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CH498122A - Process for the preparation of a new tetrahydroazepine derivative - Google Patents

Process for the preparation of a new tetrahydroazepine derivative

Info

Publication number
CH498122A
CH498122A CH197668A CH197668A CH498122A CH 498122 A CH498122 A CH 498122A CH 197668 A CH197668 A CH 197668A CH 197668 A CH197668 A CH 197668A CH 498122 A CH498122 A CH 498122A
Authority
CH
Switzerland
Prior art keywords
preparation
new
tetrahydroazepine derivative
tetrahydroazepine
derivative
Prior art date
Application number
CH197668A
Other languages
German (de)
Inventor
Karl Dr Hoegerle
Ernst Dr Habicht
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Priority to CH197668A priority Critical patent/CH498122A/en
Priority to IL30458A priority patent/IL30458A/en
Priority to DK383268AA priority patent/DK123526B/en
Priority to NL6811311A priority patent/NL6811311A/xx
Priority to ES357247A priority patent/ES357247A1/en
Priority to GB38772/68A priority patent/GB1225053A/en
Priority to FR1598948D priority patent/FR1598948A/fr
Priority to DE19681795132 priority patent/DE1795132A1/en
Priority to FR163036A priority patent/FR7915M/fr
Priority to AT797568A priority patent/AT277257B/en
Priority to BE719631D priority patent/BE719631A/xx
Publication of CH498122A publication Critical patent/CH498122A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH197668A 1967-02-17 1968-02-09 Process for the preparation of a new tetrahydroazepine derivative CH498122A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (en) 1968-02-09 1968-02-09 Process for the preparation of a new tetrahydroazepine derivative
IL30458A IL30458A (en) 1968-02-09 1968-07-29 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it
DK383268AA DK123526B (en) 1968-02-09 1968-08-08 Process for the preparation of 6-chloro-2,3,4,5-tetrahydro-1H-3-benzazepine or acid addition salts thereof.
NL6811311A NL6811311A (en) 1968-02-09 1968-08-08
ES357247A ES357247A1 (en) 1968-02-09 1968-08-14 New tetrahydroazepine derivative, process for its production and compositions containing same
GB38772/68A GB1225053A (en) 1968-02-09 1968-08-14 New tetrahydroazepine derivative, process for its production and compositions containing same
FR1598948D FR1598948A (en) 1968-02-09 1968-08-14
DE19681795132 DE1795132A1 (en) 1968-02-09 1968-08-14 Process for the preparation of a new tetrahydroazepine derivative
FR163036A FR7915M (en) 1967-02-17 1968-08-14
AT797568A AT277257B (en) 1968-02-09 1968-08-14 Process for the preparation of a new tetrahydroazepine derivative and its acid addition salts
BE719631D BE719631A (en) 1968-02-09 1968-08-16

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (en) 1968-02-09 1968-02-09 Process for the preparation of a new tetrahydroazepine derivative

Publications (1)

Publication Number Publication Date
CH498122A true CH498122A (en) 1970-10-31

Family

ID=4223010

Family Applications (1)

Application Number Title Priority Date Filing Date
CH197668A CH498122A (en) 1967-02-17 1968-02-09 Process for the preparation of a new tetrahydroazepine derivative

Country Status (10)

Country Link
AT (1) AT277257B (en)
BE (1) BE719631A (en)
CH (1) CH498122A (en)
DE (1) DE1795132A1 (en)
DK (1) DK123526B (en)
ES (1) ES357247A1 (en)
FR (1) FR1598948A (en)
GB (1) GB1225053A (en)
IL (1) IL30458A (en)
NL (1) NL6811311A (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2207430C3 (en) * 1972-02-14 1982-05-13 Pennwalt Corp., 19102 Philadelphia, Pa. 1,2,4,5-Tetrahydro-3H-3-benzazepine, a process for their preparation and a pharmaceutical agent containing them
US4160765A (en) * 1976-11-17 1979-07-10 Smithkline Corporation Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4197297A (en) * 1976-11-17 1980-04-08 Smithkline Corporation 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
EP2332921B1 (en) 2003-06-17 2016-03-02 Arena Pharmaceuticals, Inc. 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
JP4782003B2 (en) 2003-06-17 2011-09-28 アリーナ ファーマシューティカルズ， インコーポレイテッド Benzazepine derivatives useful for the treatment of 5HT2C receptor related diseases
TW200510324A (en) * 2003-08-11 2005-03-16 Lilly Co Eli 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist
NZ555981A (en) 2004-12-21 2011-01-28 Arena Pharm Inc Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
EP2111859A1 (en) 2004-12-23 2009-10-28 Arena Pharmaceuticals, Inc. 5HT2C receptor modulator compositions and methods of use
US8168782B2 (en) 2006-04-03 2012-05-01 Arena Pharmaceuticals, Inc. Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates related thereto
JP5404414B2 (en) 2006-12-05 2014-01-29 アリーナ ファーマシューティカルズ， インコーポレイテッド Method for preparing (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and its intermediates
CN102015591B (en) 2008-03-04 2014-01-29 艾尼纳制药公司 Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-choro-i-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
CN102648170A (en) 2009-06-18 2012-08-22 艾尼纳制药公司 Processes for the preparation of 5-HT2C receptor agonists
KR20130112848A (en) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. Processes for the preparation of 5-ht2c receptor agonists
CA2808909A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
US20130315994A1 (en) 2010-09-01 2013-11-28 Zezhi Jesse Shao Modified-release dosage forms of 5-ht2c agonists useful for weight management
JP2013536859A (en) 2010-09-01 2013-09-26 アリーナ ファーマシューティカルズ， インコーポレイテッド Non-hygroscopic salt of 5-HT2C agonist
SG10201506896RA (en) 2010-09-01 2015-10-29 Arena Pharm Inc Administration of lorcaserin to individuals with renal impairment
MY181736A (en) 2012-10-09 2021-01-05 Arena Pharm Inc Method of weight management

Also Published As

Publication number Publication date
IL30458A0 (en) 1968-09-26
DK123526B (en) 1972-07-03
IL30458A (en) 1972-03-28
FR1598948A (en) 1970-07-15
NL6811311A (en) 1969-08-12
AT277257B (en) 1969-12-29
DE1795132A1 (en) 1972-01-05
ES357247A1 (en) 1970-03-01
GB1225053A (en) 1971-03-17
BE719631A (en) 1969-02-17

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Legal Events

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