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CL2013003556A1 - Compuestos derivados de ftalazinona-pirrolo[3,2-d]pirimidin-carboxamida, inhibidoers de fosfodiesterasa tipo 4 y tipo 5; composcin farmaceutica que o comprende, combinacion fija, no fija y kit, uso del compuesto en la preparacion de un medicamento para trata enfermedaes de las vias respiratorias - Google Patents

Compuestos derivados de ftalazinona-pirrolo[3,2-d]pirimidin-carboxamida, inhibidoers de fosfodiesterasa tipo 4 y tipo 5; composcin farmaceutica que o comprende, combinacion fija, no fija y kit, uso del compuesto en la preparacion de un medicamento para trata enfermedaes de las vias respiratorias

Info

Publication number
CL2013003556A1
CL2013003556A1 CL2013003556A CL2013003556A CL2013003556A1 CL 2013003556 A1 CL2013003556 A1 CL 2013003556A1 CL 2013003556 A CL2013003556 A CL 2013003556A CL 2013003556 A CL2013003556 A CL 2013003556A CL 2013003556 A1 CL2013003556 A1 CL 2013003556A1
Authority
CL
Chile
Prior art keywords
type
fixed
phthalazinone
pyrrolo
pyrimidine
Prior art date
Application number
CL2013003556A
Other languages
English (en)
Inventor
Thomas Stengel
Thomas Maier
Alexander Mann
Josef Stadlwieser
Dieter Flockerzi
Andreas Pahl
Ewald Benediktus
Manuela Hessmann
Tobias Kanacher
Ragna Hussong
Christof Zitt
Hans Christof Holst
Rolf Peter Hummel
Martin Viertelhaus
Hermann Tenor
Torsten Dunkern
Armin Hatzelmann
Christian Hesslinger
Original Assignee
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44764312&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013003556(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Gmbh filed Critical Takeda Gmbh
Publication of CL2013003556A1 publication Critical patent/CL2013003556A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2013003556A 2011-06-17 2013-12-11 Compuestos derivados de ftalazinona-pirrolo[3,2-d]pirimidin-carboxamida, inhibidoers de fosfodiesterasa tipo 4 y tipo 5; composcin farmaceutica que o comprende, combinacion fija, no fija y kit, uso del compuesto en la preparacion de un medicamento para trata enfermedaes de las vias respiratorias CL2013003556A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11170440 2011-06-17

Publications (1)

Publication Number Publication Date
CL2013003556A1 true CL2013003556A1 (es) 2014-06-13

Family

ID=44764312

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003556A CL2013003556A1 (es) 2011-06-17 2013-12-11 Compuestos derivados de ftalazinona-pirrolo[3,2-d]pirimidin-carboxamida, inhibidoers de fosfodiesterasa tipo 4 y tipo 5; composcin farmaceutica que o comprende, combinacion fija, no fija y kit, uso del compuesto en la preparacion de un medicamento para trata enfermedaes de las vias respiratorias

Country Status (22)

Country Link
US (2) US20140112945A1 (es)
EP (1) EP2721030B1 (es)
JP (1) JP5980318B2 (es)
KR (1) KR20140037195A (es)
CN (1) CN103582644B (es)
AR (1) AR086915A1 (es)
AU (1) AU2012269133A1 (es)
BR (1) BR112013031791A2 (es)
CA (1) CA2837248A1 (es)
CL (1) CL2013003556A1 (es)
CO (1) CO6852074A2 (es)
CR (1) CR20130656A (es)
DO (1) DOP2013000298A (es)
EA (1) EA023713B1 (es)
EC (1) ECSP13013076A (es)
ES (1) ES2564882T3 (es)
MA (1) MA35269B1 (es)
MX (1) MX2013014888A (es)
PE (1) PE20140648A1 (es)
PH (1) PH12013502546A1 (es)
TN (1) TN2013000439A1 (es)
WO (1) WO2012171900A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3209313T3 (pl) 2015-04-09 2019-06-28 Galderma Sa Ekstrakt z Indigo Naturalis i sposób jego wytwarzania
WO2016162488A1 (en) * 2015-04-09 2016-10-13 Galderma Sa Treatment of atopic dermatitis with indigo naturalis or indigo producing plant extract
EP3280428A1 (en) 2015-04-09 2018-02-14 Galderma S.A. Antibacterial indigo naturalis or indigo-producing plant extract and use thereof
JP6749935B2 (ja) 2015-04-09 2020-09-02 ガルデルマ・ソシエテ・アノニム 医薬組成物及びその使用
WO2022006470A1 (en) 2020-07-01 2022-01-06 Vanderbilt University Methods of treatment for a kidney disease

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
ES2060040T5 (es) 1989-05-31 1999-09-16 Fisons Plc Dispositivo y formulacion de inhalacion de medicamento.
GB8921222D0 (en) 1989-09-20 1989-11-08 Riker Laboratories Inc Medicinal aerosol formulations
IE67185B1 (en) 1990-02-02 1996-03-06 Fisons Plc Propellant compositions
DE4003272A1 (de) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
EP0965335B1 (en) 1990-03-23 2003-09-17 Minnesota Mining And Manufacturing Company Metered-dose aerosol formulations
CA2094266C (en) 1990-10-18 1999-06-01 Robert K. Schultz Aerosol formulations of beclomethasone-17,21-dipropionate
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
GB9213874D0 (en) 1992-06-30 1992-08-12 Fisons Plc Process to novel medicament form
GB9306703D0 (en) 1993-03-31 1993-05-26 Fisons Plc Inhalation device
IL111194A (en) 1993-10-08 1998-02-08 Fisons Plc Process for the production of medicament formulations
SK283270B6 (sk) * 1997-01-15 2003-04-01 Altana Pharma Ag Ftalazinóny, farmaceutické prostriedky s ich obsahom a ich použitie
PT1070056E (pt) * 1998-03-14 2004-11-30 Altana Pharma Ag Inibidores de pde iii/iv a base de ftalazinona
EP1102579B1 (de) 1998-08-04 2003-03-19 Jago Research Ag Medizinische aerosolformulierungen
US6397838B1 (en) 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
EP1194244B1 (en) 1999-04-23 2005-12-21 Battelle Memorial Institute Directionally controlled ehd aerosol sprayer
BR0009992A (pt) 1999-04-23 2002-01-08 Battelle Memorial Institute Pulverizador de aerossol eletro-hidrodinâmico, aparelho e processo para administrar um aerossol e processo para produzir e administrar um aerossol
JP2003535850A (ja) * 2000-06-05 2003-12-02 アルタナ ファルマ アクチエンゲゼルシャフト β−２−アドレナリン受容体として効果的な化合物並びにＰＤＥ４−インヒビター
CA2425035A1 (en) 2000-10-09 2002-04-18 3M Innovative Properties Company Medicinal aerosol formulations
HUP0303193A3 (en) * 2001-02-15 2007-08-28 Altana Pharma Ag Phthalayinone-piperidino-derivatives as pde4 inhibitors and pharmaceutical compositions containing them
US7186710B2 (en) 2001-04-25 2007-03-06 Altana Pharma Ag Phthalazinones
CA2494613C (en) 2002-08-10 2011-06-28 Altana Pharma Ag Pyrrolidinedione substituted piperidine-phthalazones as pde4 inhibitors
AU2003255376A1 (en) 2002-08-10 2004-03-11 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
EP1556369A1 (en) * 2002-08-10 2005-07-27 ALTANA Pharma AG Pyridazinone-derivatives as pde4 inhibitors
RS20050523A (sr) * 2003-01-14 2007-09-21 Altana Pharma Ag., Pde4 inhibitori za tretman neoplazmi limfocitnih ćelija
EP1720854A1 (en) * 2004-02-04 2006-11-15 Altana Pharma AG Phthalzinone derivatives as pde4 inhibitors
CA2554797C (en) 2004-02-04 2012-09-04 Altana Pharma Ag 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
AR070454A1 (es) * 2008-02-27 2010-04-07 Nycomed Gmbh Pirrolopirimidincarboxamidas y composiciones farmaceuticas que las comprenden
AR077898A1 (es) * 2009-08-26 2011-09-28 Nycomed Gmbh Metilpirrolopirimidincarboxamidas

Also Published As

Publication number Publication date
AR086915A1 (es) 2014-01-29
MA35269B1 (fr) 2014-07-03
EP2721030B1 (en) 2015-12-16
KR20140037195A (ko) 2014-03-26
AU2012269133A1 (en) 2014-01-30
BR112013031791A2 (pt) 2017-01-31
CO6852074A2 (es) 2014-01-30
EA201400001A1 (ru) 2014-05-30
PE20140648A1 (es) 2014-05-30
JP2014517021A (ja) 2014-07-17
JP5980318B2 (ja) 2016-08-31
EA023713B1 (ru) 2016-07-29
WO2012171900A1 (en) 2012-12-20
US20160108049A1 (en) 2016-04-21
PH12013502546A1 (en) 2014-01-27
US20140112945A1 (en) 2014-04-24
CA2837248A1 (en) 2012-12-20
CR20130656A (es) 2014-02-18
CN103582644B (zh) 2016-07-20
TN2013000439A1 (en) 2015-03-30
ES2564882T3 (es) 2016-03-29
EP2721030A1 (en) 2014-04-23
ECSP13013076A (es) 2014-01-31
DOP2013000298A (es) 2014-03-31
CN103582644A (zh) 2014-02-12
MX2013014888A (es) 2014-02-27

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