BRPI1012922A2 - polipeptídeo de b-glicosidase variante, vetor de expressão, célula hospedeira, método de produção de polipeptídeo de b-glicosidase variante, composição enzimática, método de conversão de um substrato de biomassa em açucar fermentável e método de produção de álcool - Google Patents
polipeptídeo de b-glicosidase variante, vetor de expressão, célula hospedeira, método de produção de polipeptídeo de b-glicosidase variante, composição enzimática, método de conversão de um substrato de biomassa em açucar fermentável e método de produção de álcoolInfo
- Publication number
- BRPI1012922A2 BRPI1012922A2 BRPI1012922A BRPI1012922A BRPI1012922A2 BR PI1012922 A2 BRPI1012922 A2 BR PI1012922A2 BR PI1012922 A BRPI1012922 A BR PI1012922A BR PI1012922 A BRPI1012922 A BR PI1012922A BR PI1012922 A2 BRPI1012922 A2 BR PI1012922A2
- Authority
- BR
- Brazil
- Prior art keywords
- glycosidase
- production method
- variant
- polypeptide
- converting
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 2
- 229920001184 polypeptide Polymers 0.000 title 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 239000002028 Biomass Substances 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 1
- 230000002255 enzymatic effect Effects 0.000 title 1
- 239000013604 expression vector Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000758 substrate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18756509P | 2009-06-16 | 2009-06-16 | |
| US21802009P | 2009-06-17 | 2009-06-17 | |
| PCT/US2010/038879 WO2010148128A1 (en) | 2009-06-16 | 2010-06-16 | Beta-glucosidase variant enzymes and related polynucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1012922A2 true BRPI1012922A2 (pt) | 2016-10-11 |
Family
ID=43306753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1012922A BRPI1012922A2 (pt) | 2009-06-16 | 2010-06-16 | polipeptídeo de b-glicosidase variante, vetor de expressão, célula hospedeira, método de produção de polipeptídeo de b-glicosidase variante, composição enzimática, método de conversão de um substrato de biomassa em açucar fermentável e método de produção de álcool |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8357523B2 (pt) |
| EP (1) | EP2443139B1 (pt) |
| BR (1) | BRPI1012922A2 (pt) |
| CA (1) | CA2762616C (pt) |
| WO (1) | WO2010148128A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8916366B2 (en) * | 2009-11-20 | 2014-12-23 | Codexis, Inc. | Multi-cellulase enzyme compositions for hydrolysis of cellulosic biomass |
| EP2576775A1 (en) * | 2010-06-07 | 2013-04-10 | Yeda Research and Development Co. Ltd. | Modified cellulases with enhanced thermostability |
| EP2606131B1 (en) | 2010-08-20 | 2017-03-08 | Codexis, Inc. | Use of glycoside hydrolase 61 family proteins in processing of cellulose |
| CN103429738A (zh) * | 2011-03-24 | 2013-12-04 | 旭硝子株式会社 | 裂殖酵母属酵母的转化体、该转化体的制造方法、β-葡糖苷酶的制造方法及纤维素的降解方法 |
| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
| CN117126823B (zh) * | 2023-09-01 | 2024-03-29 | 华南理工大学 | 一种酮还原酶突变体及其应用 |
| CN118165960B (zh) * | 2024-03-25 | 2025-03-25 | 南京大学 | 一种内切β-1,4-葡聚糖酶突变体及其基因、载体和制备方法 |
| CN118910014B (zh) * | 2024-09-03 | 2025-04-25 | 广州青囊生物科技有限公司 | 一种生产稀有人参皂苷CK的β-葡萄糖苷酶突变体及其应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3009104C2 (de) | 1980-03-10 | 1990-10-04 | Odenwald-Chemie GmbH, 6901 Schönau | Verwendung eines Epoxydharzes zur Herstellung von feuerhemmenden Schichten oder Überzügen und Verfahren zur Herstellung derselben |
| CA1338400C (en) | 1983-08-31 | 1996-06-18 | David H. Gelfand | Recombinant fungal cellulases |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5776757A (en) | 1988-03-24 | 1998-07-07 | Novo Nordisk A/S | Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof |
| US5426039A (en) | 1993-09-08 | 1995-06-20 | Bio-Rad Laboratories, Inc. | Direct molecular cloning of primer extended DNA containing an alkane diol |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| FI104465B (fi) | 1995-06-14 | 2000-02-15 | Valio Oy | Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö |
| US7883872B2 (en) * | 1996-10-10 | 2011-02-08 | Dyadic International (Usa), Inc. | Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose |
| US6265204B1 (en) | 1997-01-17 | 2001-07-24 | Genencor International, Inc. | DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi |
| HUP9701446A1 (hu) | 1997-08-27 | 1999-05-28 | Phylaxia-Pharma Gyógyszer-, Oltóanyag és Agrobiológiai Készítményeket Gyártó és Forgalmazó Rt. | Eljárás a talaj mikroorganizmus populációjának előnyös kialakítására |
| JP4221100B2 (ja) | 1999-01-13 | 2009-02-12 | エルピーダメモリ株式会社 | 半導体装置 |
| NZ519043A (en) | 1999-11-19 | 2006-12-22 | Yissum Res Dev Co | Nucleic acid comprising a gene derived from Aspergillus niger that encodes a polypeptide that has a beta-glucosidase catalytic activity |
| WO2001075767A2 (en) | 2000-03-30 | 2001-10-11 | Maxygen, Inc. | In silico cross-over site selection |
| HUE028524T2 (en) | 2002-03-01 | 2016-12-28 | Codexis Mayflower Holdings Llc | Procedures, systems and software for identifying functional biomolecules |
| US7407788B2 (en) | 2002-11-21 | 2008-08-05 | Danisco A/S, Genencor Division | BGL7 beta-glucosidase and nucleic acids encoding the same |
| EP1682656B1 (en) | 2003-10-28 | 2013-09-18 | Novozymes Inc. | Polypeptides having beta-glucosidase activity and polynucleotides encoding same |
| WO2007075899A2 (en) | 2005-12-21 | 2007-07-05 | Maxygen, Inc. | Dual agonist compounds and uses thereof |
| CN101528917B (zh) | 2006-10-02 | 2015-07-29 | 科德克希思公司 | 用于制备立体异构纯的他汀类及其合成中间体的组合物和方法 |
| CA2726850C (en) | 2008-06-13 | 2015-06-02 | Codexis, Inc. | Method of synthesizing polynucleotide variants |
| US20090312196A1 (en) | 2008-06-13 | 2009-12-17 | Codexis, Inc. | Method of synthesizing polynucleotide variants |
-
2010
- 2010-06-16 CA CA2762616A patent/CA2762616C/en not_active Expired - Fee Related
- 2010-06-16 US US12/816,989 patent/US8357523B2/en not_active Expired - Fee Related
- 2010-06-16 WO PCT/US2010/038879 patent/WO2010148128A1/en not_active Ceased
- 2010-06-16 BR BRPI1012922A patent/BRPI1012922A2/pt not_active Application Discontinuation
- 2010-06-16 EP EP10790144.9A patent/EP2443139B1/en not_active Not-in-force
-
2012
- 2012-12-19 US US13/719,431 patent/US8530201B2/en not_active Expired - Fee Related
-
2013
- 2013-09-05 US US14/018,531 patent/US8715975B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2443139A1 (en) | 2012-04-25 |
| WO2010148128A1 (en) | 2010-12-23 |
| EP2443139B1 (en) | 2016-08-10 |
| CA2762616A1 (en) | 2010-12-23 |
| US8357523B2 (en) | 2013-01-22 |
| CA2762616C (en) | 2015-08-18 |
| EP2443139A4 (en) | 2013-02-27 |
| US8715975B2 (en) | 2014-05-06 |
| US20140004586A1 (en) | 2014-01-02 |
| US20100317059A1 (en) | 2010-12-16 |
| US20130095530A1 (en) | 2013-04-18 |
| US8530201B2 (en) | 2013-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
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| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |