CL2019002446A1 - Dropropizina en combinación con ambroxol en la forma farmacéutica de jarabe y tabletas. - Google Patents
Dropropizina en combinación con ambroxol en la forma farmacéutica de jarabe y tabletas.Info
- Publication number
- CL2019002446A1 CL2019002446A1 CL2019002446A CL2019002446A CL2019002446A1 CL 2019002446 A1 CL2019002446 A1 CL 2019002446A1 CL 2019002446 A CL2019002446 A CL 2019002446A CL 2019002446 A CL2019002446 A CL 2019002446A CL 2019002446 A1 CL2019002446 A1 CL 2019002446A1
- Authority
- CL
- Chile
- Prior art keywords
- dropropizine
- ambroxol
- combination
- syrup
- tablets
- Prior art date
Links
- PTVWPYVOOKLBCG-UHFFFAOYSA-N 3-(4-phenyl-1-piperazinyl)propane-1,2-diol Chemical compound C1CN(CC(O)CO)CCN1C1=CC=CC=C1 PTVWPYVOOKLBCG-UHFFFAOYSA-N 0.000 title abstract 2
- JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical compound NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 title abstract 2
- 229960005174 ambroxol Drugs 0.000 title abstract 2
- 229960004722 dropropizine Drugs 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 title 1
- 239000006188 syrup Substances 0.000 title 1
- 235000020357 syrup Nutrition 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A UNA COMBINACIÓN FARMACÉUTICA DE AMBROXOL O UNA SAL FARMACÉUTICAMENTE ACEPTABLE DEL MISMO Y DROPROPIZINA. ASIMISMO, SE REFIERE A UNA COMPOSICIÓN FARMACÉUTICA, PREFERENTEMENTE EN UNA FORMA DE ADMINISTRACIÓN ORAL, QUE CONTIENE DICHOS INGREDIENTES ACTIVOS, JUNTO CON UNO O MÁS ADITIVOS FARMACÉUTICAMENTE ACEPTABLES. LA INVENCIÓN TAMBIÉN SE REFIERE A LOS PROCESOS DE PREPARACIÓN Y LOS PROCESOS DE USO DE LA COMBINACIÓN FARMACÉUTICA O LA COMPOSICIÓN FARMACÉUTICA DE LA PRESENTE INVENCIÓN.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2017014725A MX2017014725A (es) | 2017-11-16 | 2017-11-16 | Dropropizina en combinacion con ambroxol en la forma farmaceutica de jarabe y tabletas. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2019002446A1 true CL2019002446A1 (es) | 2019-12-13 |
Family
ID=66538528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2019002446A CL2019002446A1 (es) | 2017-11-16 | 2019-08-26 | Dropropizina en combinación con ambroxol en la forma farmacéutica de jarabe y tabletas. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20210128496A1 (es) |
| CL (1) | CL2019002446A1 (es) |
| CO (1) | CO2019013645A2 (es) |
| CR (1) | CR20190401A (es) |
| DO (1) | DOP2019000233A (es) |
| MX (1) | MX2017014725A (es) |
| NI (1) | NI201900084A (es) |
| PE (1) | PE20191820A1 (es) |
| WO (1) | WO2019097309A1 (es) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1203721B (it) * | 1983-12-29 | 1989-02-23 | Dompe Farmaceutici Spa | Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono |
| DE19933148A1 (de) * | 1999-07-20 | 2001-01-25 | Boehringer Ingelheim Int | Ambroxolhaltige Lutschtablette |
| KR101915056B1 (ko) * | 2012-04-10 | 2018-11-07 | 한미약품 주식회사 | 암브록솔, 레보드로프로피진 및 완충제를 포함하는 경구용 액상 제제 및 이의 제조방법 |
-
2017
- 2017-11-16 MX MX2017014725A patent/MX2017014725A/es unknown
-
2018
- 2018-04-19 CR CR20190401A patent/CR20190401A/es unknown
- 2018-04-19 PE PE2019002014A patent/PE20191820A1/es unknown
- 2018-04-19 WO PCT/IB2018/052699 patent/WO2019097309A1/es not_active Ceased
- 2018-04-19 US US16/497,269 patent/US20210128496A1/en not_active Abandoned
-
2019
- 2019-07-31 NI NI201900084A patent/NI201900084A/es unknown
- 2019-08-26 CL CL2019002446A patent/CL2019002446A1/es unknown
- 2019-09-12 DO DO2019000233A patent/DOP2019000233A/es unknown
- 2019-12-03 CO CONC2019/0013645A patent/CO2019013645A2/es unknown
-
2023
- 2023-11-17 US US18/512,349 patent/US20240082176A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NI201900084A (es) | 2020-04-02 |
| US20240082176A1 (en) | 2024-03-14 |
| PE20191820A1 (es) | 2019-12-27 |
| CO2019013645A2 (es) | 2020-01-17 |
| CR20190401A (es) | 2019-11-18 |
| DOP2019000233A (es) | 2019-12-15 |
| MX2017014725A (es) | 2019-05-17 |
| WO2019097309A1 (es) | 2019-05-23 |
| US20210128496A1 (en) | 2021-05-06 |
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