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CL2019002323A1 - Anticuerpo dirigido a il-13ra2 y su uso. - Google Patents

Anticuerpo dirigido a il-13ra2 y su uso.

Info

Publication number
CL2019002323A1
CL2019002323A1 CL2019002323A CL2019002323A CL2019002323A1 CL 2019002323 A1 CL2019002323 A1 CL 2019002323A1 CL 2019002323 A CL2019002323 A CL 2019002323A CL 2019002323 A CL2019002323 A CL 2019002323A CL 2019002323 A1 CL2019002323 A1 CL 2019002323A1
Authority
CL
Chile
Prior art keywords
antibody
medication
tumor
diagnosis
manufacture
Prior art date
Application number
CL2019002323A
Other languages
English (en)
Inventor
Peng Wang
Huamao Wang
Original Assignee
Carsgen Therapeutics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carsgen Therapeutics Co Ltd filed Critical Carsgen Therapeutics Co Ltd
Publication of CL2019002323A1 publication Critical patent/CL2019002323A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/41—Vertebrate antigens
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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Abstract

SE PROPORCIONA UN ANTICUERPO QUE RECONOCE ESPECÍFICAMENTE EL IL-13RA2, QUE SE PUEDE UTILIZAR EN LA FABRICACIÓN DE UN MEDICAMENTO ANTITUMORAL ESPECÍFICO, ASÍ COMO DE UN MEDICAMENTO PARA EL DIAGNÓSTICO DE UN TUMOR.
CL2019002323A 2017-02-17 2019-08-16 Anticuerpo dirigido a il-13ra2 y su uso. CL2019002323A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201710087299 2017-02-17
CN201810079015.XA CN108456250B (zh) 2017-02-17 2018-01-26 靶向il-13ra2的抗体及其应用

Publications (1)

Publication Number Publication Date
CL2019002323A1 true CL2019002323A1 (es) 2019-12-06

Family

ID=63239077

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2019002323A CL2019002323A1 (es) 2017-02-17 2019-08-16 Anticuerpo dirigido a il-13ra2 y su uso.
CL2021003422A CL2021003422A1 (es) 2017-02-17 2021-12-20 Anticuerpos anti il-13ra2 y usos de los mismos (divisional 201902323).

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2021003422A CL2021003422A1 (es) 2017-02-17 2021-12-20 Anticuerpos anti il-13ra2 y usos de los mismos (divisional 201902323).

Country Status (14)

Country Link
US (1) US11530270B2 (es)
EP (1) EP3594241A4 (es)
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