CL2013001403A1 - Anticuerpo monoclonal anti-ccl20 o un fragmento de unión del mismo; molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; composicion que lo comprende; y su uso. - Google Patents
Anticuerpo monoclonal anti-ccl20 o un fragmento de unión del mismo; molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; composicion que lo comprende; y su uso.Info
- Publication number
- CL2013001403A1 CL2013001403A1 CL2013001403A CL2013001403A CL2013001403A1 CL 2013001403 A1 CL2013001403 A1 CL 2013001403A1 CL 2013001403 A CL2013001403 A CL 2013001403A CL 2013001403 A CL2013001403 A CL 2013001403A CL 2013001403 A1 CL2013001403 A1 CL 2013001403A1
- Authority
- CL
- Chile
- Prior art keywords
- encodes
- vector
- nucleic acid
- composition
- production
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/521—Chemokines
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41561410P | 2010-11-19 | 2010-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013001403A1 true CL2013001403A1 (es) | 2014-08-08 |
Family
ID=46084688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013001403A CL2013001403A1 (es) | 2010-11-19 | 2013-05-17 | Anticuerpo monoclonal anti-ccl20 o un fragmento de unión del mismo; molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; composicion que lo comprende; y su uso. |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US8491901B2 (es) |
| EP (1) | EP2640744A4 (es) |
| JP (3) | JP5996549B2 (es) |
| KR (1) | KR101919170B1 (es) |
| CN (1) | CN103874707B (es) |
| AR (1) | AR084141A1 (es) |
| AU (2) | AU2011329647B2 (es) |
| BR (1) | BR112013012396A2 (es) |
| CA (1) | CA2818548A1 (es) |
| CL (1) | CL2013001403A1 (es) |
| CO (1) | CO6761352A2 (es) |
| CR (1) | CR20130228A (es) |
| DO (1) | DOP2013000111A (es) |
| EA (1) | EA029419B1 (es) |
| IL (1) | IL226383B (es) |
| MA (1) | MA34738B1 (es) |
| MX (1) | MX361929B (es) |
| NZ (1) | NZ611269A (es) |
| PE (2) | PE20180249A1 (es) |
| PH (1) | PH12013500990A1 (es) |
| SG (2) | SG10201509499RA (es) |
| TW (1) | TWI589587B (es) |
| UA (1) | UA114077C2 (es) |
| WO (1) | WO2012068540A2 (es) |
| ZA (3) | ZA201303571B (es) |
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| PE20180249A1 (es) * | 2010-11-19 | 2018-02-02 | Eisai Randd Man Co Ltd | Anticuerpos neutralizadores anti-ccl20 |
| AU2013221585B2 (en) | 2012-02-17 | 2017-03-30 | Seagen Inc. | Antibodies to integrin alphavbeta6 and use of same to treat cancer |
| WO2014062659A2 (en) * | 2012-10-15 | 2014-04-24 | Oncomed Pharmaceuticals, Inc. | Methods of treating ocular diseases |
| EP3689325A1 (en) | 2014-04-08 | 2020-08-05 | Boston Pharmaceuticals Inc. | Binding molecules specific for il-21 and uses thereof |
| MX2016015181A (es) | 2014-05-21 | 2017-05-25 | Pfizer | Combinacion de un anticuerpo del receptor 4 de quimiocina anti-cc y un agonista de 4-1 bb para el tratamiento del cancer. |
| MA41480A (fr) * | 2014-10-17 | 2017-12-19 | Glenmark Pharmaceuticals Sa | Anticorps qui se lient au ccr6 et leurs utilisations |
| US10647766B2 (en) * | 2014-12-17 | 2020-05-12 | Cancer Research Technology Limited | Anti-CXCL12 antibody molecules and their uses |
| US11571462B2 (en) | 2015-06-03 | 2023-02-07 | The Medical College Of Wisconsin, Inc. | Engineered CCL20 locked dimer polypeptide |
| EP3666282A1 (en) | 2015-06-03 | 2020-06-17 | The Medical College of Wisconsin, Inc. | An engineered ccl20 locked dimer polypeptide |
| KR20180027568A (ko) * | 2015-07-14 | 2018-03-14 | 메디뮨 엘엘씨 | 암을 치료하기 위한 조성물 및 방법 |
| WO2017064564A2 (en) * | 2015-10-16 | 2017-04-20 | Glaxosmithkline Intellectual Property Limited | Therapeutic regimens for treating psoriatic arthritis with an anti-ccl20 antibody |
| BR112018014908A2 (pt) * | 2016-01-21 | 2018-12-18 | The Scripps Research Institute | vacina de opioide sintético |
| CA3010224A1 (en) | 2016-01-22 | 2017-07-27 | Merck Sharp & Dohme Corp. | Anti-coagulation factor xi antibodies |
| AU2017286432B2 (en) | 2016-06-14 | 2020-09-24 | Adimab, Llc | Anti-coagulation factor XI antibodies |
| WO2018088877A2 (ko) * | 2016-11-14 | 2018-05-17 | 다이노나(주) | CD66c에 특이적으로 결합하는 항체 및 그의 용도 |
| FR3072779A1 (fr) * | 2017-10-19 | 2019-04-26 | Sinnovial | Procede d'estimation de l'efficacite d'un modulateur de la costimulation des lymphocytes t contre la polyarthrite rhumatoide apres reponse inadequate a une biotherapie |
| WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
| CA3082365A1 (en) | 2017-11-09 | 2019-05-16 | Pinteon Therapeutics Inc. | Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies |
| WO2020185952A1 (en) * | 2019-03-11 | 2020-09-17 | xCella Biosciences, Inc. | Cd27-binding antibodies and uses thereof |
| US11827709B2 (en) * | 2019-12-05 | 2023-11-28 | Seagen Inc. | Anti-AVB6 antibodies and antibody-drug conjugates |
| CN113087795B (zh) * | 2019-12-23 | 2025-06-10 | 上海普铭生物科技有限公司 | 针对趋化因子cx3cl1的抗体及其应用 |
| US12129302B2 (en) | 2021-08-25 | 2024-10-29 | Ibio, Inc. | Anti-CD-25 antibody |
| CN117209603B (zh) * | 2021-12-02 | 2024-02-27 | 北京东方百泰生物科技股份有限公司 | 一种抗tslp的单克隆抗体、其抗原结合片段及其应用 |
| CN120518761B (zh) * | 2023-06-05 | 2025-12-26 | 北京东方百泰生物科技股份有限公司 | 一种结合il-11的抗体、其抗原结合片段及应用 |
| CN119139478A (zh) * | 2024-10-11 | 2024-12-17 | 首都医科大学附属北京胸科医院 | 一种治疗anxa6+egfr突变的肺腺癌的组合物 |
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