CA2132873C - Peptides useful for inducing tolerance - Google Patents

Peptides useful for inducing tolerance Download PDF

Info

Publication number: CA2132873C
Authority: CA; Canada
Prior art keywords: peptide; seq; cell; peptides; protein
Prior art date: 1992-03-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

CA2132873A

Other languages

English (en)

French (fr)

Other versions

CA2132873A1 (en

Inventor

Malcolm L. Gefter

Richard D. Garman

Julia L. Greenstein

Mei-Chang Kuo

Thomas J. Briner

Malcolm Morville

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Patent GmbH

Original Assignee

Merck Patent GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-25

Filing date

1993-03-25

Publication date

2012-10-16

1993-03-25 Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH

1993-09-30 Publication of CA2132873A1 publication Critical patent/CA2132873A1/en

2012-10-16 Application granted granted Critical

2012-10-16 Publication of CA2132873C publication Critical patent/CA2132873C/en

2013-03-25 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Urology & Nephrology (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
General Engineering & Computer Science (AREA)
Hematology (AREA)
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Physiology (AREA)
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Tropical Medicine & Parasitology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Food Science & Technology (AREA)
Animal Behavior & Ethology (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Cell Biology (AREA)
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Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
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CA2132873A 1992-03-25 1993-03-25 Peptides useful for inducing tolerance Expired - Lifetime CA2132873C (en)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US85731192A	1992-03-25	1992-03-25
US07/857,311		1992-03-25
US88471892A	1992-05-15	1992-05-15
US07/884,718		1992-05-15
US611693A	1993-01-15	1993-01-15
US08/006,116		1993-01-15
PCT/US1993/002462 WO1993019178A2 (en)	1992-03-25	1993-03-25	Peptides useful for inducing tolerance

Publications (2)

Publication Number	Publication Date
CA2132873A1 CA2132873A1 (en)	1993-09-30
CA2132873C true CA2132873C (en)	2012-10-16

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ID=27358042

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA2132873A Expired - Lifetime CA2132873C (en)	1992-03-25	1993-03-25	Peptides useful for inducing tolerance

Country Status (7)

Country	Link
EP (1)	EP0672134A1 (es)
JP (1)	JPH07505365A (es)
AU (1)	AU677954B2 (es)
CA (1)	CA2132873C (es)
IL (1)	IL105153A (es)
MX (1)	MX9301675A (es)
WO (1)	WO1993019178A2 (es)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6019972A (en)	1989-11-03	2000-02-01	Immulogic Pharmaceutical Corporation	Peptides of human T cell reactive feline protein (TRFP)
US6120769A (en) *	1989-11-03	2000-09-19	Immulogic Pharmaceutical Corporation	Human T cell reactive feline protein (TRFP) isolated from house dust and uses therefor
CA2164326A1 (en) *	1993-06-02	1994-12-08	Wayne Robert Thomas	Cryptic peptides for use in inducing immunologic tolerance
US6759234B1 (en) *	1994-09-02	2004-07-06	Immulogic Pharmaceutical Corporation	Compositions and methods for administering to humans, peptides capable of down regulating an antigen specific immune response
CA2203629A1 (en) *	1994-10-25	1996-05-02	Dawn Smilek	Compositions and treatment for multiple sclerosis
US6379670B1 (en)	1994-11-18	2002-04-30	Neurocrine Biosciences, Inc.	Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6251396B1 (en)	1994-11-18	2001-06-26	Neurocrine Biosciences, Inc.	Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6737406B1 (en)	1996-03-21	2004-05-18	Circassia, Ltd.	Cryptic peptides and method for their identification
DE69737659T2 (de)	1996-06-14	2007-12-27	Meiji Dairies Corp.	Peptide aus t-zellepitopen
US6780416B1 (en)	2000-02-18	2004-08-24	Ecole Polytechnique Federale De Lausanne	Bee venom polypeptides and methods of use thereof
US7923209B2 (en)	2003-03-14	2011-04-12	Anergis, S.A.	Allergen peptide fragments and use thereof
AT503690A1 (de) *	2006-06-09	2007-12-15	Biomay Ag	Hypoallergene moleküle
EP3269379A1 (en)	2008-11-30	2018-01-17	Immusant, Inc.	Compositions and methods for treatment of celiac disease
US10449228B2 (en)	2013-09-10	2019-10-22	Immusant, Inc.	Dosage of a gluten peptide composition
CA2962933A1 (en)	2014-09-29	2016-04-07	Immusant, Inc.	Use of hla genetic status to assess or select treatment of celiac disease

Family Cites Families (3)

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Publication number	Priority date	Publication date	Assignee	Title
JP3251012B2 (ja) *	1989-11-03	2002-01-28	イミユロジク・フアーマシユーチカル・コーポレーシヨン	室内塵から単離したヒトｔ細胞反応性猫蛋白質（ｔｒｆｐ）及びその利用
US5328991A (en) *	1989-11-03	1994-07-12	Immulogic Pharmaceutical Corp.	Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes
NZ244782A (en) *	1991-10-16	1996-12-20	Immulogic Pharma Corp	Isolated peptides having t-cell stimulating activity, pharmaceutical composition

1993
- 1993-03-24 IL IL10515393A patent/IL105153A/en not_active IP Right Cessation
- 1993-03-25 AU AU39226/93A patent/AU677954B2/en not_active Expired
- 1993-03-25 WO PCT/US1993/002462 patent/WO1993019178A2/en not_active Ceased
- 1993-03-25 JP JP5516715A patent/JPH07505365A/ja active Pending
- 1993-03-25 MX MX9301675A patent/MX9301675A/es unknown
- 1993-03-25 EP EP93908385A patent/EP0672134A1/en not_active Withdrawn
- 1993-03-25 CA CA2132873A patent/CA2132873C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU3922693A (en)	1993-10-21
EP0672134A1 (en)	1995-09-20
WO1993019178A3 (en)	1993-11-25
JPH07505365A (ja)	1995-06-15
WO1993019178A2 (en)	1993-09-30
MX9301675A (es)	1993-12-01
IL105153A0 (en)	1993-07-08
IL105153A (en)	1999-12-22
AU677954B2 (en)	1997-05-15
CA2132873A1 (en)	1993-09-30

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