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CL2013003813A1 - Procedure for obtaining carotenoids (in particular astaxanthin) from a powder microalgae substrate, which is compressed to form pellets, which are subjected to supercritical carbon dioxide (co2) extraction. - Google Patents

Procedure for obtaining carotenoids (in particular astaxanthin) from a powder microalgae substrate, which is compressed to form pellets, which are subjected to supercritical carbon dioxide (co2) extraction.

Info

Publication number
CL2013003813A1
CL2013003813A1 CL2013003813A CL2013003813A CL2013003813A1 CL 2013003813 A1 CL2013003813 A1 CL 2013003813A1 CL 2013003813 A CL2013003813 A CL 2013003813A CL 2013003813 A CL2013003813 A CL 2013003813A CL 2013003813 A1 CL2013003813 A1 CL 2013003813A1
Authority
CL
Chile
Prior art keywords
substrate
extraction
procedure
microalgae
compressed
Prior art date
Application number
CL2013003813A
Other languages
Spanish (es)
Inventor
Madrid Fabian Alberto Reyes
Montoya Gonzalo Nuñez
Valle Lladser Jose Manuel Del
Original Assignee
Univ Pontificia Catolica Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pontificia Catolica Chile filed Critical Univ Pontificia Catolica Chile
Priority to CL2013003813A priority Critical patent/CL2013003813A1/en
Publication of CL2013003813A1 publication Critical patent/CL2013003813A1/en
Priority to PCT/CL2014/000089 priority patent/WO2015123789A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/05—Chlorophycota or chlorophyta (green algae), e.g. Chlorella
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0203—Solvent extraction of solids with a supercritical fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Esta solicitud de invención esta relacionada a la obtención de bioactivos a partir de biomasa de microorganismos. Esta solicitud reivindica un procedimiento para la obtención de carotenoides (ejemplificado con astaxantina) a partir de un sustrato de microalgas que se provee como polvo (ejemplificado con el alga Haematococcus pluvialis), el que se comprime para formar pellets, los cuales son sometidos a extracción por dioxido de carbono (CO2) supercrítico. El procedimiento de extracción tiene un rendimiento promedio sobre el 10% (mg de astaxantina/ g de sustrato).This application for invention is related to obtaining bioactive from biomass of microorganisms. This application claims a procedure for obtaining carotenoids (exemplified with astaxanthin) from a microalgae substrate that is provided as a powder (exemplified with the Haematococcus pluvialis algae), which is compressed to form pellets, which are subjected to extraction by supercritical carbon dioxide (CO2). The extraction procedure has an average yield of 10% (mg of astaxanthin / g of substrate).

CL2013003813A 2013-12-31 2013-12-31 Procedure for obtaining carotenoids (in particular astaxanthin) from a powder microalgae substrate, which is compressed to form pellets, which are subjected to supercritical carbon dioxide (co2) extraction. CL2013003813A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CL2013003813A CL2013003813A1 (en) 2013-12-31 2013-12-31 Procedure for obtaining carotenoids (in particular astaxanthin) from a powder microalgae substrate, which is compressed to form pellets, which are subjected to supercritical carbon dioxide (co2) extraction.
PCT/CL2014/000089 WO2015123789A1 (en) 2013-12-31 2014-12-24 Method of producing carotenoid compounds from microalgal substrate including compression of the microalgal powder and extraction by supercritical co2

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2013003813A CL2013003813A1 (en) 2013-12-31 2013-12-31 Procedure for obtaining carotenoids (in particular astaxanthin) from a powder microalgae substrate, which is compressed to form pellets, which are subjected to supercritical carbon dioxide (co2) extraction.

Publications (1)

Publication Number Publication Date
CL2013003813A1 true CL2013003813A1 (en) 2014-06-06

Family

ID=53877490

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003813A CL2013003813A1 (en) 2013-12-31 2013-12-31 Procedure for obtaining carotenoids (in particular astaxanthin) from a powder microalgae substrate, which is compressed to form pellets, which are subjected to supercritical carbon dioxide (co2) extraction.

Country Status (2)

Country Link
CL (1) CL2013003813A1 (en)
WO (1) WO2015123789A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108929256B (en) * 2018-07-03 2019-08-20 华南理工大学 Broken wall lactobacillus supercritical CO2The static method for extracting astaxanthin with dynamic cooperation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7329789B1 (en) * 2001-10-25 2008-02-12 Phasex Corporation Method for extraction and concentration of carotenoids using supercritical fluids
WO2006047445A2 (en) * 2004-10-22 2006-05-04 Martek Biosciences Corporation Process for preparing materials for extraction
CA2825039C (en) * 2011-02-11 2020-04-28 E.I. Du Pont De Nemours And Company Method for obtaining a lipid-containing composition from microbial biomass
CN102911095A (en) * 2011-10-26 2013-02-06 江苏江大源生态生物科技有限公司 Method for supercritical CO2 extraction of effective ingredients of Haematococcus pluvialis spore powder

Also Published As

Publication number Publication date
WO2015123789A1 (en) 2015-08-27

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