[go: up one dir, main page]

CL2012001749A1 - Metodos para purificar una composicion de rebaudiosido a, que comprende combinar una composicion de baja pureza con un solvente organico que opcionalmente contiene agua, cristalizar la solucion en un solo paso asi obtener una mezcla de glicosidos de esteviol de pureza mayor al 95%, que contiene rebausiosido a en cantidad mayor al 85%. - Google Patents

Metodos para purificar una composicion de rebaudiosido a, que comprende combinar una composicion de baja pureza con un solvente organico que opcionalmente contiene agua, cristalizar la solucion en un solo paso asi obtener una mezcla de glicosidos de esteviol de pureza mayor al 95%, que contiene rebausiosido a en cantidad mayor al 85%.

Info

Publication number
CL2012001749A1
CL2012001749A1 CL2012001749A CL2012001749A CL2012001749A1 CL 2012001749 A1 CL2012001749 A1 CL 2012001749A1 CL 2012001749 A CL2012001749 A CL 2012001749A CL 2012001749 A CL2012001749 A CL 2012001749A CL 2012001749 A1 CL2012001749 A1 CL 2012001749A1
Authority
CL
Chile
Prior art keywords
composition
purity
crystallizing
rebaudioside
organic solvent
Prior art date
Application number
CL2012001749A
Other languages
English (en)
Inventor
Indra Prakash
Mani Upreti
Grant E Dubois
George A King
Anish Mehta
Original Assignee
Coca Cola Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43649381&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2012001749(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Coca Cola Co filed Critical Coca Cola Co
Publication of CL2012001749A1 publication Critical patent/CL2012001749A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/36—Terpene glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)

Abstract

Métodos para purificar una composición de rebaudiósido A de baja pureza que comprende combinar una composición de rebaudiósido de baja pureza y un solvente orgánico y cristalizar dicha solución.
CL2012001749A 2009-12-31 2012-06-26 Metodos para purificar una composicion de rebaudiosido a, que comprende combinar una composicion de baja pureza con un solvente organico que opcionalmente contiene agua, cristalizar la solucion en un solo paso asi obtener una mezcla de glicosidos de esteviol de pureza mayor al 95%, que contiene rebausiosido a en cantidad mayor al 85%. CL2012001749A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/650,637 US9012626B2 (en) 2006-06-19 2009-12-31 Rebaudioside a composition and method for purifying rebaudioside a

Publications (1)

Publication Number Publication Date
CL2012001749A1 true CL2012001749A1 (es) 2013-05-03

Family

ID=43649381

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012001749A CL2012001749A1 (es) 2009-12-31 2012-06-26 Metodos para purificar una composicion de rebaudiosido a, que comprende combinar una composicion de baja pureza con un solvente organico que opcionalmente contiene agua, cristalizar la solucion en un solo paso asi obtener una mezcla de glicosidos de esteviol de pureza mayor al 95%, que contiene rebausiosido a en cantidad mayor al 85%.

Country Status (16)

Country Link
US (1) US9012626B2 (es)
EP (1) EP2519534B1 (es)
JP (1) JP2013516423A (es)
KR (1) KR20120116460A (es)
CN (2) CN106167509A (es)
AU (1) AU2010339459B2 (es)
BR (1) BR112012016387A2 (es)
CA (1) CA2784810C (es)
CL (1) CL2012001749A1 (es)
DK (1) DK2519534T3 (es)
IN (1) IN2012DN05893A (es)
MX (1) MX345164B (es)
PH (1) PH12012501318A1 (es)
RU (1) RU2591852C2 (es)
WO (1) WO2011082288A1 (es)
ZA (1) ZA201204841B (es)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8257948B1 (en) 2011-02-17 2012-09-04 Purecircle Usa Method of preparing alpha-glucosyl Stevia composition
US9386797B2 (en) 2011-02-17 2016-07-12 Purecircle Sdn Bhd Glucosyl stevia composition
US9392799B2 (en) 2011-02-17 2016-07-19 Purecircle Sdn Bhd Glucosyl stevia composition
US8318459B2 (en) 2011-02-17 2012-11-27 Purecircle Usa Glucosyl stevia composition
US9107436B2 (en) 2011-02-17 2015-08-18 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
US8791253B2 (en) * 2006-06-19 2014-07-29 The Coca-Cola Company Rebaudioside A composition and method for purifying rebaudioside A
US9012626B2 (en) * 2006-06-19 2015-04-21 The Coca-Cola Company Rebaudioside a composition and method for purifying rebaudioside a
US8030481B2 (en) * 2007-05-21 2011-10-04 The Coca-Cola Company Stevioside polymorphic and amorphous forms, methods for their formulation, and uses
PL2482676T3 (pl) * 2009-06-16 2015-03-31 Epc Beijing Natural Products Co Ltd Zmniejszanie lub eliminowanie posmaku w słodziku przy użyciu rebaudiozydu D
US20110111115A1 (en) * 2009-11-06 2011-05-12 Jingang Shi Rebaudioside a polymorphs and methods to prepare them
US10696706B2 (en) 2010-03-12 2020-06-30 Purecircle Usa Inc. Methods of preparing steviol glycosides and uses of the same
US20150344512A1 (en) 2011-12-19 2015-12-03 Purecircle Usa Inc. Methods of purifying steviol glycosides and uses of the same
EP4108668A1 (en) 2010-03-12 2022-12-28 PureCircle USA Inc. High-purity steviol glycosides
WO2012006728A1 (en) * 2010-07-15 2012-01-19 Glg Life Tech Corporation Sweetener compositions and methods of making same
US9578895B2 (en) 2010-08-23 2017-02-28 Epc (Beijing) Natural Products Co., Ltd. Rebaudioside A and stevioside compositions
US20120083593A1 (en) * 2010-10-01 2012-04-05 Shanghai Yongyou Bioscience Inc. Separation and Purification of Stevioside and Rebaudioside A
WO2012068457A1 (en) 2010-11-19 2012-05-24 Cargill, Incorporated Method for the enrichment of rebaudioside b and/or rebaudioside d in stevia-derived glycoside compositions using adsorb-desorb chromatography with a macroporous neutral adsorbent resin
MX370544B (es) * 2010-12-13 2019-12-17 Cargill Inc Mezclas de glucosidos.
US9510611B2 (en) 2010-12-13 2016-12-06 Purecircle Sdn Bhd Stevia composition to improve sweetness and flavor profile
US9090647B2 (en) 2010-12-13 2015-07-28 Cargill, Incorporated Crystalline forms of rebaudioside B
US9029426B2 (en) 2010-12-13 2015-05-12 Purecircle Sdn Bhd Highly soluble Rebaudioside D
US10362797B2 (en) 2011-02-10 2019-07-30 Purecircle Sdn Bhd Stevia composition
US20130337143A1 (en) * 2011-02-10 2013-12-19 Siddhartha PURKAYASTHA Stevia composition
WO2012109585A1 (en) * 2011-02-10 2012-08-16 Purecircle Usa Stevia composition
US11690391B2 (en) 2011-02-17 2023-07-04 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
US9474296B2 (en) 2011-02-17 2016-10-25 Purecircle Sdn Bhd Glucosyl stevia composition
US9603373B2 (en) 2011-02-17 2017-03-28 Purecircle Sdn Bhd Glucosyl stevia composition
US9795156B2 (en) 2011-03-17 2017-10-24 E.P.C (Beijing) Plant Pharmaceutical Technology Co., Ltd Rebaudioside B and derivatives
US9894922B2 (en) 2011-05-18 2018-02-20 Purecircle Sdn Bhd Glucosyl rebaudioside C
AR087158A1 (es) 2011-06-20 2014-02-26 Gen Biscuit Masita en capas saludable
US9771434B2 (en) 2011-06-23 2017-09-26 Purecircle Sdn Bhd Products from stevia rebaudiana
CN103974628B (zh) 2012-05-22 2019-04-05 谱赛科有限责任公司 高纯度的甜菊醇糖苷
US9752174B2 (en) 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
CN103059079A (zh) * 2012-12-31 2013-04-24 天津北洋百川生物技术有限公司 Ra97甜菊糖甙的不定形晶型及其制备方法
WO2014172055A2 (en) * 2013-03-15 2014-10-23 The Coca-Cola Company Novel glucosyl steviol glycosides, their compositions and their purification
EP3714699B1 (en) 2013-06-07 2024-12-18 PureCircle USA Inc. Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
US10952458B2 (en) 2013-06-07 2021-03-23 Purecircle Usa Inc Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
CN103739639B (zh) * 2014-01-30 2016-10-19 诸城市浩天药业有限公司 一种甜菊糖a苷晶体及其制备方法和用途
CN103739640B (zh) * 2014-01-30 2016-08-17 诸城市浩天药业有限公司 一种甜菊糖a苷晶体及其制备方法和用途
US10264811B2 (en) 2014-05-19 2019-04-23 Epc Natural Products Co., Ltd. Stevia sweetener with improved solubility
US10357052B2 (en) 2014-06-16 2019-07-23 Sweet Green Fields USA LLC Rebaudioside A and stevioside with improved solubilities
US10485256B2 (en) 2014-06-20 2019-11-26 Sweet Green Fields International Co., Limited Stevia sweetener with improved solubility with a cyclodextrin
US11230567B2 (en) 2014-09-02 2022-01-25 Purecircle Usa Inc. Stevia extracts enriched in rebaudioside D, E, N and/or O and process for the preparation thereof
CN104231017A (zh) * 2014-09-28 2014-12-24 晨光生物科技集团股份有限公司 提高甜菊糖母液糖品质的方法
CN108522291B (zh) * 2015-01-23 2022-01-04 谱赛科美国公司 利用甜叶菊新品种814011谱星3号制备高rm含量甜菊糖苷的方法
CN107613785A (zh) 2015-05-20 2018-01-19 嘉吉公司 糖苷组合物
CN105063136B (zh) * 2015-08-11 2018-04-24 南京师范大学 一种利用嗜松青霉转化甜菊糖制备杜尔可苷a的方法
CN108495559A (zh) 2015-10-26 2018-09-04 谱赛科美国股份有限公司 甜菊醇糖苷组合物
RU2764635C2 (ru) 2015-12-15 2022-01-19 ПЬЮРСЁРКЛ ЮЭсЭй ИНК. Композиция стевиол гликозида
CN105693791B (zh) * 2016-03-24 2018-12-28 诸城市浩天药业有限公司 甜菊双糖苷晶型a、其制备方法、食品组合物及应用
WO2017218072A1 (en) * 2016-06-14 2017-12-21 Purecircle Usa Inc. Steviol glycosides compositions, production methods and uses
BR112019002432A2 (pt) 2016-08-09 2019-06-04 Dsm Ip Assets Bv cristalização de glicosídeos de esteviol
MY202890A (en) 2016-08-09 2024-05-28 Dsm Ip Assets Bv Crystallization of steviol glycosides
CN108680695A (zh) * 2018-05-14 2018-10-19 上海药明生物技术有限公司 糖苷结构类表面活性剂的定性定量检测方法
CN109645432A (zh) * 2019-02-20 2019-04-19 史迪威生物科技（苏州）有限公司 一种结晶法制备甜菊糖型餐桌糖方法
CA3209929A1 (en) 2021-03-01 2022-09-09 Erin EVANS Xylosylated steviol glycosides and enzymatic methods for production
CN113461746A (zh) * 2021-08-11 2021-10-01 郑然� 高纯度甜菊糖苷ra的精制方法

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10562A (en) * 1854-02-28 Improvement in scythe-fastenings
US10563A (en) * 1854-02-28 Machine foe
US10564A (en) * 1854-02-28 Improvement in salt-kilns
US3723410A (en) 1970-12-01 1973-03-27 Amazon Natural Drug Co Method of producing stevioside
JPS51142570A (en) 1975-06-04 1976-12-08 Morita Kagaku Kogyo Method of imparting sweetness to food or pharmaceutical agent
JPS5262300A (en) 1975-11-13 1977-05-23 Ajinomoto Co Inc Isolation of bibaudioside-a by crystallization
US4206222A (en) 1977-06-23 1980-06-03 Societe Civile Particuliere De Brevets Suffren Method for preparing a substance having properties against collagen diseases and products obtained
US4188390A (en) 1977-11-05 1980-02-12 Pfizer Inc. Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
US4219571A (en) 1978-06-15 1980-08-26 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for producing a sweetener
JPS5523756A (en) 1978-08-07 1980-02-20 Tokyo Shibaura Electric Co Controller
JPS56121455A (en) 1980-02-27 1981-09-24 Ajinomoto Co Inc Separation of stevioside and rebaudioside a by crystallization
JPS56121453A (en) 1980-02-27 1981-09-24 Ajinomoto Co Inc Separation of stevioside and rebaudioside a
DE3132656C2 (de) 1980-08-19 1986-09-04 Terumo Corp., Tokio/Tokyo Extrakt aus der Rinde des Nim-Baumes (Melia azadirachta) mit antineoplastischer Wirkung
US4454290A (en) 1980-09-22 1984-06-12 Dynapol Stevioside analogs
US4332830A (en) 1980-09-22 1982-06-01 Dynapol Sweetening with stevioside analogs
US4381402A (en) 1980-09-22 1983-04-26 Dynapol Steviol compounds
JPS5846310B2 (ja) 1980-11-19 1983-10-15 丸善化成株式会社 ステビア中の主要甘味成分を単離する方法
US4361697A (en) 1981-05-21 1982-11-30 F. K. Suzuki International, Inc. Extraction, separation and recovery of diterpene glycosides from Stevia rebaudiana plants
US4353889A (en) 1981-06-11 1982-10-12 Dynapol Rebaudioside analogs
US4402990A (en) 1981-08-26 1983-09-06 Dynapol Steviolmonoside analogs
US4404367A (en) 1981-08-26 1983-09-13 Dynapol Glucosubstituented diterpenoid sweeteners
JPS58149697A (ja) 1982-02-27 1983-09-06 Dainippon Ink & Chem Inc β−１，３グリコシルステビオシドの製造方法
JPS5971662A (ja) 1982-06-10 1984-04-23 Ikeda Touka Kogyo Kk 甘味料の製法
JPS59120073A (ja) 1982-12-28 1984-07-11 Ikeda Touka Kogyo Kk 甘味料及びその製造法
JPS6027360A (ja) 1983-07-25 1985-02-12 Kiyo Kondo 甘味料の味質改善法
JPS6037950A (ja) 1983-08-12 1985-02-27 Sanyo Kokusaku Pulp Co Ltd ステビア甘味料の味質改善法
US4599403A (en) 1985-10-07 1986-07-08 Harold Levy Method for recovery of stevioside
JPH0679547B2 (ja) 1985-10-16 1994-10-12 大日本インキ化学工業株式会社 ステビア甘味料及びその製造方法
DE3810681A1 (de) 1988-03-29 1989-10-12 Udo Kienle Verfahren zur herstellung eines natuerlichen suessungsmittels auf der basis von stevia rebaudiana und seine verwendung
US5530106A (en) 1993-03-12 1996-06-25 Mcneil-Ppc, Inc. Recovery of sucralose intermediates
USPP10562P (en) 1996-05-29 1998-08-18 Royal-Sweet International Technologies Ltd. Part. Stevia plant named `RSIT 94-1306`
USPP10563P (en) 1996-05-29 1998-08-18 Royal-Sweet International Technologies Ltd. Part. Stevia plant named `RSIT 95-166-13`
USPP10564P (en) 1996-05-29 1998-08-18 Royal-Sweet International Technologies Ltd. Stevia plant named `RSIT 94-751`
US5962678A (en) 1996-09-13 1999-10-05 Alberta Research Council Method of extracting selected sweet glycosides from the Stevia rebaudiana plant
US5972120A (en) 1997-07-19 1999-10-26 National Research Council Of Canada Extraction of sweet compounds from Stevia rebaudiana Bertoni
US6255557B1 (en) 1998-03-31 2001-07-03 Her Majesty The Queen In Right Of Canada As Represented By The Ministerof Agriculture And Agri-Food Canada Stevia rebaudiana with altered steviol glycoside composition
BE1012249A3 (nl) 1998-10-27 2000-08-01 Brouwers Louis Jean Hilda Zoetmaker.
AU1628700A (en) 1998-11-20 2000-06-13 Nutrasweet Company, The Amorphous N-(N-(3,3-dimethylbutyl)-l-alpha-aspartyl)-l-phenylalanine 1-methyl ester
WO2000032621A1 (en) 1998-11-25 2000-06-08 The Nutrasweet Company PROCESS FOR PURIFICATION OF N- [N-(3,3-DIMETHYLBUTYL) -L-α-ASPARTYL] -L-PHENYLALANINE 1-METHYL ESTER
AU1832500A (en) 1998-11-25 2000-06-19 Nutrasweet Company, The Purification of N-(N-(3,3-dimethylbutyl)-l-alpha-aspartyl)-l-phenylalanine 1-methyl ester via crystallization
WO2000052019A2 (en) 1999-03-03 2000-09-08 The Nutrasweet Company Crystallization products of neotame and methods for producing same
CA2278083A1 (en) 1999-07-20 2001-01-20 James Kenneth Laidler Method of extracting selected sweet glycosides from the stevia rebaudiana plant
US6784309B2 (en) 1999-07-28 2004-08-31 The Nutrasweet Company Method for the purification of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US7306815B2 (en) 2000-08-31 2007-12-11 Phenolics, Llc Compositions enriched in phenolic compounds and methods for producing the same
AU2691802A (en) 2000-11-17 2002-05-27 Mcneil Ppc Inc Improved sucralose composition and process for its preparation
KR100858768B1 (ko) 2001-06-21 2008-09-16 교와 핫꼬 고교 가부시끼가이샤 식물체 분말 함유 식물 추출물의 제조 방법
KR100851610B1 (ko) 2001-09-21 2008-08-12 디아이씨 가부시끼가이샤 감미료 및 그 제조 방법
US6998480B2 (en) 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US7049435B2 (en) 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose
US20040030124A1 (en) 2002-08-06 2004-02-12 Catani Steven J. Process for recovering chlorosucrose compounds
WO2006038221A1 (en) 2004-10-04 2006-04-13 Council Of Scientific And Industrial Research Process for production of steviosides from stevia rebaudiana bertoni
US7923552B2 (en) 2004-10-18 2011-04-12 SGF Holdings, LLC High yield method of producing pure rebaudioside A
US7838044B2 (en) 2004-12-21 2010-11-23 Purecircle Sdn Bhd Extraction, separation and modification of sweet glycosides from the Stevia rebaudiana plant
US20060142555A1 (en) 2004-12-23 2006-06-29 Council Of Scientific And Industrial Research Process for production of steviosides from stevia rebaudiana bertoni
US7807206B2 (en) 2005-10-11 2010-10-05 Purecircle Sdn Bhd Sweetner and use
US7862845B2 (en) 2005-10-11 2011-01-04 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US8956677B2 (en) 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
US8435588B2 (en) 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith
US20070116800A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US20070116820A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Edible gel compositions comprising high-potency sweeteners
US20070116822A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener composition with saponin and compositions sweetened therewith
US20070116831A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Dental Composition with High-Potency Sweetener
EP2526783B1 (en) 2005-11-23 2016-10-19 The Coca-Cola Company Natural high-potency sweetener compositions with improved temporal profile and/or flavor profile
US8435587B2 (en) 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
US20070116833A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
US8512789B2 (en) 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US20070116829A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
US20070116836A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith
RU2459434C2 (ru) * 2005-11-23 2012-08-27 Дзе Кока-Кола Компани Композиции натурального интенсивного подсластителя с улучшенным временным параметром и(или) корригирующим параметром, способы их приготовления и их применения
US8524303B2 (en) 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
US8377491B2 (en) 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
US8940350B2 (en) 2005-11-23 2015-01-27 The Coca-Cola Company Cereal compositions comprising high-potency sweeteners
US20070116839A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
US8945652B2 (en) 2005-11-23 2015-02-03 The Coca-Cola Company High-potency sweetener for weight management and compositions sweetened therewith
US8367137B2 (en) 2005-11-23 2013-02-05 The Coca-Cola Company High-potency sweetener composition with fatty acid and compositions sweetened therewith
US8367138B2 (en) 2005-11-23 2013-02-05 The Coca-Cola Company Dairy composition with high-potency sweetener
US9144251B2 (en) 2005-11-23 2015-09-29 The Coca-Cola Company High-potency sweetener composition with mineral and compositions sweetened therewith
US20070116823A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener for hydration and sweetened hydration composition
US8993027B2 (en) 2005-11-23 2015-03-31 The Coca-Cola Company Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US20070134391A1 (en) 2005-11-23 2007-06-14 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith
US8524304B2 (en) 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US20070116825A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Confection with High-Potency Sweetener
US8962058B2 (en) 2005-11-23 2015-02-24 The Coca-Cola Company High-potency sweetener composition with antioxidant and compositions sweetened therewith
US8791253B2 (en) * 2006-06-19 2014-07-29 The Coca-Cola Company Rebaudioside A composition and method for purifying rebaudioside A
CN101472487B (zh) * 2006-06-19 2013-05-01 可口可乐公司 甜菊双糖苷a组合物及其纯化方法
US9012626B2 (en) 2006-06-19 2015-04-21 The Coca-Cola Company Rebaudioside a composition and method for purifying rebaudioside a
EP2124633B1 (en) * 2007-01-22 2012-03-07 Cargill, Incorporated Method of producing purified rebaudioside a compositions using solvent/antisolvent crystallization

Also Published As

Publication number Publication date
CA2784810A1 (en) 2011-07-07
BR112012016387A2 (pt) 2015-09-01
JP2013516423A (ja) 2013-05-13
PH12012501318A1 (en) 2017-04-26
CN102770436A (zh) 2012-11-07
US20100137569A1 (en) 2010-06-03
MX2012007644A (es) 2012-08-01
EP2519534B1 (en) 2018-05-09
ZA201204841B (en) 2018-11-28
MX345164B (es) 2017-01-19
KR20120116460A (ko) 2012-10-22
EP2519534A1 (en) 2012-11-07
AU2010339459B2 (en) 2016-02-25
DK2519534T3 (en) 2018-08-13
CA2784810C (en) 2018-05-01
IN2012DN05893A (es) 2015-09-18
AU2010339459A1 (en) 2012-08-23
US9012626B2 (en) 2015-04-21
CN106167509A (zh) 2016-11-30
RU2591852C2 (ru) 2016-07-20
RU2012131911A (ru) 2014-02-10
WO2011082288A1 (en) 2011-07-07

Similar Documents

Publication Publication Date Title
CL2012001749A1 (es) Metodos para purificar una composicion de rebaudiosido a, que comprende combinar una composicion de baja pureza con un solvente organico que opcionalmente contiene agua, cristalizar la solucion en un solo paso asi obtener una mezcla de glicosidos de esteviol de pureza mayor al 95%, que contiene rebausiosido a en cantidad mayor al 85%.
AR078647A1 (es) Metodo de purificacion de rebaudiosido d a partir del extracto de estevia y productos que lo contienen como endulzante.
UA116809C2 (uk) Застосування агрохімічних сумішей для збільшення життєздатності рослини
AR081475A1 (es) Tamiz molecular de levyne que contiene cobre para la reduccion selectiva de nox
BRPI0702269A (pt) alcanolamidas e uso do mesmo como aditivos de combustìvel
CL2007001753A1 (es) Metodo para purificar rebaudiosida a sin refinar, mediante la combinacion con un solvente organico acuoso y posterior cristalizacion; y composicion farmaceutica que comprende los polimorfos.
MX349554B (es) Metodo para incrementar la actividad microbiana del suelo.
AR083480A1 (es) Mezclas de stevia que contienen rebaudiosida b
CL2008002076A1 (es) Compuestos derivados de ariloxazoles sustituidos; procedimiento de preparacion de dichos compuestos; composicion farmaceutica que los comprende; y su uso para tratar diabetes, sindrome metabolico, dislipidemias, entre otras enfermedades.
UA111362C2 (uk) Кодування масиву зразків з малою затримкою
CO6400206A2 (es) Composición espumante para alta temperatura y salinidad
CL2007002971A1 (es) Compuestos derivados de aminometil-4-imidazol; procedimiento de preparacion; composicion farmaceutica que los contiene; y su uso para tratar depresion, ansiedad, trastorno bipolar, entre otras.
CL2010001530A1 (es) Compuestos derivados de tiadiazoliloxifenilamidinas; su procedimiento de preparacion; agentes para combatir microorganismos indeseados que comprende a dichos compuestos; uso; procedimiento para combatir microorganismos indeseados; y compuestos intermediarios.
MX2019006290A (es) Composiciones edulcorantes naturales de alta solubilidad.
MX2012002089A (es) Composiciones alcoholicas que tienen un riesgo reducido de acetaldehidemia.
ECSP12012031A (es) Composición farmacéutica que comprende oligopéptidos
CL2012000508A1 (es) Composicion para la aplicacion en cultivos agricolas al aire libre o invernaderos que comprende zeolita, y aditivos; uso de la composicion para aumentar el rendimiento de los cultivos agricolas.
CU20060153A7 (es) Nueva forma cristalina v de agomelatina, procedimiento para su preparación y composiciones farmacéuticas que las contienen
GT201000047A (es) Mejoras en compuestos organicos o relacionadas con los mismos
UY32704A (es) Compuestos de 2,3-dihidro-1h-indeno
CL2007002970A1 (es) Compuestos derivados de aminometil-4-imidazol; procedimiento de preparacion; composicion farmaceutica que los contiene; y su uso para tratar depresion, ansiedad, trastorno bipolar, entre otras.
AR075538A1 (es) Elemento de filtro de membrana con multiples tipos de fibras
GT200600221A (es) Tigeciclina y metodos de preparacion
AR116001A2 (es) Composición farmacéutica 271
HN2012000217A (es) Compuestos derivados de amido espirociclicos y sales farmaceuticamente aceptable de los mismos.