CH429716A - Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden - Google Patents
Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-SteroidenInfo
- Publication number
- CH429716A CH429716A CH666862A CH666862A CH429716A CH 429716 A CH429716 A CH 429716A CH 666862 A CH666862 A CH 666862A CH 666862 A CH666862 A CH 666862A CH 429716 A CH429716 A CH 429716A
- Authority
- CH
- Switzerland
- Prior art keywords
- acyloxy
- preparation
- hydroxy steroids
- steroids
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1165961 | 1961-06-24 | ||
| DEV21321A DE1173897B (de) | 1961-06-24 | 1961-09-18 | Verfahren zur Herstellung von cyclischen 17ª‡, 21-Orthoameisensaeureestern von ?-3-Ketosteroiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH429716A true CH429716A (de) | 1967-02-15 |
Family
ID=26001548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH666862A CH429716A (de) | 1961-06-24 | 1962-06-01 | Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US3152154A (de) |
| CH (1) | CH429716A (de) |
| DE (1) | DE1195748B (de) |
| GB (2) | GB963829A (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1047518A (en) * | 1963-06-11 | 1966-11-02 | Glaxo Lab Ltd | 17ª-monoesters of 11,17,21-trihydroxy steroid compounds |
| GB1070751A (en) * | 1964-01-28 | 1967-06-01 | Glaxo Lab Ltd | 17-esters of 17-hydroxy-21-desoxy-steroids |
| US3499081A (en) * | 1966-12-21 | 1970-03-03 | Squibb & Sons Inc | 9-chloroprogestational agents |
| US3502700A (en) * | 1967-01-19 | 1970-03-24 | Squibb & Sons Inc | 17-esters of 9alpha,21-dihalo-11beta,17alpha-dihydroxyprogesterones |
| FR2029415A1 (en) * | 1969-01-30 | 1970-10-23 | Ciba Geigy Ag | 2-chloro-6alpha 9alpha-difluoro-16alpha-methylpregna-1 |
| IT1033042B (it) * | 1970-03-14 | 1979-07-10 | Luso Farmaco Inst | Desametazone 17 valerato e processi per la sua preparazione |
| US3694471A (en) * | 1970-06-08 | 1972-09-26 | Warner Lambert Pharmaceutical | 17-valerate ester of 6{60 ,9{60 -difluorohydrocortisone, its compositions and use as an anti-inflammatory agent |
| US3857941A (en) * | 1970-06-22 | 1974-12-31 | Warner Lambert Co | Pharmaceutical compositions and use of prednisolone 17-benzoate |
| US3789121A (en) * | 1971-11-26 | 1974-01-29 | Warner Lambert Co | 17{60 ,21-orthobutyrates of 6{60 , 9{60 -difluoro-hydrocortisone and 6{60 , 9{60 -difluoroprednisolone, compositions containing same and the use thereof as anti-inflammatory agents |
| US4036831A (en) * | 1975-10-28 | 1977-07-19 | Steroid Development Company Establishment | Trimethyl siloxane steroid intermediates |
| NZ185295A (en) * | 1976-10-04 | 1980-04-28 | Schering Ag | 9-chloroprednisolone derivatives and pharmaceutical compositions |
| DE2735110A1 (de) * | 1977-08-04 | 1979-02-15 | Hoechst Ag | Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung |
| JPS6040439B2 (ja) * | 1978-03-29 | 1985-09-11 | 大正製薬株式会社 | ヒドロコルチゾン誘導体 |
| DE3071122D1 (en) * | 1979-11-16 | 1985-10-31 | Sterosynt Ltd | 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates |
| US4318853A (en) * | 1980-01-31 | 1982-03-09 | The Upjohn Company | 9β,11β-Epoxy-5β-corticoids |
| US4353985A (en) * | 1980-07-14 | 1982-10-12 | Schering Aktiengesellschaft | Process for the preparation of 11 β-hydroxy steroids |
| DE3227312A1 (de) * | 1982-07-19 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung |
| DE3401680A1 (de) * | 1984-01-16 | 1985-07-18 | Schering AG, 1000 Berlin und 4709 Bergkamen | 6(alpha),16ss-dimethylkortikoide |
| ITMI20011762A1 (it) * | 2001-08-10 | 2003-02-10 | Cosmo Spa | Esteri di 17alfa,21-diidrossipregnene, loro uso come agenti anti-androgenetici e procedimenti per la loro preparazione |
| ITMI20071616A1 (it) | 2007-08-03 | 2009-02-04 | Cosmo Spa | Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati. |
| EP3006453A1 (de) | 2014-10-08 | 2016-04-13 | Cosmo Technologies Ltd. | 17alpha-Monoester und 17alpha,21-Diester von Cortodoxon zur Verwendung bei der Behandlung von Tumoren |
| EP3108879A1 (de) | 2015-06-25 | 2016-12-28 | Cassiopea S.p.A. | Hochkonzentrierte formulierung |
| CN116490512B (zh) | 2020-10-19 | 2025-09-16 | 工业化学有限公司 | 21-(乙酰氧基)-17-(1-丙酰氧基)-孕甾-4-烯-3,20-二酮的制备方法 |
| IT202100008429A1 (it) | 2021-04-06 | 2022-10-06 | Farmabios Spa | Processo per la preparazione di cortexolone 17α-propionato e sua nuova forma cristallina idrata |
| CN116135871A (zh) * | 2021-11-16 | 2023-05-19 | 石家庄迪斯凯威医药科技有限公司 | 一种具有抗耐药性的抗菌化合物 |
| CN115466301A (zh) * | 2022-08-29 | 2022-12-13 | 扬州奥锐特药业有限公司 | 一种甾体化合物，其晶型a及它们的制备方法和用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2932656A (en) * | 1957-06-19 | 1960-04-12 | Merck & Co Inc | Production of delta1, 4-3, 20-diketopregnadienes from the corresponding semicarbazones |
| US2971886A (en) * | 1957-11-27 | 1961-02-14 | Upjohn Co | 1-dehydro-17-hydroxyprogesterone acylates and therapeutic composition thereof |
| US2864839A (en) * | 1958-07-25 | 1958-12-16 | Olin Mathieson | delta4, 7, 9(11)-pregnatriene-17alpha, 21-diol-3, 20-dione and process therefor |
-
1962
- 1962-06-01 DE DEV22592A patent/DE1195748B/de active Pending
- 1962-06-01 CH CH666862A patent/CH429716A/de unknown
- 1962-06-11 US US201297A patent/US3152154A/en not_active Expired - Lifetime
- 1962-06-13 GB GB22744/62A patent/GB963829A/en not_active Expired
- 1962-06-13 GB GB22743/62A patent/GB996080A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB963829A (en) | 1964-07-15 |
| US3152154A (en) | 1964-10-06 |
| DE1195748B (de) | 1965-07-01 |
| GB996080A (en) | 1965-06-23 |
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