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CH426822A - Process for the preparation of α- (3-indolyl) -lower aliphatic-acids - Google Patents

Process for the preparation of α- (3-indolyl) -lower aliphatic-acids

Info

Publication number
CH426822A
CH426822A CH335362A CH335362A CH426822A CH 426822 A CH426822 A CH 426822A CH 335362 A CH335362 A CH 335362A CH 335362 A CH335362 A CH 335362A CH 426822 A CH426822 A CH 426822A
Authority
CH
Switzerland
Prior art keywords
indolyl
acids
preparation
lower aliphatic
aliphatic
Prior art date
Application number
CH335362A
Other languages
German (de)
Inventor
Shen Tsung-Ying
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27584499&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH426822(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority claimed from US28693563 external-priority patent/US3161654A/en
Priority claimed from US296451A external-priority patent/US3201414A/en
Priority claimed from US314503A external-priority patent/US3242185A/en
Publication of CH426822A publication Critical patent/CH426822A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH335362A 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic-acids CH426822A (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US9743461A 1961-03-22 1961-03-22
US16461562A 1962-01-05 1962-01-05
US28693563 US3161654A (en) 1962-01-05 1963-06-11 alpha-(1-aroyl-3-indolyl) alkanoic acids
US296451A US3201414A (en) 1963-07-22 1963-07-22 New 1-heteroacyl-3-indolyl aliphatic acids
US31047763A 1963-09-20 1963-09-20
US31045463A 1963-09-20 1963-09-20
US314503A US3242185A (en) 1963-10-07 1963-10-07 Lower aliphatic acids, salts and derivatives thereof
US32386363A 1963-11-04 1963-11-04
US321328A US3275644A (en) 1962-01-05 1963-11-04 Certain 1-azolylindol-3-ylaliphatic acids
US321686A US3275645A (en) 1962-01-05 1963-11-06 N-(1-acyl-3-indolyl)-acids
US437338A US3338921A (en) 1962-01-05 1965-01-26 Thenoic and furoic acids
US442152A US3328423A (en) 1962-01-05 1965-03-23 alpha-(3-indolyl)-cyclopropyl lower aliphatic acids
US528020A US3316267A (en) 1962-01-05 1966-02-15 Indolyl acids

Publications (1)

Publication Number Publication Date
CH426822A true CH426822A (en) 1966-12-31

Family

ID=27584499

Family Applications (8)

Application Number Title Priority Date Filing Date
CH1737366A CH449018A (en) 1961-03-22 1962-03-21 Process for the preparation of the t-butyl esters of N-1-unsubstituted α- (3-indolyl) -lower aliphatic acids
CH1736866A CH450420A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic acids
CH1736966A CH445490A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic-acids
CH1737166A CH445492A (en) 1961-03-22 1962-03-21 Process for the preparation of a- (3-indolyl) -lower aliphatic acids acylated in the 1-position
CH1736766A CH450419A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic esters or amides
CH1737066A CH445491A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic-acids
CH1737266A CH445493A (en) 1961-03-22 1962-03-21 Process for the preparation of the anhydride of N-1-unsubstituted α- (3-indolyl) -lower aliphatic-acids
CH335362A CH426822A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic-acids

Family Applications Before (7)

Application Number Title Priority Date Filing Date
CH1737366A CH449018A (en) 1961-03-22 1962-03-21 Process for the preparation of the t-butyl esters of N-1-unsubstituted α- (3-indolyl) -lower aliphatic acids
CH1736866A CH450420A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic acids
CH1736966A CH445490A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic-acids
CH1737166A CH445492A (en) 1961-03-22 1962-03-21 Process for the preparation of a- (3-indolyl) -lower aliphatic acids acylated in the 1-position
CH1736766A CH450419A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic esters or amides
CH1737066A CH445491A (en) 1961-03-22 1962-03-21 Process for the preparation of α- (3-indolyl) -lower aliphatic-acids
CH1737266A CH445493A (en) 1961-03-22 1962-03-21 Process for the preparation of the anhydride of N-1-unsubstituted α- (3-indolyl) -lower aliphatic-acids

Country Status (9)

Country Link
CH (8) CH449018A (en)
CY (1) CY348A (en)
DE (3) DE1620031B1 (en)
DK (5) DK111959B (en)
FI (2) FI41158B (en)
GB (1) GB997638A (en)
MY (1) MY6600092A (en)
NO (2) NO135064C (en)
SE (5) SE315592B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU176215B (en) 1978-01-27 1981-01-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1
US7135495B2 (en) 2000-03-09 2006-11-14 Ono Pharmaceutical Co., Ltd. Indole derivatives
WO2003022814A1 (en) * 2001-09-07 2003-03-20 Ono Pharmaceutical Co., Ltd. Indole derivatives
WO2021209563A1 (en) 2020-04-16 2021-10-21 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
CN113248419A (en) * 2021-06-09 2021-08-13 云南中医药大学 Synthesis method of novel HuR inhibitor 1-benzenesulfonyl-3-phenylindole-4, 5-dione
CN115417804A (en) * 2022-09-16 2022-12-02 天津药明康德新药开发有限公司 A kind of synthetic method of 7-methyl-1H-indole-5-carboxylic acid

Also Published As

Publication number Publication date
CH450419A (en) 1968-01-31
DE1795543B2 (en) 1979-09-20
FI41159B (en) 1969-06-02
MY6600092A (en) 1966-12-31
DE1620031B1 (en) 1971-04-08
DE1795543C3 (en) 1980-06-04
DE1795543A1 (en) 1972-01-13
SE315593B (en) 1969-10-06
CH449018A (en) 1967-12-31
NO122372B (en) 1971-06-21
CH445493A (en) 1967-10-31
DK120637B (en) 1971-06-28
DK111959B (en) 1968-10-28
CY348A (en) 1966-06-03
CH445492A (en) 1967-10-31
DK120340B (en) 1971-05-17
NO135064C (en) 1977-02-02
DK114975B (en) 1969-08-25
DK116737B (en) 1970-02-09
NO135064B (en) 1976-10-25
SE315282B (en) 1969-09-29
SE315592B (en) 1969-10-06
SE315281B (en) 1969-09-29
SE314984B (en) 1969-09-22
FI41158B (en) 1969-06-02
CH445490A (en) 1967-10-31
DE1620030B1 (en) 1970-03-05
GB997638A (en) 1965-07-07
CH450420A (en) 1968-01-31
CH445491A (en) 1967-10-31

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