CN93100677A patent/CN1041277C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86102004A (en) * | 1986-03-26 | 1987-10-14 | 北京市崇文区中医医院 | The production method that " chases after wind speed " |
Non-Patent Citations (1)
| Title |
|---|
| 《中药药剂学》上海科学技术出版社，1986年11月第一版 1986.11.1 曹春林等，上海科学技术出版社 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1090496A (en) | 1994-08-10 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C53 | Correction of patent for invention or patent application | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: PATENTEE; FROM: TIANTAN TRADITIONAL CHINESE MEDICINE HOSPITAL BEIJING TO: BEIJING CHONGWENDISTRICT CHINESE MEDICINE HOSPITAL |
|
| CP01 | Change in the name or title of a patent holder |
Patentee after: Chongwen District Traditional Chinese Medical Hospital, Beijing Patentee before: Tiantan Traditional Chinese Medicine Hospital Beijing |
|
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |