CH638977A5 - Medikament, enthaltend o-aminobenzoesaeurederivate. - Google Patents

Medikament, enthaltend o-aminobenzoesaeurederivate. Download PDF

Info

Publication number: CH638977A5
Authority: CH; Switzerland
Prior art keywords: activity; compounds; compound; sodium; aminobenzoate
Prior art date: 1978-04-06

Application number

CH318179A

Other languages

German (de)

English (en)

Inventor

Chikao Yoshikumi

Yoshio Ohmura

Fumio Hirose

Masanori Ikuzawa

Kenichi Matsunaga

Takayoshi Fujii

Minoru Ohhara

Takao Ando

Original Assignee

Kureha Chemical Ind Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-04-06

Filing date

1979-04-05

Publication date

1983-10-31

1978-04-06 Priority claimed from JP4059478A external-priority patent/JPS54132239A/ja

1978-04-10 Priority claimed from JP4201478A external-priority patent/JPS54135231A/ja

1978-04-10 Priority claimed from JP4201578A external-priority patent/JPS54135232A/ja

1978-04-11 Priority claimed from JP4257678A external-priority patent/JPS54135738A/ja

1978-05-26 Priority claimed from JP6314678A external-priority patent/JPS54154729A/ja

1978-12-29 Priority claimed from JP16138578A external-priority patent/JPS5924966B2/ja

1978-12-29 Priority claimed from JP53161386A external-priority patent/JPS5924965B2/ja

1979-04-05 Application filed by Kureha Chemical Ind Co Ltd filed Critical Kureha Chemical Ind Co Ltd

1983-10-31 Publication of CH638977A5 publication Critical patent/CH638977A5/de

Links

150000001875 compounds Chemical class 0.000 claims description 85
RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical compound NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 claims description 42
239000003814 drug Substances 0.000 claims description 23
239000011734 sodium Substances 0.000 claims description 16
229910052708 sodium Inorganic materials 0.000 claims description 15
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 13
SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 8
SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical group O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims description 7
SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Chemical group CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 claims description 6
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WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical group OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims description 4
PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Chemical group CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 claims description 4
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WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical group OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 3
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235000013372 meat Nutrition 0.000 description 1
230000008018 melting Effects 0.000 description 1
229940102398 methyl anthranilate Drugs 0.000 description 1
150000002772 monosaccharides Chemical class 0.000 description 1
230000036438 mutation frequency Effects 0.000 description 1
239000013642 negative control Substances 0.000 description 1
239000002736 nonionic surfactant Substances 0.000 description 1
230000037040 pain threshold Effects 0.000 description 1
238000007911 parenteral administration Methods 0.000 description 1
239000002304 perfume Substances 0.000 description 1
230000000144 pharmacologic effect Effects 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
229940088417 precipitated calcium carbonate Drugs 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
150000008265 rhamnosides Chemical class 0.000 description 1
239000008159 sesame oil Substances 0.000 description 1
235000011803 sesame oil Nutrition 0.000 description 1
235000021055 solid food Nutrition 0.000 description 1
239000002904 solvent Substances 0.000 description 1
238000000638 solvent extraction Methods 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
229960001052 streptozocin Drugs 0.000 description 1
238000010254 subcutaneous injection Methods 0.000 description 1
238000006467 substitution reaction Methods 0.000 description 1
239000000829 suppository Substances 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
230000002459 sustained effect Effects 0.000 description 1
230000008961 swelling Effects 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000000080 wetting agent Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CH318179A 1978-04-06 1979-04-05 Medikament, enthaltend o-aminobenzoesaeurederivate. CH638977A5 (de)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
JP4059478A JPS54132239A (en)	1978-04-06	1978-04-06	Anti-tumor agent
JP4201478A JPS54135231A (en)	1978-04-10	1978-04-10	Cardio-vasocular medicine
JP4201578A JPS54135232A (en)	1978-04-10	1978-04-10	Blood sugar depressing agent
JP4257678A JPS54135738A (en)	1978-04-11	1978-04-11	Novel aminobenzoic acid-n-d-mannoside and drugs comprising it
JP6314678A JPS54154729A (en)	1978-05-26	1978-05-26	Aminobenzoic acid derivative and drug preparation containing the same
JP16138578A JPS5924966B2 (ja)	1978-12-29	1978-12-29	アミノ安息香酸誘導体又はその医薬上許容される塩を有効成分とする抗炎症剤
JP53161386A JPS5924965B2 (ja)	1978-12-29	1978-12-29	アミノ安息香酸誘導体又はその医薬上許容し得る塩を有効成分とする解熱鎮痛剤

Publications (1)

Publication Number	Publication Date
CH638977A5 true CH638977A5 (de)	1983-10-31

Family

ID=27564518

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH318179A CH638977A5 (de)	1978-04-06	1979-04-05	Medikament, enthaltend o-aminobenzoesaeurederivate.

Country Status (8)

Country	Link
AU (1)	AU525638B2 (it)
CH (1)	CH638977A5 (it)
DE (1)	DE2914005C2 (it)
FR (1)	FR2421616A1 (it)
GB (1)	GB2018135B (it)
IT (1)	IT1115155B (it)
PH (7)	PH15664A (it)
SE (1)	SE448602B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5716898A (en) *	1980-07-03	1982-01-28	Kureha Chem Ind Co Ltd	Prostaglandin controller containing aminobenzoic derivative
JPS6041079B2 (ja) *	1979-12-14	1985-09-13	呉羽化学工業株式会社	オルト又はメタアミノ安息香酸誘導体
JPS608000B2 (ja)	1980-04-11	1985-02-28	呉羽化学工業株式会社	アミノフエニル誘導体及び該誘導体を含有する生理活性剤
AU554396B2 (en) *	1982-12-03	1986-08-21	Kureha Kagaku Kogyo K.K.	Pharmaceutical compositions of amino benzoic acid derivatives
JPS62289594A (ja) *	1986-06-09	1987-12-16	Kureha Chem Ind Co Ltd	アミノ安息香酸誘導体よりなるソルビト−ル蓄積阻害剤
JPH0627071B2 (ja) *	1988-08-05	1994-04-13	呉羽化学工業株式会社	アミノ安息香酸誘導体を有効成分とする免疫抑制剤の副作用軽減剤
EP0604641B1 (en) *	1992-06-30	2002-03-20	SHAPIRO, Howard, K.	Use of a combination containing an amine or amine-related derivative of benzoic acid and an amino-polysaccharide in the manufacture of a medicament for the treatment of inflammatory diseases
DE4436127A1 (de) *	1994-09-27	1996-03-28	Deutsches Rheumaforschungszent	Verwendung von aromatischen Amiden und Säuren zur Behandlung von rheumatischen Erkrankungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL62054C (it) *	1943-09-30
DE2627076A1 (de) *	1976-06-16	1977-12-29	Max Planck Gesellschaft	Mittel zur inhibierung des zellwachstums

1979
- 1979-03-30 SE SE7902854A patent/SE448602B/sv not_active IP Right Cessation
- 1979-04-03 AU AU45719/79A patent/AU525638B2/en not_active Ceased
- 1979-04-05 CH CH318179A patent/CH638977A5/de not_active IP Right Cessation
- 1979-04-05 GB GB7912020A patent/GB2018135B/en not_active Expired
- 1979-04-06 DE DE2914005A patent/DE2914005C2/de not_active Expired
- 1979-04-06 FR FR7908739A patent/FR2421616A1/fr active Granted
- 1979-04-06 IT IT21652/79A patent/IT1115155B/it active
- 1979-04-06 PH PH22378A patent/PH15664A/en unknown
1980
- 1980-08-04 PH PH24393A patent/PH15606A/en unknown
- 1980-08-04 PH PH24389A patent/PH15174A/en unknown
- 1980-08-04 PH PH24392A patent/PH15576A/en unknown
- 1980-08-04 PH PH24390A patent/PH15636A/en unknown
- 1980-08-04 PH PH24391A patent/PH15190A/en unknown
- 1980-08-04 PH PH24394A patent/PH15640A/en unknown

Also Published As

Publication number	Publication date
DE2914005A1 (de)	1979-10-18
PH15636A (en)	1983-03-11
PH15640A (en)	1983-03-11
AU4571979A (en)	1979-10-11
FR2421616A1 (fr)	1979-11-02
SE446429B (sv)	1986-09-15
GB2018135B (en)	1982-06-16
GB2018135A (en)	1979-10-17
PH15606A (en)	1983-02-28
PH15576A (en)	1983-02-17
IT7921652A0 (it)	1979-04-06
IT1115155B (it)	1986-02-03
FR2421616B1 (it)	1981-02-13
PH15664A (en)	1983-03-11
SE7902854L (sv)	1979-10-07
SE448602B (sv)	1987-03-09
DE2914005C2 (de)	1985-03-21
PH15174A (en)	1982-08-31
AU525638B2 (en)	1982-11-18
PH15190A (en)	1982-09-10

Publication	Publication Date	Title
CH638976A5 (de)	1983-10-31	Medikament, enthaltend p-aminobenzoesaeurederivate.
DE2936078C2 (de)	1982-03-11	Synthetisches Magnesiumaluminiumsilikat und dieses enthaltendes pharmazeutisches Präparat
CH640411A5 (de)	1984-01-13	Medikament zur behandlung von hyperglykaemie, hyperlipaemie, hypertension, entzuendungen, schmerz, fieber oder tumoren.
CH638977A5 (de)	1983-10-31	Medikament, enthaltend o-aminobenzoesaeurederivate.
DE3688807T2 (de)	1994-02-10	Isolierung von Castanospermin und dessen Verwendung als antidiabetisches Heilmittel.
CH641678A5 (de)	1984-03-15	Entzuendungshemmendes und zur behandlung der benignen prostatahypertrophie geeignetes arzneimittel.
CH644018A5 (de)	1984-07-13	Pharmazeutisches mittel zur prostaglandinregulierung.
DE3038327C2 (de)	1985-04-25	N-Glycoside von p-Aminobenzoesäure und diese Verbindungen enthaltende Arzneimittel
DE2318784A1 (de)	1973-10-25	N-(2,4-dihydroxybenzoyl)-4-aminosalizylsaeure
DE3348149C2 (en)	1989-06-01	Use of aminobenzoic acid derivatives for the treatment of kidney disorders
DE3038304A1 (de)	1981-04-23	Aminobenzoesaeureester, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung
DE3107594A1 (de)	1982-02-11	Neue piperazin-verbindungen, verfahren zu ihrer herstellung und ihre verwendung
DE3046796A1 (de)	1981-09-24	"aminobenzoesaeurederivate und deren verwendung"
DE2659465C2 (de)	1983-11-24	Pflanzliche Wirkstoffextrakte aus Hypoxidaceen und ihre Anwendung
DE2952385A1 (de)	1980-07-10	Verfahren zur herstellung von 7-chlor- 2-methyl-3,3a-dihydro-2h,9h-isoxazol (3,2-b) (1,3)-benzoxazin-9-on
DE3105121C2 (de)	1987-01-02	1-(Phenyl)-4-diäthylcarbamoylpiperazin-Verbindungen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2827932A1 (de)	1979-01-18	Biphenylsulfonyliminoverbindungen
DD147544A5 (de)	1981-04-08	Verfahren zur herstellung von rutin-poly(h)-sulfaten
DE3048279A1 (de)	1981-09-10	Aminobenzoesaeurederivate und deren verwendung
EP0056970A1 (de)	1982-08-04	Basisch substituierte Anthranilsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
DD202556A5 (de)	1983-09-21	Verfahren zur herstellung von abkoemmlingen von 2-amino-5-(o-sulphamidophenyl)-1,3,4-thiadiazol
DE1695566C3 (de)	1975-07-03	N hoch 1 -eckige Klammer auf p-AminobenzoteuHonyl eckige Klammer zu -N hoch 3 -eckige Klammer auf 4,5dimethyloxazolyl-(2) eckige Klammer zu -guanidin
AT319934B (de)	1975-01-10	Vzh der neuen 5-n-pyrrylsalicylsaeure und ihrer salze
DE2400531B2 (de)	1976-11-04	2-(4-isobutylphenyl)-propiohydroxamsaeure, deren herstellung und diese enthaltende arzneimittel
DE2411197A1 (de)	1974-09-12	Imidazolderivat

Legal Events

Date	Code	Title	Description
1992-12-31	PL	Patent ceased
2024-10-31	PL	Patent ceased