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BRPI1008023A2 - forma de dosagem sólida - Google Patents

forma de dosagem sólida

Info

Publication number
BRPI1008023A2
BRPI1008023A2 BRPI1008023A BRPI1008023A BRPI1008023A2 BR PI1008023 A2 BRPI1008023 A2 BR PI1008023A2 BR PI1008023 A BRPI1008023 A BR PI1008023A BR PI1008023 A BRPI1008023 A BR PI1008023A BR PI1008023 A2 BRPI1008023 A2 BR PI1008023A2
Authority
BR
Brazil
Prior art keywords
dosage form
solid dosage
solid
dosage
Prior art date
Application number
BRPI1008023A
Other languages
English (en)
Inventor
Colin J Meyer
Jiang Zhang
Original Assignee
Reata Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42335073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1008023(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Reata Pharmaceuticals Inc filed Critical Reata Pharmaceuticals Inc
Publication of BRPI1008023A2 publication Critical patent/BRPI1008023A2/pt
Publication of BRPI1008023B1 publication Critical patent/BRPI1008023B1/pt
Publication of BRPI1008023B8 publication Critical patent/BRPI1008023B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI1008023A 2009-02-13 2010-02-12 Forma de dosagem sólida BRPI1008023B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15260809P 2009-02-13 2009-02-13
PCT/US2010/024127 WO2010093944A2 (en) 2009-02-13 2010-02-12 Delayed release, oral dosage compositions that contain amorphous cddo-me

Publications (3)

Publication Number Publication Date
BRPI1008023A2 true BRPI1008023A2 (pt) 2016-03-15
BRPI1008023B1 BRPI1008023B1 (pt) 2019-12-31
BRPI1008023B8 BRPI1008023B8 (pt) 2023-04-11

Family

ID=42335073

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1008023A BRPI1008023B8 (pt) 2009-02-13 2010-02-12 Forma de dosagem sólida

Country Status (30)

Country Link
US (2) US8747901B2 (pt)
EP (2) EP3254675B1 (pt)
JP (1) JP5775464B2 (pt)
KR (2) KR20140016441A (pt)
CN (2) CN102387789A (pt)
AU (1) AU2010213594B2 (pt)
BR (1) BRPI1008023B8 (pt)
CA (1) CA2752048C (pt)
CO (1) CO6361904A2 (pt)
CY (2) CY1119595T1 (pt)
DK (2) DK2395979T3 (pt)
EA (1) EA023652B1 (pt)
ES (2) ES2646816T3 (pt)
HK (1) HK1220130A1 (pt)
HR (2) HRP20171639T1 (pt)
HU (2) HUE035013T2 (pt)
IL (1) IL214258A (pt)
LT (2) LT3254675T (pt)
MX (1) MX2011008344A (pt)
MY (1) MY173715A (pt)
NO (1) NO2395979T3 (pt)
NZ (1) NZ594488A (pt)
PL (2) PL2395979T3 (pt)
PT (2) PT2395979T (pt)
SG (1) SG173601A1 (pt)
SI (2) SI3254675T1 (pt)
SM (2) SMT201700527T1 (pt)
TR (1) TR201909743T4 (pt)
WO (1) WO2010093944A2 (pt)
ZA (1) ZA201105630B (pt)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326507B1 (en) 1998-06-19 2001-12-04 Trustees Of Dartmouth College Therapeutic compounds and methods of use
CN104739841B (zh) 2008-01-11 2018-06-01 里亚塔医药公司 合成三萜类化合物及用以治病之方法
BRPI0911105B1 (pt) 2008-04-18 2022-11-08 Reata Pharmaceuticals, Inc Compostos contendo um farmacóforo anti-inflamatório, composição farmacêutica, bem como seus usos
US8124799B2 (en) 2008-04-18 2012-02-28 Reata Pharmaceuticals, Inc. Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at C-17
CA2721666C (en) 2008-04-18 2017-05-23 Reata Pharmaceuticals, Inc. Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives
TWI442925B (zh) 2008-04-18 2014-07-01 Reata Pharmaceuticals Inc 抗氧化性發炎調節劑:c-環飽和之齊墩果酸衍生物
CA2731650A1 (en) 2008-07-22 2010-01-28 Tadashi Honda Monocyclic cyanoenones and methods of use thereof
JP5775464B2 (ja) 2009-02-13 2015-09-09 リアタ ファーマシューティカルズ,インク 非晶質cddo−meを含有する遅延放出性経口投薬組成物
MY163031A (en) 2010-04-12 2017-07-31 Reata Pharmaceuticals Inc Method of treating obesity using antioxidant inflammation modulators
ME02973B (me) 2010-12-17 2018-07-20 Reata Pharmaceuticals Inc Pirazolil i pirimidinil triciklični enoni kao antioksidantni modulatori inflamacije
UY33946A (es) 2011-03-11 2012-08-31 Reata Pharmaceuticals Inc Derivados de c4-monometil triterpenoides y sus métodos de uso
CN103156861B (zh) * 2011-12-08 2015-11-25 陈丽梅 齐敦果酸衍生物及其可药用盐在治疗糖尿病眼病中的应用
US9504679B2 (en) 2011-12-19 2016-11-29 Bjoern Colin Kahrs Pharmaceutical compositions comprising glitazones and Nrf2 activators
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
PT3444261T (pt) 2012-04-27 2021-03-12 Reata Pharmaceuticals Inc Derivados de 2,2-difluoropropionamida de metil bardoxolona, formas polimorfas e métodos de uso dos mesmos
US8981144B2 (en) 2012-05-08 2015-03-17 Trustees Of Dartmouth College Method for synthesizing 2-cyano-3,12-dioxoolean-1, 9(11)-dien-28-oic acid methyl ester and derivatives thereof
US8921419B2 (en) 2012-05-08 2014-12-30 Trustees Of Dartmouth College Triterpenoids and compositions containing the same
US9556222B2 (en) 2012-06-15 2017-01-31 Reata Pharmaceuticals, Inc. A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof
US9512094B2 (en) 2012-09-10 2016-12-06 Reata Pharmaceuticals, Inc. C17-heteroaryl derivatives of oleanolic acid and methods of use thereof
TWI630212B (zh) 2012-09-10 2018-07-21 瑞塔醫藥有限責任公司 丁香油素(oleanolic acid)之c17-烷二基與烯二基衍生物及其使用方法
US9278912B2 (en) 2012-09-10 2016-03-08 Reata Pharmaceuticals, Inc. C13-hydroxy derivatives of oleanolic acid and methods of use thereof
UY39092A (es) 2013-04-24 2021-03-26 Abbvie Inc Derivados de 2,2-difluoropropanamida y metil bardoxolona, formas polimórficas y métodos de uso
CA2921386A1 (en) 2013-08-23 2015-02-26 Reata Pharmaceuticals, Inc. Methods of treating and preventing renal disease using bardoxolone methyl or analogs thereof
EP3212195A4 (en) 2014-10-31 2018-06-06 The Regents of The University of California Compositions and methods for treating hiv-associated cognitive dysfunction
WO2016130927A1 (en) 2015-02-12 2016-08-18 Reata Pharmaceuticals, Inc. Imidazolyl tricyclic enones as antioxidant iflammation modulators
AU2016326704B2 (en) 2015-09-23 2021-01-28 Reata Pharmaceuticals, Inc. C4-modified oleanolic acid derivatives for inhibition of IL-17 and other uses
BR112019009256A2 (pt) 2016-11-08 2019-07-16 Reata Pharmaceuticals Inc métodos para tratar síndrome de alport usando bardoxolona metil ou análogos do mesmo
TWI831738B (zh) 2016-12-16 2024-02-11 美商瑞塔醫藥有限責任公司 用於抑制RORγ及其他用途的嘧啶三環烯酮衍生物
US11427533B2 (en) 2017-07-13 2022-08-30 Pliva Hrvatska D.O.O. Crystalline polymorphs of bardoxolone methyl
WO2019193488A1 (en) 2018-04-06 2019-10-10 Capsugel Belgium Nv Spray drying process for low aspect ratio particles comprising poly[(methyl methacrylate)-co-(methacrylic acid)]
CA3103726A1 (en) 2018-06-15 2019-12-19 Reata Pharmaceuticals, Inc. Pyrazole and imidazole compounds for inhibition of il-17 and rorgamma
WO2019246461A1 (en) 2018-06-20 2019-12-26 Reata Pharmaceuticals, Inc. Cysteine-dependent inverse agonists of nuclear receptors ror-gamma/ror-gamma-t and methods of treating diseases or disorders therewith
KR20210096162A (ko) 2018-11-27 2021-08-04 쿄와 기린 가부시키가이샤 의약 조성물
AU2020316351A1 (en) 2019-07-19 2022-02-17 Reata Pharmaceuticals, Inc. C17 polar-substituted heteroaromatic synthetic triterpenoids and methods of use thereof
CA3177913A1 (en) 2020-05-09 2021-11-18 Deborah FERGUSON Methods of treating covid-19 using bardoxolone methyl or analogs thereof
WO2022126129A1 (en) 2020-12-11 2022-06-16 Reata Pharmaceuticals, Inc. Synthetic triterpenoids for use in therapy
CN114558019A (zh) * 2022-03-26 2022-05-31 中国科学院昆明动物研究所 一种Rab13基因抑制剂及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326507B1 (en) 1998-06-19 2001-12-04 Trustees Of Dartmouth College Therapeutic compounds and methods of use
US7435755B2 (en) * 2000-11-28 2008-10-14 The Trustees Of Dartmouth College CDDO-compounds and combination therapies thereof
JP2008110962A (ja) * 2006-08-02 2008-05-15 Santen Pharmaceut Co Ltd Nrf2活性化物質を有効成分として含む角結膜障害の予防または治療剤
JP4315182B2 (ja) * 2006-10-30 2009-08-19 ミツミ電機株式会社 カメラモジュール
WO2008111497A1 (ja) * 2007-03-08 2008-09-18 Santen Pharmaceutical Co., Ltd. トリテルペノイドを有効成分として含有する酸化ストレスが関連する眼疾患の予防又は治療剤
US8088824B2 (en) * 2007-08-15 2012-01-03 Reata Pharmaceuticals Inc. Forms of CDDO methyl ester
CN104739841B (zh) * 2008-01-11 2018-06-01 里亚塔医药公司 合成三萜类化合物及用以治病之方法
JP5775464B2 (ja) 2009-02-13 2015-09-09 リアタ ファーマシューティカルズ,インク 非晶質cddo−meを含有する遅延放出性経口投薬組成物

Also Published As

Publication number Publication date
AU2010213594A1 (en) 2011-08-18
CN102387789A (zh) 2012-03-21
ZA201105630B (en) 2012-04-25
HRP20171639T1 (hr) 2017-12-15
BRPI1008023B8 (pt) 2023-04-11
HUE044005T2 (hu) 2019-09-30
SG173601A1 (en) 2011-09-29
WO2010093944A2 (en) 2010-08-19
US20140235711A1 (en) 2014-08-21
ES2646816T3 (es) 2017-12-18
KR20140016441A (ko) 2014-02-07
PL3254675T3 (pl) 2019-09-30
BRPI1008023B1 (pt) 2019-12-31
NO2395979T3 (pt) 2018-01-20
CO6361904A2 (es) 2012-01-20
SI3254675T1 (sl) 2019-08-30
EP2395979A2 (en) 2011-12-21
WO2010093944A3 (en) 2011-08-11
KR101483203B1 (ko) 2015-01-15
IL214258A (en) 2017-06-29
DK2395979T3 (da) 2017-11-27
JP5775464B2 (ja) 2015-09-09
EA023652B1 (ru) 2016-06-30
PT3254675T (pt) 2019-06-14
LT3254675T (lt) 2019-06-25
LT2395979T (lt) 2017-12-11
TR201909743T4 (tr) 2019-07-22
PL2395979T3 (pl) 2018-02-28
AU2010213594B2 (en) 2013-11-14
CY1122066T1 (el) 2020-11-25
HK1220130A1 (zh) 2017-04-28
SMT201900432T1 (it) 2019-09-09
JP2012518008A (ja) 2012-08-09
CA2752048A1 (en) 2010-08-19
HRP20191092T1 (hr) 2019-11-29
EP3254675B1 (en) 2019-05-15
HUE035013T2 (en) 2018-05-02
ES2731601T3 (es) 2019-11-18
US20120022156A1 (en) 2012-01-26
US8747901B2 (en) 2014-06-10
SMT201700527T1 (it) 2018-01-11
CA2752048C (en) 2014-11-25
EP3254675A1 (en) 2017-12-13
EA201190092A1 (ru) 2012-02-28
NZ594488A (en) 2013-10-25
SI2395979T1 (sl) 2017-12-29
CY1119595T1 (el) 2018-03-07
US9155721B2 (en) 2015-10-13
IL214258A0 (en) 2011-09-27
KR20110118721A (ko) 2011-10-31
CN105232471A (zh) 2016-01-13
DK3254675T3 (da) 2019-06-24
MY173715A (en) 2020-02-18
MX2011008344A (es) 2011-09-29
EP2395979B1 (en) 2017-08-23
PT2395979T (pt) 2017-11-16

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/02/2010, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved

Owner name: REATA PHARMACEUTICALS HOLDINGS, LLC (US)