BRPI0922920A2 - formas cristalinas de um composto de 3-carboxipropil-aminotetralina - Google Patents

formas cristalinas de um composto de 3-carboxipropil-aminotetralina

Info

Publication number: BRPI0922920A2
Authority: BR; Brazil
Prior art keywords: carboxypropyl; crystalline forms; aminotetraline; compound; aminotetraline compound
Prior art date: 2008-12-10

Application number

BRPI0922920A

Other languages

English (en)

Inventor

Rapta Miroslav

Dalziel Sean

Original Assignee

Theravance Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-12-10

Filing date

2009-12-09

Publication date

2019-09-24

2009-12-09 Application filed by Theravance Inc filed Critical Theravance Inc

2019-09-24 Publication of BRPI0922920A2 publication Critical patent/BRPI0922920A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Nutrition Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BRPI0922920A 2008-12-10 2009-12-09 formas cristalinas de um composto de 3-carboxipropil-aminotetralina BRPI0922920A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12125408P	2008-12-10	2008-12-10
PCT/US2009/067271 WO2010068649A1 (en)	2008-12-10	2009-12-09	Crystalline forms of a 3-carboxypropyl-aminotetralin compound

Publications (1)

Publication Number	Publication Date
BRPI0922920A2 true BRPI0922920A2 (pt)	2019-09-24

Family

ID=42122774

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0922920A BRPI0922920A2 (pt)	2008-12-10	2009-12-09	formas cristalinas de um composto de 3-carboxipropil-aminotetralina

Country Status (21)

Country	Link
US (4)	US8101794B2 (pt)
EP (1)	EP2376427B1 (pt)
JP (1)	JP5650657B2 (pt)
KR (1)	KR101685187B1 (pt)
CN (1)	CN102245564B (pt)
AR (1)	AR074592A1 (pt)
AU (1)	AU2009324709B2 (pt)
BR (1)	BRPI0922920A2 (pt)
CA (1)	CA2745441C (pt)
CL (1)	CL2011001391A1 (pt)
CO (1)	CO6390054A2 (pt)
ES (1)	ES2645087T3 (pt)
IL (1)	IL213093A0 (pt)
MX (1)	MX2011006209A (pt)
MY (1)	MY179041A (pt)
NZ (1)	NZ593377A (pt)
RU (1)	RU2512390C2 (pt)
SG (1)	SG172016A1 (pt)
TW (1)	TWI449685B (pt)
WO (1)	WO2010068649A1 (pt)
ZA (1)	ZA201104319B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009076399A2 (en)	2007-12-11	2009-06-18	Theravance, Inc.	Aminotetralin compounds as mu opioid receptor antagonists
NZ586048A (en)	2007-12-11	2012-06-29	Theravance Inc	3 -carboxypropyl-aminotetralin derivatives as mu opioid receptor antagonists
AU2010295464B2 (en) *	2009-09-18	2015-11-26	Merck Sharp & Dohme Corp.	Use of opioid receptor antagonist for gastrointestinal tract disorders
CA2846200A1 (en) *	2011-09-30	2013-04-04	Theravance, Inc.	Crystalline forms of a 3-[2-methanesulfonyl-1-(4-trifluoromethyl-phenoxy)ethyl]pyrrolidine compound

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6498196B1 (en)	1998-12-22	2002-12-24	Edward Roberts	Compounds useful in pain management
US6844368B1 (en)	1998-12-22	2005-01-18	Edward Roberts	Compounds useful in pain management
US6231594B1 (en)	1999-08-11	2001-05-15	Radiant Medical, Inc.	Method of controlling body temperature while reducing shivering
CA2486092A1 (en) *	2002-05-17	2003-11-27	Janssen Pharmaceutica N.V.	Aminotetralin-derived urea modulators of vanilloid vr1 receptor
CA2521420A1 (en) *	2003-04-08	2004-10-28	Progenics Pharmaceuticals, Inc.	Combination therapy for constipation comprising a laxative and a peripheral opioid antagonist
SE0301794D0 (sv) *	2003-06-19	2003-06-19	Astrazeneca Ab	New use III
EA201100544A1 (ru)	2006-11-07	2012-01-30	Нектар Терапьютикс	Применение комбинации опиоидного агониста и конъюгата полимер-опиоидный антагонист для изготовления лекарственного средства для лечения и предупреждения боли
EP1997493A1 (en) *	2007-05-28	2008-12-03	Laboratorios del Dr. Esteve S.A.	Combination of a 5-HT7 receptor ligand and an opioid receptor ligand
WO2009076399A2 (en)	2007-12-11	2009-06-18	Theravance, Inc.	Aminotetralin compounds as mu opioid receptor antagonists
NZ586048A (en)	2007-12-11	2012-06-29	Theravance Inc	3 -carboxypropyl-aminotetralin derivatives as mu opioid receptor antagonists
US8153686B2 (en)	2008-04-01	2012-04-10	Theravance, Inc.	Amino- and amido-aminotetralin derivatives and related compounds as mu opioid receptor antagonists

2009
- 2009-12-09 TW TW098142108A patent/TWI449685B/zh not_active IP Right Cessation
- 2009-12-09 SG SG2011041605A patent/SG172016A1/en unknown
- 2009-12-09 EP EP09793383.2A patent/EP2376427B1/en not_active Not-in-force
- 2009-12-09 NZ NZ593377A patent/NZ593377A/xx not_active IP Right Cessation
- 2009-12-09 KR KR1020117015637A patent/KR101685187B1/ko not_active Expired - Fee Related
- 2009-12-09 CN CN200980149818.7A patent/CN102245564B/zh not_active Expired - Fee Related
- 2009-12-09 WO PCT/US2009/067271 patent/WO2010068649A1/en not_active Ceased
- 2009-12-09 MX MX2011006209A patent/MX2011006209A/es active IP Right Grant
- 2009-12-09 ES ES09793383.2T patent/ES2645087T3/es active Active
- 2009-12-09 CA CA2745441A patent/CA2745441C/en active Active
- 2009-12-09 RU RU2011128393/04A patent/RU2512390C2/ru active
- 2009-12-09 JP JP2011540855A patent/JP5650657B2/ja not_active Expired - Fee Related
- 2009-12-09 US US12/633,944 patent/US8101794B2/en not_active Expired - Fee Related
- 2009-12-09 AU AU2009324709A patent/AU2009324709B2/en not_active Ceased
- 2009-12-09 BR BRPI0922920A patent/BRPI0922920A2/pt not_active IP Right Cessation
- 2009-12-09 MY MYPI2011002349A patent/MY179041A/en unknown
- 2009-12-10 AR ARP090104803A patent/AR074592A1/es unknown
2011
- 2011-05-24 IL IL213093A patent/IL213093A0/en active IP Right Grant
- 2011-06-08 CL CL2011001391A patent/CL2011001391A1/es unknown
- 2011-06-08 CO CO11070977A patent/CO6390054A2/es active IP Right Grant
- 2011-06-09 ZA ZA2011/04319A patent/ZA201104319B/en unknown
- 2011-12-19 US US13/330,358 patent/US8324236B2/en not_active Expired - Fee Related
2012
- 2012-10-29 US US13/663,083 patent/US8486958B2/en not_active Expired - Fee Related
2013
- 2013-06-17 US US13/919,260 patent/US8969367B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
RU2512390C2 (ru)	2014-04-10
US20100144881A1 (en)	2010-06-10
AU2009324709A1 (en)	2011-06-30
MX2011006209A (es)	2011-07-12
SG172016A1 (en)	2011-07-28
EP2376427B1 (en)	2017-08-02
CN102245564B (zh)	2015-04-01
JP2012511580A (ja)	2012-05-24
US8969367B2 (en)	2015-03-03
US8324236B2 (en)	2012-12-04
US8101794B2 (en)	2012-01-24
US20130065916A1 (en)	2013-03-14
CL2011001391A1 (es)	2011-11-11
NZ593377A (en)	2013-07-26
ES2645087T3 (es)	2017-12-04
WO2010068649A1 (en)	2010-06-17
US20120088834A1 (en)	2012-04-12
KR20110093938A (ko)	2011-08-18
JP5650657B2 (ja)	2015-01-07
US20130345466A1 (en)	2013-12-26
TW201026646A (en)	2010-07-16
CN102245564A (zh)	2011-11-16
US8486958B2 (en)	2013-07-16
EP2376427A1 (en)	2011-10-19
CA2745441A1 (en)	2010-06-17
ZA201104319B (en)	2012-03-28
IL213093A0 (en)	2011-07-31
TWI449685B (zh)	2014-08-21
KR101685187B1 (ko)	2016-12-09
AU2009324709B2 (en)	2015-07-16
CA2745441C (en)	2017-10-17
CO6390054A2 (es)	2012-02-29
RU2011128393A (ru)	2013-01-20
AR074592A1 (es)	2011-01-26
MY179041A (en)	2020-10-26

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BRPI0922464A2 (pt)	2015-08-11	Combinações de compostos ativos
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EP2423203A4 (en)	2012-10-31	CRYSTAL OF A BENZOXAZINONE COMPOUND
BRPI0923592A2 (pt)	2016-01-26	composto

Legal Events

Date	Code	Title	Description
2019-10-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2019-12-10	B25A	Requested transfer of rights approved	Owner name: THERAVANCE BIOPHARMA RANDD IP, LLC (US)
2020-01-21	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.