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CL2016001340A1 - Anticuerpos neutralizantes de citomegalovirus humano y uso de los mismos (divisional de sol. n° 1293-14, la cual es a su vez, divisional de sol. n° 84-11). - Google Patents

Anticuerpos neutralizantes de citomegalovirus humano y uso de los mismos (divisional de sol. n° 1293-14, la cual es a su vez, divisional de sol. n° 84-11).

Info

Publication number
CL2016001340A1
CL2016001340A1 CL2016001340A CL2016001340A CL2016001340A1 CL 2016001340 A1 CL2016001340 A1 CL 2016001340A1 CL 2016001340 A CL2016001340 A CL 2016001340A CL 2016001340 A CL2016001340 A CL 2016001340A CL 2016001340 A1 CL2016001340 A1 CL 2016001340A1
Authority
CL
Chile
Prior art keywords
divisional
sol
neutralizing antibodies
divisional sol
human cytomegalovirus
Prior art date
Application number
CL2016001340A
Other languages
English (en)
Inventor
Antonio Lanzavecchia
Annalisa Macagno
Original Assignee
Inst Res Biomedicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41550776&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2016001340(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Inst Res Biomedicine filed Critical Inst Res Biomedicine
Publication of CL2016001340A1 publication Critical patent/CL2016001340A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/088—Varicella-zoster virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01D—HARVESTING; MOWING
    • A01D34/00—Mowers; Mowing apparatus of harvesters
    • A01D34/01—Mowers; Mowing apparatus of harvesters characterised by features relating to the type of cutting apparatus
    • A01D34/412—Mowers; Mowing apparatus of harvesters characterised by features relating to the type of cutting apparatus having rotating cutters
    • A01D34/63—Mowers; Mowing apparatus of harvesters characterised by features relating to the type of cutting apparatus having rotating cutters having cutters rotating about a vertical axis
    • A01D34/71—Mowers; Mowing apparatus of harvesters characterised by features relating to the type of cutting apparatus having rotating cutters having cutters rotating about a vertical axis with means for discharging mown material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12—Antivirals
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
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    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/089—Cytomegalovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01D—HARVESTING; MOWING
    • A01D34/00—Mowers; Mowing apparatus of harvesters
    • A01D34/01—Mowers; Mowing apparatus of harvesters characterised by features relating to the type of cutting apparatus
    • A01D34/412—Mowers; Mowing apparatus of harvesters characterised by features relating to the type of cutting apparatus having rotating cutters
    • A01D34/63—Mowers; Mowing apparatus of harvesters characterised by features relating to the type of cutting apparatus having rotating cutters having cutters rotating about a vertical axis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Abstract

ANTICUERPOS NEUTRALIZANTES DE CITOMEGALOVIRUS HUMANO (hCMV); ACIDO NUCLEICO QUE LO CODIFICA; VECTOR; CÉLULA HUÉSPED; COMPOSICIÓN QUE LOS COMPRENDE; Y USO PARA INHIBIR INFECCIÓN POR hCMV(DIVISIONAL DE SOL. N° 1293-14, LA CUAL ES A SU VEZ, DIVISIONAL DE SOL. N° 84-11).
CL2016001340A 2008-07-16 2016-06-01 Anticuerpos neutralizantes de citomegalovirus humano y uso de los mismos (divisional de sol. n° 1293-14, la cual es a su vez, divisional de sol. n° 84-11). CL2016001340A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8133408P 2008-07-16 2008-07-16
CL2011000084A CL2011000084A1 (es) 2008-07-16 2011-01-14 Anticuerpo monoclonal o fragmento enlazante a antigeno del mismo que se une al citomegalovirus humano (hcmv); molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; y composicion que lo comprende.
CL2014001293A CL2014001293A1 (es) 2008-07-16 2014-05-16 Anticuerpo monocional o fragmento enlazante a antigeno del mismo, especifico para proteinas de citomegalovirus humano (hcmv); molecula de acido nucleico que lo codifica; celula huesped; metodo de produccion; composicion que lo comprende; y su uso para el tratamiento de infeccion por hcmv (div sol 84-2011)

Publications (1)

Publication Number Publication Date
CL2016001340A1 true CL2016001340A1 (es) 2016-10-28

Family

ID=41550776

Family Applications (3)

Application Number Title Priority Date Filing Date
CL2011000084A CL2011000084A1 (es) 2008-07-16 2011-01-14 Anticuerpo monoclonal o fragmento enlazante a antigeno del mismo que se une al citomegalovirus humano (hcmv); molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; y composicion que lo comprende.
CL2014001293A CL2014001293A1 (es) 2008-07-16 2014-05-16 Anticuerpo monocional o fragmento enlazante a antigeno del mismo, especifico para proteinas de citomegalovirus humano (hcmv); molecula de acido nucleico que lo codifica; celula huesped; metodo de produccion; composicion que lo comprende; y su uso para el tratamiento de infeccion por hcmv (div sol 84-2011)
CL2016001340A CL2016001340A1 (es) 2008-07-16 2016-06-01 Anticuerpos neutralizantes de citomegalovirus humano y uso de los mismos (divisional de sol. n° 1293-14, la cual es a su vez, divisional de sol. n° 84-11).

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CL2011000084A CL2011000084A1 (es) 2008-07-16 2011-01-14 Anticuerpo monoclonal o fragmento enlazante a antigeno del mismo que se une al citomegalovirus humano (hcmv); molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; y composicion que lo comprende.
CL2014001293A CL2014001293A1 (es) 2008-07-16 2014-05-16 Anticuerpo monocional o fragmento enlazante a antigeno del mismo, especifico para proteinas de citomegalovirus humano (hcmv); molecula de acido nucleico que lo codifica; celula huesped; metodo de produccion; composicion que lo comprende; y su uso para el tratamiento de infeccion por hcmv (div sol 84-2011)

Country Status (30)

Country Link
US (21) US8603480B2 (es)
EP (3) EP2352759B1 (es)
JP (5) JP5422649B2 (es)
KR (1) KR101356350B1 (es)
CN (3) CN103980363B (es)
AU (1) AU2009272284C1 (es)
BR (1) BRPI0916443A2 (es)
CA (2) CA2730776C (es)
CL (3) CL2011000084A1 (es)
CO (1) CO6351801A2 (es)
CR (2) CR20160355A (es)
CU (1) CU23953B1 (es)
DK (2) DK3009449T3 (es)
EA (1) EA031177B1 (es)
EC (2) ECSP11010826A (es)
ES (2) ES2682596T3 (es)
GT (4) GT201100011CA (es)
HN (1) HN2011000161A (es)
IL (7) IL210356A (es)
MA (1) MA32561B1 (es)
MX (5) MX338067B (es)
NZ (5) NZ591056A (es)
PE (7) PE20140882A1 (es)
PH (1) PH12015500782A1 (es)
PL (2) PL2352759T3 (es)
PT (2) PT3009449T (es)
SG (3) SG191699A1 (es)
UA (1) UA106354C2 (es)
WO (1) WO2010007533A2 (es)
ZA (1) ZA201600335B (es)

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JP5807050B2 (ja) 2015-11-10
PH12015500782A1 (en) 2015-12-14
US20120128691A1 (en) 2012-05-24
US20150353627A1 (en) 2015-12-10
PL3009449T3 (pl) 2018-09-28
CA2730776C (en) 2018-12-11
US9796772B2 (en) 2017-10-24
DK2352759T3 (en) 2017-12-18
IL232864A0 (en) 2014-07-31
US9803000B1 (en) 2017-10-31
NZ603498A (en) 2014-02-28
JP6062477B2 (ja) 2017-01-18
US9365636B1 (en) 2016-06-14
US10414817B2 (en) 2019-09-17
US20130302350A1 (en) 2013-11-14
SG10201706350PA (en) 2017-09-28
UA106354C2 (ru) 2014-08-26
US9725502B2 (en) 2017-08-08
CN106924729B (zh) 2021-03-02
PE20141435A1 (es) 2014-10-22
CL2014001293A1 (es) 2014-12-05

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