CA3018991C - Composes induisant la degradation de proteines anti-apoptotiques de la famille bcl-2 et utilisation de ces derniers - Google Patents
Composes induisant la degradation de proteines anti-apoptotiques de la famille bcl-2 et utilisation de ces derniersInfo
- Publication number
- CA3018991C CA3018991C CA3018991A CA3018991A CA3018991C CA 3018991 C CA3018991 C CA 3018991C CA 3018991 A CA3018991 A CA 3018991A CA 3018991 A CA3018991 A CA 3018991A CA 3018991 C CA3018991 C CA 3018991C
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- CA
- Canada
- Prior art keywords
- compound
- bcl
- bond
- linker
- following
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
La présente invention concerne des compositions et des méthodes permettant de détruire sélectivement des cellules sénescentes, la composition comprenant un composé de Formule (I) ou un composé de Formule (II). La destruction sélective de cellules sénescentes pourrait retarder le vieillissement et/ou traiter des troubles liés à l'âge.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662325856P | 2016-04-21 | 2016-04-21 | |
| US62/325,856 | 2016-04-21 | ||
| PCT/US2017/028875 WO2017184995A1 (fr) | 2016-04-21 | 2017-04-21 | Composés induisant la dégradation de protéines anti-apoptotiques de la famille bcl-2 et utilisation de ces derniers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3018991A1 CA3018991A1 (fr) | 2017-10-26 |
| CA3018991C true CA3018991C (fr) | 2026-01-27 |
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