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CL2013003797A1 - Proceso de separacion cromatografico para recuperar un producto de acido graso poliinsaturado (pufa) que comprende pasar la mezcla de alimentacion a traves de columnas cromatograficas con eluyente solvente organico acuoso y aplicar temperatura controlada; uso de dichas columnas calentadas; y producto pufa. - Google Patents

Proceso de separacion cromatografico para recuperar un producto de acido graso poliinsaturado (pufa) que comprende pasar la mezcla de alimentacion a traves de columnas cromatograficas con eluyente solvente organico acuoso y aplicar temperatura controlada; uso de dichas columnas calentadas; y producto pufa.

Info

Publication number
CL2013003797A1
CL2013003797A1 CL2013003797A CL2013003797A CL2013003797A1 CL 2013003797 A1 CL2013003797 A1 CL 2013003797A1 CL 2013003797 A CL2013003797 A CL 2013003797A CL 2013003797 A CL2013003797 A CL 2013003797A CL 2013003797 A1 CL2013003797 A1 CL 2013003797A1
Authority
CL
Chile
Prior art keywords
pufa
product
columns
chromatographic
recover
Prior art date
Application number
CL2013003797A
Other languages
English (en)
Inventor
Adam Kelliher
Angus Morrison
Anil Oroskar
Rema Rakesh Vikraman Nair
Abhilesh Agarwal
Original Assignee
Basf Pharma Callanish Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Pharma Callanish Ltd filed Critical Basf Pharma Callanish Ltd
Publication of CL2013003797A1 publication Critical patent/CL2013003797A1/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/185—Simulated moving beds characterised by the components to be separated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/161—Temperature conditioning
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/1828—Simulated moving beds characterised by process features
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1885—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in parallel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1892—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds or centrifugal chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3861—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography using an external stimulus
    • B01D15/3876—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography using an external stimulus modifying the temperature
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/006—Refining fats or fatty oils by extraction
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/10—Refining fats or fatty oils by adsorption
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08—Refining

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • General Chemical & Material Sciences (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

LA PRESENTE INVENCIÓN PROVEE UN PROCESO DE SEPARACIÓN CROMATOGRÁFICA PARA RECUPERAR UN PRODUCTO DE) ÁCIDO GRASO POLIINSATURADO (PUFA), A PARTIR DE UNA MEZCLA DE ALIMENTACIÓN, CUYO PROCESO COMPRENDE LA PASADA DE LA MEZCLA DE ALIMENTACIÓN A TRAVÉS DE UNA O MÁS COLUMNAS DE CROMATOGRÁFICAS CONTENIENDO, COMO ELUYENTE, UN SOLVENTE ORGÁNICO ACUOSO, DONDE LA TEMPERATURA DE AL MENOS UNA DE LAS COLUMNAS CROMATOGRÁFICAS, A TRAVÉS DE LAS CUALES ES PASADA LA MEZCLA DE ALIMENTACIÓN, ES MÁS ALTA QUE LA TEMPERATURA AMBIENTE.        
CL2013003797A 2011-07-06 2013-12-30 Proceso de separacion cromatografico para recuperar un producto de acido graso poliinsaturado (pufa) que comprende pasar la mezcla de alimentacion a traves de columnas cromatograficas con eluyente solvente organico acuoso y aplicar temperatura controlada; uso de dichas columnas calentadas; y producto pufa. CL2013003797A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1111594.6A GB201111594D0 (en) 2011-07-06 2011-07-06 New improved process

Publications (1)

Publication Number Publication Date
CL2013003797A1 true CL2013003797A1 (es) 2014-07-04

Family

ID=44544340

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003797A CL2013003797A1 (es) 2011-07-06 2013-12-30 Proceso de separacion cromatografico para recuperar un producto de acido graso poliinsaturado (pufa) que comprende pasar la mezcla de alimentacion a traves de columnas cromatograficas con eluyente solvente organico acuoso y aplicar temperatura controlada; uso de dichas columnas calentadas; y producto pufa.

Country Status (17)

Country Link
US (2) US9347020B2 (es)
EP (3) EP3906983B1 (es)
JP (2) JP6223330B2 (es)
KR (2) KR20180033599A (es)
CN (2) CN107233749B (es)
AU (1) AU2012280066B2 (es)
BR (1) BR112014000133B1 (es)
CA (1) CA2815298C (es)
CL (1) CL2013003797A1 (es)
DK (1) DK2613859T3 (es)
ES (3) ES2641536T3 (es)
GB (1) GB201111594D0 (es)
HU (1) HUE036636T2 (es)
NO (1) NO2613859T3 (es)
PE (1) PE20141474A1 (es)
PL (1) PL2613859T3 (es)
WO (1) WO2013005047A1 (es)

Families Citing this family (13)

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RU2014146265A (ru) 2009-12-30 2015-07-10 Басф Фарма (Калланиш) Лимитед Способ хроматографического разделения с псевдодвижущимся слоем
GB201111591D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Further new process
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
GB201111589D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New modified process
GB201111594D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New improved process
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
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JP6303017B2 (ja) 2014-01-07 2018-03-28 ノヴァセプ プロセスＮｏｖａｓｅｐ Ｐｒｏｃｅｓｓ 芳香族アミノ酸を精製する方法
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CA3238072A1 (en) 2021-12-17 2023-06-22 Basf Se Chromatographic separation process for efficient purification of polyunsaturated fatty acids

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EP2613859A1 (en) 2013-07-17
HUE036636T2 (hu) 2018-07-30
CN103826715A (zh) 2014-05-28
EP2613859B1 (en) 2017-08-23
KR101843223B1 (ko) 2018-03-28
DK2613859T3 (en) 2017-10-09
US9771542B2 (en) 2017-09-26
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