BRPI1008317A2 - "anticorpos anti-cemx capazes de se ligar a mige humana em linfócitos b" - Google Patents

"anticorpos anti-cemx capazes de se ligar a mige humana em linfócitos b"

Info

Publication number: BRPI1008317A2
Authority: BR; Brazil
Prior art keywords: cemx; lymphocytes; binding; antibodies capable; human mige
Prior art date: 2009-02-25

Application number

BRPI1008317A

Other languages

English (en)

Inventor

Chang Tsewen

Chen Jiun-Bo

C. Wu Pheidias

F. Hung Alfur

Original Assignee

Academia Sinica

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-02-25

Filing date

2010-02-25

Publication date

2018-03-13

2010-02-25 Application filed by Academia Sinica filed Critical Academia Sinica

2018-03-13 Publication of BRPI1008317A2 publication Critical patent/BRPI1008317A2/pt

2022-05-03 Publication of BRPI1008317B1 publication Critical patent/BRPI1008317B1/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/805—Drug, bio-affecting and body treating compositions involving IgE or IgD
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/862—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgE or IgD
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Hematology (AREA)
Diabetes (AREA)
Nutrition Science (AREA)
Urology & Nephrology (AREA)
Otolaryngology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

BRPI1008317-0A 2009-02-25 2010-02-25 Anticorpo cemx-específico ou fragmento de ligação ao antígeno do mesmo, uso do dito anticorpo ou fragmento de ligação ao antígeno para tratar doenças mediadas por ige e uso de um imunogênico ou um análogo com propriedade antigênica similar para induzir uma resposta imune em um paciente BRPI1008317B1 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US15522409P	2009-02-25	2009-02-25
US61/155,224		2009-02-25
PCT/CN2010/000232 WO2010097012A1 (en)	2009-02-25	2010-02-25	ANTI-CεmX ANTIBODIES CAPABLE OF BINDING TO HUMAN mIgE ON B LYMPHOCYTES

Publications (2)

Publication Number	Publication Date
BRPI1008317A2 true BRPI1008317A2 (pt)	2018-03-13
BRPI1008317B1 BRPI1008317B1 (pt)	2022-05-03

Family

ID=42665017

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1008317-0A BRPI1008317B1 (pt)	2009-02-25	2010-02-25	Anticorpo cemx-específico ou fragmento de ligação ao antígeno do mesmo, uso do dito anticorpo ou fragmento de ligação ao antígeno para tratar doenças mediadas por ige e uso de um imunogênico ou um análogo com propriedade antigênica similar para induzir uma resposta imune em um paciente

Country Status (19)

Country	Link
US (3)	US8460664B2 (pt)
EP (1)	EP2401300B1 (pt)
JP (1)	JP5848133B2 (pt)
KR (1)	KR101529160B1 (pt)
CN (2)	CN104667271B (pt)
AU (1)	AU2010217100B2 (pt)
BR (1)	BRPI1008317B1 (pt)
DK (1)	DK2401300T3 (pt)
ES (1)	ES2665495T3 (pt)
HU (1)	HUE036920T2 (pt)
IL (1)	IL214836A (pt)
MX (1)	MX2011008971A (pt)
MY (1)	MY183134A (pt)
PL (1)	PL2401300T3 (pt)
PT (1)	PT2401300T (pt)
RU (2)	RU2550270C2 (pt)
SG (1)	SG174161A1 (pt)
WO (1)	WO2010097012A1 (pt)
ZA (1)	ZA201209640B (pt)

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2010
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- 2010-02-25 CN CN201510069440.7A patent/CN104667271B/zh active Active
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- 2010-02-25 AU AU2010217100A patent/AU2010217100B2/en active Active
- 2010-02-25 CN CN201080009485.0A patent/CN102482351B/zh active Active
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- 2010-02-25 EP EP10745796.2A patent/EP2401300B1/en active Active
- 2010-02-25 JP JP2011551394A patent/JP5848133B2/ja active Active
- 2010-02-25 KR KR1020117021979A patent/KR101529160B1/ko active Active
- 2010-02-25 PL PL10745796T patent/PL2401300T3/pl unknown
- 2010-02-25 RU RU2015109110/10A patent/RU2015109110A/ru not_active Application Discontinuation
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2013
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2014
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Also Published As

Publication number	Publication date
ZA201209640B (en)	2013-08-28
MY183134A (en)	2021-02-15
PL2401300T3 (pl)	2018-07-31
JP2013520396A (ja)	2013-06-06
EP2401300A4 (en)	2013-01-23
RU2015109110A (ru)	2015-07-20
WO2010097012A1 (en)	2010-09-02
AU2010217100B2 (en)	2014-03-27
US8460664B2 (en)	2013-06-11
HK1171766A1 (en)	2013-04-05
US8741294B2 (en)	2014-06-03
CN104667271A (zh)	2015-06-03
AU2010217100A1 (en)	2011-10-13
JP5848133B2 (ja)	2016-01-27
MX2011008971A (es)	2012-02-21
BRPI1008317B1 (pt)	2022-05-03
AU2010217100A8 (en)	2011-11-10
US20140220042A1 (en)	2014-08-07
CN102482351A (zh)	2012-05-30
CN102482351B (zh)	2015-03-18
IL214836A (en)	2015-08-31
IL214836A0 (en)	2011-11-30
EP2401300A1 (en)	2012-01-04
KR101529160B1 (ko)	2015-06-16
RU2550270C2 (ru)	2015-05-10
EP2401300B1 (en)	2018-01-10
ES2665495T3 (es)	2018-04-26
US20120207746A1 (en)	2012-08-16
KR20120019429A (ko)	2012-03-06
US8974794B2 (en)	2015-03-10
DK2401300T3 (en)	2018-04-23
SG174161A1 (en)	2011-11-28
RU2011139083A (ru)	2013-04-10
HUE036920T2 (hu)	2018-08-28
CN104667271B (zh)	2018-01-05
PT2401300T (pt)	2018-04-17
US20130302314A1 (en)	2013-11-14

Publication	Publication Date	Title
BRPI1008317A2 (pt)	2018-03-13	"anticorpos anti-cemx capazes de se ligar a mige humana em linfócitos b"
CY2015058I2 (el)	2016-06-22	Αντισωματα προς ανθρωπινο προγραμματισμενου θανατου υποδοχεα pd-1
LTPA2018002I1 (lt)	2018-02-12	Didelio afiniškumo žmogaus antikūnai prieš žmogaus IK-4 receptorius
LT2975051T (lt)	2021-07-12	Lengvai išskiriami bispecifiniai antikūnai su natyvios formos imunoglobulinu
HUE037140T2 (hu)	2018-08-28	Humán GDF8-hoz kötõdõ ellenanyagok
DK2435568T3 (da)	2014-09-08	Samling af syntetiske antistoffer til behandling af sygdom
SMT201500011B (it)	2015-03-05	Anticorpi antichina che si legano a piu' chemochine cc
IL244801B (en)	2020-05-31	Human il-23 antigen binding proteins
EP3064512C0 (en)	2023-08-30	ANTIBODIES AGAINST CLDN6
IL217793A0 (en)	2012-03-29	Fully human antibodies to btla
FR2963449B1 (fr)	2013-01-25	Conversion d'un bus bifilaire en bus unifilaire
FR2926788B1 (fr)	2010-04-02	Fixation d'un turboreacteur multiflux a un aeronef
HRP20181645T1 (hr)	2018-12-14	Monoklonalna antitijela prema progastrinu i njihove upotrebe
BRPI0922505A2 (pt)	2016-07-05	proteínas de ligação a receptor cgrp humano
ZA201105918B (en)	2012-10-31	Fully human antibodies specific to cadm1
EP2207803A4 (en)	2010-11-24	Cd9-specific human antibodies
FI20075278A0 (fi)	2007-04-20	Uudet täysin ihmisperäiset anti-VAP-1 monoklonaaliset vasta-aineet
EP2125890A4 (en)	2010-04-07	ANTIBODIES AGAINST PHOSPHORYLATED IRAQ4
HRP20181973T1 (hr)	2019-01-25	Poboljšana anti humana fraktalkinska protutijela i njihova uporaba
FR2961784B1 (fr)	2012-08-10	Bicyclette pliable
EP2495319A4 (en)	2013-07-03	INTEGRIN-alpha8beta1-SPECIFIC MONOCLONAL ANTIBODY
FR2961107B1 (fr)	2012-07-27	Composition d'immunoglobulines humaines stabilisee
EP2565414A4 (en)	2016-04-27	EXHAUST
EP2543841A4 (en)	2014-07-23	EXHAUST
BRPI1010781A2 (pt)	2016-03-22	"análise multiplex de proteínas trangênicas empilhadas"

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