CL2013002985A1 - Compuestos derivados de aminometilfenilo biciclico, como moduladores del receptor de esfingosina-1-fosfato; composicion farmaceutica que los comprende; y su uso para tratar enfermedades oculares, enfermedades inflamatorias, enfermedades autoinmunes e inmunosupresion, aterosclerosis, enfermedad de alzheimer. - Google Patents
Compuestos derivados de aminometilfenilo biciclico, como moduladores del receptor de esfingosina-1-fosfato; composicion farmaceutica que los comprende; y su uso para tratar enfermedades oculares, enfermedades inflamatorias, enfermedades autoinmunes e inmunosupresion, aterosclerosis, enfermedad de alzheimer.Info
- Publication number
- CL2013002985A1 CL2013002985A1 CL2013002985A CL2013002985A CL2013002985A1 CL 2013002985 A1 CL2013002985 A1 CL 2013002985A1 CL 2013002985 A CL2013002985 A CL 2013002985A CL 2013002985 A CL2013002985 A CL 2013002985A CL 2013002985 A1 CL2013002985 A1 CL 2013002985A1
- Authority
- CL
- Chile
- Prior art keywords
- diseases
- aminomethylphenyl
- sphingosine
- immunosuppression
- atherosclerosis
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title 1
- 201000001320 Atherosclerosis Diseases 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 206010062016 Immunosuppression Diseases 0.000 title 1
- 229940127530 Sphingosine 1-Phosphate Receptor Modulators Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 208000030533 eye disease Diseases 0.000 title 1
- 230000001506 immunosuppresive effect Effects 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
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- C—CHEMISTRY; METALLURGY
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/08—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms with acylated ring nitrogen atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161475352P | 2011-04-14 | 2011-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013002985A1 true CL2013002985A1 (es) | 2014-06-13 |
Family
ID=45998680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013002985A CL2013002985A1 (es) | 2011-04-14 | 2013-10-14 | Compuestos derivados de aminometilfenilo biciclico, como moduladores del receptor de esfingosina-1-fosfato; composicion farmaceutica que los comprende; y su uso para tratar enfermedades oculares, enfermedades inflamatorias, enfermedades autoinmunes e inmunosupresion, aterosclerosis, enfermedad de alzheimer. |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US8716267B2 (es) |
| EP (2) | EP2697212B1 (es) |
| JP (1) | JP2014511878A (es) |
| KR (1) | KR20140048874A (es) |
| CN (1) | CN103619828A (es) |
| AU (2) | AU2012242827A1 (es) |
| BR (1) | BR112013026507A2 (es) |
| CA (2) | CA2833313A1 (es) |
| CL (1) | CL2013002985A1 (es) |
| IL (1) | IL228850A0 (es) |
| MX (1) | MX2013011979A (es) |
| RU (1) | RU2013150173A (es) |
| SG (1) | SG194184A1 (es) |
| WO (2) | WO2012142288A1 (es) |
| ZA (1) | ZA201307796B (es) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013026507A2 (pt) * | 2011-04-14 | 2016-12-27 | Allergan Inc | derivados de metil amina fenil bicíclicos como moduladores dos receptores de esfinfgosina-1 fosfato |
| CN112851562A (zh) * | 2021-01-22 | 2021-05-28 | 烟台显华化工科技有限公司 | 一种芳香环液晶化合物及其液晶组合物和应用 |
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| EP1575964B1 (en) * | 2002-01-18 | 2009-11-11 | Merck & Co., Inc. | N-(benzyl)aminoalkyl carboxylate, phosphinates, phosphonates and tetrazoles as edg receptor agonists |
| EP1622866B1 (en) * | 2003-04-30 | 2012-07-25 | Novartis AG | Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators |
| EP2644195A1 (en) * | 2003-05-19 | 2013-10-02 | Irm Llc | Immunosuppressant Compounds and Compositions |
| PL1638551T3 (pl) * | 2003-05-19 | 2012-05-31 | Irm Llc | Związki i kompozycje immunosupresyjne |
| CA2824106A1 (en) * | 2003-08-29 | 2005-03-10 | Ono Pharmaceutical Co., Ltd. | Compound capable of binding s1p receptor and pharmaceutical use thereof |
| CA2591399C (en) * | 2004-12-13 | 2014-05-20 | Ono Pharmaceutical Co., Ltd. | Aminocarboxylic acid derivative and medicinal use thereof |
| KR20080024533A (ko) * | 2005-06-24 | 2008-03-18 | 액테리온 파마슈티칼 리미티드 | 신규한 티오펜 유도체 |
| EP2017257B1 (en) * | 2006-04-28 | 2014-08-06 | Mitsubishi Tanabe Pharma Corporation | 2-aminobutanol compound and use thereof for medical purposes |
| JP2009269819A (ja) * | 2006-08-25 | 2009-11-19 | Asahi Kasei Pharma Kk | アミン化合物 |
| WO2008097819A2 (en) * | 2007-02-05 | 2008-08-14 | Smithkline Beecham Corporation | Chemical compounds |
| MX2010001446A (es) * | 2007-08-08 | 2010-03-01 | Merck Serono Sa | Derivados de 6-amino-pirimidina-4-carboxamida y compuestos relacionados que se enlazan a los receptores para esfingosina 1-fosfato (s1p) para el tratamiento de esclerosis multiple. |
| JP2010536791A (ja) * | 2007-08-15 | 2010-12-02 | ユニバーシティ オブ バージニア パテント ファンデーション | 二環式スフィンゴシン1−リン酸アナログ |
| AU2009323259A1 (en) * | 2008-12-05 | 2011-06-23 | Astellas Pharma Inc. | 2H-chromene compound and derivative thereof |
| CN102712607B (zh) * | 2009-11-24 | 2016-06-22 | 阿勒根公司 | 作为具有治疗效用的受体调节剂的化合物 |
| AU2011332155A1 (en) * | 2010-11-23 | 2013-07-04 | Allergan, Inc. | Novel phosphonic acids as S1P receptor modulators |
| CA2833305A1 (en) * | 2011-04-14 | 2012-10-18 | Allergan, Inc. | Phenyl bicyclic methyl azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| BR112013026507A2 (pt) * | 2011-04-14 | 2016-12-27 | Allergan Inc | derivados de metil amina fenil bicíclicos como moduladores dos receptores de esfinfgosina-1 fosfato |
| CA2833545A1 (en) * | 2011-04-18 | 2012-10-26 | Allergan, Inc. | Substituted bicyclic methyl amine derivatives as sphingosine-1 phosphate receptors modulators |
-
2012
- 2012-04-12 BR BR112013026507A patent/BR112013026507A2/pt not_active IP Right Cessation
- 2012-04-12 SG SG2013076609A patent/SG194184A1/en unknown
- 2012-04-12 KR KR1020137030126A patent/KR20140048874A/ko not_active Withdrawn
- 2012-04-12 AU AU2012242827A patent/AU2012242827A1/en not_active Abandoned
- 2012-04-12 WO PCT/US2012/033321 patent/WO2012142288A1/en not_active Ceased
- 2012-04-12 MX MX2013011979A patent/MX2013011979A/es not_active Application Discontinuation
- 2012-04-12 CN CN201280028552.2A patent/CN103619828A/zh active Pending
- 2012-04-12 CA CA2833313A patent/CA2833313A1/en not_active Abandoned
- 2012-04-12 JP JP2014505281A patent/JP2014511878A/ja active Pending
- 2012-04-12 EP EP12716170.1A patent/EP2697212B1/en not_active Not-in-force
- 2012-04-12 RU RU2013150173/04A patent/RU2013150173A/ru not_active Application Discontinuation
- 2012-04-13 US US13/446,575 patent/US8716267B2/en not_active Expired - Fee Related
- 2012-04-13 EP EP12717536.2A patent/EP2696877A1/en not_active Withdrawn
- 2012-04-13 CA CA2833255A patent/CA2833255A1/en not_active Abandoned
- 2012-04-13 AU AU2012242652A patent/AU2012242652A1/en not_active Abandoned
- 2012-04-13 US US13/446,352 patent/US8541582B2/en not_active Expired - Fee Related
- 2012-04-13 WO PCT/US2012/033467 patent/WO2012142377A1/en not_active Ceased
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2013
- 2013-07-08 US US13/936,891 patent/US8653050B2/en not_active Expired - Fee Related
- 2013-10-13 IL IL228850A patent/IL228850A0/en unknown
- 2013-10-14 CL CL2013002985A patent/CL2013002985A1/es unknown
- 2013-10-18 ZA ZA2013/07796A patent/ZA201307796B/en unknown
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2014
- 2014-03-20 US US14/221,093 patent/US8946195B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014511878A (ja) | 2014-05-19 |
| US8946195B2 (en) | 2015-02-03 |
| EP2697212B1 (en) | 2015-09-09 |
| CN103619828A (zh) | 2014-03-05 |
| CA2833255A1 (en) | 2012-10-18 |
| AU2012242652A1 (en) | 2013-10-31 |
| CA2833313A1 (en) | 2012-10-18 |
| US20140206652A1 (en) | 2014-07-24 |
| US8716267B2 (en) | 2014-05-06 |
| KR20140048874A (ko) | 2014-04-24 |
| EP2696877A1 (en) | 2014-02-19 |
| SG194184A1 (en) | 2013-11-29 |
| US8653050B2 (en) | 2014-02-18 |
| IL228850A0 (en) | 2013-12-31 |
| WO2012142377A1 (en) | 2012-10-18 |
| RU2013150173A (ru) | 2015-05-20 |
| ZA201307796B (en) | 2014-07-30 |
| BR112013026507A2 (pt) | 2016-12-27 |
| US20120264716A1 (en) | 2012-10-18 |
| US20120264718A1 (en) | 2012-10-18 |
| EP2697212A1 (en) | 2014-02-19 |
| MX2013011979A (es) | 2014-02-06 |
| US20130338108A1 (en) | 2013-12-19 |
| US8541582B2 (en) | 2013-09-24 |
| AU2012242827A1 (en) | 2013-10-31 |
| WO2012142288A1 (en) | 2012-10-18 |
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