BRPI0922566A2 - polimorfo cristalino, composição farmacêutica, composto, e, métodos para preparar um composto, e para tratar uma doença. - Google Patents

polimorfo cristalino, composição farmacêutica, composto, e, métodos para preparar um composto, e para tratar uma doença.

Info

Publication number: BRPI0922566A2
Authority: BR; Brazil
Prior art keywords: compound; disease; treating; preparing; methods
Prior art date: 2008-12-17

Application number

BRPI0922566A

Other languages

English (en)

Inventor

A Norton Beth

Wheeler Conrad

Todd Dan

Chen Pingyun

Original Assignee

Anacor Pharmaceuticals Inc

Glaxosmithkline Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-12-17

Filing date

2009-12-17

Publication date

2017-03-28

2009-12-17 Application filed by Anacor Pharmaceuticals Inc, Glaxosmithkline Llc filed Critical Anacor Pharmaceuticals Inc

2017-03-28 Publication of BRPI0922566A2 publication Critical patent/BRPI0922566A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BRPI0922566A 2008-12-17 2009-12-17 polimorfo cristalino, composição farmacêutica, composto, e, métodos para preparar um composto, e para tratar uma doença. BRPI0922566A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US13849008P	2008-12-17	2008-12-17
PCT/US2009/068609 WO2010080558A1 (en)	2008-12-17	2009-12-17	Polymorphs of (s)-3-aminomethyl-7-(3-hydroxy-propoxy)-3h-benzo[c][1,2] oxaborol-1-ol

Publications (1)

Publication Number	Publication Date
BRPI0922566A2 true BRPI0922566A2 (pt)	2017-03-28

Family

ID=42316734

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0922566A BRPI0922566A2 (pt)	2008-12-17	2009-12-17	polimorfo cristalino, composição farmacêutica, composto, e, métodos para preparar um composto, e para tratar uma doença.

Country Status (18)

Country	Link
US (1)	US8461364B2 (pt)
EP (1)	EP2378886A4 (pt)
JP (1)	JP2012512262A (pt)
KR (1)	KR20110111407A (pt)
CN (1)	CN102256494A (pt)
AU (1)	AU2009335744A1 (pt)
BR (1)	BRPI0922566A2 (pt)
CA (1)	CA2744231A1 (pt)
CO (1)	CO6390029A2 (pt)
CR (1)	CR20110357A (pt)
DO (1)	DOP2011000183A (pt)
EA (1)	EA201190034A1 (pt)
IL (1)	IL213060A0 (pt)
MA (1)	MA32977B1 (pt)
MX (1)	MX2011006334A (pt)
PE (1)	PE20120052A1 (pt)
SG (1)	SG172040A1 (pt)
WO (1)	WO2010080558A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2009526751A (ja)	2005-12-30	2009-07-23	アナコールファーマシューティカルズ，インコーポレイテッド	ホウ素含有小分子
RU2508113C2 (ru)	2006-02-16	2014-02-27	Анакор Фармасьютикалз, Инк.	Борсодержащие малые молекулы в качестве противовоспалительных средств
US8716478B2 (en)	2010-01-27	2014-05-06	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
SG187757A1 (en) *	2010-08-10	2013-03-28	Rempex Pharmaceuticals Inc	Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN108610356B (zh)	2010-09-07	2021-02-26	阿纳科制药公司	苯并氧杂硼杂环戊二烯衍生物用于治疗细菌感染
CA2858799A1 (en)	2011-12-22	2013-06-27	Micurx Pharmaceuticals, Inc.	Tricyclic boron compounds for antimicrobial therapy
US10070649B2 (en)	2013-01-30	2018-09-11	Agrofresh Inc.	Volatile applications against pathogens
US8669207B1 (en)	2013-01-30	2014-03-11	Dow Agrosciences, Llc.	Compounds and compositions
US9585396B2 (en)	2013-01-30	2017-03-07	Agrofresh Inc.	Volatile applications against pathogens
NZ710723A (en)	2013-01-30	2019-12-20	Agrofresh Inc	Use of benzoxaboroles as volatile antimicrobial agents on meats, plants, or plant parts
US11039617B2 (en)	2013-01-30	2021-06-22	Agrofresh Inc.	Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
WO2014121124A1 (en)	2013-02-01	2014-08-07	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules as antiprotozoal agents
NZ716350A (en)	2013-08-09	2022-12-23	Glaxosmithkline Ip No 2 Ltd	Tricyclic benzoxaborole compounds and uses thereof
WO2016001834A1 (en)	2014-07-01	2016-01-07	Daiichi Sankyo Company, Limited	Tricyclic benzoxaboroles as antibacterial agents
MA41494B1 (fr)	2015-02-12	2020-10-28	Glaxosmithkline Ip No 2 Ltd	Composés benzoxaborole substitués en position 4 et utilisations associées
TW201735792A (zh)	2016-03-07	2017-10-16	農業保鮮股份有限公司	使用苯并氧雜硼雜環戊烯化合物和防腐氣體作為作物的抗微生物劑之協同方法
US10961261B2 (en)	2017-03-01	2021-03-30	Anacor Pharmaceuticals, Inc.	Oxaborole analogs and uses thereof
US20230340530A1 (en)	2020-08-31	2023-10-26	Pfizer Inc.	Methods of Protecting RNA
KR20230121863A (ko)	2020-12-17	2023-08-21	아이덱스 래보러토리즈, 인코포레이티드	로키산 홍반열 검출 및 치료
WO2023246842A1 (en)	2022-06-23	2023-12-28	Shanghai Micurx Pharmaceutical Co., Ltd.	Prodrugs of boron compounds and their use in treating bacterial infections

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2260336A (en)	1939-10-16	1941-10-28	Dow Chemical Co	Method of preparation of organic borates
GB1396904A (en)	1972-08-11	1975-06-11	Ici Ltd	Method for the control of micro-organisms
US4766113A (en)	1975-10-24	1988-08-23	Chapman Chemical Company	Antimicrobial compositions and methods of using same
US4602011A (en)	1975-10-24	1986-07-22	Chapman Chemical Company	Antimicrobial compositions and methods of using same
US4716035A (en)	1985-05-24	1987-12-29	The Procter & Gamble Company	Oral compositions and methods for treating gingivitis
US5962498A (en)	1986-06-11	1999-10-05	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
US4894220A (en)	1987-01-30	1990-01-16	Colgate-Palmolive Company	Antibacterial antiplaque oral composition
SG47101A1 (en) *	1992-07-31	1998-03-20	Us Bioscience	Crystalline amifostine compositions and methods for the preparation and use of same
US5348948A (en)	1993-05-07	1994-09-20	American Cyanamid Company	2,2-diaryl-1-(oxa and thia)-2a-azonia-2-borataacenaphthene fungicidal
US5348947A (en)	1993-05-07	1994-09-20	American Cyanamid Company	Diarylboron ester and thioester fungicidal agents
US5594151A (en)	1994-01-28	1997-01-14	Prolinx, Inc.	Phenylboronic acid complexing reagents derived from aminosalicylic acid
GB9411587D0 (en)	1994-06-09	1994-08-03	Zeneca Ltd	Compound, composition and use
US6083903A (en)	1994-10-28	2000-07-04	Leukosite, Inc.	Boronic ester and acid compounds, synthesis and uses
GB9604926D0 (en)	1996-03-08	1996-05-08	Sandoz Ltd	Organic compounds
CA2258728C (en)	1996-06-19	2011-09-27	Rhone Poulenc Rorer Limited	Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase
US5831046A (en)	1996-08-05	1998-11-03	Prolinx, Incorporated	Boronic acid-contaning nucleic acid monomers
WO1998012206A1 (en)	1996-09-19	1998-03-26	The Board Of Trustees Of Leland Stanford Jr. University	Dna adenine methyltransferases and uses thereof
DE19829947A1 (de)	1998-07-04	2000-01-05	Bayer Ag	Elektrolumineszierende Anordnungen mit Bor-Chelaten
WO2000044387A1 (fr)	1999-01-29	2000-08-03	Nitto Kasei Co., Ltd.	Composes organobores presentant une activite de coccidiostats
CA2373279A1 (en)	1999-05-25	2000-12-14	The Penn State Research Foundation	Dna methyltransferase inhibitors
US6306628B1 (en)	1999-08-25	2001-10-23	Ambergen, Incorporated	Methods for the detection, analysis and isolation of Nascent proteins
WO2001025226A1 (en)	1999-10-05	2001-04-12	Bethesda Pharmaceuticals, Inc.	Dithiolane derivatives
WO2002006316A2 (en)	2000-07-14	2002-01-24	Zycos, Inc.	Alpha-msh related compounds and methods of use
EP1339725B1 (en)	2000-11-30	2006-11-22	The Penn State Research Foundation	Dna methyl transferase inhibitors
DE10110051C2 (de)	2001-03-02	2003-07-03	Clariant Gmbh	Verfahren zur Herstellung von Boron- und Borinsäuren
GB0117645D0 (en)	2001-07-19	2001-09-12	Isis Innovation	Therapeutic stratergies for prevention and treatment of alzheimers disease
DE10143979A1 (de)	2001-09-07	2003-03-27	Clariant Gmbh	Verfahren zur Herstellung von Bisallylboranen und nicht-aromatischen Boronsäuren
EP1444981A1 (en)	2001-10-11	2004-08-11	Katsuhiko Mikoshiba	Intracellular calcium concentration increase inhibitors
CA2473238A1 (en)	2002-01-10	2003-07-24	The Penn State Research Foundation	Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids
US7390806B2 (en)	2002-12-18	2008-06-24	Anacor Pharmaceuticals, Inc.	Antibiotics containing borinic acid complexes and methods of use
EP1581500A4 (en)	2002-12-18	2008-03-05	Anacor Pharmaceuticals Inc	ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE
WO2005000200A2 (en)	2003-05-09	2005-01-06	Sugen, Inc.	Novel kinases
RU2006101228A (ru)	2003-06-16	2006-07-27	Анакор Фармасьютикалз, Инк. (Us)	Гидролитически устойчивые борсодержащие терапевтические агенты и способы их применения
WO2005112970A2 (en)	2004-05-12	2005-12-01	The Brigham And Women's Hospital, Inc.	Use of gelsolin to treat infections
WO2006062731A1 (en)	2004-11-19	2006-06-15	University Of North Texas Health Science Center At Fort Worth	Phenanthroline and derivatives thereof used to lower intraocular pressure in an affected eye
GB0501944D0 (en)	2005-01-31	2005-03-09	Univ Cambridge Tech	Compounds for use in chemical detection and/or quantitation
PT3424932T (pt)	2005-02-16	2021-05-19	Anacor Pharmaceuticals Inc	Boronoftalidas para utilização terapêutica
TW200722087A (en)	2005-03-30	2007-06-16	Astion Dev As	Treatment of dermatological diseases and pruritus
US20080234229A1 (en)	2005-08-18	2008-09-25	Auspex Pharmaceuticals, Inc.	Novel Therapeutic Agents for the Treatment of Cancer, Metabolic Diseases and Skin Disorders
JP2009526751A (ja)	2005-12-30	2009-07-23	アナコールファーマシューティカルズ，インコーポレイテッド	ホウ素含有小分子
RU2508113C2 (ru)	2006-02-16	2014-02-27	Анакор Фармасьютикалз, Инк.	Борсодержащие малые молекулы в качестве противовоспалительных средств
EP2044091A4 (en)	2006-06-12	2010-08-04	Anacor Pharmaceuticals Inc	COMPOUNDS FOR THE TREATMENT OF PARODONTAL DISEASE
US20070286822A1 (en)	2006-06-12	2007-12-13	Anacor Pharmaceuticals Inc.	Compounds for the Treatment of Periodontal Disease
JO3396B1 (ar) *	2007-06-20	2019-10-20	Anacor Pharmaceuticals Inc	جزيئات صغيرة تحتوي على البورون
KR100895300B1 (ko)	2007-07-20	2009-05-07	한국전자통신연구원	생체신호 측정의복과 생체신호 처리시스템
WO2009111676A2 (en)	2008-03-06	2009-09-11	Anacor Pharmaceuticals, Inc	Boron-containing small molecules as anti-inflammatory agents
WO2009140309A2 (en)	2008-05-12	2009-11-19	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
WO2010028005A1 (en)	2008-09-04	2010-03-11	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
US9493489B2 (en)	2008-10-15	2016-11-15	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules as anti-protozoal agents
WO2010045505A1 (en)	2008-10-15	2010-04-22	Anacor Pharmaceuticals, Inc	Boron-containing small molecules as anti-protozoal agents

2009
- 2009-12-17 PE PE2011001246A patent/PE20120052A1/es not_active Application Discontinuation
- 2009-12-17 EA EA201190034A patent/EA201190034A1/ru unknown
- 2009-12-17 SG SG2011041894A patent/SG172040A1/en unknown
- 2009-12-17 CN CN2009801506662A patent/CN102256494A/zh active Pending
- 2009-12-17 JP JP2011542458A patent/JP2012512262A/ja active Pending
- 2009-12-17 MA MA34028A patent/MA32977B1/fr unknown
- 2009-12-17 BR BRPI0922566A patent/BRPI0922566A2/pt not_active IP Right Cessation
- 2009-12-17 WO PCT/US2009/068609 patent/WO2010080558A1/en not_active Ceased
- 2009-12-17 CA CA2744231A patent/CA2744231A1/en not_active Abandoned
- 2009-12-17 AU AU2009335744A patent/AU2009335744A1/en not_active Abandoned
- 2009-12-17 MX MX2011006334A patent/MX2011006334A/es not_active Application Discontinuation
- 2009-12-17 KR KR1020117016565A patent/KR20110111407A/ko not_active Withdrawn
- 2009-12-17 US US12/641,318 patent/US8461364B2/en not_active Expired - Fee Related
- 2009-12-17 EP EP09837955A patent/EP2378886A4/en not_active Withdrawn
2011
- 2011-05-23 IL IL213060A patent/IL213060A0/en unknown
- 2011-06-09 CO CO11071901A patent/CO6390029A2/es not_active Application Discontinuation
- 2011-06-13 DO DO2011000183A patent/DOP2011000183A/es unknown
- 2011-06-23 CR CR20110357A patent/CR20110357A/es unknown

Also Published As

Publication number	Publication date
WO2010080558A1 (en)	2010-07-15
CN102256494A (zh)	2011-11-23
CO6390029A2 (es)	2012-02-29
US8461364B2 (en)	2013-06-11
US20110152217A1 (en)	2011-06-23
MX2011006334A (es)	2011-09-22
AU2009335744A1 (en)	2010-07-15
EP2378886A4 (en)	2012-08-29
PE20120052A1 (es)	2012-02-13
MA32977B1 (fr)	2012-01-02
EA201190034A1 (ru)	2012-02-28
JP2012512262A (ja)	2012-05-31
SG172040A1 (en)	2011-07-28
IL213060A0 (en)	2011-07-31
EP2378886A1 (en)	2011-10-26
DOP2011000183A (es)	2011-07-15
KR20110111407A (ko)	2011-10-11
CA2744231A1 (en)	2010-07-15
CR20110357A (es)	2011-11-11

Publication	Publication Date	Title
BRPI0922566A2 (pt)	2017-03-28	polimorfo cristalino, composição farmacêutica, composto, e, métodos para preparar um composto, e para tratar uma doença.
BRPI0909691A2 (pt)	2015-08-04	Composto, método para preparar um composto, e, composição farmacêutica
BRPI0905717A2 (pt)	2015-07-14	Composição farmacêutica, processo para preparar uma composição farmacêutica e forma de dosagem farmacêutica
BRPI0914918A2 (pt)	2015-10-20	forma de dosagem farmacêutica, e, método para preparar uma forma de dosagem sólida.
BRPI0908092A2 (pt)	2015-08-25	Edulcorante, método para preparar uma composição edulcorante, e, composição edulcorante
BRPI0916689A2 (pt)	2015-11-17	composição farmacêutica estabilizada, preparação sólida, e, métodos para estabilizar uma composição farmacêutica, e para estabilizar uma preparação sólida.
BRPI0915382A2 (pt)	2017-06-27	composto, composição farmacêutica, e, método para tratar uma doença ou um distúrbio.
BRPI1011764A2 (pt)	2016-03-29	composição farmacêutica, e, método para preparar uma composição farmacêutica
BRPI0912384A2 (pt)	2015-10-13	composição, e, método para preparar uma composição
BRPI0910734A2 (pt)	2015-09-29	composto, composição farmacêutica, e, processo para preparar um composto ou um sal farmaceuticamente aceitável do mesmo.
BRPI0817423A2 (pt)	2015-06-16	Processos para a preparação de um composto, para a preparação de uma formulação farmacêutica, e para a preparação de um intermediário de um composto, e, composto
BRPI0819218A2 (pt)	2015-05-05	Métodos, estojos e composições para administração de compostos farmacêuticos
BRPI0912539A2 (pt)	2015-10-13	composto, composição farmacêutica , método para tratar uma doença, e, uso do composto.
BR112012004333A2 (pt)	2015-09-08	composto, composição farmacêutica, e, método para o tratamento ou a prevenção de uma doença ou um distúrbio.
BRPI0917196A2 (pt)	2015-11-10	método para a preparação de um complexo, e, forma cristalina de um composto.
BRPI0818533A2 (pt)	2017-06-06	composto, composição farmacêutica, e, processo para a preparação de um composto
BRPI0807756A2 (pt)	2014-06-17	Método para produzir um l-aminoácido.
BRPI1016132A2 (pt)	2016-04-19	composição, formulação farmacêutica, método para fabricar uma formulação farmacêutica estável.
BRPI0909198A2 (pt)	2019-09-24	composto antifolato, composto, método para preparar um composto antifolato, composição farmacêutica, método para tratar
BRPI0906475A2 (pt)	2015-07-14	Compostos, processso para a preparação de um composto, composição farmacêutica e uso de um composto
BRPI0910072A2 (pt)	2017-05-30	composto, composição farmaceutic, e, método para prover anestesia a um mamífero.
BRPI0814163A2 (pt)	2015-01-20	Processo para a preparação de compostos, forma cristalina, e, composição farmacêutica
BRPI0816904A2 (pt)	2015-03-17	Formas sólida, amorfa e cristalina, composição farmacêutica, e, método para tratar uma doença
BRPI1007161A2 (pt)	2016-02-23	composição farmacêutica oral, e processo para preparar uma composição
BR112012003280A2 (pt)	2017-05-23	composição farmacêutica para administração oral, método para tratar uma doença, uso do composto, e, composto.

Legal Events

Date	Code	Title	Description
2017-04-04	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2017-07-18	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]