BRPI0912927A2 - "método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo" - Google Patents
"método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo"Info
- Publication number
- BRPI0912927A2 BRPI0912927A2 BRPI0912927-8A BRPI0912927A BRPI0912927A2 BR PI0912927 A2 BRPI0912927 A2 BR PI0912927A2 BR PI0912927 A BRPI0912927 A BR PI0912927A BR PI0912927 A2 BRPI0912927 A2 BR PI0912927A2
- Authority
- BR
- Brazil
- Prior art keywords
- individual
- independent tumor
- vegf
- treating
- detecting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G01N33/575—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
"método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo" são fornecidos métodos para identificar ou diagnosticar tumor independente de vegfs e métodos para tratar tumor independente de vegfs.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9316108P | 2008-08-29 | 2008-08-29 | |
| US61/093,161 | 2008-08-29 | ||
| PCT/US2009/055434 WO2010025414A2 (en) | 2008-08-29 | 2009-08-28 | Diagnostics and treatments for vegf-independent tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0912927A2 true BRPI0912927A2 (pt) | 2019-10-01 |
Family
ID=41571323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0912927-8A BRPI0912927A2 (pt) | 2008-08-29 | 2009-08-28 | "método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo" |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100055099A1 (pt) |
| EP (1) | EP2321433A2 (pt) |
| JP (1) | JP2012501188A (pt) |
| KR (1) | KR20110068987A (pt) |
| CN (1) | CN102137939A (pt) |
| AR (1) | AR073231A1 (pt) |
| AU (1) | AU2009285540A1 (pt) |
| BR (1) | BRPI0912927A2 (pt) |
| CA (1) | CA2734172A1 (pt) |
| IL (1) | IL211088A0 (pt) |
| MX (1) | MX2011002082A (pt) |
| TW (1) | TW201012935A (pt) |
| WO (1) | WO2010025414A2 (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100135780A (ko) * | 2008-03-06 | 2010-12-27 | 제넨테크, 인크. | C-met 및 egfr 길항제로의 조합 요법 |
| ES2363358B1 (es) | 2009-04-03 | 2012-06-21 | FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al | Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable. |
| RU2582964C2 (ru) * | 2010-07-19 | 2016-04-27 | Ф.Хоффманн-Ля Рош Аг | Биомаркеры в плазме крови, предназначенные для комбинированных терапий с использованием бевацизумаба при лечении рака поджелудочной железы |
| WO2012151574A1 (en) * | 2011-05-05 | 2012-11-08 | Duke University | Methods of developing a prognosis for pancreatic cancer and predicting responsiveness to cancer therapeutics |
| CN103323601B (zh) * | 2012-03-22 | 2016-04-20 | 北京蛋白质组研究中心 | S100a9蛋白检测物在制备筛查肝细胞癌试剂盒中的应用 |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| CN103499694A (zh) * | 2013-10-14 | 2014-01-08 | 中南大学 | 检测结直肠癌及其恶性程度的免疫组化试剂盒 |
| WO2015148531A1 (en) * | 2014-03-24 | 2015-10-01 | Genentech, Inc. | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression |
| US9968688B2 (en) * | 2014-11-12 | 2018-05-15 | Verily Life Sciences Llc | Shielded targeting agents, methods, and in vivo diagnostic system |
| CA2966216A1 (en) * | 2014-11-14 | 2016-05-19 | Genentech, Inc. | Predicting response to a vegf antagonist |
| US10037603B2 (en) * | 2015-05-04 | 2018-07-31 | Siemens Healthcare Gmbh | Method and system for whole body bone removal and vascular visualization in medical image data |
| US11499973B2 (en) | 2016-05-17 | 2022-11-15 | Duke University | Methods of predicting responsiveness of a cancer to a VEGF targeting agent and methods of prognosing and treating cancer |
| JP6886854B2 (ja) * | 2017-04-13 | 2021-06-16 | シスメックス株式会社 | 被検物質の情報取得方法 |
| CN107807241A (zh) * | 2017-11-03 | 2018-03-16 | 太原瑞盛生物科技有限公司 | 一种血管内表皮生长因子受体1的磁微粒化学发光检测试剂盒及制备方法 |
| US11058345B2 (en) * | 2018-07-05 | 2021-07-13 | Boston Scientific Scimed, Inc. | Devices, systems, and methods for determining inflammation and/or fibrosis |
| EP4025910A4 (en) * | 2019-09-06 | 2024-02-07 | UT-Battelle, LLC | METHODS OF IMMUNOREGULATION BY MODULATING PLASMINOGEN-APPLE-NEMATODE DOMAIN (PAN) PROTEINS |
| WO2021207365A1 (en) * | 2020-04-07 | 2021-10-14 | The Wistar Institute Of Anatomy And Biology | Reawakening of dormant tumor cells by modified lipids derived from stress activated neutrophils |
| CN111583992B (zh) * | 2020-05-11 | 2023-08-29 | 广州金域医学检验中心有限公司 | Rna水平融合基因突变导致肿瘤的负荷分析系统和方法 |
| CN114958758B (zh) * | 2021-02-18 | 2024-04-23 | 南京启真基因工程有限公司 | 一种乳腺癌模型猪的构建方法及应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030206899A1 (en) * | 1991-03-29 | 2003-11-06 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| US6582959B2 (en) * | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| WO1994004679A1 (en) * | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US5686292A (en) * | 1995-06-02 | 1997-11-11 | Genentech, Inc. | Hepatocyte growth factor receptor antagonist antibodies and uses thereof |
| US5880141A (en) * | 1995-06-07 | 1999-03-09 | Sugen, Inc. | Benzylidene-Z-indoline compounds for the treatment of disease |
| US6884879B1 (en) * | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| US20020032315A1 (en) * | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| NZ500078A (en) * | 1997-04-07 | 2001-10-26 | Genentech Inc | Humanized anti-VEGF antibodies and their use in inhibiting VEGF-induced angiogenesis in mammals |
| US6297238B1 (en) * | 1999-04-06 | 2001-10-02 | Basf Aktiengesellschaft | Therapeutic agents |
| US6703020B1 (en) * | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| DE60042021D1 (de) * | 1999-07-29 | 2009-05-28 | Gilead Sciences Inc | Nukleinsäureliganden für den hepatozytischen wachstumsfaktor/dispersionsfaktor (hgf/sf) und seines c-met rezeptors |
| DE60128685T2 (de) * | 2000-06-23 | 2009-03-05 | Bayer Schering Pharma Aktiengesellschaft | Zusammensetzungen, die mit vegf/vegf und angiopoietin/tie rezeptor-funktionen interferieren |
| PE20030062A1 (es) * | 2001-05-30 | 2003-02-08 | Sugen Inc | Derivados aralquilsulfonil-3-(pirrol-2-ilmetiliden)-2-indolinona como inhibidores de quinasas |
| KR100883731B1 (ko) * | 2001-06-22 | 2009-02-12 | 기린 파마 가부시끼가이샤 | 간세포 증식 인자 수용체 자기 인산화를 저해하는 퀴놀린유도체 및 퀴나졸린 유도체 및 이들을 함유하는 의약 조성물 |
| EP1463507A1 (en) * | 2001-12-19 | 2004-10-06 | SmithKline Beecham Corporation | Thienopyrimidine compounds as protein tyrosine kinase inhibitors |
| US6790852B2 (en) * | 2002-04-18 | 2004-09-14 | Hoffmann-La Roche Inc. | 2-(2,6-dichlorophenyl)-diarylimidazoles |
| JP2006503864A (ja) * | 2002-10-01 | 2006-02-02 | ジヨンソン・アンド・ジヨンソン・フアーマシユーチカル・リサーチ・アンド・デベロツプメント・インコーポレーテツド | タンパク質チロシンキナーゼ阻害剤としての4,6−ジアミノ置換−2−[オキシ又はアミノキシ]−[1,3,5]トリアジン |
| CN103265477B (zh) * | 2003-02-26 | 2017-01-11 | 苏根公司 | 作为蛋白激酶抑制剂的氨基杂芳基化合物 |
| CA2522595A1 (en) * | 2003-04-03 | 2004-10-28 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
| US20050186208A1 (en) * | 2003-05-30 | 2005-08-25 | Genentech, Inc. | Treatment with anti-VEGF antibodies |
| WO2005005378A2 (en) * | 2003-07-02 | 2005-01-20 | Sugen, Inc. | Indolinone hydrazides as c-met inhibitors |
| US7122548B2 (en) * | 2003-07-02 | 2006-10-17 | Sugen, Inc. | Triazolotriazine compounds and uses thereof |
| US7758859B2 (en) * | 2003-08-01 | 2010-07-20 | Genentech, Inc. | Anti-VEGF antibodies |
| US20050106667A1 (en) * | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| WO2005016920A1 (en) * | 2003-08-15 | 2005-02-24 | Vertex Pharmaceuticals Incorporated | Pyrrole compositions useful as inhibitors of c-met |
| AU2004284420A1 (en) * | 2003-09-24 | 2005-05-06 | Vertex Pharmaceuticals Incorporated | 4-azole substituted imidazole compositions useful as inhibitors or c-Met receptor tyrosine kinase |
| US7626030B2 (en) * | 2004-01-23 | 2009-12-01 | Amgen Inc. | Compounds and methods of use |
| EP1751136B1 (en) * | 2004-05-07 | 2014-07-02 | Amgen Inc. | Nitrogenated heterocyclic derivatives as protein kinase modulators and use for the treatment of angiogenesis and cancer |
| US20060009360A1 (en) * | 2004-06-25 | 2006-01-12 | Robert Pifer | New adjuvant composition |
| CA2647430A1 (en) * | 2006-03-29 | 2007-10-11 | Genentech, Inc. | Diagnostics and treatments for tumors |
-
2009
- 2009-08-28 AR ARP090103324A patent/AR073231A1/es unknown
- 2009-08-28 EP EP09792080A patent/EP2321433A2/en not_active Withdrawn
- 2009-08-28 CA CA2734172A patent/CA2734172A1/en not_active Abandoned
- 2009-08-28 AU AU2009285540A patent/AU2009285540A1/en not_active Abandoned
- 2009-08-28 WO PCT/US2009/055434 patent/WO2010025414A2/en not_active Ceased
- 2009-08-28 MX MX2011002082A patent/MX2011002082A/es not_active Application Discontinuation
- 2009-08-28 JP JP2011525256A patent/JP2012501188A/ja active Pending
- 2009-08-28 KR KR1020117004581A patent/KR20110068987A/ko not_active Withdrawn
- 2009-08-28 TW TW098129171A patent/TW201012935A/zh unknown
- 2009-08-28 BR BRPI0912927-8A patent/BRPI0912927A2/pt not_active Application Discontinuation
- 2009-08-28 CN CN2009801338987A patent/CN102137939A/zh active Pending
- 2009-08-28 US US12/550,246 patent/US20100055099A1/en not_active Abandoned
-
2011
- 2011-02-06 IL IL211088A patent/IL211088A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2321433A2 (en) | 2011-05-18 |
| CA2734172A1 (en) | 2010-03-04 |
| AR073231A1 (es) | 2010-10-20 |
| AU2009285540A1 (en) | 2010-03-04 |
| TW201012935A (en) | 2010-04-01 |
| WO2010025414A3 (en) | 2010-05-14 |
| KR20110068987A (ko) | 2011-06-22 |
| WO2010025414A2 (en) | 2010-03-04 |
| JP2012501188A (ja) | 2012-01-19 |
| CN102137939A (zh) | 2011-07-27 |
| MX2011002082A (es) | 2011-06-20 |
| US20100055099A1 (en) | 2010-03-04 |
| IL211088A0 (en) | 2011-04-28 |
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| B350 | Update of information on the portal [chapter 15.35 patent gazette] |