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CL2017001632A1 - Manufactura de proteína. - Google Patents

Manufactura de proteína.

Info

Publication number
CL2017001632A1
CL2017001632A1 CL2017001632A CL2017001632A CL2017001632A1 CL 2017001632 A1 CL2017001632 A1 CL 2017001632A1 CL 2017001632 A CL2017001632 A CL 2017001632A CL 2017001632 A CL2017001632 A CL 2017001632A CL 2017001632 A1 CL2017001632 A1 CL 2017001632A1
Authority
CL
Chile
Prior art keywords
protein
protein manufacturing
manufacture
refers
manufacturing
Prior art date
Application number
CL2017001632A
Other languages
English (en)
Inventor
Philip Bassett
Richard Davies
Elena Gonzalez
Higgins Mark Pearce
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52292664&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017001632(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of CL2017001632A1 publication Critical patent/CL2017001632A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

<p>LA PRESENTE INVENCIÓN SE REFIERE A UN MÉTODO NOVEDOSO DE MANUFACTURA DE PROTEÍNA EN DONDE LA PROTEÍNA ES EXPRESADA EN UNA CÉLULA HUÉSPED, Y EN UNA MANERA MÁS ESPECIFICA, SE REFIERE A UN MÉTODO PARA MANUFACTURAR UNA PROTEÍNA QUE RESULTA EN NIVELES REDUCIDOS DE IMPUREZAS RELACIONADAS CON EL PRODUCTO.</p>
CL2017001632A 2014-12-22 2017-06-20 Manufactura de proteína. CL2017001632A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14199717 2014-12-22

Publications (1)

Publication Number Publication Date
CL2017001632A1 true CL2017001632A1 (es) 2017-11-24

Family

ID=52292664

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017001632A CL2017001632A1 (es) 2014-12-22 2017-06-20 Manufactura de proteína.

Country Status (24)

Country Link
US (1) US10358460B2 (es)
EP (2) EP3237432B1 (es)
JP (1) JP6807327B2 (es)
KR (1) KR102533455B1 (es)
CN (1) CN107108692B (es)
AU (1) AU2015371346B2 (es)
BR (1) BR112017013394B1 (es)
CA (1) CA2969889A1 (es)
CL (1) CL2017001632A1 (es)
CO (1) CO2017006156A2 (es)
DK (1) DK3237432T3 (es)
EA (1) EA201791424A1 (es)
ES (1) ES2965032T3 (es)
FI (1) FI3237432T3 (es)
HR (1) HRP20231408T1 (es)
IL (1) IL252696B (es)
LT (1) LT3237432T (es)
MX (1) MX390701B (es)
MY (1) MY180732A (es)
PL (1) PL3237432T3 (es)
PT (1) PT3237432T (es)
SG (1) SG11201704836XA (es)
SI (1) SI3237432T1 (es)
WO (1) WO2016102383A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201001791D0 (en) * 2010-02-03 2010-03-24 Ucb Pharma Sa Process for obtaining antibodies
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
JP6807326B2 (ja) 2014-12-22 2021-01-06 ユーシービー バイオファルマ エスアールエル タンパク質製造方法
EP3824906A1 (en) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antibody formulations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8720833D0 (en) 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
GB9215540D0 (en) * 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
FR2716640B1 (fr) 1994-02-28 1996-05-03 Procedes Machines Speciales Dispositif de centrage et de blocage d'une pièce en vue de son rodage à l'aide d'un rodoir à expansion.
US5655866A (en) 1995-03-20 1997-08-12 Bellanca; Joseph V. Method of folding a signature for use in bookbinding
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
TWI327597B (en) 2001-08-01 2010-07-21 Centocor Inc Anti-tnf antibodies, compositions, methods and uses
US7052916B2 (en) * 2002-05-24 2006-05-30 Immunex Corporation Polypeptide analyses using stable isotope labeling
GB0319601D0 (en) 2003-08-20 2003-09-24 Sandoz Ag Production process
GB0425534D0 (en) 2004-11-19 2004-12-22 Celltech R&D Ltd Process for obtaining antibodies
US8470552B2 (en) 2009-10-12 2013-06-25 Keck Graduate Institute Strategy to reduce lactic acid production and control PH in animal cell culture
GB201000590D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial host strain
GB201000587D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201000591D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201001791D0 (en) * 2010-02-03 2010-03-24 Ucb Pharma Sa Process for obtaining antibodies
GB201012599D0 (en) * 2010-07-27 2010-09-08 Ucb Pharma Sa Process for purifying proteins
RS56926B1 (sr) 2011-07-13 2018-05-31 Ucb Biopharma Sprl Bakterijski soj domaćina koji izražava rekombinantnu dsbc
JP6807326B2 (ja) 2014-12-22 2021-01-06 ユーシービー バイオファルマ エスアールエル タンパク質製造方法

Also Published As

Publication number Publication date
JP2018505693A (ja) 2018-03-01
IL252696B (en) 2021-04-29
BR112017013394B1 (pt) 2024-02-06
EP3237432A1 (en) 2017-11-01
EP3237432B1 (en) 2023-09-06
AU2015371346B2 (en) 2021-05-13
KR20170093984A (ko) 2017-08-16
US20170362272A1 (en) 2017-12-21
FI3237432T3 (fi) 2023-11-03
AU2015371346A1 (en) 2017-06-29
HRP20231408T1 (hr) 2024-02-16
EP4253548A3 (en) 2024-01-03
LT3237432T (lt) 2023-12-11
DK3237432T3 (da) 2023-11-20
EP4253548A2 (en) 2023-10-04
PT3237432T (pt) 2023-11-28
CN107108692A (zh) 2017-08-29
MY180732A (en) 2020-12-08
PL3237432T3 (pl) 2024-03-04
MX390701B (es) 2025-03-21
IL252696A0 (en) 2017-08-31
CO2017006156A2 (es) 2017-09-11
SG11201704836XA (en) 2017-07-28
CN107108692B (zh) 2021-01-29
SI3237432T1 (sl) 2023-12-29
MX2017007684A (es) 2017-10-27
KR102533455B1 (ko) 2023-05-16
BR112017013394A2 (pt) 2018-03-06
WO2016102383A1 (en) 2016-06-30
US10358460B2 (en) 2019-07-23
JP6807327B2 (ja) 2021-01-06
ES2965032T3 (es) 2024-04-10
EA201791424A1 (ru) 2017-10-31
CA2969889A1 (en) 2016-06-30

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