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BRPI1016151A2 - processo para produção de tioéster peptídeo - Google Patents

processo para produção de tioéster peptídeo

Info

Publication number
BRPI1016151A2
BRPI1016151A2 BRPI1016151A BRPI1016151A BRPI1016151A2 BR PI1016151 A2 BRPI1016151 A2 BR PI1016151A2 BR PI1016151 A BRPI1016151 A BR PI1016151A BR PI1016151 A BRPI1016151 A BR PI1016151A BR PI1016151 A2 BRPI1016151 A2 BR PI1016151A2
Authority
BR
Brazil
Prior art keywords
peptide thioester
production
thioester production
peptide
thioester
Prior art date
Application number
BRPI1016151A
Other languages
English (en)
Inventor
Kazuyuki Ishii
ryo Okamoto
Sakamoto Izumi
Yasuhiro Kajihara
Original Assignee
Otsuka Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd filed Critical Otsuka Chemical Co Ltd
Publication of BRPI1016151A2 publication Critical patent/BRPI1016151A2/pt
Publication of BRPI1016151B1 publication Critical patent/BRPI1016151B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI1016151-1A 2009-06-26 2010-06-21 processo para produção de um tioéster de peptídeo, processos para a produção de um polipeptídeo, processo para a produção de um segundo intermediário utilizado para o processo para a produção do tioéster de peptídeo e processo para a remoção de uma marca para a purificação adicionada a um lado terminal c de uma proteína recombinante BRPI1016151B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009151713 2009-06-26
JP2009-151713 2009-06-26
PCT/JP2010/060443 WO2010150730A1 (ja) 2009-06-26 2010-06-21 ペプチドチオエステル体の製造方法

Publications (2)

Publication Number Publication Date
BRPI1016151A2 true BRPI1016151A2 (pt) 2016-04-19
BRPI1016151B1 BRPI1016151B1 (pt) 2021-01-19

Family

ID=43386499

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1016151-1A BRPI1016151B1 (pt) 2009-06-26 2010-06-21 processo para produção de um tioéster de peptídeo, processos para a produção de um polipeptídeo, processo para a produção de um segundo intermediário utilizado para o processo para a produção do tioéster de peptídeo e processo para a remoção de uma marca para a purificação adicionada a um lado terminal c de uma proteína recombinante

Country Status (13)

Country Link
US (2) US8642725B2 (pt)
EP (1) EP2450364B1 (pt)
JP (1) JP5730197B2 (pt)
KR (1) KR101676515B1 (pt)
CN (1) CN102803286B (pt)
AU (1) AU2010263701B2 (pt)
BR (1) BRPI1016151B1 (pt)
CA (1) CA2766040C (pt)
DK (1) DK2450364T3 (pt)
RU (1) RU2529998C2 (pt)
SG (1) SG176300A1 (pt)
TW (1) TWI485156B (pt)
WO (1) WO2010150730A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6186278B2 (ja) * 2011-09-26 2017-08-23 株式会社糖鎖工学研究所 Ncl法に適した、ポリペプチド断片の効率的な製造方法
WO2022143532A1 (zh) * 2020-12-28 2022-07-07 江苏金斯瑞生物科技有限公司 一种肽硫酯及其首尾酰胺环肽的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2539483A (en) * 1945-03-28 1951-01-30 Simon L Ruskin Urea ascorbate and complexes containing the same and process for their manufacture
FR1454653A (fr) * 1964-10-29 1966-02-11 Yissum Res Dev Co Procédé de production de peptides
SI0832096T1 (en) 1995-05-04 2001-12-31 Scripps Research Inst Synthesis of proteins by native chemical ligation
GB0113657D0 (en) * 2001-06-05 2001-07-25 Geneprot Inc Improved native chemical ligation with three or more components
WO2007043615A1 (ja) * 2005-10-14 2007-04-19 Osaka University ペプチドエステル試薬、およびそのライゲーションまたはチオエステル化合物の製造のための使用
AU2007232742B2 (en) * 2006-03-29 2012-02-02 Glytech, Inc. Method for production of peptide thioester compound
WO2009017154A1 (ja) * 2007-07-31 2009-02-05 Otsuka Chemical Co., Ltd. ペプチドの製造方法
WO2009042668A2 (en) * 2007-09-24 2009-04-02 Achillion Pharmaceuticals, Inc. Urea-containing peptides as inhibitors of viral replication

Also Published As

Publication number Publication date
EP2450364B1 (en) 2016-11-09
AU2010263701B2 (en) 2014-01-23
RU2529998C2 (ru) 2014-10-10
CN102803286A (zh) 2012-11-28
US20140249294A1 (en) 2014-09-04
JPWO2010150730A1 (ja) 2012-12-10
TW201100445A (en) 2011-01-01
EP2450364A4 (en) 2014-07-02
TWI485156B (zh) 2015-05-21
CA2766040C (en) 2018-05-01
JP5730197B2 (ja) 2015-06-03
SG176300A1 (en) 2012-01-30
CN102803286B (zh) 2015-01-14
KR20120039637A (ko) 2012-04-25
US20120178905A1 (en) 2012-07-12
BRPI1016151B1 (pt) 2021-01-19
US8642725B2 (en) 2014-02-04
KR101676515B1 (ko) 2016-11-15
RU2012102519A (ru) 2013-08-10
EP2450364A1 (en) 2012-05-09
CA2766040A1 (en) 2010-12-29
WO2010150730A1 (ja) 2010-12-29
US9127041B2 (en) 2015-09-08
AU2010263701A1 (en) 2011-12-15
DK2450364T3 (en) 2017-01-16

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: GLYTECH, INC. (JP)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 19/01/2021, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2780 DE 16-04-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.