CL2014001823A1 - Procedimiento de preparacion estereoselectiva de un compuesto derivado de 9-hidroxi-5-oxo-1,4-diaza-espiro [5.5] undecano; compuestos intermediarios; uso en el tratamiento de enfermedades tumorales, enfermedades del pulmon y de las vias respiratorias. - Google Patents
Procedimiento de preparacion estereoselectiva de un compuesto derivado de 9-hidroxi-5-oxo-1,4-diaza-espiro [5.5] undecano; compuestos intermediarios; uso en el tratamiento de enfermedades tumorales, enfermedades del pulmon y de las vias respiratorias.Info
- Publication number
- CL2014001823A1 CL2014001823A1 CL2014001823A CL2014001823A CL2014001823A1 CL 2014001823 A1 CL2014001823 A1 CL 2014001823A1 CL 2014001823 A CL2014001823 A CL 2014001823A CL 2014001823 A CL2014001823 A CL 2014001823A CL 2014001823 A1 CL2014001823 A1 CL 2014001823A1
- Authority
- CL
- Chile
- Prior art keywords
- diseases
- undecano
- diaza
- spiro
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12154688 | 2012-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014001823A1 true CL2014001823A1 (es) | 2015-03-06 |
Family
ID=47678813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014001823A CL2014001823A1 (es) | 2012-02-09 | 2014-07-09 | Procedimiento de preparacion estereoselectiva de un compuesto derivado de 9-hidroxi-5-oxo-1,4-diaza-espiro [5.5] undecano; compuestos intermediarios; uso en el tratamiento de enfermedades tumorales, enfermedades del pulmon y de las vias respiratorias. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8629146B2 (es) |
| EP (1) | EP2812317B1 (es) |
| JP (1) | JP6105631B2 (es) |
| KR (1) | KR20140128318A (es) |
| CN (1) | CN104080775A (es) |
| AU (1) | AU2013218119A1 (es) |
| BR (1) | BR112014019196A8 (es) |
| CA (1) | CA2862520A1 (es) |
| CL (1) | CL2014001823A1 (es) |
| EA (1) | EA201400882A1 (es) |
| IL (1) | IL233370A (es) |
| MX (1) | MX2014009033A (es) |
| PH (1) | PH12014501760A1 (es) |
| WO (1) | WO2013117568A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2289881A1 (de) * | 2009-08-06 | 2011-03-02 | Boehringer Ingelheim International GmbH | Verfahren zur stereoselektiven Synthese bicyclischer Heterocyclen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4575507A (en) * | 1985-05-29 | 1986-03-11 | Pfizer Inc. | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
| US6924285B2 (en) | 2002-03-30 | 2005-08-02 | Boehringer Ingelheim Pharma Gmbh & Co. | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them |
| MXPA04009536A (es) | 2002-03-30 | 2005-01-25 | Boehringer Ingelheim Pharma | Compuestos heterociclos biciclicos, composiciones farmaceuticas que contienen estos compuestos, su utilizacion y procesos para su preparacion. |
| AU2006326157A1 (en) | 2005-12-12 | 2007-06-21 | Boehringer Ingelheim International Gmbh | Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for the production thereof |
| BRPI0907916A2 (pt) | 2008-02-07 | 2015-07-28 | Boehringer Ingelheim Int | Heterociclos espirociclos, medicamentos contendo esses compostos, e processos para preparar os mesmos |
| EP2289881A1 (de) | 2009-08-06 | 2011-03-02 | Boehringer Ingelheim International GmbH | Verfahren zur stereoselektiven Synthese bicyclischer Heterocyclen |
| EA023573B1 (ru) | 2011-02-01 | 2016-06-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Дималеат 9-[4-(3-хлор-2-фторфениламино)-7-метоксихиназолин-6-илокси]-1,4-диазаспиро[5.5]ундекан-5-она, его применение в качестве лекарственного средства и его получение |
-
2013
- 2013-02-06 JP JP2014556029A patent/JP6105631B2/ja active Active
- 2013-02-06 EP EP13703045.8A patent/EP2812317B1/de active Active
- 2013-02-06 WO PCT/EP2013/052287 patent/WO2013117568A1/de not_active Ceased
- 2013-02-06 BR BR112014019196A patent/BR112014019196A8/pt not_active IP Right Cessation
- 2013-02-06 CN CN201380006918.0A patent/CN104080775A/zh active Pending
- 2013-02-06 AU AU2013218119A patent/AU2013218119A1/en not_active Abandoned
- 2013-02-06 MX MX2014009033A patent/MX2014009033A/es not_active Application Discontinuation
- 2013-02-06 EA EA201400882A patent/EA201400882A1/ru unknown
- 2013-02-06 KR KR1020147021922A patent/KR20140128318A/ko not_active Withdrawn
- 2013-02-06 CA CA2862520A patent/CA2862520A1/en not_active Abandoned
- 2013-02-07 US US13/761,211 patent/US8629146B2/en active Active
-
2014
- 2014-06-25 IL IL233370A patent/IL233370A/en not_active IP Right Cessation
- 2014-07-09 CL CL2014001823A patent/CL2014001823A1/es unknown
- 2014-08-05 PH PH12014501760A patent/PH12014501760A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA201400882A1 (ru) | 2015-01-30 |
| EP2812317A1 (de) | 2014-12-17 |
| JP6105631B2 (ja) | 2017-03-29 |
| KR20140128318A (ko) | 2014-11-05 |
| JP2015506966A (ja) | 2015-03-05 |
| IL233370A0 (en) | 2014-08-31 |
| CN104080775A (zh) | 2014-10-01 |
| PH12014501760B1 (en) | 2014-11-10 |
| AU2013218119A1 (en) | 2014-07-17 |
| US8629146B2 (en) | 2014-01-14 |
| PH12014501760A1 (en) | 2014-11-10 |
| BR112014019196A2 (es) | 2017-06-20 |
| BR112014019196A8 (pt) | 2017-07-11 |
| IL233370A (en) | 2015-04-30 |
| WO2013117568A1 (de) | 2013-08-15 |
| MX2014009033A (es) | 2014-10-17 |
| EP2812317B1 (de) | 2016-02-03 |
| US20130211081A1 (en) | 2013-08-15 |
| CA2862520A1 (en) | 2013-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL268094B (en) | History of heterocyclic compounds for use in the treatment of lung cancer | |
| CY1122292T1 (el) | Ενωσεις και μεθοδοι για αντιϊικη αγωγη | |
| HUE036000T2 (hu) | Claudin 18.2 ellen irányuló antitesteket magában foglaló kombinációs terápia rák kezelésére | |
| LT2726511T (lt) | Kompozicijos, panaudojimai ir būdai, skirti metabolinių sutrikimų ir ligų gydymui | |
| WO2011140517A9 (en) | Methods for treating diseases of the lung | |
| HUE053113T2 (hu) | Bardoxolon-metil 2,2-difluorpropionamid-származéka, annak gyógyszerkészítményei és polimorfjai bizonyos betegségek kezelésében történõ alkalmazásra | |
| IL230458A0 (en) | Compounds for the treatment and prevention of respiratory syncytial viral disease | |
| LT3292875T (lt) | Kompozicijos ir būdai, skirti ligų gydymui | |
| IL236356A0 (en) | Use of iron citrate to treat patients with chronic kidney disease | |
| IL225262A0 (en) | Methods and compositions for treating lung cancer | |
| PL2627345T3 (pl) | Preparaty do leczenia chorób górnych dróg oddechowych | |
| ZA201403549B (en) | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy of an acute disease or acute condition of a patient for stabilizing the circulation | |
| PL2771329T3 (pl) | Nowe związki di-podstawione 3,4-diamino-3-cyklobuteno- 1,2-dionu do zastosowania w leczeniu patologii, w których pośredniczą chemokiny | |
| PL2726470T3 (pl) | Pochodne 1,2,4-tiadiazol-5-ilo piperazyny przydatne w leczeniu chorób neurodegeneracyjnych | |
| PL3260865T3 (pl) | Sposób obróbki krwi, produktów krwiopochodnych i narządów | |
| IL260078B (en) | Therapy used to treat Gaucher disease | |
| LT2934479T (lt) | Ciklezonidas, skirtas arklių kvėpavimo takų ligų gydymui | |
| IL238722B (en) | New annals of indole for the treatment of cancer, viral infections, and lung disease | |
| BR112013006857A2 (pt) | composição farmacêutica, processo para preparar uma composição farmacêutica, uso de uma composição farmacêutica e método para o tratamento ou profilaxia de doenças virais | |
| WO2015150362A3 (de) | Chirale 2,5-disubstituierte cyclopentancarbonsäure-derivate und ihre verwendung | |
| PL2919780T3 (pl) | Pochodne 1,3-dihydroimidazolo-2-tionu do zastosowania w leczeniu tętniczego nadciśnienia płucnego i uszkodzenia płuc | |
| ZA201402477B (en) | Compounds for use in the treatment of alzheimer's disease | |
| CL2014001046A1 (es) | Proceso de preparacion de compuestos derivados de acilguanidinas y aciltioureas, utiles para el tratamiento de enfermedades de los pulmones y de las vias respiratorias; y compuestos intermediarios utilizados en dicho proceso. | |
| CL2014001823A1 (es) | Procedimiento de preparacion estereoselectiva de un compuesto derivado de 9-hidroxi-5-oxo-1,4-diaza-espiro [5.5] undecano; compuestos intermediarios; uso en el tratamiento de enfermedades tumorales, enfermedades del pulmon y de las vias respiratorias. | |
| PT3044215T (pt) | Processos para a preparação de medicamentos para o tratamento de doenças cardiovasculares e intermediários para utilização no mesmo |