CA2198667C - Cooling sensation composition comprising 3-1-menthoxy propane 1, 2-diol - Google Patents
Cooling sensation composition comprising 3-1-menthoxy propane 1, 2-diol Download PDFInfo
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- CA2198667C CA2198667C CA 2198667 CA2198667A CA2198667C CA 2198667 C CA2198667 C CA 2198667C CA 2198667 CA2198667 CA 2198667 CA 2198667 A CA2198667 A CA 2198667A CA 2198667 C CA2198667 C CA 2198667C
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- diol
- feet
- cooling
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- 230000035597 cooling sensation Effects 0.000 title claims description 20
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
This invention pertains to a topical composition to cool and refresh tired, sore feet and other parts of the body. The composition comprises a moisturizer and the cooling composition 3-1-Menthoxypropane-1,2-diol. This invention also relates to methods for preparing and using a topical composition to cool and refresh tired, sore feet.
Description
COOLING SENSATION COMPOSITION COMPRISING
3-1-MENTHOXY PROPANE I, 2-DIOL
Field of the Invention This invention relates generally to a topical composition to cool and refresh tired, sore feet and other parts of the body. More specifically the invention relates to moisturizers in the form of lotions, creams, and the like formulated with a cooling composition that imparts a cooling sensation when applied to the skin of the feet or other parts of the body.
Back~:;round of the Invention The problem of sore, tired, aching feet is almost universal. One study reports that 85%
of the population has foot problems at one time or another. Some people report their feet feel "hot" or "tired." Others describe "swollen" and "aching" feet. Many men and women are troubled by painful corns. For some, the skin on their feet is often uncomfortably dry. These various problems merge in people's minds when they describe sore feet.
A variety of remedies for treating sore, aching feet are known. These include shoe inserts, orthopedic appliances, foot massages and foot baths. In addition it is known that the use of moisturizers and massage oils can help relieve aching feet. Some people have a regular ritual to relieve their foot problems. This may involve regularly rubbing lotion on the feet, or using a pumice stone or a file to remove hard, callused areas.
Compositions for rubbing on the feet to soothe them are known. These compositions may be as simple as vegetable oils such as sesame oil, or they may be more complex compositions comprising a mixture of lubricants, emulsifiers, humectants, stabilizers, fragrances, and the like.
In some cases one or more ingredients to impart a cooling sensation are added to these compositions. For example, compositions combining moisturizers with large amounts of coolants such as menthol, peppermint oil or eucalyptus oil in amounts sufficient to impart a cooling sensation are known. However, when used in effective amounts these oils often have a strong, undesirable odor.
In addition to the feet, other parts of the body may also feel sore and aching, or hot and tired. The back and shoulders, for example, may sometimes be sore as the result of exercise or other physical activity. The hands, too, can feel hot and sore after certain activities. Compositions used to soothe these other body parts are known and used. Like the compositions used to treat the feet, these compositions containing coolants often have the same strong undesirable odor found in foot therapy compositions.
U. S. Patent No. 4,459,425, assigned to Takasago Perfumery Co., Ltd., discloses the compound 3-I-Menthoxypropane-1,2-diol (hereinafter "MPD"). This patent teaches that when used in toothpowder, chewing gum; and hard, MPD can impart a long-lasting cool, refreshing feeling having no bitter after-taste.
It would be advantageous to provide a topical composition to relieve sore, tired, aching feet and other parts of the body by providing a cooling sensation to the treated part or parts that does not require the use of a large quantity of a coolant with a strong, undesirable odor. It would be further advantageous if the topical composition had a pleasant odor that was appealing to the user of the composition.
SLrMMARY
The present invention is directed to a topical composition that imparts a cooling sensation to the skin of the feet and other parts of the body comprising topical compositions such as liquids, creams, lotions, gels, and the like, and the cooling compound menthoxypropane 1,2-diol (hereinafter "MPD") The present invention is further directed to a topical composition that imparts a cooling sensation to the skin of the feet and other parts of the body hat has a pleasant scent comprising rtopical compositions such as liquids, creams, lotions, gels, and the like; the cooling compound MPD; and fragrances provided by natural plant extracts.
The present invention is further directed to a method of making a topical composition that imparts a cooling sensation to the skin of the feet and other parts of the body comprising topical compositions such as liquids, creams, lotions, gels, and the like and the cooling compound MPD.
The present invention is further directed to a method of using a topical composition by applying it to the skin of the feet and other parts of the body in a sufficient amount to impart a cooling sensation to the skin comprising topical compositions such as liquids, creams, lotions, gels, and the like and the cooling compound MPD.
Detailed Description of the Invention This invention relates to topical compositions that impart a cooling sensation to the skin of the feet and other parts of the body comprising: (a) topical compositions that be applied to the skin in the form of a liquid, cream, lotion, gel, roll-on, powder, spray, aerosol, stick and the like; and, (b) at least one excipient comprising 3-1-menthoxy propane 1,2-diol (hereinafter "MPD") in an amount effective for the composition to provide a cooling sensation to the skin.
This invention further relates to topical compositions that impart a cooling sensation to the skin of the feet and other parts of the body comprising: (a) topical compositions that be applied to the skin in the form of a liquid, cream, lotion, gel, roll-on, powder, spray, aerosol, stick and the like; (b) at least on excipient comprising MPD in an amount effective for the composition to provide a cooling sensation to the skin; and, (c) fragrances provided by natural plant extracts.
One component of the compositions of this invention is MPD. This material is described in detail in U.S. Patent No. 4,459,425, issued July 10, 1984 to Amano et al. and assigned to Takasago Perfumery Co., Ltd. While not to be limited by theory, it is believed that the benefits obtained by the use of MPD in the compositions of this invention are the result of the unique cooling profile of this compound. MPD is commercially available from Takasago Perfumery Co., Ltd., Tokyo, Japan.
The topical compositions of this invention comprise an amount of MPD effective for imparting a cooling sensation to the skin. MPD preferably comprises from about 0.01 % to about 2.0% weight/volume (hereinafter "w/v"); more preferably from about 0.1 %
to about 1.0% w/v; and most preferably from about 0.3% to about 0.6% w/v of the total composition.
Other compositions besides MPD that impart cooling properties may be optionally included in the topical compositions of this invention. These include, but are not limited to, naturally occurring essential oils with cooling properties such as eucalyptus, peppermint oils and menthol.
The topical compositions of this invention include various forms of topical products including, but not limited to, liquids, creams, lotions, gels, roll-ons, sprays, aerosols, sticks, and the like. These compositions are formulated with ingredients known to one skilled in the art. These ingredients include, for example, humectants, oils, occlusive agents, keratin softening agents, emulsifiers, stabilizers and thickeners, and preservatives.
3-1-MENTHOXY PROPANE I, 2-DIOL
Field of the Invention This invention relates generally to a topical composition to cool and refresh tired, sore feet and other parts of the body. More specifically the invention relates to moisturizers in the form of lotions, creams, and the like formulated with a cooling composition that imparts a cooling sensation when applied to the skin of the feet or other parts of the body.
Back~:;round of the Invention The problem of sore, tired, aching feet is almost universal. One study reports that 85%
of the population has foot problems at one time or another. Some people report their feet feel "hot" or "tired." Others describe "swollen" and "aching" feet. Many men and women are troubled by painful corns. For some, the skin on their feet is often uncomfortably dry. These various problems merge in people's minds when they describe sore feet.
A variety of remedies for treating sore, aching feet are known. These include shoe inserts, orthopedic appliances, foot massages and foot baths. In addition it is known that the use of moisturizers and massage oils can help relieve aching feet. Some people have a regular ritual to relieve their foot problems. This may involve regularly rubbing lotion on the feet, or using a pumice stone or a file to remove hard, callused areas.
Compositions for rubbing on the feet to soothe them are known. These compositions may be as simple as vegetable oils such as sesame oil, or they may be more complex compositions comprising a mixture of lubricants, emulsifiers, humectants, stabilizers, fragrances, and the like.
In some cases one or more ingredients to impart a cooling sensation are added to these compositions. For example, compositions combining moisturizers with large amounts of coolants such as menthol, peppermint oil or eucalyptus oil in amounts sufficient to impart a cooling sensation are known. However, when used in effective amounts these oils often have a strong, undesirable odor.
In addition to the feet, other parts of the body may also feel sore and aching, or hot and tired. The back and shoulders, for example, may sometimes be sore as the result of exercise or other physical activity. The hands, too, can feel hot and sore after certain activities. Compositions used to soothe these other body parts are known and used. Like the compositions used to treat the feet, these compositions containing coolants often have the same strong undesirable odor found in foot therapy compositions.
U. S. Patent No. 4,459,425, assigned to Takasago Perfumery Co., Ltd., discloses the compound 3-I-Menthoxypropane-1,2-diol (hereinafter "MPD"). This patent teaches that when used in toothpowder, chewing gum; and hard, MPD can impart a long-lasting cool, refreshing feeling having no bitter after-taste.
It would be advantageous to provide a topical composition to relieve sore, tired, aching feet and other parts of the body by providing a cooling sensation to the treated part or parts that does not require the use of a large quantity of a coolant with a strong, undesirable odor. It would be further advantageous if the topical composition had a pleasant odor that was appealing to the user of the composition.
SLrMMARY
The present invention is directed to a topical composition that imparts a cooling sensation to the skin of the feet and other parts of the body comprising topical compositions such as liquids, creams, lotions, gels, and the like, and the cooling compound menthoxypropane 1,2-diol (hereinafter "MPD") The present invention is further directed to a topical composition that imparts a cooling sensation to the skin of the feet and other parts of the body hat has a pleasant scent comprising rtopical compositions such as liquids, creams, lotions, gels, and the like; the cooling compound MPD; and fragrances provided by natural plant extracts.
The present invention is further directed to a method of making a topical composition that imparts a cooling sensation to the skin of the feet and other parts of the body comprising topical compositions such as liquids, creams, lotions, gels, and the like and the cooling compound MPD.
The present invention is further directed to a method of using a topical composition by applying it to the skin of the feet and other parts of the body in a sufficient amount to impart a cooling sensation to the skin comprising topical compositions such as liquids, creams, lotions, gels, and the like and the cooling compound MPD.
Detailed Description of the Invention This invention relates to topical compositions that impart a cooling sensation to the skin of the feet and other parts of the body comprising: (a) topical compositions that be applied to the skin in the form of a liquid, cream, lotion, gel, roll-on, powder, spray, aerosol, stick and the like; and, (b) at least one excipient comprising 3-1-menthoxy propane 1,2-diol (hereinafter "MPD") in an amount effective for the composition to provide a cooling sensation to the skin.
This invention further relates to topical compositions that impart a cooling sensation to the skin of the feet and other parts of the body comprising: (a) topical compositions that be applied to the skin in the form of a liquid, cream, lotion, gel, roll-on, powder, spray, aerosol, stick and the like; (b) at least on excipient comprising MPD in an amount effective for the composition to provide a cooling sensation to the skin; and, (c) fragrances provided by natural plant extracts.
One component of the compositions of this invention is MPD. This material is described in detail in U.S. Patent No. 4,459,425, issued July 10, 1984 to Amano et al. and assigned to Takasago Perfumery Co., Ltd. While not to be limited by theory, it is believed that the benefits obtained by the use of MPD in the compositions of this invention are the result of the unique cooling profile of this compound. MPD is commercially available from Takasago Perfumery Co., Ltd., Tokyo, Japan.
The topical compositions of this invention comprise an amount of MPD effective for imparting a cooling sensation to the skin. MPD preferably comprises from about 0.01 % to about 2.0% weight/volume (hereinafter "w/v"); more preferably from about 0.1 %
to about 1.0% w/v; and most preferably from about 0.3% to about 0.6% w/v of the total composition.
Other compositions besides MPD that impart cooling properties may be optionally included in the topical compositions of this invention. These include, but are not limited to, naturally occurring essential oils with cooling properties such as eucalyptus, peppermint oils and menthol.
The topical compositions of this invention include various forms of topical products including, but not limited to, liquids, creams, lotions, gels, roll-ons, sprays, aerosols, sticks, and the like. These compositions are formulated with ingredients known to one skilled in the art. These ingredients include, for example, humectants, oils, occlusive agents, keratin softening agents, emulsifiers, stabilizers and thickeners, and preservatives.
The topical compositions of this invention can also include fragrances. These fragrances may be synthetic or they may be derived from natural sources.
Preferably fragrances from natural sources are used in the compositions of this invention. These fragrances include, but are not limited to, peppermint, eucalyptol, rosewood, lavender, grapefruit, patchouli, geranium, and rosemary. The amount of fragrance used is sufficient to impart an acceptable scent to the composition.
Humectants may also be used in the topical compositions of this invention.
Humectants promote retention of water due to their hygroscopicity, thereby easing the feeling of dryness. Suitable humectants include, but are not limited to, propylene glycol; glycerin;
sorbitol; butylene glycol; hexylene glycol; amino acids; and aloe vera.
Occlusive agents may also be used in the topical compositions of this invention.
Occlusive agents are substances that promote retention of water due to their hydrophobicity, thereby preventing water loss from the skin. Suitable occlusive agents include, but are not limited to, fatty esters; fatty alcohols; mineral oils; stearic acid;
silicones; triglycerides; lanolin alcohol; squalane; silicones; and, petrolatum.
Keratin softening agents may also be used in the topical compositions of this invention.
Keratin softening agents soften the skin, as well as cosmetically improve its appearance.
Suitable keratin softening agents include, but are not limited to, urea;
lactic acid; and, allantoin.
Emulsifiers may also be used in the topical compositions of this invention.
Suitable emulsifiers include, but are not limited to, cetyl alcohol; stearic acid;
monoglyceryl stearate;
stearyl alcohol; triethanolamine acrylate; steareths; lanolin; derivatives of polyethylene glycol;
magnesium aluminum silicate; polyoxyethylene monostearate; and, propylene glycol monostearate.
Stabilizers and thickeners may also be used in the topical compositions of this invention. Suitable stabilizers and thickeners include, but are not limited to, xanthan gum;
carbomer; cetyl alcohol; acrylate co-polymers; guar gum; magnesium aluminum silicate;
glyceryl monostearate; methylcellulose; and, stearyl alcohol.
Preservatives may also be used in the topical compositions of this invention.
Suitable preservatives include, but are not limited to, parabens such as methyl paraben, ethyl paraben, butyl paraben, and propyl paraben; diazolidinyl urea; EDTA; quaternium 1 ~;
glycasii L;
phenoxyethanol; and, glutaraldehyde.
This invention also relates to methods for making the topical compositions of this invention. In general, the topical compositions of this invention are made by forming an admixture of the components of this invention. The preferred method for making the compositions of this invention is provided below in Example 1.
This invention further relates to methods for employing the topical compositions of this invention. In general the topical compositions of this invention are employed by contacting them with the skin in an amount sufficient to impart a cooling sensation to the skin.
The following Examples further describe and demonstrate embodiments within the scope of this invention. They are for illustrative purposes only, and should not be construed as limiting the scope of the invention as recited in the claims that follow. All parts and percentages set forth therein are based upon a weight percentage of the entire topical anesthetic composition.
No. INGREDIENTS PERCENT
1. + Purified Water 50-80 2. Xanthan gum NF .O1-1 3. Carbopol Ultrez 10 .O1-1 4. Edetate Disodium USP .O1-2 5. sorbitol Solution USP 1-5 6. Methyl arabe NF .1-.2 7. Trolamine NF 99% .3-.2 I 8. Mineral Oil Light 5-25 9. Lanolin Absor lion Base 5-30 10. Cet l Alcohol .2-5 1 1. Stearic Acid .2-6 12. Glvceryl Stearate Pure .5-5 13. Pro I araben .1-.2 14. But lparaben .1-.2 15. MPD .O1-2 16. Perfume 1 8 ' 17. +purified Water q.s. 1 -1. Begin mixing 1 in a stainless steel steam jacketed vessel, and slowly add 2 and 3. Mix for 30-45 minutes. Start heating to 65° C.
2. Add 4, 5, 6 and 7 to A. While mixing continue heating to 65° C.
3. Transfer 8 and 9 to a suitable stainless steel container and heat to 65° C.
4. While mixing add 10, 11, 12, 13, 14 and 15 and mix until dissolved.
5. While mixing B slowly add C to B and continue mixing for 15 minutes at 65° C. Then cool the batch to 40° C.
6. Add 16 to D. Continue mixing and further cooling to 35° C..
*Trade-mark A composition of this invention was prepared and packaged for distribution to women in an in-home use test. Each of the women taking part was given a sample of prototype product to try out for a few days at home. The results were quite positive.
They are summarized in Table l, below.
Those who took a positive attitude were favorably impressed with the results.
They said their feet felt soothed and relaxed, cooled and refreshed. The very act of massaging their feet with the product was said to be very pleasant.
Some of those tested were pleased to report that their feet were already showing the benefit of using the new product. They now had feet that were less red and sore with fewer rough patches around the heels: The skin felt softer, and even the corns felt better.
Number of Interviews:
Extremely good 10 Ve Good 11 Evaluation: Good 12 Avera a 1 Poor
Preferably fragrances from natural sources are used in the compositions of this invention. These fragrances include, but are not limited to, peppermint, eucalyptol, rosewood, lavender, grapefruit, patchouli, geranium, and rosemary. The amount of fragrance used is sufficient to impart an acceptable scent to the composition.
Humectants may also be used in the topical compositions of this invention.
Humectants promote retention of water due to their hygroscopicity, thereby easing the feeling of dryness. Suitable humectants include, but are not limited to, propylene glycol; glycerin;
sorbitol; butylene glycol; hexylene glycol; amino acids; and aloe vera.
Occlusive agents may also be used in the topical compositions of this invention.
Occlusive agents are substances that promote retention of water due to their hydrophobicity, thereby preventing water loss from the skin. Suitable occlusive agents include, but are not limited to, fatty esters; fatty alcohols; mineral oils; stearic acid;
silicones; triglycerides; lanolin alcohol; squalane; silicones; and, petrolatum.
Keratin softening agents may also be used in the topical compositions of this invention.
Keratin softening agents soften the skin, as well as cosmetically improve its appearance.
Suitable keratin softening agents include, but are not limited to, urea;
lactic acid; and, allantoin.
Emulsifiers may also be used in the topical compositions of this invention.
Suitable emulsifiers include, but are not limited to, cetyl alcohol; stearic acid;
monoglyceryl stearate;
stearyl alcohol; triethanolamine acrylate; steareths; lanolin; derivatives of polyethylene glycol;
magnesium aluminum silicate; polyoxyethylene monostearate; and, propylene glycol monostearate.
Stabilizers and thickeners may also be used in the topical compositions of this invention. Suitable stabilizers and thickeners include, but are not limited to, xanthan gum;
carbomer; cetyl alcohol; acrylate co-polymers; guar gum; magnesium aluminum silicate;
glyceryl monostearate; methylcellulose; and, stearyl alcohol.
Preservatives may also be used in the topical compositions of this invention.
Suitable preservatives include, but are not limited to, parabens such as methyl paraben, ethyl paraben, butyl paraben, and propyl paraben; diazolidinyl urea; EDTA; quaternium 1 ~;
glycasii L;
phenoxyethanol; and, glutaraldehyde.
This invention also relates to methods for making the topical compositions of this invention. In general, the topical compositions of this invention are made by forming an admixture of the components of this invention. The preferred method for making the compositions of this invention is provided below in Example 1.
This invention further relates to methods for employing the topical compositions of this invention. In general the topical compositions of this invention are employed by contacting them with the skin in an amount sufficient to impart a cooling sensation to the skin.
The following Examples further describe and demonstrate embodiments within the scope of this invention. They are for illustrative purposes only, and should not be construed as limiting the scope of the invention as recited in the claims that follow. All parts and percentages set forth therein are based upon a weight percentage of the entire topical anesthetic composition.
No. INGREDIENTS PERCENT
1. + Purified Water 50-80 2. Xanthan gum NF .O1-1 3. Carbopol Ultrez 10 .O1-1 4. Edetate Disodium USP .O1-2 5. sorbitol Solution USP 1-5 6. Methyl arabe NF .1-.2 7. Trolamine NF 99% .3-.2 I 8. Mineral Oil Light 5-25 9. Lanolin Absor lion Base 5-30 10. Cet l Alcohol .2-5 1 1. Stearic Acid .2-6 12. Glvceryl Stearate Pure .5-5 13. Pro I araben .1-.2 14. But lparaben .1-.2 15. MPD .O1-2 16. Perfume 1 8 ' 17. +purified Water q.s. 1 -1. Begin mixing 1 in a stainless steel steam jacketed vessel, and slowly add 2 and 3. Mix for 30-45 minutes. Start heating to 65° C.
2. Add 4, 5, 6 and 7 to A. While mixing continue heating to 65° C.
3. Transfer 8 and 9 to a suitable stainless steel container and heat to 65° C.
4. While mixing add 10, 11, 12, 13, 14 and 15 and mix until dissolved.
5. While mixing B slowly add C to B and continue mixing for 15 minutes at 65° C. Then cool the batch to 40° C.
6. Add 16 to D. Continue mixing and further cooling to 35° C..
*Trade-mark A composition of this invention was prepared and packaged for distribution to women in an in-home use test. Each of the women taking part was given a sample of prototype product to try out for a few days at home. The results were quite positive.
They are summarized in Table l, below.
Those who took a positive attitude were favorably impressed with the results.
They said their feet felt soothed and relaxed, cooled and refreshed. The very act of massaging their feet with the product was said to be very pleasant.
Some of those tested were pleased to report that their feet were already showing the benefit of using the new product. They now had feet that were less red and sore with fewer rough patches around the heels: The skin felt softer, and even the corns felt better.
Number of Interviews:
Extremely good 10 Ve Good 11 Evaluation: Good 12 Avera a 1 Poor
Claims (11)
1. A topical composition comprising a moisturizer and 3-1-menthoxy propane 1,2-diol wherein said 3-1-menthoxy propane 1,2-diol is in an amount effective for said composition to provide a cooling sensation to the skin.
2. The topical composition of claim 1 wherein said MPD is present in an amount of from about 0.01 % to about 2.0% weight/volume of the total composition.
3. The topical composition of claim 2 wherein said MPD is present in an amount of from about 0.1 % to about 1.0% weight/volume of the total composition.
4. The topical composition of claim 3 wherein said MPD is present in an amount of from about 0.3% to about 0.6% weight/volume of the total composition.
5. The topical composition of claim 1 further comprising fragrances provided by naturally occurring essential oils.
6. The topical composition of claim 5 wherein said fragrances are selected from the group consisting of eucalyptus, peppermint oils, and menthol.
7. A method for preparing a topical composition for cooling the skin which comprises the steps of admixing the following ingredients:
a) a moisturizer b) 3-1-menthoxy propane 1,2-diol wherein said 3-1-menthoxy propane 1,2-diol is in an amount effective for said composition to provide a cooling sensation to the skin.
a) a moisturizer b) 3-1-menthoxy propane 1,2-diol wherein said 3-1-menthoxy propane 1,2-diol is in an amount effective for said composition to provide a cooling sensation to the skin.
8. A method for cooling the skin comprising the step of applying to the skin a topical composition comprising a moisturizer and 3-1-menthoxy propane 1,2-diol wherein said 3-1-menthoxy propane 1,2-diol is in an amount effective for said composition to provide a cooling sensation to the skin.
9. A topical composition for cooling and refreshing the feet comprising a moisturizer and 3-1-menthoxy propane 1,2-diol wherein said 3-1-menthoxy propane 1,2-diol is in an amount effective for said composition to provide a cooling sensation to the skin.
10. The topical composition of claim 9 further comprising fragrances provided by naturally occurring essential oils.
11. The method of Claim 8 wherein the skin is the skin of human feet.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1243396P | 1996-02-28 | 1996-02-28 | |
| US60/012,433 | 1996-02-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2198667A1 CA2198667A1 (en) | 1997-08-28 |
| CA2198667C true CA2198667C (en) | 2006-01-10 |
Family
ID=21754958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2198667 Expired - Fee Related CA2198667C (en) | 1996-02-28 | 1997-02-27 | Cooling sensation composition comprising 3-1-menthoxy propane 1, 2-diol |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2198667C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008195710A (en) * | 2007-01-17 | 2008-08-28 | Takasago Internatl Corp | Moisturizing composition |
-
1997
- 1997-02-27 CA CA 2198667 patent/CA2198667C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008195710A (en) * | 2007-01-17 | 2008-08-28 | Takasago Internatl Corp | Moisturizing composition |
| EP1946743A3 (en) * | 2007-01-17 | 2011-04-06 | Takasago International Corporation | Humectant composition |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2198667A1 (en) | 1997-08-28 |
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