CL2019000209A1 - Formulación novedosa administrable por la vía oral. - Google Patents
Formulación novedosa administrable por la vía oral.Info
- Publication number
- CL2019000209A1 CL2019000209A1 CL2019000209A CL2019000209A CL2019000209A1 CL 2019000209 A1 CL2019000209 A1 CL 2019000209A1 CL 2019000209 A CL2019000209 A CL 2019000209A CL 2019000209 A CL2019000209 A CL 2019000209A CL 2019000209 A1 CL2019000209 A1 CL 2019000209A1
- Authority
- CL
- Chile
- Prior art keywords
- orally administrable
- administrable formulation
- pharmaceutical agent
- particles
- novel orally
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/348—Cannabaceae
- A61K36/3482—Cannabis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Confectionery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
FORMULACIÓN ADMINISTRABLE ORALMENTE CONSISTENTE EN UNA GOMA DE MASCAR QUE COMPRENDE UNA BASE DE GOMA FARMACÉUTICAMENTE ACEPTABLE Y PARTÍCULAS DE UN AGENTE FARMACÉUTICO QUE VARÍAN EN TAMAÑO DESDE APROXIMADAMENTE 50 HASTA APROXIMADAMENTE 2000 µM EN EL QUE LA FORMULACIÓN COMPRENDE APROXIMADAMENTE 0,5-30% EN PESO DE LAS PARTÍCULAS DE AGENTE FARMACÉUTICO. TAMBIÉN SE PROPORCIONA UNA FORMULACIÓN LÍQUIDA QUE COMPRENDE PARTÍCULAS DE UN AGENTE FARMACÉUTICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/222,019 US9833408B1 (en) | 2016-07-28 | 2016-07-28 | Orally administrable formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2019000209A1 true CL2019000209A1 (es) | 2019-09-27 |
Family
ID=60451833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2019000209A CL2019000209A1 (es) | 2016-07-28 | 2019-01-25 | Formulación novedosa administrable por la vía oral. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9833408B1 (es) |
| EP (2) | EP3490539B1 (es) |
| JP (2) | JP7050777B2 (es) |
| AU (2) | AU2017301239B2 (es) |
| BR (2) | BR122020007418B1 (es) |
| CL (1) | CL2019000209A1 (es) |
| CO (1) | CO2019001895A2 (es) |
| CU (1) | CU20190005A7 (es) |
| IL (1) | IL264484A (es) |
| MX (1) | MX383529B (es) |
| PE (1) | PE20190738A1 (es) |
| WO (1) | WO2018018152A1 (es) |
| ZA (2) | ZA201901116B (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9833408B1 (en) * | 2016-07-28 | 2017-12-05 | Allen Greenspoon | Orally administrable formulation |
| US10239808B1 (en) | 2016-12-07 | 2019-03-26 | Canopy Holdings, LLC | Cannabis extracts |
| US11699166B2 (en) | 2017-10-09 | 2023-07-11 | American Express Travel Related Services Company, Inc. | Multi-merchant loyalty point partnership |
| US11449887B2 (en) | 2017-10-09 | 2022-09-20 | American Express Travel Related Services Company, Inc. | Systems and methods for loyalty point distribution |
| US11397962B2 (en) | 2017-10-09 | 2022-07-26 | American Express Travel Related Services Company, Inc. | Loyalty point distributions using a decentralized loyalty ID |
| CA3089994A1 (en) | 2018-01-31 | 2019-08-08 | Canopy Holdings, LLC | Hemp powder |
| US11951086B2 (en) * | 2018-04-03 | 2024-04-09 | Pure Green Pharmaceuticals, Inc. | Tablet or composition having n-acyl ethanolamine and cannabinoid |
| EP3549579A1 (en) * | 2018-04-03 | 2019-10-09 | Sanofi Winthrop Industrie | Oral gum formulation and fabrication process thereof |
| US11728995B2 (en) | 2018-04-09 | 2023-08-15 | American Express Travel Related Services Company, Inc. | Reward point transfers using blockchain |
| US10783545B2 (en) | 2018-04-19 | 2020-09-22 | American Express Travel Related Services Company, Inc. | Reward point redemption for cryptocurrency |
| WO2020061584A1 (en) * | 2018-09-21 | 2020-03-26 | Msb Holdings, Inc. | Taste-masked dosage forms |
| US11040932B2 (en) | 2018-10-10 | 2021-06-22 | Treehouse Biotech, Inc. | Synthesis of cannabigerol |
| US11166910B2 (en) | 2019-01-25 | 2021-11-09 | Nordiccan A/S | Cannabinoid chewing gum with sugar alcohols |
| WO2020151793A1 (en) * | 2019-01-25 | 2020-07-30 | Medcan Pharma A/S | Chewing gum with improved delivery of cannabinoids |
| WO2020151791A1 (en) * | 2019-01-25 | 2020-07-30 | Medcan Pharma A/S | Cannabinoid chewing gum with sugar alcohols |
| WO2020151789A1 (en) * | 2019-01-25 | 2020-07-30 | Medcan Pharma A/S | Cannabinoid chewing gum with polyvinyl acetate elastomer plasticizers |
| US11154496B2 (en) * | 2019-01-25 | 2021-10-26 | Nordiccan A/S | Cannabinoid chewing gum with polyvinyl acetate elastomer plasticizers |
| US11013685B2 (en) * | 2019-01-25 | 2021-05-25 | Nordiccan A/S | Cannabinoid chewing gum with improved release of cannabinoids |
| AU2019424547B2 (en) * | 2019-01-25 | 2023-06-22 | Nordiccan A/S | Cannabinoid chewing gum with improved release of cannabinoids |
| US11406593B2 (en) | 2019-01-25 | 2022-08-09 | Nordiccan A/S | Cannabinoid chewing gum with high intensity sweeteners |
| US11191720B2 (en) | 2019-01-25 | 2021-12-07 | Nordiccan A/S | Chewing gum with improved delivery of cannabinoids |
| WO2020151790A1 (en) * | 2019-01-25 | 2020-07-30 | Medcan Pharma A/S | Cannabinoid chewing gum with high intensity sweeteners |
| US11253473B2 (en) * | 2019-03-01 | 2022-02-22 | Nordiccan A/S | Method of producing tableted cannabinoid chewing gum |
| US10799450B2 (en) | 2019-03-01 | 2020-10-13 | Medcan Pharma A/S | Tableted cannabinoid chewing gum with layered structure |
| US11471405B2 (en) | 2019-03-01 | 2022-10-18 | Nordiccan A/S | Tableted chewing gum with enhanced delivery of cannabinoids |
| US10933017B2 (en) | 2019-03-01 | 2021-03-02 | Nordiccan A/S | Tableted cannabinoid chewing gum with polyvinyl acetate elastomer plasticizers |
| US11331309B2 (en) * | 2019-06-05 | 2022-05-17 | Cure Pharmaceutical Holding Corp. | Methods and compositions for improving sleep |
| US20220273558A1 (en) * | 2019-08-02 | 2022-09-01 | Advanced Female Technologies Llc | Chewing Gum Compositions Containing Cannabinoids |
| US20220378677A1 (en) * | 2019-10-31 | 2022-12-01 | M. Mustix Ltd | Treatment of tooth decay using a chewing gum composition comprising cannabinoids |
| AU2020403651A1 (en) | 2019-12-09 | 2022-07-07 | Nicoventures Trading Limited | Oral product comprising a cannabinoid |
| WO2021116825A1 (en) * | 2019-12-09 | 2021-06-17 | Nicoventures Trading Limited | Oral product |
| US11363834B2 (en) | 2020-10-01 | 2022-06-21 | Tobacco Technology, Inc. | Shisha, heat-not-burn, or combustion casing, product, and method of making the same |
| US11058142B1 (en) | 2020-10-01 | 2021-07-13 | Tobacco Technology, Inc. | Shisha, heat-not-burn, or combustion casing with active ingredient, product and casing with active ingredient, and method of making the same |
| EP4243796A4 (en) * | 2020-11-16 | 2025-01-22 | Orcosa Inc. | IMPROVED USE OF CANNABINOIDS IN THE TREATMENT OF EPILEPSY |
| US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
| US11839602B2 (en) | 2020-11-25 | 2023-12-12 | Nicoventures Trading Limited | Oral cannabinoid product with lipid component |
| WO2023272335A1 (en) * | 2021-06-30 | 2023-01-05 | Emyria | Cannabidiol formulation comprising a matrix pellet forming excipient |
| CA3234805A1 (en) * | 2021-10-11 | 2023-04-20 | C. Russell Thomas | Biphasic compositions comprising one or both of carbonate and phosphate |
| WO2025043046A1 (en) * | 2023-08-22 | 2025-02-27 | GlycosBio, INC. | Latex-compatible oil-based compositions |
| DK202330231A1 (en) * | 2023-09-27 | 2025-04-10 | Fertin Pharma As | Cannabidiol for alleviating xerostomia |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816265A (en) * | 1986-12-23 | 1989-03-28 | Warner-Lambert Company | Sweetener delivery systems containing polyvinyl acetate |
| DK505588D0 (da) * | 1988-02-26 | 1988-09-09 | Jesper Hamburger | Middel og anvendelse af samme |
| US6132762A (en) * | 1997-05-05 | 2000-10-17 | Cristobal; Walter | Transcutaneous application of marijuana |
| US7648696B2 (en) * | 1999-08-20 | 2010-01-19 | Unimed Pharmaceuticals, Llc | Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent |
| MXPA02008778A (es) * | 2000-03-09 | 2005-06-20 | Gw Pharma Ltd | Composiciones farmaceuticas. |
| JP5009482B2 (ja) * | 2000-12-07 | 2012-08-22 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 酸に不安定な活性成分を含有する懸濁液の形の製薬製剤 |
| CA2438097C (en) * | 2001-02-14 | 2006-04-25 | Gw Pharma Limited | Cannabinoids pharmaceutical formulations |
| DE10109763A1 (de) | 2001-02-28 | 2002-09-05 | Gruenenthal Gmbh | Pharmazeutische Salze |
| US6503532B1 (en) * | 2001-04-13 | 2003-01-07 | Murty Pharmaceuticals, Inc. | Pharmaceutical composition containing tetrahydrocannabinol and a transdermal/transcutaneous delivery method thereof |
| US6946150B2 (en) * | 2002-08-14 | 2005-09-20 | Gw Pharma Limited | Pharmaceutical formulation |
| GB2391865B (en) * | 2002-08-14 | 2005-06-01 | Gw Pharma Ltd | Improvements in the extraction of pharmaceutically active components from plant materials |
| US8911751B2 (en) * | 2005-10-11 | 2014-12-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions for nasal delivery |
| BRPI0715328A2 (pt) * | 2006-08-04 | 2013-07-09 | Insys Therapeutics Inc | formulaÇço, e, dispositivo de dose unitÁria ou de dose méltipla para a administraÇço sublingual de uma droga |
| US20090181080A1 (en) * | 2007-08-06 | 2009-07-16 | Insys Therapeutics Inc. | Oral cannabinnoid liquid formulations and methods of treatment |
| LT2280687T (lt) * | 2008-03-26 | 2019-08-26 | Stichting Sanammad | Kramtomosios gumos kompozicijos, apimančios kanabinoidus |
| EP2317989A4 (en) * | 2008-08-29 | 2013-08-28 | Sun Pharma Advanced Res Co Ltd | MICROPARTICLES |
| JP5614571B2 (ja) | 2009-12-25 | 2014-10-29 | ダイヤ製薬株式会社 | 咀嚼用ガム医薬品および咀嚼用ガム医薬品の製造方法 |
| EP2680828A4 (en) | 2011-02-28 | 2014-07-30 | Technologies Khlôros Inc | COUGAR MEANS FOR ORAL ABSORPTION |
| WO2013009928A1 (en) * | 2011-07-11 | 2013-01-17 | Organic Medical Research | Cannabinoid formulations |
| US9345771B2 (en) * | 2012-10-04 | 2016-05-24 | Insys Development Company, Inc. | Oral cannabinoid formulations |
| WO2015117011A1 (en) * | 2014-01-31 | 2015-08-06 | Pocket Tea, Llc | Tea composition for oral administration |
| US20160199299A1 (en) | 2015-01-09 | 2016-07-14 | Mark B. Uren | Cannabis Infused Chewing Composition |
| CN105124747B (zh) | 2015-07-21 | 2018-04-10 | 中国烟草总公司广东省公司 | 一种烟草提取物微粒和胶基型口香烟及其制备方法 |
| WO2017202424A1 (en) | 2016-05-27 | 2017-11-30 | Medcan Pharma A/S | Powdered composition comprising a complex between a cannabinoid and a basic ion exchange resin |
| CA2937471C (en) * | 2016-07-28 | 2019-02-05 | Allen Greenspoon | Orally administrable formulation |
| US9833408B1 (en) * | 2016-07-28 | 2017-12-05 | Allen Greenspoon | Orally administrable formulation |
-
2016
- 2016-07-28 US US15/222,019 patent/US9833408B1/en active Active
-
2017
- 2017-07-28 AU AU2017301239A patent/AU2017301239B2/en not_active Ceased
- 2017-07-28 EP EP17833153.4A patent/EP3490539B1/en active Active
- 2017-07-28 CU CU2019000005A patent/CU20190005A7/es unknown
- 2017-07-28 PE PE2019000281A patent/PE20190738A1/es unknown
- 2017-07-28 BR BR122020007418-3A patent/BR122020007418B1/pt active IP Right Grant
- 2017-07-28 MX MX2019001169A patent/MX383529B/es unknown
- 2017-07-28 JP JP2019526350A patent/JP7050777B2/ja not_active Expired - Fee Related
- 2017-07-28 BR BR112019001572-8A patent/BR112019001572B1/pt not_active IP Right Cessation
- 2017-07-28 WO PCT/CA2017/050904 patent/WO2018018152A1/en not_active Ceased
- 2017-07-28 EP EP24160275.4A patent/EP4353221A3/en not_active Withdrawn
- 2017-11-08 US US15/806,928 patent/US10456357B2/en active Active
-
2019
- 2019-01-25 CL CL2019000209A patent/CL2019000209A1/es unknown
- 2019-01-27 IL IL264484A patent/IL264484A/en unknown
- 2019-02-21 ZA ZA2019/01116A patent/ZA201901116B/en unknown
- 2019-02-27 CO CONC2019/0001895A patent/CO2019001895A2/es unknown
-
2020
- 2020-02-19 ZA ZA2020/01037A patent/ZA202001037B/en unknown
- 2020-10-21 AU AU2020257071A patent/AU2020257071B2/en not_active Ceased
-
2022
- 2022-03-29 JP JP2022054535A patent/JP2022088537A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX383529B (es) | 2025-03-14 |
| AU2017301239A1 (en) | 2019-03-14 |
| EP4353221A2 (en) | 2024-04-17 |
| JP2019525963A (ja) | 2019-09-12 |
| EP4353221A3 (en) | 2024-07-10 |
| AU2017301239B2 (en) | 2020-10-08 |
| EP3490539B1 (en) | 2024-03-13 |
| JP7050777B2 (ja) | 2022-04-08 |
| MX2019001169A (es) | 2019-08-29 |
| ZA202001037B (en) | 2020-07-29 |
| CU20190005A7 (es) | 2020-03-04 |
| CO2019001895A2 (es) | 2019-05-31 |
| EP3490539A1 (en) | 2019-06-05 |
| US20180064645A1 (en) | 2018-03-08 |
| IL264484A (en) | 2019-02-28 |
| JP2022088537A (ja) | 2022-06-14 |
| ZA201901116B (en) | 2020-10-28 |
| AU2020257071B2 (en) | 2021-03-25 |
| EP3490539A4 (en) | 2020-08-12 |
| BR112019001572B1 (pt) | 2021-11-03 |
| US9833408B1 (en) | 2017-12-05 |
| BR122020007418B1 (pt) | 2021-11-03 |
| US10456357B2 (en) | 2019-10-29 |
| BR112019001572A2 (pt) | 2019-05-07 |
| PE20190738A1 (es) | 2019-05-23 |
| AU2020257071A1 (en) | 2020-11-19 |
| WO2018018152A1 (en) | 2018-02-01 |
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