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BRPI1009366A2 - método e sistema de detecção de analito em tecido sólido in vitro - Google Patents

método e sistema de detecção de analito em tecido sólido in vitro

Info

Publication number
BRPI1009366A2
BRPI1009366A2 BRPI1009366A BRPI1009366A BRPI1009366A2 BR PI1009366 A2 BRPI1009366 A2 BR PI1009366A2 BR PI1009366 A BRPI1009366 A BR PI1009366A BR PI1009366 A BRPI1009366 A BR PI1009366A BR PI1009366 A2 BRPI1009366 A2 BR PI1009366A2
Authority
BR
Brazil
Prior art keywords
detection method
analyte detection
solid tissue
tissue analyte
vitro solid
Prior art date
Application number
BRPI1009366A
Other languages
English (en)
Inventor
Devin Mccormack
John A Viator
Paul S Dale
Original Assignee
Univ Missouri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Missouri filed Critical Univ Missouri
Publication of BRPI1009366A2 publication Critical patent/BRPI1009366A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Clinical applications
    • A61B8/0833—Clinical applications involving detecting or locating foreign bodies or organic structures
    • A61B8/0841—Clinical applications involving detecting or locating foreign bodies or organic structures for locating instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4477—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device using several separate ultrasound transducers or probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G01N29/24—Probes
    • G01N29/2418—Probes using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/13—Tomography
    • A61B8/15—Transmission-tomography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/028—Material parameters
    • G01N2291/02809—Concentration of a compound, e.g. measured by a surface mass change
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Acoustics & Sound (AREA)
  • Gynecology & Obstetrics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
BRPI1009366A 2009-04-20 2010-04-20 método e sistema de detecção de analito em tecido sólido in vitro BRPI1009366A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17088009P 2009-04-20 2009-04-20
PCT/US2010/031731 WO2010123883A2 (en) 2009-04-20 2010-04-20 Photoacoustic detection of analytes in solid tissue and detection system

Publications (1)

Publication Number Publication Date
BRPI1009366A2 true BRPI1009366A2 (pt) 2016-03-08

Family

ID=43011716

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009366A BRPI1009366A2 (pt) 2009-04-20 2010-04-20 método e sistema de detecção de analito em tecido sólido in vitro

Country Status (8)

Country Link
US (1) US20100285518A1 (pt)
EP (1) EP2422185A4 (pt)
JP (1) JP5555765B2 (pt)
CN (1) CN102460117A (pt)
AU (1) AU2010239360A1 (pt)
BR (1) BRPI1009366A2 (pt)
CA (1) CA2759722A1 (pt)
WO (1) WO2010123883A2 (pt)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101918811B (zh) 2007-10-25 2013-07-31 圣路易斯华盛顿大学 具有光学横向分辨率的共焦光声显微镜
EP2352422A4 (en) * 2008-09-10 2015-08-12 Endra Inc DEVICE FOR PHOTOACOUS IMAGING
WO2010080991A2 (en) 2009-01-09 2010-07-15 Washington University In St. Louis Miniaturized photoacoustic imaging apparatus including a rotatable reflector
JP5538856B2 (ja) * 2009-12-11 2014-07-02 キヤノン株式会社 光音響装置
WO2011127428A2 (en) 2010-04-09 2011-10-13 Washington University Quantification of optical absorption coefficients using acoustic spectra in photoacoustic tomography
JP5553672B2 (ja) * 2010-04-26 2014-07-16 キヤノン株式会社 音響波測定装置および音響波測定方法
US9289191B2 (en) 2011-10-12 2016-03-22 Seno Medical Instruments, Inc. System and method for acquiring optoacoustic data and producing parametric maps thereof
US8686335B2 (en) 2011-12-31 2014-04-01 Seno Medical Instruments, Inc. System and method for adjusting the light output of an optoacoustic imaging system
US10271733B2 (en) * 2010-12-22 2019-04-30 Koninklijke Philips N.V. Photo-acoustic signal enhancement with microbubble-based contrast agents
US8997572B2 (en) 2011-02-11 2015-04-07 Washington University Multi-focus optical-resolution photoacoustic microscopy with ultrasonic array detection
JP5932243B2 (ja) * 2011-05-31 2016-06-08 キヤノン株式会社 装置
EP2766851B1 (en) * 2011-10-12 2019-11-27 Seno Medical Instruments, Inc. System and method for acquiring optoacoustic data and producing parametric maps thereof
US9055869B2 (en) 2011-10-28 2015-06-16 Covidien Lp Methods and systems for photoacoustic signal processing
US9757092B2 (en) 2011-11-02 2017-09-12 Seno Medical Instruments, Inc. Method for dual modality optoacoustic imaging
US10433732B2 (en) 2011-11-02 2019-10-08 Seno Medical Instruments, Inc. Optoacoustic imaging system having handheld probe utilizing optically reflective material
US20130289381A1 (en) 2011-11-02 2013-10-31 Seno Medical Instruments, Inc. Dual modality imaging system for coregistered functional and anatomical mapping
US20130116538A1 (en) 2011-11-02 2013-05-09 Seno Medical Instruments, Inc. Optoacoustic imaging systems and methods with enhanced safety
US9733119B2 (en) 2011-11-02 2017-08-15 Seno Medical Instruments, Inc. Optoacoustic component utilization tracking
US9743839B2 (en) 2011-11-02 2017-08-29 Seno Medical Instruments, Inc. Playback mode in an optoacoustic imaging system
US9814394B2 (en) 2011-11-02 2017-11-14 Seno Medical Instruments, Inc. Noise suppression in an optoacoustic system
US20140005544A1 (en) 2011-11-02 2014-01-02 Seno Medical Instruments, Inc. System and method for providing selective channel sensitivity in an optoacoustic imaging system
US20130338475A1 (en) 2012-06-13 2013-12-19 Seno Medical Instruments, Inc. Optoacoustic imaging system with fiber optic cable
US11287309B2 (en) 2011-11-02 2022-03-29 Seno Medical Instruments, Inc. Optoacoustic component utilization tracking
US9730587B2 (en) 2011-11-02 2017-08-15 Seno Medical Instruments, Inc. Diagnostic simulator
US9445786B2 (en) 2011-11-02 2016-09-20 Seno Medical Instruments, Inc. Interframe energy normalization in an optoacoustic imaging system
US11191435B2 (en) 2013-01-22 2021-12-07 Seno Medical Instruments, Inc. Probe with optoacoustic isolator
WO2013158154A1 (en) * 2011-11-04 2013-10-24 Seno Medical Instruments, Inc. System and method for adjusting the light output of an optoacoustic imaging system
US8886294B2 (en) 2011-11-30 2014-11-11 Covidien Lp Methods and systems for photoacoustic monitoring using indicator dilution
US9186068B2 (en) 2011-12-05 2015-11-17 Covidien Lp Methods and systems for photoacoustic monitoring using hypertonic and isotonic indicator dilutions
US9131852B2 (en) 2011-12-05 2015-09-15 Covidien Lp Methods and systems for photoacoustic monitoring using indicator dilution
WO2013086293A1 (en) * 2011-12-08 2013-06-13 Washington University In vivo label-free histology by photoacoustic microscopy of cell nuclei
US8891088B2 (en) 2012-01-20 2014-11-18 The Curators Of The University Of Missouri Total internal reflection photoacoustic spectroscopy
EP2820429B1 (en) 2012-03-02 2021-02-24 LAXCO, Inc. Multichannel analytical instruments for use with specimen holders
SG11201405548RA (en) 2012-03-09 2014-10-30 Seno Medical Instr Inc Statistical mapping in an optoacoustic imaging system
JP6124503B2 (ja) * 2012-03-26 2017-05-10 キヤノン株式会社 被検体情報取得装置
US8885155B2 (en) * 2012-04-30 2014-11-11 Covidien Lp Combined light source photoacoustic system
US11020006B2 (en) 2012-10-18 2021-06-01 California Institute Of Technology Transcranial photoacoustic/thermoacoustic tomography brain imaging informed by adjunct image data
DE102012223651A1 (de) * 2012-12-18 2014-06-18 Carl Zeiss Ag Abbildungsverfahren für ein Resektat und Bilderzeugungsvorrichtung zum Durchführen eines solchen Abbildungsverfahrens
US11137375B2 (en) 2013-11-19 2021-10-05 California Institute Of Technology Systems and methods of grueneisen-relaxation photoacoustic microscopy and photoacoustic wavefront shaping
CN104146685B (zh) * 2014-08-27 2016-04-13 华南师范大学 一种基于光声原理的皮肤色素沉着成像装置
CN104161520A (zh) * 2014-08-27 2014-11-26 华南师范大学 一种基于光致声效应原理的测定表皮黑色素浓度的方法及其装置
US10408934B2 (en) * 2015-08-19 2019-09-10 Canon Kabushiki Kaisha Object information acquiring apparatus
CN105342570B (zh) * 2015-12-08 2019-03-29 重庆医科大学 一种前哨淋巴结的定位方法与定位仪
US12036000B2 (en) 2016-05-27 2024-07-16 The Regents Of The University Of Michigan Method of photoacoustic imaging intraocular tumors including back-projection reconstruction to measure heterogeneity
WO2018209046A1 (en) 2017-05-10 2018-11-15 Washington University Snapshot photoacoustic photography using an ergodic relay
US10335036B2 (en) 2017-11-22 2019-07-02 Hi Llc Pulsed ultrasound modulated optical tomography using lock-in camera
US10016137B1 (en) 2017-11-22 2018-07-10 Hi Llc System and method for simultaneously detecting phase modulated optical signals
US10368752B1 (en) 2018-03-08 2019-08-06 Hi Llc Devices and methods to convert conventional imagers into lock-in cameras
US11206985B2 (en) 2018-04-13 2021-12-28 Hi Llc Non-invasive optical detection systems and methods in highly scattering medium
US11857316B2 (en) 2018-05-07 2024-01-02 Hi Llc Non-invasive optical detection system and method
US11530979B2 (en) 2018-08-14 2022-12-20 California Institute Of Technology Multifocal photoacoustic microscopy through an ergodic relay
US11592652B2 (en) 2018-09-04 2023-02-28 California Institute Of Technology Enhanced-resolution infrared photoacoustic microscopy and spectroscopy
RU2732470C2 (ru) * 2018-12-07 2020-09-17 Федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургский государственный университет (СПбГУ)" Устройство для лазерно-акустического контроля твердых и жидких сред
US11369280B2 (en) 2019-03-01 2022-06-28 California Institute Of Technology Velocity-matched ultrasonic tagging in photoacoustic flowgraphy
WO2021048951A1 (ja) * 2019-09-11 2021-03-18 日本電信電話株式会社 光音響プローブ
US11986269B2 (en) 2019-11-05 2024-05-21 California Institute Of Technology Spatiotemporal antialiasing in photoacoustic computed tomography
US20240215832A1 (en) * 2021-05-21 2024-07-04 The Regents Of The University Of California A photoacoustic patch for three-dimensional imaging of hemoglobin and core temperature
US12504363B2 (en) 2021-08-17 2025-12-23 California Institute Of Technology Three-dimensional contoured scanning photoacoustic imaging and virtual staining
CN115201134B (zh) * 2022-09-15 2022-12-27 吉林大学第一医院 一种抗白皮杉醇干扰的肌酐检测试剂盒及其应用

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5085080A (en) * 1990-10-05 1992-02-04 Micron Technology, Inc. Temperature and pressure measuring technique using the photoacoustic effect and mechanical resonance
JPH04213999A (ja) * 1990-12-12 1992-08-05 Nec Corp 受波器
US5152749A (en) * 1991-06-28 1992-10-06 American Medical Systems, Inc. Instrument placement apparatus
US5781294A (en) * 1991-12-24 1998-07-14 Hitachi, Ltd. Method and apparatus for detecting photoacoustic signal to detect surface and subsurface information of the specimen
DE69333058T2 (de) * 1992-10-27 2003-12-24 Tdk Corp., Tokio/Tokyo Piezoelektrischer Wandler
US5720894A (en) * 1996-01-11 1998-02-24 The Regents Of The University Of California Ultrashort pulse high repetition rate laser system for biological tissue processing
US5840023A (en) * 1996-01-31 1998-11-24 Oraevsky; Alexander A. Optoacoustic imaging for medical diagnosis
US5713356A (en) * 1996-10-04 1998-02-03 Optosonics, Inc. Photoacoustic breast scanner
GB9704737D0 (en) * 1997-03-07 1997-04-23 Optel Instr Limited Biological measurement system
US6041020A (en) * 1997-04-21 2000-03-21 University Of Delaware Gas-coupled laser acoustic detection
US7039446B2 (en) * 2001-01-26 2006-05-02 Sensys Medical, Inc. Indirect measurement of tissue analytes through tissue properties
US5941821A (en) * 1997-11-25 1999-08-24 Trw Inc. Method and apparatus for noninvasive measurement of blood glucose by photoacoustics
US6108096A (en) * 1997-12-22 2000-08-22 Nikon Corporation Light absorption measurement apparatus and methods
JP2004501712A (ja) * 2000-07-05 2004-01-22 アストロン　クリニカ　リミテッド 表皮診断支援装置
US20020026937A1 (en) * 2000-08-28 2002-03-07 Mault James R. Respiratory gas sensors in folw path
US20050085725A1 (en) * 2001-08-09 2005-04-21 Ron Nagar Photoacoustic assay and imaging system
JP2003290126A (ja) * 2002-03-29 2003-10-14 Olympus Optical Co Ltd センチネルリンパ節検出装置及びその方法
CN1168980C (zh) * 2002-04-03 2004-09-29 华南师范大学 用探测超声束测量生物组织中光致声信号的方法及其装置
US7322972B2 (en) * 2002-04-10 2008-01-29 The Regents Of The University Of California In vivo port wine stain, burn and melanin depth determination using a photoacoustic probe
US7224465B2 (en) * 2002-10-15 2007-05-29 University Of Maryland Fiber tip based sensor system for measurements of pressure gradient, air particle velocity and acoustic intensity
EP1585440A1 (en) * 2003-01-13 2005-10-19 Glucon Inc. Photoacoustic assay method and apparatus
DK1593091T3 (da) * 2003-01-25 2013-10-28 Seno Medical Instr Inc Optoakustisk afbildning med høj kontrast ved anvendelse af ikke-sfæriske nanopartikler
CN1470218A (zh) * 2003-06-18 2004-01-28 华南师范大学 多元阵列电子扫描生物组织光声层析成像的方法及其装置
US20050070803A1 (en) * 2003-09-30 2005-03-31 Cullum Brian M. Multiphoton photoacoustic spectroscopy system and method
US7176600B2 (en) * 2003-12-18 2007-02-13 Palo Alto Research Center Incorporated Poling system for piezoelectric diaphragm structures
WO2005064338A1 (en) * 2003-12-23 2005-07-14 University Of Florida Research Foundation, Inc. Microparticles for use in diagnostic methods
CN100434042C (zh) * 2004-01-06 2008-11-19 华南师范大学 生物组织光学和超声的采集和层析成像的方法及其装置
JP4643153B2 (ja) * 2004-02-06 2011-03-02 株式会社東芝 非侵襲生体情報映像装置
AT414212B (de) * 2004-07-20 2006-10-15 Upper Austrian Res Gmbh Thermoakustisches tomographieverfahren und thermoakustischer tomograph
US7491502B2 (en) * 2004-12-17 2009-02-17 The General Hospital Corporation In vivo flow cytometry system and method
US20060184042A1 (en) * 2005-01-22 2006-08-17 The Texas A&M University System Method, system and apparatus for dark-field reflection-mode photoacoustic tomography
CN100446730C (zh) * 2005-12-16 2008-12-31 华南师范大学 基于声透镜的光声成像和层析成像方法及其装置
US20070220979A1 (en) * 2006-03-21 2007-09-27 Ut-Battelle Llc Method and apparatus for remote sensing utilizing a reverse photoacoustic effect
JP4444228B2 (ja) * 2006-03-27 2010-03-31 日本電信電話株式会社 成分濃度測定装置
ES2708573T3 (es) * 2006-07-11 2019-04-10 Univ Missouri Dispositivo y método de detección fotoacústica
US8501099B2 (en) * 2006-07-11 2013-08-06 The Curators Of The University Of Missouri Photo-acoustic detection device and method
US8877051B2 (en) * 2006-07-21 2014-11-04 Waters Technologies Corporation Time delay for sample collection in chromatography systems
JP5219440B2 (ja) * 2007-09-12 2013-06-26 キヤノン株式会社 測定装置

Also Published As

Publication number Publication date
JP5555765B2 (ja) 2014-07-23
US20100285518A1 (en) 2010-11-11
CA2759722A1 (en) 2010-10-28
WO2010123883A2 (en) 2010-10-28
EP2422185A2 (en) 2012-02-29
AU2010239360A1 (en) 2011-11-24
EP2422185A4 (en) 2013-02-13
CN102460117A (zh) 2012-05-16
WO2010123883A3 (en) 2011-02-24
JP2012524285A (ja) 2012-10-11

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B25G Requested change of headquarter approved

Owner name: THE CURATORS OF THE UNIVERSITY OF MISSOURI (US)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2372 DE 21-06-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.