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BRPI0922800A2 - anticorpos c-met - Google Patents

anticorpos c-met

Info

Publication number
BRPI0922800A2
BRPI0922800A2 BRPI0922800A BRPI0922800A BRPI0922800A2 BR PI0922800 A2 BRPI0922800 A2 BR PI0922800A2 BR PI0922800 A BRPI0922800 A BR PI0922800A BR PI0922800 A BRPI0922800 A BR PI0922800A BR PI0922800 A2 BRPI0922800 A2 BR PI0922800A2
Authority
BR
Brazil
Prior art keywords
met antibodies
antibodies
met
Prior art date
Application number
BRPI0922800A
Other languages
English (en)
Inventor
Jirong Lu
Julian Davies
Ling Liu
Mark Andrew Wortinger
Peter Edward Vaillancourt
Wei Zeng
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BRPI0922800A2 publication Critical patent/BRPI0922800A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0922800A 2008-11-21 2009-11-18 anticorpos c-met BRPI0922800A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11682508P 2008-11-21 2008-11-21
US21990309P 2009-06-24 2009-06-24
PCT/US2009/064881 WO2010059654A1 (en) 2008-11-21 2009-11-18 c-MET ANTIBODIES

Publications (1)

Publication Number Publication Date
BRPI0922800A2 true BRPI0922800A2 (pt) 2015-12-22

Family

ID=41435259

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922800A BRPI0922800A2 (pt) 2008-11-21 2009-11-18 anticorpos c-met

Country Status (27)

Country Link
US (2) US8217148B2 (pt)
EP (2) EP2358755B1 (pt)
JP (1) JP5688027B2 (pt)
KR (1) KR101334450B1 (pt)
CN (1) CN102216333B (pt)
AR (1) AR074360A1 (pt)
AU (1) AU2009316742B2 (pt)
BR (1) BRPI0922800A2 (pt)
CA (1) CA2743508C (pt)
CY (1) CY1116886T1 (pt)
DK (1) DK2358755T3 (pt)
EA (1) EA020398B1 (pt)
ES (2) ES2549760T3 (pt)
HR (1) HRP20151019T1 (pt)
HU (1) HUE026058T2 (pt)
IL (1) IL212633A (pt)
JO (1) JO3097B1 (pt)
MX (1) MX2011005400A (pt)
NZ (1) NZ592215A (pt)
PA (1) PA8849001A1 (pt)
PL (1) PL2358755T3 (pt)
PT (1) PT2358755E (pt)
SI (1) SI2358755T1 (pt)
TR (1) TR201802841T4 (pt)
TW (1) TWI477284B (pt)
WO (1) WO2010059654A1 (pt)
ZA (1) ZA201103586B (pt)

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Also Published As

Publication number Publication date
MX2011005400A (es) 2011-06-20
JP5688027B2 (ja) 2015-03-25
HRP20151019T1 (hr) 2015-10-23
CA2743508A1 (en) 2010-05-27
US20100129369A1 (en) 2010-05-27
KR101334450B1 (ko) 2013-12-02
PA8849001A1 (es) 2010-06-28
US20120263723A1 (en) 2012-10-18
US8217148B2 (en) 2012-07-10
CY1116886T1 (el) 2017-04-05
PT2358755E (pt) 2015-11-12
EP2963058A1 (en) 2016-01-06
ZA201103586B (en) 2013-10-30
CA2743508C (en) 2016-07-19
EA201170716A1 (ru) 2011-12-30
JO3097B1 (ar) 2017-03-15
TR201802841T4 (tr) 2018-03-21
HK1158229A1 (en) 2012-07-13
TW201023885A (en) 2010-07-01
IL212633A (en) 2015-03-31
EP2358755A1 (en) 2011-08-24
WO2010059654A1 (en) 2010-05-27
DK2358755T3 (en) 2015-11-16
HUE026058T2 (en) 2016-05-30
EP2963058B1 (en) 2018-02-21
PL2358755T3 (pl) 2016-01-29
EP2358755B1 (en) 2015-09-02
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AU2009316742B2 (en) 2012-06-07
AR074360A1 (es) 2011-01-12
EA020398B1 (ru) 2014-10-30
CN102216333A (zh) 2011-10-12
AU2009316742A1 (en) 2010-05-27
ES2663825T3 (es) 2018-04-17
IL212633A0 (en) 2011-07-31
ES2549760T3 (es) 2015-11-02
JP2012509881A (ja) 2012-04-26
KR20110074612A (ko) 2011-06-30
CN102216333B (zh) 2014-05-21
US8398974B2 (en) 2013-03-19
SI2358755T1 (sl) 2015-10-30

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