CL2016001165A1 - Proceso preparativo. (divisional sol. n° 3003-2014) - Google Patents
Proceso preparativo. (divisional sol. n° 3003-2014)Info
- Publication number
- CL2016001165A1 CL2016001165A1 CL2016001165A CL2016001165A CL2016001165A1 CL 2016001165 A1 CL2016001165 A1 CL 2016001165A1 CL 2016001165 A CL2016001165 A CL 2016001165A CL 2016001165 A CL2016001165 A CL 2016001165A CL 2016001165 A1 CL2016001165 A1 CL 2016001165A1
- Authority
- CL
- Chile
- Prior art keywords
- triazol
- preparatory process
- divisional
- sol
- divisional sol
- Prior art date
Links
- XEKOWRVHYACXOJ-UHFFFAOYSA-N ethyl acetate Substances CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 2
- QWENRTYMTSOGBR-UHFFFAOYSA-N 1H-1,2,3-Triazole Chemical compound C=1C=NNN=1 QWENRTYMTSOGBR-UHFFFAOYSA-N 0.000 abstract 1
- JGFZNNIVVJXRND-UHFFFAOYSA-N N,N-Diisopropylethylamine (DIPEA) Chemical compound CCN(C(C)C)C(C)C JGFZNNIVVJXRND-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- YDCHPLOFQATIDS-UHFFFAOYSA-N methyl 2-bromoacetate Chemical compound COC(=O)CBr YDCHPLOFQATIDS-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCESO DE PREPARACION DE 1H-1,2,3-TRIAZOL-1-IL-ACETATO DE METILO (V-ME) Y 2H-1,2,3-TRIAZOL-1-IL-ACETATO DE METILO (VI-ME) O COMPUESTOS 1H-1,2,3-TRIAZOL-1-IL-ACETATO DE ETILO (V-ET) Y 2H-1,2,3-TRIAZOL-1-IL-ACETATO DE ETILO (VI-ET), QUE COMPRENDE HACER REACCIONAR 1,2,3-TRIAZOL CON BROMOACETATO DE METILO O ETILO EN PRESENCIA DE ETILDIISOPROPILAMINA EN UN DISOLVENTE, A TEMPERATURA ENTRE 20 Y 80°C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12167152 | 2012-05-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2016001165A1 true CL2016001165A1 (es) | 2016-12-02 |
Family
ID=48325714
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014003003A CL2014003003A1 (es) | 2012-05-08 | 2014-11-06 | Proceso para la preparacion de 1-[6-(morfolin—4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1h-pirazol-5-ol (i – forma enol) o de 2-[6-(morfolin-4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1,2-dihidro-3h-pirazol-3-ona (i – forma ceto); y compuesto intermediario (2e/z)-3-(dimetilamino)-2-(1h-1,2,3-triazol-1-il) acrilato de metilo. |
| CL2016001165A CL2016001165A1 (es) | 2012-05-08 | 2016-05-13 | Proceso preparativo. (divisional sol. n° 3003-2014) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014003003A CL2014003003A1 (es) | 2012-05-08 | 2014-11-06 | Proceso para la preparacion de 1-[6-(morfolin—4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1h-pirazol-5-ol (i – forma enol) o de 2-[6-(morfolin-4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1,2-dihidro-3h-pirazol-3-ona (i – forma ceto); y compuesto intermediario (2e/z)-3-(dimetilamino)-2-(1h-1,2,3-triazol-1-il) acrilato de metilo. |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US10301289B2 (es) |
| EP (1) | EP2847183B1 (es) |
| JP (1) | JP6149104B2 (es) |
| KR (1) | KR102086389B1 (es) |
| CN (1) | CN104411704B (es) |
| AP (1) | AP2014008089A0 (es) |
| AU (1) | AU2013258107B2 (es) |
| BR (1) | BR112014027564B1 (es) |
| CA (1) | CA2872726C (es) |
| CL (2) | CL2014003003A1 (es) |
| CO (1) | CO7121324A2 (es) |
| CR (1) | CR20140514A (es) |
| CU (1) | CU20140128A7 (es) |
| DK (1) | DK2847183T3 (es) |
| DO (1) | DOP2014000254A (es) |
| EA (1) | EA027804B1 (es) |
| ES (1) | ES2641205T3 (es) |
| HR (1) | HRP20171321T1 (es) |
| HU (1) | HUE034430T2 (es) |
| IL (1) | IL235441A (es) |
| LT (1) | LT2847183T (es) |
| MX (1) | MX350519B (es) |
| MY (1) | MY184577A (es) |
| NZ (1) | NZ701661A (es) |
| PE (1) | PE20142453A1 (es) |
| PH (1) | PH12014502482A1 (es) |
| PL (1) | PL2847183T3 (es) |
| PT (1) | PT2847183T (es) |
| RS (1) | RS56255B1 (es) |
| SG (2) | SG11201407043PA (es) |
| SI (1) | SI2847183T1 (es) |
| TN (1) | TN2014000469A1 (es) |
| UA (1) | UA116349C2 (es) |
| WO (1) | WO2013167552A1 (es) |
| ZA (1) | ZA201408571B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2639716B2 (ja) | 1988-12-14 | 1997-08-13 | 横浜ゴム株式会社 | タイヤ成形装置に於けるグリーンタイヤの搬送装置 |
| US10703742B2 (en) * | 2016-05-03 | 2020-07-07 | Bayer Pharma Aktiengesellschaft | Method for producing 5-hydroxyalkyl-substituted 1-phenyl-1,2,4-triazole derivatives |
| CN108084099B (zh) * | 2017-12-20 | 2019-01-29 | 天驰药业有限公司 | 一种1,2,3-三氮唑化合物的合成方法 |
| US10702525B1 (en) | 2019-09-04 | 2020-07-07 | United Arab Emirates University | Pyrimidine derivatives as anti-diabetic agents |
| EP3888684A1 (en) | 2020-03-31 | 2021-10-06 | Bayer Animal Health GmbH | Composition having improved voluntary acceptance |
| JP7710897B2 (ja) * | 2021-06-01 | 2025-07-22 | 三菱ガス化学ネクスト株式会社 | １－アルキル－５－ヒドロキシピラゾールの製造方法 |
| CN114264752B (zh) * | 2021-12-29 | 2023-08-15 | 北京金城泰尔制药有限公司 | 溴乙酸甲酯的检测方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4572910A (en) * | 1983-03-03 | 1986-02-25 | Riker Laboratories, Inc. | Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing heterocyclic rings |
| DK135184A (da) | 1983-03-03 | 1984-10-10 | Riker Laboratories Inc | Triazol(4,3-c)- og triazol(1,5-c)pyrimidiner |
| US4752910A (en) | 1984-10-30 | 1988-06-21 | Prime Computer, Inc. | Method and apparatus for continuous after-imaging |
| UY27813A1 (es) * | 2002-05-31 | 2003-12-31 | Smithkline Beecham Corp | Inhibidores de la peptido-desformilasa |
| CL2003002353A1 (es) | 2002-11-15 | 2005-02-04 | Vertex Pharma | Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic |
| CA2543882A1 (en) * | 2003-10-30 | 2005-05-19 | Merck & Co., Inc. | Aralkyl amines as cannabinoid receptor modulators |
| US7745630B2 (en) | 2003-12-22 | 2010-06-29 | Justin Stephen Bryans | Triazolyl piperidine arginine vasopressin receptor modulators |
| DE102008020113A1 (de) | 2008-04-23 | 2009-10-29 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dihydropyrazolone und ihre Verwendung |
| CA2605899C (en) | 2005-04-26 | 2011-02-08 | Pfizer Limited | Triazole derivatives as vasopressin antagonists |
| US20080234252A1 (en) | 2005-05-18 | 2008-09-25 | Pfizer Inc | Compounds Useful in Therapy |
| DE102006050516A1 (de) * | 2006-10-26 | 2008-04-30 | Bayer Healthcare Ag | Substituierte Dihydropyrazolone und ihre Verwendung |
| DE102010041236A1 (de) * | 2010-09-23 | 2012-03-29 | Osram Ag | Optoelektronisches Halbleiterbauelement |
| DE102010044131A1 (de) * | 2010-11-18 | 2012-05-24 | Bayer Schering Pharma Aktiengesellschaft | Substituiertes Natrium-1H-pyrazol-5-olat |
-
2013
- 2013-05-06 KR KR1020147033989A patent/KR102086389B1/ko active Active
- 2013-05-06 EP EP13720943.3A patent/EP2847183B1/de active Active
- 2013-05-06 AU AU2013258107A patent/AU2013258107B2/en active Active
- 2013-05-06 ES ES13720943.3T patent/ES2641205T3/es active Active
- 2013-05-06 JP JP2015510775A patent/JP6149104B2/ja active Active
- 2013-05-06 MY MYPI2014703274A patent/MY184577A/en unknown
- 2013-05-06 DK DK13720943.3T patent/DK2847183T3/en active
- 2013-05-06 RS RS20170869A patent/RS56255B1/sr unknown
- 2013-05-06 PT PT137209433T patent/PT2847183T/pt unknown
- 2013-05-06 SG SG11201407043PA patent/SG11201407043PA/en unknown
- 2013-05-06 AP AP2014008089A patent/AP2014008089A0/xx unknown
- 2013-05-06 NZ NZ701661A patent/NZ701661A/en unknown
- 2013-05-06 UA UAA201413001A patent/UA116349C2/uk unknown
- 2013-05-06 MX MX2014013448A patent/MX350519B/es active IP Right Grant
- 2013-05-06 PL PL13720943T patent/PL2847183T3/pl unknown
- 2013-05-06 CN CN201380036548.5A patent/CN104411704B/zh active Active
- 2013-05-06 SI SI201330768T patent/SI2847183T1/sl unknown
- 2013-05-06 BR BR112014027564-5A patent/BR112014027564B1/pt active IP Right Grant
- 2013-05-06 EA EA201492032A patent/EA027804B1/ru not_active IP Right Cessation
- 2013-05-06 PE PE2014001942A patent/PE20142453A1/es active IP Right Grant
- 2013-05-06 HR HRP20171321TT patent/HRP20171321T1/hr unknown
- 2013-05-06 SG SG10201609319YA patent/SG10201609319YA/en unknown
- 2013-05-06 HU HUE13720943A patent/HUE034430T2/en unknown
- 2013-05-06 LT LTEP13720943.3T patent/LT2847183T/lt unknown
- 2013-05-06 US US14/399,929 patent/US10301289B2/en active Active
- 2013-05-06 WO PCT/EP2013/059418 patent/WO2013167552A1/de not_active Ceased
- 2013-05-06 CA CA2872726A patent/CA2872726C/en active Active
-
2014
- 2014-11-02 IL IL235441A patent/IL235441A/en active IP Right Grant
- 2014-11-04 CO CO14243310A patent/CO7121324A2/es unknown
- 2014-11-06 CL CL2014003003A patent/CL2014003003A1/es unknown
- 2014-11-06 CU CU2014000128A patent/CU20140128A7/es unknown
- 2014-11-06 PH PH12014502482A patent/PH12014502482A1/en unknown
- 2014-11-07 TN TN2014000469A patent/TN2014000469A1/fr unknown
- 2014-11-07 CR CR20140514A patent/CR20140514A/es unknown
- 2014-11-07 DO DO2014000254A patent/DOP2014000254A/es unknown
- 2014-11-21 ZA ZA2014/08571A patent/ZA201408571B/en unknown
-
2016
- 2016-05-13 CL CL2016001165A patent/CL2016001165A1/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CL2016001165A1 (es) | Proceso preparativo. (divisional sol. n° 3003-2014) | |
| MX2014010551A (es) | N-ciclilamidas como nematicidas. | |
| EP2824107A4 (en) | ANSA-METALLOCEN COMPOUND AND METHOD FOR PRODUCING A SUPPORTED CATALYST THEREWITH | |
| WO2014025719A3 (en) | Test specimen holder for high temperature environments | |
| NZ734919A (en) | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | |
| EP4545544A3 (en) | Modified crispr rna and modified single crispr rna and uses thereof | |
| EA201071234A1 (ru) | Производные изохинолинона в качестве nk3 антагонистов | |
| UY33397A (es) | Forma sólida de un naftaleno carboxamida | |
| EP2566859A4 (en) | PICOLINAMIDE AND PYRIMIDINE-4-CARBOXAMIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION THEREWITH | |
| MX2015007189A (es) | Composiciones que comprenden anticuerpos anti-cd38 y lenalidomida. | |
| CR20170111A (es) | Derivados de benzodiazepina citotóxicos | |
| EP2639234A4 (en) | CRYSTALLINE 6,7-NON-SATURATED 7-CARBAMOYL-MORPHINAN DERIVATIVE AND METHOD OF PREPARING THEREOF | |
| EP2867230A4 (en) | PROCESS FOR PREPARING 3,5-DISUBSTITUTED 1,2,4-OXADIAZOLES | |
| NZ726521A (en) | Pesticidal compositions and processes related thereto | |
| DK2773633T3 (da) | Heterocykliske forbindelser, medikamenter indeholdende forbindelserne, anvendelse deraf og fremgangsmåder til fremstilling deraf. | |
| EP3012256A4 (en) | HETEROCYCLIC BENZIMIDAZOLE-2-PIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, METHOD OF MANUFACTURE AND USE THEREOF | |
| NZ731103A (en) | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | |
| NZ728484A (en) | Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto | |
| CA2879720A1 (en) | Apparatus, systems, and methods for performing thermal melt analyses and amplifications | |
| MX373308B (es) | Composiciones que comprenden anticuerpos anti-cd38 y carfilzomib. | |
| EP2573072A4 (en) | INDENOCHINOLINE COMPOUND, METHOD OF MANUFACTURE AND APPLICATION THEREOF | |
| MX2018002700A (es) | Moleculas que tienen utilidad plaguicida, e intermediarios, composiciones y procesos, relacionados con ellas. | |
| NZ726907A (en) | Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto | |
| PH12015501054A1 (en) | Pyridiyloxyalkyl carboxamides and use thereof as endoparasiticides and nematicides | |
| WO2014197197A8 (en) | High temperature geomembrane liners and master batch compositions |