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CL2008000020A1 - Compuestos derivados de 2,4-dianilinopirimidinas sustituidas, inhibidores de proteinas cinasas; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades inflamatorias, diabetes y tumores malignos. - Google Patents

Compuestos derivados de 2,4-dianilinopirimidinas sustituidas, inhibidores de proteinas cinasas; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades inflamatorias, diabetes y tumores malignos.

Info

Publication number
CL2008000020A1
CL2008000020A1 CL2008000020A CL2008000020A CL2008000020A1 CL 2008000020 A1 CL2008000020 A1 CL 2008000020A1 CL 2008000020 A CL2008000020 A CL 2008000020A CL 2008000020 A CL2008000020 A CL 2008000020A CL 2008000020 A1 CL2008000020 A1 CL 2008000020A1
Authority
CL
Chile
Prior art keywords
dianilinopyrimidines
diabetes
prevention
substituted
treatment
Prior art date
Application number
CL2008000020A
Other languages
English (en)
Inventor
Pierre Casellas
Serge Mignani
Monsif Bouaboula
Jean-Flaubert Nguefack
Didier Babin
Maria Mendez-Perez
Jacob-Alsboe Olsen
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of CL2008000020A1 publication Critical patent/CL2008000020A1/es

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Abstract

Compuestos derivados de 2,4-dianilinopirimidinas sustituidas, inhibidores de proteínas cinasas; procedimiento de preparación; composición farmacéutica; y uso para el tratamiento o prevención de enfermedades inflamatorias, diabetes y tumores malignos.
CL2008000020A 2007-01-05 2008-01-03 Compuestos derivados de 2,4-dianilinopirimidinas sustituidas, inhibidores de proteinas cinasas; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades inflamatorias, diabetes y tumores malignos. CL2008000020A1 (es)

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FR0700064A FR2911138B1 (fr) 2007-01-05 2007-01-05 Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk

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CL2008000020A1 true CL2008000020A1 (es) 2009-01-23

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CA (1) CA2672959A1 (es)
CL (1) CL2008000020A1 (es)
FR (1) FR2911138B1 (es)
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US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011144742A1 (en) 2010-05-21 2011-11-24 Chemilia Ab Novel pyrimidine derivatives
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
AU2012230229A1 (en) 2011-03-24 2013-10-10 Noviga Research Ab Novel pyrimidine derivatives
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CN103204827B (zh) * 2012-01-17 2014-12-03 上海科州药物研发有限公司 作为蛋白激酶抑制剂的苯并噻二唑化合物及其制备方法和用途
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AU2014249168B2 (en) 2013-03-12 2018-07-12 Celltaxis, Llc Methods of inhibiting leukotriene A4 hydrolase
AU2014240042C1 (en) 2013-03-14 2019-09-05 Celltaxis, Llc Inhibitors of leukotriene A4 hydrolase
KR20150127246A (ko) 2013-03-14 2015-11-16 켈탁시스, 인코퍼레이티드 류코트라이엔 a4 가수분해효소의 저해제
MX2015011676A (es) 2013-03-14 2016-04-25 Celtaxsys Inc Inhibidores de leucotrieno a4 hidrolasa.
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
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JP6946412B2 (ja) 2016-07-18 2021-10-06 ヤンセン ファーマシューティカ エヌ．ベー． タウｐｅｔ画像化リガンド
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KR20200144579A (ko) 2018-05-14 2020-12-29 어리어드 파마슈티칼스, 인코포레이티드 피리미딘 유도체의 약학 염 및 장애의 치료 방법
JP7386815B2 (ja) 2018-05-31 2023-11-27 セルタクシー、エルエルシー 呼吸器疾患患者の肺増悪を軽減する方法
EP3890715A4 (en) * 2018-12-04 2023-03-29 The Board Of Regents Of The University Of Texas System ANTI-ADENOMATOUS POLYPOSIS COLI (APC) THERAPEUTICS FOR THE TREATMENT OF CANCER
CR20220316A (es) 2019-12-06 2022-10-07 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio
HRP20251504T1 (hr) 2021-06-04 2026-01-02 Vertex Pharmaceuticals Incorporated N-(hidroksialkil (hetero)aril) tetrahidrofuran karboksamidi kao modulatori natrijevih kanala
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FR2911137B1 (fr) * 2007-01-05 2009-02-20 Sanofi Aventis Sa Nouveaux derives de 2,4-dianilinopyrimides, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk

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CN101605783A (zh) 2009-12-16
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FR2911138B1 (fr) 2009-02-20
CA2672959A1 (fr) 2008-08-21
US20100093668A1 (en) 2010-04-15
TW200900068A (en) 2009-01-01
FR2911138A1 (fr) 2008-07-11
WO2008099073A1 (fr) 2008-08-21
AR064730A1 (es) 2009-04-22
UY30857A1 (es) 2008-09-02

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