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CA970377A - Benzonaphthyridine derivatives - Google Patents

Benzonaphthyridine derivatives

Info

Publication number
CA970377A
CA970377A CA112,767A CA112767A CA970377A CA 970377 A CA970377 A CA 970377A CA 112767 A CA112767 A CA 112767A CA 970377 A CA970377 A CA 970377A
Authority
CA
Canada
Prior art keywords
benzonaphthyridine derivatives
benzonaphthyridine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA112,767A
Inventor
Hans Ott
Rudolf Suess
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent Ltd
Original Assignee
Sandoz Patent Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH708970A external-priority patent/CH527822A/en
Priority claimed from CH708670A external-priority patent/CH527196A/en
Application filed by Sandoz Patent Ltd filed Critical Sandoz Patent Ltd
Application granted granted Critical
Publication of CA970377A publication Critical patent/CA970377A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA112,767A 1970-05-13 1971-05-12 Benzonaphthyridine derivatives Expired CA970377A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH708970A CH527822A (en) 1970-05-13 1970-05-13 Cis-1,2,,3,4,4a-10b-hexahydro-2-methyl-6-phenyl benzo - (c) (1,6) naphthyridine derivs
CH708670A CH527196A (en) 1970-05-13 1970-05-13 Process for the preparation of new benzonaphthyridine derivatives

Publications (1)

Publication Number Publication Date
CA970377A true CA970377A (en) 1975-07-01

Family

ID=25700728

Family Applications (1)

Application Number Title Priority Date Filing Date
CA112,767A Expired CA970377A (en) 1970-05-13 1971-05-12 Benzonaphthyridine derivatives

Country Status (14)

Country Link
JP (1) JPS5432799B1 (en)
AT (1) AT326674B (en)
CA (1) CA970377A (en)
CS (2) CS167202B2 (en)
DE (1) DE2123328A1 (en)
DK (1) DK134488B (en)
ES (1) ES391026A1 (en)
FI (1) FI52089C (en)
FR (1) FR2100649B1 (en)
GB (1) GB1361441A (en)
NL (1) NL7106502A (en)
PL (1) PL76913B1 (en)
SE (1) SE387640B (en)
SU (1) SU423296A3 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
NL7314396A (en) * 1972-10-26 1974-05-01
BE880455A (en) * 1979-01-22 1980-06-06 Sandoz Sa PHARMACEUTICAL COMPOSITIONS BASED ON A BENZO (C) (1,6) NAPHTYRIDINE
SI0988302T1 (en) * 1997-06-03 2003-08-31 Altana Pharma Ag Benzonaphthyridines
SK287231B6 (en) 1999-08-21 2010-04-07 Nycomed Gmbh Medicament comprising a PDE inhibitor and a beta2 adrenoreceptor agonist
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
AU2004226353A1 (en) 2003-04-01 2004-10-14 Laboratoires Serono Sa Inhibitors of phosphodiesterases in infertility
JP2007537233A (en) * 2004-05-12 2007-12-20 ファイザー・プロダクツ・インク Piperidine derivatives as NK1 and NK3 antagonists
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
AU2009256157B2 (en) 2008-06-04 2014-12-18 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (en) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA3100941C (en) 2011-03-01 2024-03-05 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
JP6499591B2 (en) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase receptor agonists for use in colon lavage
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
JP2016514671A (en) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase agonists and uses thereof
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
CN114340631A (en) 2019-05-21 2022-04-12 阿德利克斯股份有限公司 Combination for reducing serum phosphate in a patient

Also Published As

Publication number Publication date
CS167202B2 (en) 1976-04-29
CS162753B2 (en) 1975-07-15
JPS5432799B1 (en) 1979-10-16
FI52089C (en) 1977-06-10
SE387640B (en) 1976-09-13
DK134488C (en) 1977-05-16
FR2100649B1 (en) 1974-08-30
NL7106502A (en) 1971-11-16
PL76913B1 (en) 1975-02-28
DE2123328A1 (en) 1971-12-02
AT326674B (en) 1975-12-29
GB1361441A (en) 1974-07-24
ES391026A1 (en) 1974-04-01
SU423296A3 (en) 1974-04-05
ATA412471A (en) 1975-03-15
DK134488B (en) 1976-11-15
FI52089B (en) 1977-02-28
FR2100649A1 (en) 1972-03-24

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