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CA2230813A1 - Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit - Google Patents

Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit

Info

Publication number
CA2230813A1
CA2230813A1 CA002230813A CA2230813A CA2230813A1 CA 2230813 A1 CA2230813 A1 CA 2230813A1 CA 002230813 A CA002230813 A CA 002230813A CA 2230813 A CA2230813 A CA 2230813A CA 2230813 A1 CA2230813 A1 CA 2230813A1
Authority
CA
Canada
Prior art keywords
efficiency
skin
patient
delivery device
conversion circuit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002230813A
Other languages
French (fr)
Other versions
CA2230813C (en
Inventor
Ronald J. Flower
James M. Devine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vyteris Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/520,521 external-priority patent/US6167301A/en
Application filed by Individual filed Critical Individual
Publication of CA2230813A1 publication Critical patent/CA2230813A1/en
Application granted granted Critical
Publication of CA2230813C publication Critical patent/CA2230813C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)

Abstract

An iontophoresis system includes a transdermal patch (23) for placement against the skin of a patient and a controller (24, 26) electrically connected to the patch (23). The patch (23) includes an anode and cathode electrode, and holds an electrolyte and a medication.
The controller includes a DC-DC converter circuit (24) which generates output voltage that is provided to the anode electrode. The controller also includes an adjustable current regulator circuit (26). The current regulator circuit (26) is coupled to the cathode electrode and is adjustable to provide a desired current flow through the electrodes and the skin of the patient. The DC-DC converter circuit (24) is responsive to the voltage drop across the electrodes and adjusts its ouptut voltage in response to this voltage drop and changes in the impedance of the patient's skin.
CA002230813A 1995-08-29 1996-08-28 Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit Expired - Fee Related CA2230813C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/520,521 1995-08-29
US08/520,521 US6167301A (en) 1995-08-29 1995-08-29 Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
PCT/US1996/014022 WO1997007854A1 (en) 1995-08-29 1996-08-28 Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit

Publications (2)

Publication Number Publication Date
CA2230813A1 true CA2230813A1 (en) 1997-03-06
CA2230813C CA2230813C (en) 2006-10-31

Family

ID=37395813

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002230813A Expired - Fee Related CA2230813C (en) 1995-08-29 1996-08-28 Iontophoretic drug delivery device having high-efficiency dc-to-dc energy conversion circuit

Country Status (1)

Country Link
CA (1) CA2230813C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6678555B2 (en) 1999-05-20 2004-01-13 Vyteris, Inc. Circuits for increasing the reliability of an iontophoretic system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6678555B2 (en) 1999-05-20 2004-01-13 Vyteris, Inc. Circuits for increasing the reliability of an iontophoretic system

Also Published As

Publication number Publication date
CA2230813C (en) 2006-10-31

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed