CA2340616A1 - Proteines secretees et polynucleotides codant pour ces proteines - Google Patents
Proteines secretees et polynucleotides codant pour ces proteines Download PDFInfo
- Publication number
- CA2340616A1 CA2340616A1 CA002340616A CA2340616A CA2340616A1 CA 2340616 A1 CA2340616 A1 CA 2340616A1 CA 002340616 A CA002340616 A CA 002340616A CA 2340616 A CA2340616 A CA 2340616A CA 2340616 A1 CA2340616 A1 CA 2340616A1
- Authority
- CA
- Canada
- Prior art keywords
- seq
- nucleotide sequence
- nucleotide
- amino acid
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 790
- 102000040430 polynucleotide Human genes 0.000 title claims abstract description 778
- 108091033319 polynucleotide Proteins 0.000 title claims abstract description 778
- 239000002157 polynucleotide Substances 0.000 title claims abstract description 778
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 769
- 239000002773 nucleotide Substances 0.000 claims description 1478
- 125000003729 nucleotide group Chemical group 0.000 claims description 1478
- 150000001413 amino acids Chemical class 0.000 claims description 515
- 239000012634 fragment Substances 0.000 claims description 409
- 239000002299 complementary DNA Substances 0.000 claims description 325
- 108091026890 Coding region Proteins 0.000 claims description 159
- 238000000034 method Methods 0.000 claims description 129
- 230000008569 process Effects 0.000 claims description 127
- 239000000203 mixture Substances 0.000 claims description 42
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 13
- 210000004027 cell Anatomy 0.000 claims description 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 238
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 claims 160
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 description 408
- 235000001014 amino acid Nutrition 0.000 description 167
- 230000004071 biological effect Effects 0.000 description 104
- 108020004414 DNA Proteins 0.000 description 65
- 241000282414 Homo sapiens Species 0.000 description 63
- 239000000523 sample Substances 0.000 description 63
- 108091036407 Polyadenylation Proteins 0.000 description 54
- 108091028043 Nucleic acid sequence Proteins 0.000 description 22
- 239000000047 product Substances 0.000 description 21
- 241000894007 species Species 0.000 description 21
- 238000010367 cloning Methods 0.000 description 4
- 238000009396 hybridization Methods 0.000 description 3
- 238000012411 cloning technique Methods 0.000 description 2
- 238000001400 expression cloning Methods 0.000 description 2
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 102000015696 Interleukins Human genes 0.000 description 1
- 108010063738 Interleukins Proteins 0.000 description 1
- 108010074338 Lymphokines Proteins 0.000 description 1
- 102000008072 Lymphokines Human genes 0.000 description 1
- 108010076504 Protein Sorting Signals Proteins 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229940047124 interferons Drugs 0.000 description 1
- 229940047122 interleukins Drugs 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Abstract
La présente invention concerne de nouveaux polynucléotides ainsi que les protéines codées par ces polynucléotides.
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9763898P | 1998-08-24 | 1998-08-24 | |
| US9765998P | 1998-08-24 | 1998-08-24 | |
| US60/097,638 | 1998-08-24 | ||
| US60/097,659 | 1998-08-24 | ||
| US9961898P | 1998-09-09 | 1998-09-09 | |
| US60/099,618 | 1998-09-09 | ||
| US10209298P | 1998-09-28 | 1998-09-28 | |
| US60/102,092 | 1998-09-28 | ||
| US10997898P | 1998-11-25 | 1998-11-25 | |
| US60/109,978 | 1998-11-25 | ||
| US11364698P | 1998-12-23 | 1998-12-23 | |
| US11364598P | 1998-12-23 | 1998-12-23 | |
| US60/113,646 | 1998-12-23 | ||
| US60/113,645 | 1998-12-23 | ||
| US37924699A | 1999-08-23 | 1999-08-23 | |
| US09/379,246 | 1999-08-23 | ||
| PCT/US1999/019351 WO2000011015A1 (fr) | 1998-08-24 | 1999-08-24 | Proteines secretees et polynucleotides codant pour ces proteines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2340616A1 true CA2340616A1 (fr) | 2000-03-02 |
Family
ID=27574713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002340616A Abandoned CA2340616A1 (fr) | 1998-08-24 | 1999-08-24 | Proteines secretees et polynucleotides codant pour ces proteines |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1107978A1 (fr) |
| JP (1) | JP2002537757A (fr) |
| AU (1) | AU5784799A (fr) |
| CA (1) | CA2340616A1 (fr) |
| WO (1) | WO2000011015A1 (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020137890A1 (en) | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030082541A1 (en) * | 1997-09-17 | 2003-05-01 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20020192659A1 (en) * | 1997-09-17 | 2002-12-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7417126B2 (en) | 1997-10-17 | 2008-08-26 | Genentech, Inc. | PRO246 antibodies |
| CA2350395C (fr) * | 1998-11-06 | 2014-07-08 | Martin E. Schwab | Sequences nucleotidiques et proteiques de gene nogo et procedes reposant sur ces sequences |
| US7816492B2 (en) | 1998-11-20 | 2010-10-19 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors |
| US20030017528A1 (en) | 1998-11-20 | 2003-01-23 | Ruoping Chen | Human orphan G protein-coupled receptors |
| EP1133559B1 (fr) * | 1998-11-20 | 2005-08-10 | Arena Pharmaceuticals, Inc. | Recepteur humain orphelin rup3 couple a une proteine g |
| USRE42190E1 (en) | 1998-11-20 | 2011-03-01 | Arena Pharmaceuticals, Inc. | Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors |
| AU3706600A (en) * | 1999-02-26 | 2000-09-14 | Millennium Pharmaceuticals, Inc. | Secreted proteins and uses thereof |
| PT1632499E (pt) * | 1999-03-08 | 2007-09-11 | Genentech Inc | Dispositivo de detecção de impacto para automóveis. |
| EP1189944A4 (fr) * | 1999-06-21 | 2002-09-11 | Smithkline Beecham Corp | Axor16, r cepteur coupl une prot ine g |
| AU6727900A (en) * | 1999-08-27 | 2001-03-26 | Takeda Chemical Industries Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| EP1225224A4 (fr) * | 1999-10-01 | 2004-03-24 | Kyowa Hakko Kogyo Kk | Adn reagissant a la contrainte de cisaillement |
| AU7999300A (en) * | 1999-10-07 | 2001-05-10 | Zymogenetics Inc. | Novel human phosphodiesterase zcytor13 |
| US6750054B2 (en) | 2000-05-18 | 2004-06-15 | Lexicon Genetics Incorporated | Human semaphorin homologs and polynucleotides encoding the same |
| EP1669371A3 (fr) * | 1999-12-01 | 2006-06-21 | Genentech, Inc. | Composition et procédés de diagnostic de tumeurs |
| US20040053244A1 (en) * | 2000-05-18 | 2004-03-18 | Shyam Ramakrishnan | Regulation of human galanin receptor-like g protein coupled receptor |
| WO2002004518A2 (fr) * | 2000-07-06 | 2002-01-17 | Bayer Corporation | Recepteur humain couple aux proteines g de type neuropeptide y |
| WO2002074237A2 (fr) * | 2001-03-19 | 2002-09-26 | Corixa Corporation | Compositions et procedes de therapie et de diagnostic du cancer du rein |
| JP2003088388A (ja) | 2001-09-14 | 2003-03-25 | Herikkusu Kenkyusho:Kk | 新規な全長ｃＤＮＡ |
| EP1293569A3 (fr) * | 2001-09-14 | 2004-03-31 | Research Association for Biotechnology | Clones d'ADNc complets |
| WO2003037931A2 (fr) * | 2001-11-01 | 2003-05-08 | Amersham Plc | Proteine 1 de type angiomotine humaine |
| US7338772B2 (en) | 2002-04-12 | 2008-03-04 | Schering Corporation | G-protein coupled receptor ligands and methods |
| AU2003261874A1 (en) * | 2002-09-02 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Adrenocortical hormone secretion controller |
| FR2848569A1 (fr) * | 2002-12-17 | 2004-06-18 | Exonhit Therapeutics Sa | Variants de kallikrein-2 et kallikrein-3 humaines et leurs utilisations |
| WO2004106935A2 (fr) * | 2003-05-27 | 2004-12-09 | Bayer Healthcare Ag | Agents diagnostiques et therapeutiques destines a des maladies associees au recepteur 103 couples aux proteines g (gpr103) |
| CA2561947A1 (fr) | 2004-04-09 | 2005-10-20 | Takeda Pharmaceutical Company Limited | Agents de prevention/remedes contre le cancer |
| EP1757691A4 (fr) | 2004-04-14 | 2008-10-08 | Banyu Pharma Co Ltd | Nouveaux gpr103 de singe et qrfp de singe et proced d'evaluation d'un compose en utilisant le gpr103 |
| WO2008118100A1 (fr) * | 2007-03-23 | 2008-10-02 | Agency For Science, Technology And Research | Procédé d'amélioration de la migration de cellules neurales précurseurs |
| WO2015016386A1 (fr) * | 2013-07-30 | 2015-02-05 | Sbi Biotech Co., Ltd. | Médicament comprenant un anticorps anti-phospholipase d4 |
-
1999
- 1999-08-24 WO PCT/US1999/019351 patent/WO2000011015A1/fr not_active Ceased
- 1999-08-24 JP JP2000566287A patent/JP2002537757A/ja active Pending
- 1999-08-24 AU AU57847/99A patent/AU5784799A/en not_active Abandoned
- 1999-08-24 CA CA002340616A patent/CA2340616A1/fr not_active Abandoned
- 1999-08-24 EP EP99945180A patent/EP1107978A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002537757A (ja) | 2002-11-12 |
| AU5784799A (en) | 2000-03-14 |
| EP1107978A1 (fr) | 2001-06-20 |
| WO2000011015A1 (fr) | 2000-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |