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CA2359110A1 - Nouveau traitement - Google Patents

Nouveau traitement Download PDF

Info

Publication number
CA2359110A1
CA2359110A1 CA002359110A CA2359110A CA2359110A1 CA 2359110 A1 CA2359110 A1 CA 2359110A1 CA 002359110 A CA002359110 A CA 002359110A CA 2359110 A CA2359110 A CA 2359110A CA 2359110 A1 CA2359110 A1 CA 2359110A1
Authority
CA
Canada
Prior art keywords
hepatitis
pharmaceutical pack
vaccine
antiviral agent
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002359110A
Other languages
English (en)
Inventor
Ronald James Boon
Pierre G. Vandepapeliere
Gillian Frances Atkinson
Martine Anne Cecile Wettendorff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2359110A1 publication Critical patent/CA2359110A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention a trait à un produit pharmaceutique contenant, comme ingrédients actifs (1), un agent antiviral agissant contre le virus de l'hépatite B et (2), un vaccin convenant à la prophylaxie ou au traitement de l'infection par virus de l'hépatite B. Ces ingrédients actifs sont utilisés simultanément ou à la suite. Les composants préférés sont un analogue de nucléoside en tant qu'agent antiviral ainsi qu'un vaccin contre le virus de l'hépatite B renfermant un antigène de surface du virus de l'hépatite B.
CA002359110A 1999-01-12 1999-12-21 Nouveau traitement Abandoned CA2359110A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9900630.6 1999-01-12
GB9900630 1999-01-12
PCT/EP1999/010295 WO2000041463A2 (fr) 1999-01-12 1999-12-21 Nouveau traitement

Publications (1)

Publication Number Publication Date
CA2359110A1 true CA2359110A1 (fr) 2000-07-20

Family

ID=10845878

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002359110A Abandoned CA2359110A1 (fr) 1999-01-12 1999-12-21 Nouveau traitement

Country Status (19)

Country Link
EP (1) EP1140163A2 (fr)
JP (1) JP2002534438A (fr)
KR (1) KR20010090011A (fr)
CN (1) CN1391482A (fr)
AR (1) AR022250A1 (fr)
AU (1) AU760574B2 (fr)
BR (1) BR9916893A (fr)
CA (1) CA2359110A1 (fr)
CO (1) CO5241355A1 (fr)
CZ (1) CZ20012544A3 (fr)
HK (1) HK1041434A1 (fr)
HU (1) HUP0105070A2 (fr)
IL (1) IL144186A0 (fr)
NO (1) NO20013337L (fr)
NZ (1) NZ512890A (fr)
PL (1) PL349347A1 (fr)
TR (1) TR200102024T2 (fr)
WO (1) WO2000041463A2 (fr)
ZA (1) ZA200105690B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2628744T3 (es) 1998-05-22 2017-08-03 Ottawa Hospital Research Institute Métodos y productos para inducir inmunidad en mucosas
HK1038929B (zh) 1998-07-31 2005-05-06 株式会社国际癌症免疫研究所 基於癌抑制基因wt1的产物的癌抗原
CN1281625C (zh) 2001-03-22 2006-10-25 株式会社癌免疫研究所 经修饰的wt1肽
WO2003028758A1 (fr) * 2001-09-28 2003-04-10 Haruo Sugiyama Nouvelle methode d'induction de lymphocytes t specifiques d'un antigene
EP1447091A4 (fr) 2001-09-28 2008-02-13 Institute Of Can International Nouvelle methode pour induire des lymphocytes t specifiques d'antigenes
MY131488A (en) * 2002-04-08 2007-08-30 Bristol Myers Squibb Co Low dose liquid entecavir formulations and use
CN101948835A (zh) 2002-10-29 2011-01-19 科勒制药集团股份有限公司 Cpg寡核苷酸在治疗丙型肝炎病毒感染中的应用
WO2004053104A2 (fr) 2002-12-11 2004-06-24 Coley Pharmaceutical Group, Inc. Acides nucleiques 5'cpg et leurs methodes d'utilisation
CN100443117C (zh) * 2003-05-13 2008-12-17 深圳康泰生物制品股份有限公司 一种治疗性乙型肝炎的疫苗制剂、其制备方法及其用途
US8541167B2 (en) 2004-06-03 2013-09-24 Saint Louis University Methods and compositions for vaccination
WO2008104133A1 (fr) * 2007-02-28 2008-09-04 Centro De Ingeniería Genética Y Biotecnología Thérapie combinée pour le traitement de l'hépatite b chronique
WO2020134682A1 (fr) * 2018-12-24 2020-07-02 南京远大赛威信生物医药有限公司 Préparation pharmaceutique pour le traitement de l'hépatite b, procédé de préparation s'y rapportant et utilisation associée
US20240207395A1 (en) * 2021-04-07 2024-06-27 Denka Company Limited Adjuvant activity enhancer and adjuvant composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0414374B1 (fr) * 1989-07-25 1997-10-08 Smithkline Biologicals S.A. Antigènes ainsi que les méthodes pour leur préparation
CN1299288A (zh) * 1998-03-09 2001-06-13 史密丝克莱恩比彻姆生物有限公司 联合疫苗组合物

Also Published As

Publication number Publication date
HUP0105070A2 (hu) 2002-04-29
ZA200105690B (en) 2002-09-25
JP2002534438A (ja) 2002-10-15
PL349347A1 (en) 2002-07-15
NO20013337L (no) 2001-08-17
AU2100900A (en) 2000-08-01
CZ20012544A3 (cs) 2002-01-16
KR20010090011A (ko) 2001-10-17
TR200102024T2 (tr) 2001-12-21
IL144186A0 (en) 2002-05-23
AR022250A1 (es) 2002-09-04
BR9916893A (pt) 2001-11-20
AU760574B2 (en) 2003-05-15
EP1140163A2 (fr) 2001-10-10
HK1041434A1 (zh) 2002-07-12
WO2000041463A3 (fr) 2000-11-09
NO20013337D0 (no) 2001-07-05
WO2000041463A2 (fr) 2000-07-20
CO5241355A1 (es) 2003-01-31
NZ512890A (en) 2003-09-26
CN1391482A (zh) 2003-01-15

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Legal Events

Date Code Title Description
FZDE Discontinued