CA2230813A1 - Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit - Google Patents
Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuitInfo
- Publication number
- CA2230813A1 CA2230813A1 CA002230813A CA2230813A CA2230813A1 CA 2230813 A1 CA2230813 A1 CA 2230813A1 CA 002230813 A CA002230813 A CA 002230813A CA 2230813 A CA2230813 A CA 2230813A CA 2230813 A1 CA2230813 A1 CA 2230813A1
- Authority
- CA
- Canada
- Prior art keywords
- efficiency
- skin
- patient
- delivery device
- conversion circuit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000006243 chemical reaction Methods 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003792 electrolyte Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Abstract
An iontophoresis system includes a transdermal patch (23) for placement against the skin of a patient and a controller (24, 26) electrically connected to the patch (23). The patch (23) includes an anode and cathode electrode, and holds an electrolyte and a medication.
The controller includes a DC-DC converter circuit (24) which generates output voltage that is provided to the anode electrode. The controller also includes an adjustable current regulator circuit (26). The current regulator circuit (26) is coupled to the cathode electrode and is adjustable to provide a desired current flow through the electrodes and the skin of the patient. The DC-DC converter circuit (24) is responsive to the voltage drop across the electrodes and adjusts its ouptut voltage in response to this voltage drop and changes in the impedance of the patient's skin.
The controller includes a DC-DC converter circuit (24) which generates output voltage that is provided to the anode electrode. The controller also includes an adjustable current regulator circuit (26). The current regulator circuit (26) is coupled to the cathode electrode and is adjustable to provide a desired current flow through the electrodes and the skin of the patient. The DC-DC converter circuit (24) is responsive to the voltage drop across the electrodes and adjusts its ouptut voltage in response to this voltage drop and changes in the impedance of the patient's skin.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/520,521 | 1995-08-29 | ||
| US08/520,521 US6167301A (en) | 1995-08-29 | 1995-08-29 | Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit |
| PCT/US1996/014022 WO1997007854A1 (en) | 1995-08-29 | 1996-08-28 | Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2230813A1 true CA2230813A1 (en) | 1997-03-06 |
| CA2230813C CA2230813C (en) | 2006-10-31 |
Family
ID=37395813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002230813A Expired - Fee Related CA2230813C (en) | 1995-08-29 | 1996-08-28 | Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2230813C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6678555B2 (en) | 1999-05-20 | 2004-01-13 | Vyteris, Inc. | Circuits for increasing the reliability of an iontophoretic system |
-
1996
- 1996-08-28 CA CA002230813A patent/CA2230813C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6678555B2 (en) | 1999-05-20 | 2004-01-13 | Vyteris, Inc. | Circuits for increasing the reliability of an iontophoretic system |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2230813C (en) | 2006-10-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU6962496A (en) | Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit | |
| KR100454667B1 (en) | An electrotransport delivery device with voltage boosting circuit | |
| EP0138347B1 (en) | An iontophoresis device | |
| US5246418A (en) | Iontophresis system having features for reducing skin irritation | |
| CA2121372C (en) | Iontophoretic delivery device and power supply therefor | |
| AU655859B2 (en) | Iontophoresis system having features for reducing skin irritation | |
| EP0847775B1 (en) | Iontophoresis device and method of current control therefor | |
| AU731862B2 (en) | Transdermal or transmucosal drug delivery device | |
| JPH064096B2 (en) | Skin adhesive type low frequency treatment device | |
| US5983133A (en) | Iontophoresis system with voltage step-up circuit | |
| CA2314929C (en) | Regulator with artificial load to maintain regulated delivery | |
| US5256137A (en) | Biphasic power source for use in an iontophoretic drug delivery system | |
| EP0308572B1 (en) | An iontophoresis device | |
| JPH0245461B2 (en) | ||
| WO2009021128A1 (en) | Electrotransport drug delivery device adaptable to skin resistance change | |
| CA2230813A1 (en) | Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit | |
| JP2839279B2 (en) | Device for iontophoresis | |
| RU9740U1 (en) | DEVICE FOR MEDICINAL ELECTROPHORESIS | |
| CN1101579A (en) | DC precardia therapeutic instrument |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |