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BRPI1005405A2 - dispositivo para determinar a cardiotoxidade de um composto químico, método para fabricação de dispositivo, método de determinação da cardiotoxidade de um composto químico e uso do dispositivo - Google Patents

dispositivo para determinar a cardiotoxidade de um composto químico, método para fabricação de dispositivo, método de determinação da cardiotoxidade de um composto químico e uso do dispositivo

Info

Publication number
BRPI1005405A2
BRPI1005405A2 BRPI1005405A BRPI1005405A BRPI1005405A2 BR PI1005405 A2 BRPI1005405 A2 BR PI1005405A2 BR PI1005405 A BRPI1005405 A BR PI1005405A BR PI1005405 A BRPI1005405 A BR PI1005405A BR PI1005405 A2 BRPI1005405 A2 BR PI1005405A2
Authority
BR
Brazil
Prior art keywords
cardiotoxicity
determining
chemical compound
manufacturing
manufacturing device
Prior art date
Application number
BRPI1005405A
Other languages
English (en)
Inventor
Anja Van De Stolpe
Ronald Dekker
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Publication of BRPI1005405A2 publication Critical patent/BRPI1005405A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5061—Muscle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography
    • C12N2535/10—Patterned coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BRPI1005405A 2009-02-09 2010-02-05 dispositivo para determinar a cardiotoxidade de um composto químico, método para fabricação de dispositivo, método de determinação da cardiotoxidade de um composto químico e uso do dispositivo BRPI1005405A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09152378A EP2218772A1 (en) 2009-02-09 2009-02-09 Cardiomyocytes-containing device and method for manufacturing the same
PCT/IB2010/050537 WO2010089718A1 (en) 2009-02-09 2010-02-05 Cardiomyocytes-containing device and method for manufacturing and using the same

Publications (1)

Publication Number Publication Date
BRPI1005405A2 true BRPI1005405A2 (pt) 2016-10-18

Family

ID=40561887

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1005405A BRPI1005405A2 (pt) 2009-02-09 2010-02-05 dispositivo para determinar a cardiotoxidade de um composto químico, método para fabricação de dispositivo, método de determinação da cardiotoxidade de um composto químico e uso do dispositivo

Country Status (6)

Country Link
US (2) US8506793B2 (pt)
EP (2) EP2218772A1 (pt)
CN (1) CN102333856B (pt)
BR (1) BRPI1005405A2 (pt)
RU (1) RU2524134C2 (pt)
WO (1) WO2010089718A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10209243B2 (en) * 2010-08-05 2019-02-19 Koninklijke Philips N.V. Cardiomyocyte containing device, manufacturing method and measuring method
WO2012036224A1 (ja) * 2010-09-14 2012-03-22 学校法人 東京女子医科大学 細胞シート積層化物の製造方法、それより得られる血管網を有する細胞シート積層化物及びその利用方法
US10711248B2 (en) * 2013-12-18 2020-07-14 Cytoo Device and method for standardizing myoblast differentiation into myotubes
CN104225681B (zh) * 2014-09-19 2016-03-02 浙江大学 一种组织工程骨及其制备方法
FR3046299B1 (fr) * 2015-12-23 2017-12-22 Commissariat Energie Atomique Procede de realisation d'une cavite fermee comportant un clapet protegeant la cavite lors de sa fermeture
LU92948B1 (en) * 2016-01-15 2017-09-25 Fachhochschule Aachen CellDrum electrode arrangement for measuring mechanical stress
US12411128B2 (en) * 2017-06-26 2025-09-09 The Regents Of The University Of California Methods and apparatuses for prediction of mechanism of activity of compounds
CN107907485B (zh) * 2017-11-09 2020-03-31 东南大学 一种基于结构色水凝胶的心脏芯片及其应用
US11932844B2 (en) 2018-10-09 2024-03-19 Hewlett-Packard Development Company, L.P. Flat-form imaging for microscopic objects
CN113908333A (zh) * 2020-07-10 2022-01-11 国家纳米科学中心 柔性电传导芯片、其制备方法及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1377738A1 (ru) * 1985-11-21 1988-02-28 Институт Проблем Механики Ан Ссср Способ определени сократимости кардиомиоцита
US5850026A (en) 1996-07-03 1998-12-15 Cargill, Incorporated Canola oil having increased oleic acid and decreased linolenic acid content
FR2779525B1 (fr) * 1998-06-08 2000-10-13 Claude Hanni Appareil de mesure de l'activite electrophysiologique d'un amas de cellules
EP1423501A4 (en) * 2001-08-06 2008-08-06 Univ Vanderbilt DEVICE AND METHOD FOR MEASURING THE RESPONSE OF AT LEAST ONE CELL TO A MEDIUM
US7611852B2 (en) 2002-07-26 2009-11-03 Wisconsin Alumni Research Foundation Functional cardiomyocytes from human embryonic stem cells
US6878643B2 (en) 2002-12-18 2005-04-12 The Regents Of The University Of California Electronic unit integrated into a flexible polymer body
US10551371B2 (en) * 2003-11-10 2020-02-04 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function
US7337012B2 (en) 2003-04-30 2008-02-26 Lawrence Livermore National Security, Llc Stretchable polymer-based electronic device
CA2560334A1 (en) 2004-04-07 2005-10-20 Axiogenesis Ag Non-invasive, in vitro functional tissue assay systems
CN101213142A (zh) * 2005-06-30 2008-07-02 皇家飞利浦电子股份有限公司 制造mems元件的方法
JP2009516388A (ja) * 2005-11-18 2009-04-16 レプリソールス テクノロジーズ アーベー 多層構造の形成方法
US20100196432A1 (en) 2006-10-10 2010-08-05 Feinberg Adam W Biopolymer structures
CN101711276B (zh) * 2007-06-08 2014-05-07 国立大学法人东京医科齿科大学 模型细胞芯片，利用模型细胞芯片的药效评价装置以及药效评价方法
CN101082523B (zh) * 2007-06-27 2010-10-06 中国科学院上海微系统与信息技术研究所 一种柔性温度传感器的制作方法

Also Published As

Publication number Publication date
RU2011137133A (ru) 2013-03-20
US20140065657A1 (en) 2014-03-06
US20120094323A1 (en) 2012-04-19
EP2393913A1 (en) 2011-12-14
CN102333856B (zh) 2014-06-04
WO2010089718A1 (en) 2010-08-12
US8506793B2 (en) 2013-08-13
CN102333856A (zh) 2012-01-25
RU2524134C2 (ru) 2014-07-27
EP2218772A1 (en) 2010-08-18

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]