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CH534124A - Tricyclic amines - anti-depressants sedatives - Google Patents

Tricyclic amines - anti-depressants sedatives

Info

Publication number
CH534124A
CH534124A CH888069A CH888069A CH534124A CH 534124 A CH534124 A CH 534124A CH 888069 A CH888069 A CH 888069A CH 888069 A CH888069 A CH 888069A CH 534124 A CH534124 A CH 534124A
Authority
CH
Switzerland
Prior art keywords
sedatives
depressants
tricyclic amines
opt
chlorine
Prior art date
Application number
CH888069A
Other languages
German (de)
Inventor
Emilio Dr Kyburz
Hans Dr Spiegelberg
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1614466A external-priority patent/CH484044A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH888069A priority Critical patent/CH534124A/en
Priority claimed from CH887369A external-priority patent/CH485649A/en
Publication of CH534124A publication Critical patent/CH534124A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Method for the preparation of tricyclic amines of the general formula (I) and salts thereof with pharmaceutically acceptable acids. where R1 = hydrogen or methyl, R = chlorine or fluorine, R2 and R3 hydrogen, chlorine or fluorine, X = ethylene or vinylene group, the latter opt. substd. by a halogen atom. The exocyclic double bond of the centre ring may be opt. hydrogenated. The compounds are antidepressants, narcotic potentiators, adrenolytic, sedative, antihistamine and local anaesthetic active.
CH888069A 1966-11-08 1967-09-19 Tricyclic amines - anti-depressants sedatives CH534124A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH888069A CH534124A (en) 1966-11-08 1967-09-19 Tricyclic amines - anti-depressants sedatives

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1614466A CH484044A (en) 1966-11-08 1966-11-08 Process for the preparation of tricyclic amines
CH888069A CH534124A (en) 1966-11-08 1967-09-19 Tricyclic amines - anti-depressants sedatives
CH887369A CH485649A (en) 1966-11-08 1969-11-08 Process for the preparation of tricyclic amines

Publications (1)

Publication Number Publication Date
CH534124A true CH534124A (en) 1973-02-28

Family

ID=25703880

Family Applications (1)

Application Number Title Priority Date Filing Date
CH888069A CH534124A (en) 1966-11-08 1967-09-19 Tricyclic amines - anti-depressants sedatives

Country Status (1)

Country Link
CH (1) CH534124A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6545057B2 (en) 2000-09-26 2003-04-08 The Brigham And Women's Hospital Inc. Tricyclic antidepressants and their analogues as long-acting local anesthetics and analgesics
US7074961B2 (en) 2000-09-26 2006-07-11 The Brigham And Women's Hospital, Inc. Antidepressants and their analogues as long-acting local anesthetics and analgesics

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6545057B2 (en) 2000-09-26 2003-04-08 The Brigham And Women's Hospital Inc. Tricyclic antidepressants and their analogues as long-acting local anesthetics and analgesics
US7074961B2 (en) 2000-09-26 2006-07-11 The Brigham And Women's Hospital, Inc. Antidepressants and their analogues as long-acting local anesthetics and analgesics

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Legal Events

Date Code Title Description
PL Patent ceased